Conserved Protein Domain Family
NRN1
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pfam15056: NRN1 
Neuritin protein family
The domain family Neuritin1 (NRN1) is a GPI-anchored protein expressed in post-mitotic-differentiating neurons in the developing nervous system. NRN1 is a glutamate and neurotrophin receptor target encoding a neuronal protein that functions extracellularly to modulate neurite outgrowth (OMIM:607409). This family of proteins is found in eukaryotes. Proteins in this family are typically between and 158 amino acids in length.
Links
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Statistics
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PSSM-Id: 434424
Aligned: 15 rows
Threshold Bit Score: 129.43
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_008115813  28 CQNIYQDFSDCILKLGENMASYEEEEEEEeektpvQGLHVVCGYWDEFHTCAMTALWEC-QREAVTIWEMLKKESTKIKF 106
XP_004069184  80 CENIYKDFSDCVLELGDSMDNYQENVTSE------RGVAAVCSHWEAFHTCALTALSDC-QEEVSSIWETLRQDSRKIRF 152
XP_016158664  27 CAGAYRGLSDCVLKLGDSMATYEEEEGIEl-----QGLHRVCRYWDEFHTCALTVLWEC-QKEAVAVWEMLRRESQKTKF 100
1_pfamImport   1 CENIYKGFSDCVLKLGENMGNYKEEGDET------QQLQIVCGYWEEFHICATTAISEC-QEEASRIWETLKKESKKIKF 73 
XP_015194387  33 CNGIYRGFSECLLRLGDSMSRYVEEelv-----eeQDIDNVCAHWDEFHACGMAVISEC-RVEVQAVWDSLRLQSENLRF 106
XP_009301502  26 CSAVYRGFAECLLTLGDSVSSKTDEn--------pQDINSICKSWDAFQVCVSGVLSGC-RGDAAEIWESLRAESRKTAF 96 
XP_008115872  32 CNTIYKGFAECLIRLGDSMAQSVQQQQGQdsnqeqQELDTICKSWDDFHTCATQVLSSC-PEEAANIWESLRQDSRKTQF 110
XP_015223863  32 CDSIYRGFAECLLRLGDSMTRSVQQgae-----dlQEIDTICRSWDEFHTCANAALAGC-PEEAAAVWESLRQESKKMQF 105
XP_014327598  34 CHSIYKGFARCLMALGDSLTENARKee------etHEIHSICRSWDEFHDCANVAMAGC-PEEAAAVWESLRQESKKMQF 106
XP_003226908 106 CDAVFKGFSDCVLKMGQNIALYQQDPDDK------KNLETICRYWDDFHACTLIALTDCqQEGVTDVWEKLKEKSKKLDY 179

XP_008115813 107 QGSLFDLCAPSDSQ 120
XP_004069184 153 QGSLFDLCSPSSSS 166
XP_016158664 101 QGSLFDLCSPSMAQ 114
1_pfamImport  74 QGSLFDLCSSNKS- 86 
XP_015194387 107 HGNLYEVCRAREQS 120
XP_009301502  97 AGNLYDICASRTEA 110
XP_008115872 111 QGNLHDLCSSRTQL 124
XP_015223863 106 SGNLYDMCSNRAKP 119
XP_014327598 107 SGNLYDMCSNRNSH 120
XP_003226908 180 EGNLFVLCSKTKAA 193
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