5ZIB


Conserved Protein Domain Family
Glyco_transf_18

?
pfam15024: Glyco_transf_18 
Click on image for an interactive view with Cn3D
Glycosyltransferase family 18
Enzymes belonging to glycosyltransferase family 18 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase) contribute to the creation of branches in complex-type N-glycans. This domain is responsible for the catalytic activity of the enzyme.
Statistics
?
PSSM-Id: 434401
Aligned: 24 rows
Threshold Bit Score: 847.333
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
5ZIB_A        57 CYA-DYGVDG-STCSFFIYLSEVENWCPHLPWRAkNPYeEADHN---SLAEIRTDFNILYSMMKKHE---EFRWMRLRIR 128
8_pfamImport   1 CYA-DWGVDG-SDCTIYHYLSQVEHWCPPTGKNInSTKsVRS-----KAKIMKQNFTELFKILGRDI---QYKWIKMRMR 70 
XP_009859453 172 CYA-KWGVDG-SDCTIYHYLSEVEHWCPPVDKTNtTSAeQIKMSkptKPLVFNQNFTDLYAILGRDV---QYKWIKMRMR 246
XP_014325082 191 CYS-SYGVNG-SLCSFLIYLSETESWCPVLPDRVsVIEeTKQPVl--EDAVIRGHFEGLHQFLDNKT---EFKWIQQRIK 263
CAF91608      34 CYR-NNGVNG-SVCSILIYLSEVENWCPLLPGRViPMAsTQHTEt--GQAVIRESLQGLSPELLNRN---QYKWIHQRIL 106
ESN93534      15 CYA-EYGVDG-GMCSIRYYLSEIENWCPPLPANStFKPiT-------HKASWNKNLTQLLSLINQSEskdNYAWIMDRIE 85 
XP_001629644  12 CIVeEHKVDPfDMCSIIIYLSEVEAWCPILPARRkLPQnAPARR---KKAFLERANHNLMDRMKQD----HWRWMRQRIK 84 
XP_001641454 173 CYAkDHGVNG-TICSFLVYLSEVENWCPKFPGRMkPTSrATTE----GADLHRSDVQGLLGLLNDQDp-iKFKWIKNRIN 246
Q9NDH7        99 CYI-ENHIDG-SECSFRYYLSQVENYCPPMEHHGkRK----------GLAKISPSIRRLLPIFES-----IPHYMKTRIN 161 Caenorhabditis ...
CAP31593      99 CYA-DNYIDG-SECSFRYYLSQVENYCPPMTETIrRN----------GLAKMSPSIRRLLPIFDG-----IPVYMRTRIN 161
5ZIB_A       129 R-MADAW----IQAIKSLAEK-QNLEKRKRKK--VLVHLGLLTKESGFKIAETAFSGGPLGELVQWSDLITSLYLLGHDI 200
8_pfamImport  71 R-MQGSW----LEAAQSLAAK-FDTGKWKKKKasVLLLLGLLAKETGFKIADNAFKGGPLGELVQWSDLISALYVLGHEI 144
XP_009859453 247 R-MERSW----LEAVSSLKEK-FDAGNWKQKK--VLLVLGLLAKETGFKIADNAFKGGPLGELVQWSDLITALYVLGHDI 318
XP_014325082 264 S-MEEIW----LEAGRSLSAK-YNLEDRKAKQ--ILVHPGVLTKEAGLKIAENAFSGGPLGELVQWSDLISSLHVLGHHL 335
CAF91608     107 S-MEDIW----LKAGRSLSAQ-YNLKDRKAKR--ILVHPGAVLNEVG--IATAAFSGGPLGELVQWSDLISALHLLGHQV 176
ESN93534      86 RsLWHLWsdavVSFQRDKEFL-LDNKMRSKRK--ILIYLGFLSKKSGFRIQQSATAGGPLGELVQWSDILSALFTMGHEL 162
XP_001629644  85 R-MWPLW----INGLESLLGKnHPVEEHPVKK--IFLYMGSFANNPA--WFRQAFSGAPLGELVQWSDVIACLTILGHQV 155
XP_001641454 247 Q-MWPQW----LSALEDLKKK-RDLKKIKQKK--ILVHIGLLANERALHFAANADKGGPLGELVQWSDLIASLYLLGHDV 318
Q9NDH7       162 R-LWKKW----KEGAHEVMQK-YPKSMIERRKlnVLVFIGFLANEQKLNMAKKSDHGGPLGELLQWSDLLATLSVIGHHL 235 Caenorhabditis ...
