Conserved Protein Domain Family
DUF2371

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pfam10177: DUF2371 
Uncharacterized conserved protein (DUF2371)
This is a family of proteins conserved from nematodes to humans. The function is not known.
Statistics
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PSSM-Id: 462979
Aligned: 17 rows
Threshold Bit Score: 185.219
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_010857422  14 KQDPLRPPGQV-----------PKRKRKTKKRRKNDVVVVKGKLKLCSVSGLIALCGIVVLLVGIALAVVGYWPKANGAH 82 
4_pfamImport   1 RQDSARSQHRPpsaap-gpggsAPESAPRKRKRRTDVVVVRGRLRLYSASGFFLLLGLVILAAGIAMATLGYWPHRAPPA 79 
XP_005449742  16 RQDSARSQHRPvpptspglghaAPEAAPRKRKRRTDVVVVRGRLRLYSASGFFLLLGLIILAIGIGMATLGYWPHSKAML 95 
Q5RGQ8        16 RQDSTRSQYHLsaqs----pgpAPEKKTTKRKPRADVVVVRGKIRLYSASGFFLVLGVLILMAGIAMAVLGYWPHKDQPK 91  zebrafish
XP_015213874  16 RQDSARSQHHLplpt----pppPQEKKRVKRKPRADVVVVRGKIRLYSPSGFFLILGIFISMVGIAMAVLGYWPHKDQVL 91 
XP_003769479  16 RQDSARSQHHVnlsp----spaDQEKKPVRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIIGIAMAVLGYWPQKEHFI 91 
XP_005043612  16 RQDSARSQQHVnlag----vpvPEEKKPVRRRPRTDVVIVRGKIRLYSPSGFFLVLGVLIAFFGIAMAILGYWPQKEQLL 91 
XP_008116308  16 RQDSARSQQHLnltt----spaNEEQKPVKRRPRADVVVVRGKIRLYSPSGFFLVLGVLVSFLGIGMAILGYWPHKDLYA 91 
XP_006634030  14 RQDSLRSKNRAq----------NKRKRKPKKKRKNDVVVVKGKLKLCSVSGLIAAIGILVLLVGIAMAIMGYWPRNSPVY 83  spotted gar
XP_014346726  14 KQDSFRSRNHV-----------NKRKRKAKKKRKNDVVVVKGKIKLCSISGLVAAFGILVLLVGIAMAVMGYWPKTNHQL 82  coelacanth
XP_010857422  83 regakqpppppgdsgprvpsvtsssggnrnrsrtqpgppegvtASSVgaprstpPARSPAPSPSSSTSVGFFFRVFSGYL 162
4_pfamImport  80 r-----------------------------------------vTTCE-------VSERRSTGTISKRTAGALTRFLEQHR 111
XP_005449742  96 ag----------------------------------------gGTGVktekdaaNASHNGQGTPSRETESALMRFLEQHL 135
Q5RGQ8        92 -------------------------------------------APET-------KMSANNTQSFGREQAGSIAQFLEQHM 121 zebrafish
XP_015213874  92 -------------------------------------------TPDS-------KLSTNDTQVI-RDHGGIVAQFFEQHL 120
XP_003769479  92 -------------------------------------------DAET-------KLSTNQTQVI-RNQGGIMVRFFEQHL 120
XP_005043612  92 -------------------------------------------GSEA-------NPSVNETRTP-RSQGSILLRFFEQHV 120
XP_008116308  92 -------------------------------------------ESED-------ILSLNETQGI-GKESGIIIRFLEQHL 120
XP_006634030  84 qdvrqsknspnnrktvl----------esnnqtsnrhiyqtdrDSLK-------NNHSNSTSVDTSSSLGFFAEFLERYL 146 spotted gar
XP_014346726  83 e--------------------------------------------IT-------KTNNSNTNKVKNSPLSLLAELLASYL 111 coelacanth
XP_010857422 163 HSDKLKVFGPLIMGIGIFLFICANAVLHENRDKETKIINLR 203
4_pfamImport 112 HSERMKMFGPFTMGIGIFIFICANAILHENRDRETKIIHMR 152
XP_005449742 136 HSERMKMLGPFTMGIGIFIFICANAILHENRDRETKIIHMR 176
Q5RGQ8       122 HSEKMKMLGPFTMGIGIFIFICANAILHENRDRETKVIHMR 162 zebrafish
XP_015213874 121 HSEKMKMLGPFTMGIGIFIFICANAILHENRDKETKVIHMR 161
XP_003769479 121 HSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMR 161
XP_005043612 121 HSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMR 161
XP_008116308 121 HSDKMKMLGPFTMGIGIFIFICANAMLHENRDKETKIIHMR 161
XP_006634030 147 YSDKLKVFGPLIMGIGIFLFICANAVLHENRDKKTKIINLR 187 spotted gar
XP_014346726 112 YSDKFKVLGPLIMGIGIFLFICANAVLHENRDKKTKIINLR 152 coelacanth
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