5IJO


Conserved Protein Domain Family
Nup188

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pfam10487: Nup188 
Nucleoporin subcomplex protein binding to Pom34
This is one of the many peptides that make up the nucleoporin complex (NPC), and is found across eukaryotes. The Nup188 subcomplex (Nic96p-Nup188p-Nup192p-Pom152p) is one of at least six that make up the NPC, and as such is symmetrically localized on both faces of the NPC at the nuclear end, being integrally bound to the C-terminus of Pom34p.
Statistics
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PSSM-Id: 463110
Aligned: 27 rows
Threshold Bit Score: 642.802
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5IJO_J         34 AELNKHWRRLLEGlS-YYKPPspssaEKVKANKD-----------VASPLKELGLRISKFLGLDEEQSVQLLQCYLQ--- 98  
Q7Q9K3         33 EKLFQVSKELVDG-IlHYKKPtk--aSEEKLQKLikd-------rnQLKLQPFANKLHQYLDIDAVQSWQILCYYLVn-- 100  Anopheles gam...
EKC37617       34 RELNRNKKKIING-LsFYKKPrcvqgEILKTKKlkk------------vtEEFLLKTSAFLGLDEGETYELFISYLSn-- 98  
XP_015134970   32 SELNKHWQRLLEG-LsYYKPPsttsaEKIKADKDvaa-----------plKELGLRVSKFLGLDEEQSVQLLQCYLQe-- 97  
F6WXT2         33 AELDRYGDRLLQG-LaYYRPPstsstGKVKANKNlsp-----------alQELGLRLSKFLGLDEEQSVELLQTYLLy-- 98   tropical claw...
XP_004178671   30 SCLNENKQLLLNP-S-IFNDYnh-skSTTTNPKTlnlrg--stytIAEDDFQTALMLNKYSNLSLNESLRVLSLRSVkir 104 
P52593         42 QFLKANKTNLIES-LnTIRQNvtssgDHNK----------------------LRSTIANLLQINV--------------- 83   Saccharomyces...
Q6FP54         33 AFLEKNKRQLLEL-Q--LGSNestkhNDNNDTKRiiarkilgydyDFEGSNE----------YNLNE------------- 86   [Candida] gla...
XP_002552412   34 KFLKDNKPLLLEP-A-KFNEL-----GAEVPSKTtplvigsakynISVENWKDASRLSRALNVSYEQSLRIVAQSDArsc 106 
Q6CNP1         32 KFLKDNEEILVHL-S-RFts----veNTDSVGKQlqlrg--ysynVTVEDEKLANELSIALNVHQKECLRVISQTRTrfp 103  Kluyveromyces...
5IJO_J         99 ---EDYRgtRDSVKtvlqderqsQali--lkIADYYYEERTCILRCVLHLLT---YFQDERHPYRVEYAdcvdkLEKE-- 168 
Q7Q9K3        101 ----EYRgaATALAeyistetsmVkll--hdIWTYHTLERMVQLKVMKNLLE---YFHSGTHPYSKEYRevvekMGLQal 171  Anopheles gam...
EKC37617       99 ----DYRgsKKELQqvlrnerlaHala--ykVRDYYYTERLYLLQSVKVIVN---SWQNNLHPFQRGFGtfmksTEVVsg 169 
XP_015134970   98 ----DYRgtRDSLKtvlqderqsQalm--lkLADYYYEERICILRCVLHLLT---YFQDERHPYTAQYFqcvekLD-Ke- 166 
F6WXT2         99 ----DYRgtQESVKgvpqderqsQalmlkasMVDYYYEERISLLRCVLYILN---YFQDDKHPYSAEFSkcvemMEQKe- 170  tropical claw...
XP_004178671  105 dtkIl-------------------------sLASYIYNERNSVWNSILLLLT-----ETSYPLIEKQYVeyfdsVNLEft 154 
P52593         84 ----------DNDPffaqsedlsH-------AVEFFMSERSSRLHIVYSLLVn--------PDIDLETYsfidnDRFNvv 138  Saccharomyces...
Q6FP54         87 -------------------------------FLEKELLERNSMVDIMVDLNTrrhICDRYIPDLNVNNAknedsL-TGri 134  [Candida] gla...