CAP31593     162 R-LWKKW----KEGAHEVMET-YEKTMTNRKKlnVLVFIGFLANEQKLKLAKKSDHGGPLGELLQWSDLLASLSIIGHHL 235
5ZIB_A       201 RISASLAELKEI-MKk-VVGNRSGCP-TVGDRI-VELIYIDIVGLAQFKKTLGPSWVHYQCMLRVLDSFGTEPEFNHANY 276
8_pfamImport 145 KVTNSVEQLTEL-FTpfLSSASSNCP-IQAKP--YDILYTDISGLKFLKHVAGNKFHLLQCEIRVVDSFGTEPEFNHAVY 220
XP_009859453 319 KVTNSMEQLGEL-FApyLTSASSNCP-LQSKP--YDILYTDISGLRLLKQVAGNKFHLLQCEIRVVDSFGTEPEFNHASY 394
XP_014325082 336 HLSASLPSLNKF-FG----IQTGGCP-SRLSLVePNLIYTDIIGLRQIQKVLKTSWIKYKCIIRVLDSFGTEPDFNHADW 409
CAF91608     177 HLSASLNDLLIL-LG----MKKSSCP--TISVVePDLIYTDILGLNQMQKAIPHIRSKYQCKIRVLDSFGTEPDFNHKAW 249
ESN93534     163 IVTSEYEELVGLvLC--VCVCVCVCV-IFIFRSvFFLCFF-TSSLYLLSFVFSASWFVCFCLLRIIDTFGTEAPYNSLTY 238
XP_001629644 156 VISTRKEELRES--TkqVLGQPSSCP-SKRREDeYDLVFTDYVGLAFMQKELGPNFSQYRCRLRILDSFGTEAQFNYFNP 232
XP_001641454 319 TVTADIPRLQGI-FGklRGPAKKPCP-TTIKND-YDLIYLDYYGVKQMQTKVGQFTQSFKCKFRIVDSFGTEAQFNYAGF 395
Q9NDH7       236 EVSTNKNTLRNI-VW--KYMSRGPCQyVNNFRQqLDIIFTDIMGFNILRQHHRQFLLSNRCRIRLLDSFGTHAEFTTKTY 312 Caenorhabditis ...
CAP31593     236 EVTTDKDSLRSV-LW--KYKERGPCQyVNGTRQqMDTIFTDIMGLNILRQYHRQFLLNNRCRIRLLDSFGTHAEFTTKTY 312
5ZIB_A       277 AQSK--------GHKTPWGKWNLNPQQFYTMFPHTPDNSFLGFVVEQHlNSSDIHHINEIKRQNQ----SLVYGKVDSFW 344
8_pfamImport 221 AGRK--------QHSSQWGKWNFNPKQFNTMFPHTPDNTFLGFVIEKHi---NSTLAATYKKENI----SLVYGKLDTFW 285
XP_009859453 395 AERK--------RRSTQWGKWNFHPKQFNTMFPHTPDNTFLGFVIEQHn---TVSIDSNNNKENI----SLVYGKKDSFW 459
XP_014325082 410 AKKY--------NLKSPFGGLSLAPMQFYTMFPHTPDNTFLGFVVQHQlSLEENEKLKSTQRKNQ----ALIYGKSATFW 477
CAF91608     250 AEVH--------NLSSSYGSLNLIPMQFYTMFPHTPDNTFLGFVVQPHwGDEESKRLKSIKRKKQ----ALVYGKRASFW 317
ESN93534     239 SKKFk-------NLKTAWGGQELDLRQFYTMFPHSPDNSFMGFVVEQHl---NTTESRSIERKQQ----ALVYGKSLYMW 304
XP_001629644 233 DRPIt-------KKTSSWGHQNLHLQQFMTMFPHTQDNTFLGFVVEAPtNITKPVLDPPPGKKPI----GLVYGKDSRFW 301
XP_001641454 396 TEKVp------gGSMALWGRHNLNLKQFMTMFPHSPDNSFLGFVV----GEEPTPDPHPKKKKAR----ALVYGKHYYMW 461
Q9NDH7       313 FVQNkkslsgpfSQRNPWGGHGLDLRQHWTFYPHSDDNTFLGFVV-------DTEGID--KKNNQmipsALVYGKEQYMW 383 Caenorhabditis ...
