Conserved Protein Domain Family
FAM194

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pfam14977: FAM194 
FAM194 protein
This family is found in eukaryotes, and is approximately 210 amino acids in length. There is a conserved YPSG sequence motif. The function of this family is unknown.
Statistics
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PSSM-Id: 464417
Aligned: 29 rows
Threshold Bit Score: 183.262
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EEN69686      443 KIPRMDSPVEQGRLKlMRQLPDGSCSV--FYPSGRVAISISPPTKPGQlgLYtnVYADNL---QGTMLASFTPSGHGCCY 517 
CBJ29876        9 TKADNAEYYPSGRLA-SVFKEDGSGFI--YYPSGLVAVCKGVVDGRGR--YY--VYGDDR---RSTPLGAVNEHGVGFFL 78  
XP_007500331  393 SQSLETK-WKRAFRF-HYSFYDGTTFV--FYPSGHVAVSQIPTCCKGR--YTtcIFNDTS---NFPIIGLFTAEGHGSVN 463 
XP_009443214  359 QHCQEGKAPKKAFKF-HYTFYDGSSFV--YYPSGNVAVCQIPTCCRGR--TItcLFNDIP---GFSLLALFNTEGQGCVH 430 
XP_023605387  346 QQSQECKGGKKNIKL-HYTFCDGSSFV--YYPSGNIAMCQIPTCCGGR--TItlLFNDTP---NFSFLALFNAEGQGFVH 417 
XP_003796316  346 RQSQEWKMSRKTFKL-HYTFFDGSSFV--YYPSGNIAMCQIPTCCRGR--NItcLFSDT----SAAFLALFNGEGQGCVH 416 
XP_021587644  355 RHSQEWKVPKKSAKL-HYSFYDGSSFV---YPSGNVAMCQIPTCCRAR--AVtcLFSDTP---NFTFLALFSAEGHGYVH 425 
XP_023417900  352 RHSQDLKVSKKAAKL-HYSFQDGSSFV---YPSGNIAICQIPTCCKAR--AItfLFNDTP---SYSFLALFNAEGQGCVQ 422 
XP_008258601  362 RNPQKQKVPKKPIKL-HYTFYDGSSFV--YYPSGNIAVCQIPTCCRER--TItyLYNDVP----HSFLALFIADSQGYVH 432 
XP_002116284  670 NQLPIQKFYENGSLF-LILLPDGTGSVlyLYNSCNVAIGISA--HGNG--LSyvVLEDAPlseSQKILALFNPSGHSCIY 744 
EEN69686      518 HPNGv---PRFVMSPEGGMLMEPDGTISKQWSW------------PKTGKLPVTvNVQVTELLVLRCTNLSSVALHFACQ 582 
CBJ29876       79 GPSG----VRLALSKVGGLITDRHGYIAREWRYdp---------gAHMPPPTSVlDVKLNKSMNFEFLDRREMRIKFLHE 145 
XP_007500331  464 YNLKnrcpCMFMMNHEGGSIKDSSGHTVHKWNWt-----------SKKRTLLSL-EYKMNEQIKLRVFGQDCITLTFSDL 531 
XP_009443214  431 YNLKtscpYVLILDEEGGTTNDQQGYVVHKWSWt-----------SRTETLLSL-EYKVNEEMKLKVLGQDSITVTFTSL 498 
XP_023605387  418 YNLKsccpYVLVLDEEGGTTNDYKGYAVHKWSWa-----------SKTETLLSL-EYKMNEQMKLTVLGQDSILVTFTCM 485 
XP_003796316  417 YNLKtccpYVLVLDDEGGTTNDQKGYVVHKWNWt-----------SKTETLLSL-EYKVNEQMKLKVLGQDSIVVTFTSL 484 
XP_021587644  426 YNAKsrspYVLVFDDEGGTTNDHKGYIVHKWSWt-----------SKTETLLSL-EYKVNEQMKLTMLGQDSVVVTFTSL 493 
XP_023417900  423 YNLKthcpYVLVLDEEGGTTNDHKGYVVHKWSWt-----------SKTETLLSL-EYKVNEQLKLKVLGQDSIVVTFTSL 490 
XP_008258601  433 YNAKtrcpYVLVLDEEGGTTTDHKGYIVHKWSWs-----------SKTETLLSL-QYKVNEQLKLTVLGKDCITVTFTSL 500 
XP_002116284  745 HSNNr---IRLLIYPTGGEVADSNGTRKKKWNWdldshldknnahIHAPPFQPI-CFAITKEVALRCKWQDKVYLSFSAQ 820 
EEN69686      583 KETAKFNVGLYAgavqpkveemgylktegpfisqaakesvkpkkkEKDRLRrg----fIKPKEKRVSQQMAELTKILELP 658 
CBJ29876      146 GISHELDAGVHP---------------------------------KREGTYldnrqqaFGNAMKAKRDRLKPRSRNLAGA 192 
XP_007500331  532 NESVSLVISPTDcphgvprekrys---------frssteertskmIRA----------LVEIKKRFQKTVTQFMNSVLLL 592 
XP_009443214  499 NETVTLTVSANNcphgmaydkrlnr--------risnmddkvykmSRA----------LAEIKKRFQKTVTQFINSILLA 560 
XP_023605387  486 NETVTLTISANNcphgvghdkkmih--------kttsmddklskmSRA----------LAAIKRRFQKTVSQFMNSVLLA 547 
XP_003796316  485 NETVTVPITANNcphrmshekrlpr--------gissidekvskmSRA----------LAEIKKRFQKTVTQFMNSVLLA 546 
XP_021587644  494 NETVALTVSARTcphgtmpekwlsr--------rlggsddkvsklTRA----------LAEIKRRFQKTVTQFMNSILLA 555 
XP_023417900  491 NETVMITVSARNcphgmaqekrms---------rristdekiskmSRA----------LAEIKKRFQKTVTQFMNSVLLA 551 
XP_008258601  501 NETVTLTVSSKNcphrplhskrpsr--------risvmedkiskmSRA----------LAELKKWFQKTLTLLMNSILLA 562 
XP_002116284  821 ARSCKFNVGVKLklihpq----------------------qtpelSKAQKMeleneefLNNAKKRIRKLLNKTQTTLRYP 878 
EEN69686      659 GDKDEFFS 666 
CBJ29876      193 CKSLVASL 200 
XP_007500331  593 AGLLTIDY 600 
XP_009443214  561 AGLFTIEY 568 
XP_023605387  548 AGLLIIEY 555 
XP_003796316  547 SGLLTIEY 554 
XP_021587644  556 AGLFTIEY 563 
XP_023417900  552 AGLFTIKY 559 
XP_008258601  563 AD-----L 565 
XP_002116284  879 KSPRLEQL 886 
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