XP_002552412  107 le----------------kdrmfL-------YAQRILQERNAIVDAAFLILN----WDCKYVPAKEDLIstisiEKTTlc 159 
Q6CNP1        104 dcpMek-----------------------dtIVKQILHERNCVLDTTLVLLN-----HDSFPVLKGSMLqlvykNRSTmi 155  Kluyveromyces...
5IJO_J        169 --L-VSKYRQQFEELykteaptwe----------thgnlmterQvSRWFVQCLREQSMLLEIIFLYYAYFEMAPSDLLVL 235 
Q7Q9K3        172 rkSyLAQLTHLIADPpssqkapla-----------gdllhgqtR-VACAERRLRETNEILQILLLIVHYSGISPEELDQL 239  Anopheles gam...
EKC37617      170 -sL-MKMLLETFEQLtqepfptwe----------tnsilmndrQmYLWVQENLREQSEILEILYIYVKDFDLPEEQVLKL 237 
XP_015134970  167 --L-VPNYRKQFEELykaeaptwe----------thgnlmterQvSRWFVQCLREQSMLLEVIFLYYAYFEMAPDELLAF 233 
F6WXT2        171 --L-FGKYLKQFESLcreeaptwe----------thgnfmterQvSRWFVQRLREQAMLLEIIFLYFACFAASPSDLLAL 237  tropical claw...
XP_004178671  155 knI-VKYLQELMNNYlgveyttser---------vtrkdfeklK-ALRKSNDLITITLLLKLLTILYLRSNLPIEQTLDW 223 
P52593        139 gkL-ISIISSVIQNYdiitasslahdy----nndqdmftivslV-QLKKFSDLKFILQILQILNLMILNTKVPVDIVNQW 212  Saccharomyces...
Q6FP54        135 stV-IDVLLNTLTATnsvdecvlqcmdhleelhldnedtiqdiI-DLIINYNILYCFKLLKLLTLYIINRNVAVSLTQKW 212  [Candida] gla...
XP_002552412  160 shL-ISLLSDVAANFgsldknn--------------siwsqplQ-DLKDCQDVFYAIRIMELLTLLIMNSDTPVGIVSSW 223 
Q6CNP1        156 seA-ILLVKNCVALIgsaeq-------------------ndsyK-SSLMSYDLIYITNLLNLIAFVSLNQPVGLEIITKW 214  Kluyveromyces...
5IJO_J        236 T-----KMFK------------EQGfgsrqtNrHLVD--ETMDPFVDRIGYFSALILVEGMDI-----ESLHKCALDDrr 291 
Q7Q9K3        240 F-----KLFR------------EHSfgkqqeHlDPGS--EIHAELVKRITYNELALVFRTLDL-----SDKFDDAGW--- 292  Anopheles gam...
EKC37617      238 L-----ELFK------------RHGfgrlqnYkHVID--DSLIFLVKRIGYLEVLICVEMMDL-----EAVLACIERGsf 293 
XP_015134970  234 A-----KLFK------------EQGfgtrqtNrHLVD--ESMDHLVDRIGYFSALILVEGMEI-----DSLHERALDDrt 289 
F6WXT2        238 T-----KLFK------------EQGfgcrlqNrHLVE--PSMDPLVERIGYFSVLIFLEALDI-----ETLMTCSLSDkt 293  tropical claw...
XP_004178671  224 V-----TFLE------------SLKlfyntlY---MEnnKFDAKVISTIKSLVSINGLIVLGLdt--tTFSIKPDIP--- 278 
P52593        213 FlqyqnQFVEfcrninstdksiDTSslqlykFqNFQDlsYLSETLISRISSLFTITTILILGLnt--sIAQFDIQSP--- 287  Saccharomyces...
Q6FP54        213 F-----SNFSeivnqvtlisstHSNr----rFlDNTErsMVDTLFIAKLESTISIVSIVFLGLssareDSNLNMDTD--- 280  [Candida] gla...
XP_002552412  224 C-----SVLK------------TTNy-----FqCFSEvaTMPREVPDKLEALATINTVLMLGFdv--sTFTIKVESP--- 276 
Q6CNP1        215 Y-----ELLE------------ETQy-----FaILKDnkDVPSEIYNMANSLMIMDTIIMTGYnt--sEDTIDVKSS--- 267  Kluyveromyces...