CAP31593     313 FLQNkrklsgpfSQRNPWGGHGLDLRQHWTFYPHSDDNTFLGFVV-------DTEGVD-EKRQKTlypsALVYGKEKYMW 384
5ZIB_A       345 k--NKKIYLDIIHTYMEVHATV------Y--GSSTKNIPSYVKNHGILSGRDLQFLLRETKLFVGLGFPYEGPAPLEAIA 414
8_pfamImport 286 q--GKEEYINAIHEVSPVHATVe-------tSEELNHVPPFVINHGVLPGFELHALLQRTKVFVGMGFPYEGPAPLEAIA 356
XP_009859453 460 e--GSEAYIEAIHKLSSVHGTVd-------aSNELQHVPAFVENHGVLPGIQLHSLLRKTKVFVGMGFPYEGPAPLEAIA 530
XP_014325082 478 k--GKKSYLDVIHKYLDIHGTV----------DNDTLIPNYVINHGIIKGTDVQTLLRQSKVFVGLSFPYEGPAPLEALA 545
CAF91608     318 e--GKTAYLDTIHKYLDLHGTV----------DKSASIPAYVTNHGIVKGAEVHALLRESKVFVGLSFPYEGPAPLEALA 385
ESN93534     305 s--GMQDYLSVISKHVEIHATV------FtnSNEAHLLPSFVHNHGILSGPDLHRLLSESKLFIGMGFPYEGPAPLEAIA 376
XP_001629644 302 l--GKDNYLKVLAKHLELHGTVv--------GSRMAAVPKSIKNHRIMNGRDYQAFLRSVKVYVGLGFPYDGPAPLEAIA 371
XP_001641454 462 kdlKQRSFLDVINKYMEIHATVg--------GGIKKWVPSYVINHGVLPSLEVQKLLQDSMIFVGLGFPYEGPAPLEAIA 533
Q9NDH7       384 r--DAEKPIDVLKRIVTVHSTVad---lDlkDSNISSIFKKVQNHGFLNSEEISQLLDNITIFFGLGFPLEGPAPLEAMA 458 Caenorhabditis ...
CAP31593     385 e--NAEKPIGVLKKFVKIHATVadledvNekKTNQSTVFDDVKNHGFLNSQEISELLDTTTIFFGLGFPLEGPAPLEAMA 462
5ZIB_A       415 NGCAFLNPKFN--PPKSSKNTDFFIGKPTLRELTSQHPYAEVFIGRPHVWTVDLNNQEEVEDAVKAILN---Q-KIEPYM 488
8_pfamImport 357 NGAVYLNVRFSksSPLYEKAASFFKGKPTSRKLTSQHPYTSTFIGYPHVRDVDIDNLDSIKKVITEIFE---SpEVEPYM 433
XP_009859453 531 NGAVFLNVIFKegSPSYVKATNFFKGKPTSRQLTSQHPYTSSFIGRPHVYDVDKDNMEEVKEILTEIFN---RpNVEPYM 607
XP_014325082 546 NGCAFLNPRLK--PPHSSLNTEFFKGKPTIREVTSQHPYAEE-IGEPYVWMVDMDNQTDVERAITAILN---R-TIKPYL 618
CAF91608     386 NGCIFLNPRLK--PPQSSLNSEFFKEKPNIREVTSQHPYAEA-IGEPYVWMVDMDNLTDVERAVRGIIN---Q-TIEPYV 458
ESN93534     377 AGCVFINPKFN--PPHSSLNTKFFKGKPTARELTSQHPYTEHFISNPNVFTVDISNLKEVERVVKQALQlidTnKVKPYL 454
XP_001629644 372 QGSVFLNAKLD--PPHSRDNTAFFKEKPTARKLSSQHPYAEEFIGKPYVYTVDISNMDEVEGAIKEILT---T-KVKPYI 445
XP_001641454 534 HGCFFLNTKYH--PPRNRINTPFFKDKPTLRQITSQHPYAEDYIGQPYVYTVDINDLNKIEAVMKEIMM---AePVSPYL 608
Q9NDH7       459 HGAVFINAKFK--EPKSRLNYKFLAEKPTLRKWTSQNPYME-KIGEPHVITVDIFNELELEEAIKRAIS---L-KPKHFV 531 Caenorhabditis ...
