Conserved Protein Domain Family
FAM124

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pfam15067: FAM124 
FAM124 family
The exact function of this protein family remains unknown. This family of proteins is found in eukaryotes. Proteins in this family are approximately 480 amino acids in length. There is a conserved LFL sequence motif.
Statistics
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PSSM-Id: 464482
Aligned: 26 rows
Threshold Bit Score: 209.046
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDV25316      50 CIIHCEFENGLKKKMERLYRPMLDYINSTRQCISIE------------DDSKr---------SFNRSRnSSSSSEDinqf 108
XP_011221296  46 VSIHIIADPGESQPLQEAIDKVLAWIHPDLQLFRVS------------ERRA----------SRRRRK-PWKVAQP---- 98 
XP_010727089  30 VSVHIITDPGESKTLQQAIDKLLAWIHPELQLFRVS------------ERRVskkhrkp---------dntgvsqP---- 84 
XP_008115387 108 vsMHIIANPGESALLQQAIDNLLTWIHPDLQLFRVS------------ERRLprrprrl---------hkaitsqP---- 162
Q6DIL6        25 VSIHIIADPGESKCLQEAIDRLLVWIHPDLQLFCVS------------ERRVlkkkkps----------ksfashP---- 78  tropical clawed...
XP_001631892  52 CTLQIRTQKGEGGFLKNLYRPLLEGIDPTFQFICIE------------ESED--------------------VKYPltvw 99 
EKC34258     129 LTVHFLADSHEVYPMMDMYQPVIDWVDPDLHIFKVS------------ERINis-------eQRADDFtYSESSIP---- 185
EEN48992      13 ITIHFIVDPGENTRTRRTLQPLLDWFDADLQLFCIA------------ERGRkkrrpssavqNGVNGHnHDAPRYP---- 76 
XP_014350260  38 VSVHIITDPGNARTFQNAIDNLLAWINPELQLFRVS------------ERGIckkqkks---------csgivvqP---- 92 
CAG08281      14 VSVHLIADPGEGRILQRAADSILACVHPDLQLFRVSeraalarrpgarQRQSaelg---------------parqP---- 74  spotted green p...
EDV25316     109 dv------gkpkilSLGIQLFLHECn-YGnyHDNI---RNYLQQSIWNIKLNVAlSSTyiKSCPPNDNLESYVANGPMMP 178
XP_011221296  99 --------------ALAVVLFLQEE--YG--EEQIlrlHRTLQRPPWRHHHTER-VPG--RFLPYLPCSQDFFTLAPGTP 157
XP_010727089  85 --------------ALAIILFLQEE--YG--EEPIlqlHETFQRPPWHYHHTER-VHG--KFLPYMPCSQDFYTLAPETP 143
XP_008115387 163 --------------ALAVILFLQED--FD--GEPIlqlHESFQSPPWHYHHTER-VHG--KFLPYMPGSQDFFILVPGTP 221
Q6DIL6        79 --------------ALAIILFLQED--YG--EEQIlhlHKCFQKPPWQFHHTER-VHG--KFLPYMPCNQDFFTLANGTP 137 tropical clawed...
XP_001631892 100 genlprssdnfvctSLSVVLFLRET--FG--RLSAlsmQKNLGAEPWRFHHRIE-LPL--DVRPRVTARQDFYQAFPELP 172
EKC34258     186 --------------STAVMIFLHEEgmLG--CERIqtaKIHFEKSPWKFHHSEQvSRG--RVNPYPYNSQDFFYTSEDLP 247
EEN48992      77 --------------SLAIMLFYHEE--LA--RDKIsqvHECFKKPPWRFHHKAM-PSG--NVLPYPPNNQDFFTFAEDMP 135
XP_014350260  93 --------------ALAVILFLQEE--YG--EEQIlqlYKSFQQPPWRYHHTEH-VQG--KILPYMPCNQDFFTLANGTP 151
CAG08281      75 --------------ALALILFLQEA--CGgeEEELlalRRALRRPPWRYHHTET-VSSr-RMLPLSPGSQDFFTLAPGTP 136 spotted green p...
EDV25316     179 WWAIRTIHSGKEVIRINLFVN--DLDNMLQFYEVILRQQPQIKRKDFCCFTLVRYPEFDFQFSLKALNKlSPKPTPTDDF 256
XP_011221296 158 LWAIRPVHYGKEIVRFTIYCRhdNYADILKFYELILRRSPSQRKTDFCIFPIFSNLDVDIQFSLKRLPC-DQTPVPTDSS 236
XP_010727089 144 LWAIRPVHYGKEIIRFTIYCRneNFVDILKFYELILKRPVCQKKADFCVFPVYSNMEIDIQFSLKKLPK-GHTPMPTESA 222
XP_008115387 222 LWAIRPVHYGKEIIRFTVYCRheNFASTMKLYELVLKRQPHQQKADFCVFPIYSNVDIDVQFSLKKLPR-GLVPTPTESA 300
Q6DIL6       138 LWAIRQVHYGKEIIRFTIYCSyeNFADMMKMYELIIKKRVWRKKTDFCVFPVYSNMDFDIEFSLKRLVK-GQKPVPLESS 216 tropical clawed...
XP_001631892 173 LWAISPVHYGNEHLRFHIVVK--NFNQMKYFYELLTGVKPRGNSPGFCYFPIYTQKGLDIQISLKCLPQ--VSPRPSSGY 248
EKC34258     248 LWAVRQVHYGKEHIRLVIFAGeeNWDDMVHFYKLIIGTDPELLREDFCLFTVHTHTHYDIQFALKRLQR-GIKPRPLECV 326
EEN48992     136 LWAARQVHYGTEHVRFVLFCSrqNWEDMISFYKMILRKDMDVRKTDFCCFVVYSQPGLDVQFALKMLPD-NTKPKHVDSA 214
XP_014350260 152 LWAIRQVHYGKEIVRFTIYCSyeNFADMVRLYKMIVKKEGCQRKLDFCFFTVYSNMDIEIQFSLKRLPK-GQYPTPTESA 230
CAG08281     137 LWALRQVHYGREIVRFTVYCQhqNYGDTVRLYRLLLRRRVWQRKEDFCFFLLYSNPRLEIQLSFKRLPP-GRRPAVLESA 215 spotted green p...
EDV25316     257 LLEFFHTGYSSLVNLLPDCVTLVSKKCWKIKDPEGNTLLLH 297
XP_011221296 237 VLEFRVKDIGELVPLLPNPCSPISEGRWQTEDLDGNKILLQ 277
XP_010727089 223 VLEFRVKDVGQLVPLLPNPCSPISEGRWQTEDHDGNRILLQ 263
XP_008115387 301 VLEFRVEDIRKLLLLLPYPCSPLSEGRWQTEDPDGNKILLQ 341
Q6DIL6       217 LLEFRVRDFGQLIPLLPNQCSPISEGRWKTEDHDGNKILLQ 257 tropical clawed frog
XP_001631892 249 KLQFKVENVGSLAPYCGGPLLPYGRNSWMTNDPDGNYVILE 289
EKC34258     327 KLQFRVTDVGHIVPLFPNVCKPLSDTRWETKDHDGNTIVLE 367
EEN48992     215 IMQFRVKEIGQLVPLLPNVCSPISDVRWQTTDYEGNKILLE 255
XP_014350260 231 VLEFRVKDIGQLVPLLPNPCTPISEVRWQTEDYDGNKILLQ 271
CAG08281     216 LLEVRVRDVGALVPLLPRPCSPISQVRWRTEDYDGNQILLQ 256 spotted green pufferfish
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