5IJO_J        292 elhqFAQDGLICQDMDCLMLT-------FGDiphHAPVLLAWALL---RHTLNPEETSS----VVRKI------------ 345 
Q7Q9K3        293 -------IERVVAALDGPMVS-------LHQfpeHGPLLLVWMLFnfrLQHTVEDEDTTrry------------------ 340  Anopheles gam...
EKC37617      294 ndhfLLKDKETFMKLDKVVQT-------LGSedsHGPLLLLWSAM---HMFGGEGSDFSlar------------------ 345 
XP_015134970  290 eehkLANNSHIHQEMDNQLLQ-------LGDvshHAPVLLAWALL---RHTINPEESANvir------------------ 341 
F6WXT2        294 eqhpFSSEEQVCKEMDSVLVT-------LGDaphHGPVLLAWALL---RFALNADKVTPtvr------------------ 345  tropical claw...
XP_004178671  279 ----YFTDSSSFKQLQMLLVN-------SD----DPLLLYMWSFIlftKSCLLEETPE-----TEFQFikdvfddipisn 338 
P52593        288 ----LYMDTETFDTVNSALENdvatnivNEDpifHPMIHYSWSFIlyyRRALQSSesfdds------------------- 344  Saccharomyces...
Q6FP54        281 ----FLHDVATFELVHSVLLD-------EMHkkrMPIVLYMWSFIlcaKSIIAEDDSDEitsiNELDFirkcfpqdsihs 349  [Candida] gla...
XP_002552412  277 ----FFNDPECFKTVNKTLLD-------QPS---SAIILYYWSFVlslKSYLFEEYPE-----KNAKFldnvfgtvpvsh 337 
Q6CNP1        268 ----FFNDAATFRRLLDLIIN-------TDP---PAIIVYYWSFIlysKSYLLEEDPE-----NNLEFvqqvfnsqpisk 328  Kluyveromyces...
5IJO_J        346 -----GGTAIQLNVFQYLTRLLQ---SLasGGNDCTTSTACMCVYGLLSFV-LTSLElhtlg--nqqdIIDTACEVLADP 414 
Q7Q9K3        341 --qqlGSRAIKLGVFEYLHAIVSh-pMF--KDQSLTARIVRKSIFNHLGFLcQLFDAdesia--hhsnIYDLLSELLTSP 413  Anopheles gam...
EKC37617      346 ---kyGNAAIHLHVFHYLYNLLMsepFN--EENSMICSVSHLTVYNLLVLIlSTFDEhtlgtdqdalaLHRVICLVLKQV 420 
XP_015134970  342 ---rmGSTAIQLNVFQYLTKLLKs-lSS--GGKNCTASTACMCIYGLLSFVlTSLELhtlg---nqqdIIDAACEVLAAS 412 
F6WXT2        346 ---kmGSTAIQLHIFQYLTRMLQs-lRS--GENNCTTSTACLCVYTFLTFVlTNLEEqvlq---sqqdLVDTAFQVFAAP 416  tropical claw...
XP_004178671  339 lttqfATKAESLNIFQTLRNVTK---AI--TSNSVYSTILCSYLSLALNFI-PINIE-----------MSEIIRDVLLRT 401 
P52593        345 ditkfALFAESHDVLQKLNTLSE---IL--SFDPVYTTVITVFLEFSLNFI-PITAS-----------TSRVFAKIISKA 407  Saccharomyces...
Q6FP54        350 msilfAKNAEDIGLLAKFLETSN---CI--RNDNIFTTLFASFMTLSVNFI-PFTAS-----------TTKIIKSVLNDL 412  [Candida] gla...
XP_002552412  338 lislmVKRSEELDVLASFTKFSG---CL--EQDKLWSVTLSSLMALSLNFI-NITPQ-----------AAKTVKELLTKN 400 
Q6CNP1        329 likefALTAENENVFEEISKVSQ---IF--KDQAFFAAILTSFITFSLYFV-PISIK-----------TSKMIKTVLSNA 391  Kluyveromyces...
5IJO_J        415 --SLPELFWGT--------------------EPTsglGIILDSVCGMFPHLlspLLQLLRALVSGKSTAkkvY------- 465 
Q7Q9K3        414 t--IATEFCKIe------------------dHPI---RALFNICLEHFPVEftpLSKVAYALASAGSSQ---Nky----- 462  Anopheles gam...