CAP31593     463 RGAVFINARFE--IPKSRKNYKFLAEKPTLREWTSQNPYME-EIGEPHVITVDINNEKELEIAIKRAIE---L-KPKPFV 535
5ZIB_A       489 PYEFTCEGMLQRINAFIEKQDFC---HGQVmWPPLSALQVKLA-EPGQSCKQVCQESQLICEPSFFQHLNKDKDMLKYKV 564
8_pfamImport 434 PYEFTCLGMLERLGLLVEKQDFCq-gDESPiWPPVAALQTVQT-DDQQSCMEACTLKGLICEPAYFPYINLHTHFAKEGI 511
XP_009859453 608 PYEFTCLGMLERLGLLVEKQDFCt-sDATPtWPPITSLKTVET-TGRQTCVEACAAQEMICEPAYFPYINLRTHFEQQGI 685
XP_014325082 619 PYEFACEGMLQRVNVLIEKQDLC---SPAIiWPPLSSLQVVKA-EAGTSCKQACWRAGLICEPAFFPYLNNANNLASHNI 694
CAF91608     459 PYEFTCEGMLQRVNILIEKQDFC---PNATrWPPLSALQVVRA-DRNASCKSACQKQGLICEPTFFPHLNNAQSLAGYGI 534
ESN93534     455 PFEFTHKGMLQRLNAYMEHQDFCt--PHKNiWPPVRAVRLLVS-ESGQSCKDACWSRNMTCEPSHFRRINKPQTFEHLFS 531
XP_001629644 446 PFEWTTQGMLERVNALVNNQNFC---DHTSrWPPIEELKLIQG-LETESCTQTCKAKGLLCDPAFFPDINISKSFQTLGI 521
XP_001641454 609 PYEFTHKGMLERLHVFIENQNFC----GQNlWPPLNALQARKG-AMGSSCKETCHSLGLVCEPQYFPAINTKERMTRSGF 683
Q9NDH7       532 PFEFTPAGMLHRVALLLEKQELCdkiAYSKrWPPIDQMKIFRTlNADDSCETICHSKQLLCEPSYFPIINSSPLL-RREN 610 Caenorhabditis ...
CAP31593     536 PFEFSPAGMLLRVALLLEKQETCgkiAKSKrWPPVNQMKIFKTvNSGDSCEMTCHSQKMKCESSYFPIINSPSLL-QRQF 614
5ZIB_A       565 TC------QSSELAKDIL-VPSFDPKNKHCVFQGDLLLFSCAGAHP---RHQRVCPC 611
8_pfamImport 512 TCdtfkvpDGTKVEID---FPAHAD--GTCYIQSDPLLYSCAGRYT---TLLHICPC 560
XP_009859453 686 KCdqfkapEGAETEID---YPAHAD--GICYIQSDKLLFSCAGRYT---NLHHICPC 734
XP_014325082 695 AC------QTSEFSDGHLvFPAYDSTEDHCLFQSDSLLYSCVRSEQ---SLNRICPC 742
CAF91608     535 DC------QSTERSDDHLvLPAYDSSIQHCLFQSDPLLFSCVRSHP---SWTRVCPC 582
ESN93534     532 SSssaarpYTGEAELHH---PSVSEKLGTCYLQGDNLLFSCVSRTE---GYLRVCPC 582
XP_001629644 522 KC-------SSEMSKDSLhAPSYSTIDDSCLLQRSALLFSCGDSSP---IYRRVCPC 568
XP_001641454 684 PCn-----TTRVEDMPSLvAPGYRDDPPVCLRQAQNLLFSCTANSP---TTKRLCPC 732
Q9NDH7       611 LC------SSTTSDSSPF-APF------NCTIQQSAFLFSCASSPPisfEINRLCPC 654 Caenorhabditis elegans
CAP31593     615 GC------SSTIPDASPF-APF------NCTVQSSAYLFSCASRPPl--EVVRVCPC 656
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap