Conserved Protein Domain Family
UBA_RHBD3

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cd14289: UBA_RHBD3 
UBA domain found in vertebrate rhomboid domain-containing protein 3 (RHBD3)
RHBD3 is encoded by a novel chromosome 22 CpG island-associated gene (C22orf3) that is not expressed in a significant proportion of pituitary tumors. C22orf3 is also called pituitary tumor apoptosis gene (PTAG) or RHBDD3 which is located directly upstream of EWSR1. Although its biological function remains unclear, RHBD3 contains an N-terminal rhomboid domain and a C-terminal ubiquitin-associated (UBA) domain.
Statistics
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PSSM-Id: 270475
Aligned: 4 rows
Threshold Bit Score: 81.4406
Created: 8-Aug-2012
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9Y3P4       327 LRLQQLERMGFPTEQAVVALAATGRVEGAVSLLVGGQVGTETLV 370 human
NP_001037981 305 LRLQQLERMGFPTGPAVLALAATGKVERAVSLLVEGQVGADIRV 348 western clawed frog
NP_001121831 296 LRLQQLEKMGFPTEKAVVALAATGQLDGAISLLIDDQIGEETVV 339 zebrafish
EMP25331     331 LRLQQLERMGFPTGRAVVALAATGRVEGAVSLLIGGQIGDKAVV 374 green seaturtle
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