EKC37617      421 s--VSEDFWEKailmnlflpflkypklqgsdEGV---GSVYHSALLRFPLDyssFVQFSAALAESTPTS---Aerasllw 492 
XP_015134970  413 s--IPQLFWKTep-----------------tAGL---GIILDSVCGMFPHLltpLLQLLQALVSDKSTA---Kkv----- 462 
F6WXT2        417 n--LPDLFWNMep-----------------tAGL---GILLDSVVGMFPFHlspLLKLFTALVS-KSSA---Kkv----- 465  tropical claw...
XP_004178671  402 piEFVEKFLIS--------------------PSF---DKKVKILTGKLPLVteaLIPLINISSVHPEFA---D------- 448 
P52593        408 peQFIENFLTN--------------------DTF---EKKLSIIKAKLPLLnesLIPLINLALIDTEFA---N------- 454  Saccharomyces...
Q6FP54        413 prGVIENFISN--------------------NAF---ITKFDTIKAKLPLIdegLLPFINLTSINEELA---E------- 459  [Candida] gla...
XP_002552412  401 prSFVEKFLTN--------------------NEV---EKKVALLRAKVPLLeegLLPLIHFSTVHPDFA---N------- 447 
Q6CNP1        392 ptHYVEKFLTN--------------------KEF---EKKFFLIKTKAPLLkesLIPMINITSANAEFA---N------- 438  Kluyveromyces...
5IJO_J        466 ----SFLDKMSFY-NELYK--HKPHDVISHEDG--------------TLWRRQTPKLLYPL----GGQTNLRIPQGTVGQ 520 
Q7Q9K3        463 --iqELLENLPVY-TELYTgqNQYEIRKAASSNe-------------DEFIMCHD---YTPs----sKINFTIPRGTKLI 519  Anopheles gam...
EKC37617      493 gkvfHIWKQLQRY-TEYLDc-NHSSDLTSTKEL--------------NEWKLVVN---KRPy----pTRDFILNAGTKGK 549 
XP_015134970  463 ---ySFLDKMSFY-IE-LYk-HKPPDVISHEDG--------------TLWRRQAP---KLLyplgLGQTNLRIPQGTVGQ 519 
F6WXT2        466 ---ySFLDRMSSY-TE-HYr-HKPHDILSHEDE--------------TLWKRQTP---KVLyalgLGQTNLRIPQGTIGQ 522  tropical claw...
XP_004178671  449 ----FQWNSINTY-MVELKl-GELN--YDLVDDdnts-------mssDYIVLKTELLVTPPfe-tDENCKLPLPAGTKGK 512 
P52593        455 ----FELKDICSFaVTKSSl-NDLD--YDLIADtitnsssssdiivpDLIELKSDLLVAPPleneNSNCLLSIPKSTKGK 527  Saccharomyces...
Q6FP54        460 ----FNWEAFGSY-AVKMPl-GSID--YDVADRsnsnd-----sstlEQIQLSSEVLVKPPfe-qDDDVLMPLPKSTKAF 525  [Candida] gla...
XP_002552412  448 ----FEWKELNTY-TEKLRl-SSLS--YDLADLpgpt------sessDIIVLKQELLVKPPle-sQSNVMMPIPKETRGK 512 
Q6CNP1        439 ----FEWKELPTY-VQEVVl-GSLE--YDLADDah----------stDLISIKSETFARVPle-pSGNVLLPIPKDTKAK 499  Kluyveromyces...
5IJO_J        521 VM-------------------LDDRAy-------------LVRWEYSYSSWTLFTCEIEMLLHVVSt--------ADVIQ 560 
Q7Q9K3        520 VRd-----------------lHNQRT--------------YVHFSTGYNYFNALHHEINELLEdaqa-----tstLNSER 563  Anopheles gam...
EKC37617      550 ILtm----------------gTKHDAs------------pIIQWYVTFSGWDLLLCEVETLLDQVAqgsgmvsptQ---- 597 
XP_015134970  520 VM-------------------LDDRAy-------------LVRWEYSYSSWTLFTCEIEMLLHVVSta-----dvIQ--H 560 
F6WXT2        523 VM-------------------ADEHGf-------------LVRWEYSYSCWTLFTCEIEMLLHVVSta-----dvIH--Q 563  tropical claw...
XP_004178671  513 IIpi---------------vnSTEDD--------------VIIFSFQYNGWSMIGRILQNICVSYVekn----tdLSELE 559 
P52593        528 ILti----------------kQQQQQqqqqngqqppttsnLIIFLYKFNGWSLVGRILQNLLHSYMekg----tqLDDLQ 587  Saccharomyces...
Q6FP54        526 IVadvpaitsgkehtkdsivkYNSEDgssnfttnnvtnetLLVFDYQYNGWSLLGRILQNLSILYTvkg----ndINYEQ 601  [Candida] gla...
XP_002552412  513 IIpi----------------tSTAED--------------AVVFMHDYNGWSLLGRILQNICDTYTqse---edeAKREK 559 
Q6CNP1        500 ILp-----------------sVTNDD--------------VVMFLYKYNGWSLLGRVLQNACDRYLstss--agvQDSDV 546  Kluyveromyces...
5IJO_J        561 hCQRVKPIIDLVHKVIsTDLSIADCL-L-------------------PITSRIYMLLQRltTVISPPVDVIASCVNCLTV 620 
Q7Q9K3        564 -VQRIATGLKYLAVAVrRIQQPHDITaEm-----------------vHPTEMVFDVLLKfrAVPNPPVDLLVQCLNVCTA 625  Anopheles gam...
EKC37617      598 -IEKVTDAVELVHAVLkNHPHSEKDF-Q-------------------PIIHCIYSLIHRfvRLSHPPILLIVQCIECVTC 656 
XP_015134970  561 -CQRVKPIIDLVHKVIsTDVSVADCL-L-------------------PITSRIYMLLQRltTVISPPMDVIASCVNCLTV 619 
F6WXT2        564 -CQRVKPIIDLVHKVIsTDLSIADCL-L-------------------PITSRIYMLLQRltTVMNPPMDFLSSCVDCLAA 622  tropical claw...
XP_004178671  560 -EKILCSIVQLISTIGsSYISKEKYE-Diveqls-------sfvsqnDIFTIFFRIFEH--SLQKRKYSLLTIFMHSLPI 628 
P52593        588 -HELMISIIKLVTNVVdPKTSIEKSS-EilsylsnsldtsastingaSIIQVIFEIFEI--SLQRKDYTSIVQCCEFMTM 663  Saccharomyces...
Q6FP54        602 -KEFMIAAISLLSNIMsSTIPVDHSI-Kileslssq----lskprddDIISVVFKIFER--ALHKRNYELLCICASFTNV 673  [Candida] gla...
XP_002552412  560 -SELAVAIIDLVANTMgAETPIERST-Eilqhls-------gyveddDIISVLFKLFEL--ALHSRNLPIINAGLNLMIE 628 
Q6CNP1        547 -QEMILSMLDLISSVIgSGISVEKSA-Dillqms-------tyltedYIFDVIFKVFEQ--SLHLRDYDVIDHCLNLLIS 615  Kluyveromyces...
5IJO_J        621 LAARNPAKVWTDLRHTGFLPFVAhpvsslsqmisaegmN---------------AGGYGNLLMNSEQPQGEYGVTIAFLR 685 
Q7Q9K3        626 LVPLFEQEIYTRIINLNILPSVN---------------NanltyqdyangvgydSSLIGYYLMNVERNAGRYPILMAYFN 690  Anopheles gam...
EKC37617      657 LAKQNPVKVWHNMKQTGLLPYLT---------------EnidniseilsgqglmAGCYGNMLFGVECIEGSYPITTAVLE 721 
XP_015134970  620 LAARMPAKVWTDLHHTGFLPFVA---------------NpvssmnhmisaegmnAGGYGNLLMSIEQPQGEYSVTISFLN 684 
F6WXT2        623 LATRMPAKVWIDLRHTGFLPFAA---------------Npvsghii--stegmnAGGYGSLF-GIEQSQGEYSITLSFLR 684  tropical claw...
XP_004178671  629 LFTHSPSIIWSYLTSSELLDRHG---------------K---------------NGMVTSILGSLEIPTGDYEFTIVLSK 678 
P52593        664 LTPNYLHLVSSYLNKSDLLDKYG---------------K---------------TGLSNMILGSVELSTGDYTFTIQLLK 713  Saccharomyces...
Q6FP54        674 LVRRFPHFVWAYLSTSDLLDHYG---------------K---------------SGLVNIILGSIELTNGEYDFTISIAK 723  [Candida] gla...
XP_002552412  629 LTPNFSHFVWTHLARSYLIDRNG---------------K---------------EGLAISILGNIERTSGVFQSSILLIK 678 
Q6CNP1        616 SIDDFSQFVWSHLARSELLDRYG---------------K---------------SGLISSVLGTMELPNGNYSITIKIIK 665  Kluyveromyces...
5IJO_J        686 LITTLVKG----------QLGSTQSQGLVPCVMFVLKEMLPSYHKWRYN-SHGVREQIGCLILELIHAILNLCHET---D 751 
Q7Q9K3        691 FLKTYTKLgr------dnVFGVE-----LPGAIFLLREVLPYANNWRFE-TSSDRYRVLVFVVQYIYEILQLSEDKlesD 758  Anopheles gam...
EKC37617      722 FISNIIEP----------FFKDSMESELMASFMYILREIFPVFQKWRFY-KLKTRELIGRKCVEIFHKTLENVINr---S 787 
XP_015134970  685 LITTLVRG----------QLGSTQSQGLVPCIVFVLKEMLPNYHKWRYN-SHGVREKIGCLILQLIHAILNLCPEmdp-- 751 
F6WXT2        685 LVTTLVKG----------QLGSTQSQGLVPCILFVLREMLPNYHRWRYN-SHGVREQLGFQILSLIHAILNLSPEee--- 750  tropical claw...
XP_004178671  679 LADKLVQNslm----lnsDYSVRAKQDVIYKLTLHLLHVYESYQFWIYS-DRQQRYDLGYYLTSFFSQMVHHVYGI---D 750 
P52593        714 LTKVFIREslsl---kniHISKRSKIDIINKLILHAIHIFESYYNWKYN-NFLQKFEIAFHLTLIFYDVLHDVFTInph- 788  Saccharomyces...
Q6FP54        724 MTVGLIDDavttslysdsGVPLKTKKSILSNLIVHLLNVYESFQFWKYSkSIEQRFELSLELTKAFSKILYFVHGI---D 800  [Candida] gla...
XP_002552412  679 LASCLVSEslt----atdIFPERMKKEILGHLMAHLINIYEGFQFQTYT-MQWQYLEIGLQLTSLISKVLFAVYGV---D 750 
Q6CNP1        666 LAQQLVLEslt----letEFPENLKKEILSKFFQHFIHVYESYQYWNYR-SIAEKYELGTNLTILFTTVVYNIYGI---D 737  Kluyveromyces...
5IJO_J        752 LHS------SHTPSLQFLCICSLAYTE------AGQTVINIMGIGVD-TIDMVMaaqprsdgaEGQGQ-------GQLLI 811 
Q7Q9K3        759 YARr---------VLRDACVYSLLNRD------NGMVLLKIVGLGNG-YLQAVM---------ERESNwml--vpEQQLN 811  Anopheles gam...
EKC37617      788 KPVest---skrPKVQEVVVYSLLFTE------AGQTLLGIIATGSD-NVDQAL---------VQQGSmae-ggiGAEMI 847 
XP_015134970  752 -------rsSNAPSLQSLCIFSLANTE------AGQAVINIMGIGVD-TIDMVM---------ASQSSsdesqgqGQLLI 808 
F6WXT2        751 -------esTSTPNLQSLCIFSLTNTE------AGQAVINIMGVGVD-TLNAVM---------LTQAGssgtegqGQMLM 807  tropical claw...
XP_004178671  751 SESklkdkfTSVISEASERIVETFLNAqspdvqAARTLSTVILSSNS-DLNSAA---------NYQSL-------SQTFK 813 
P52593        789 ------qkdQLIISSSANKLLQLFLTPmdsidlAPNTLTNILISPLN-TTTKIL---------GDKIL-------GNLYS 845  Saccharomyces...
Q6FP54        801 SETppenkiTNVLSKAADTITNAFLVPdsydppVVISLINTITSPKN-KTIYIF---------GNGLF-------DELYD 863  [Candida] gla...
XP_002552412  751 FTTspskkvTGVLADAAQIAVGAFLGAstsemrAANSLITIVTFAKN-TNVPLH---------RGLPF-------GEMRH 813 
Q6CNP1        738 PSNppetkiTKVLSSAANDITNRFLSSdspdvrTVTSILHVLLSSNSlEALSIG---------NEVFY--------NKYN 800  Kluyveromyces...
5IJO_J        812 KTVKLAFSVTNNVIRLKPPSN---VV-SPLEQALSQHGAhgnN-----LIAVLA--KYIYHKHDpalprlAIQLLKRLaT 880 
Q7Q9K3        812 LMIQHSMTILMQILRLKRHIHeydLS--PLESAIYTQPK---QrdtlrIIPMVT--GYMSNIFNprlpilSCRLLRRF-A 883  Anopheles gam...
EKC37617      848 RLIQISFSVLNQLLLLKSPDLpl----sPVESALSSQPV---VrqnqhIVATIA--QYIYHKHNprlpmlACLLLKRL-A 917 
XP_015134970  809 QTVKLAFSVTNNVIRLKPPSSvv----sPLEQALTQH-----GahgnnLIAVLA--KYIYHKHDpalprlAIQLLKRL-A 876 
F6WXT2        808 QTIKLAFSITNNVIRLKPLSSai----sPLEHALTQH-----GahgnnLIAVLA--KYIYHKYDpslprlAIQLLKRL-A 875  tropical claw...
XP_004178671  814 KVIYLSYKFSNLLIAVRGSLH---YPpSTFEKILFIKSP---E-----LVELYN--KNSALKAN------VIQLFDSL-V 873 
P52593        846 KVMNNSFKLCTLLIAIRGSNRd--LKpSNLEKLLFINSS---K-----LVDVYTlpSYVHFKVQ------IIELLSYL-V 908  Saccharomyces...
Q6FP54        864 HVVQKAYDLANLLVSIRGVSK---LNaSSLERMLFCQSP---K-----LIDIYL--TKPTLKIS------IVKLLNSL-V 923  [Candida] gla...
XP_002552412  814 SLIDQSFELANLLISVRSLLH---LPpSSLERSFFIHSA---T-----LVDIYA--SHLGLRVE------VIKLLTHL-V 873 
Q6CNP1        801 QCLLKSYELANLLISVRAMLQ---LPpSTLESQIYGNLP---K-----LIDIYA--LHNDLRNP------IIKLMTHL-V 860  Kluyveromyces...
5IJO_J        881 -VAPM-----SVYACLGNDAA-AIRDAFLTRLQSKIEDMRIKVMILEFLTVAVE-TQPGLIELFLNLEV 941 
Q7Q9K3        884 iEFRM-----SLLACLDMEPD-QIRHTFLERLHDEIESDDLKLAVLEFVESCVH-KQPGLTEAFFKvny 945  Anopheles gambiae str. PEST
EKC37617      918 lVTKM-----SILSCFGGAAE-SVRDMYLNRLQGATEDLKLKVSILEFLSVCVE-AQPGLIEMFLNVQL 979 
XP_015134970  877 tVAPM-----SVYACLGSDAA-AIRDAFLTRLQSKIEDMRIKVMILEFLTVAVE-TQPGLIELFLNLEV 938 
F6WXT2        876 mVAPM-----SVYACLGSDAA-AIRDAFLSRLRDNIEDMQIKIMILEFLTVAVE-TQPGLIELFLNLEV 937  tropical clawed frog
XP_004178671  874 -GIPWtdnypFLLSYLGKDHSkLFLNAISLDLKSKITSHRLLKNIYSFFSTLMGsKQDGLAILFLTGSI 941 
P52593        909 -EAPWnddypFLLSFLGEAKSmAFLKEVLSDLSSPVQDWNLLRSLYIFFTTLLEsKQDGLSILFLTGQF 976  Saccharomyces cerevisiae...
Q6FP54        924 -GVPWsseypFLYSYLGHTYSeKFLSSIIKDLTTTLQDYQLAKTLYVFFGTLIRsKQDGLSILFLTGRA 991  [Candida] glabrata
XP_002552412  874 -RAPFdtdapSLLAYLGDDHSkMLLNCIAYDLKAPLLNQKLSKSLYSFFSAIMEgKQDGLAILFLTGKl 941 
Q6CNP1        861 -RAPWaenfpSLLSYLGQKHSkMIFNSILYDLASTIDDYQFLKSLYRFFSSVMEgKQDGFSILLVTGET 928  Kluyveromyces lactis
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