3ZNC,5IPZ,3FE4,1DMY


Conserved Protein Domain Family
Carb_anhydrase

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pfam00194: Carb_anhydrase 
Eukaryotic-type carbonic anhydrase
Statistics
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PSSM-Id: 459707
Aligned: 302 rows
Threshold Bit Score: 108.123
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3ZNC_A         15 LGPEKWp---G-AC-KENQQSPINI-VTARTKVNPrLT---PFILv-GYDQKQQw----pIKN-NQHTVEMTLG------ 73  house mouse
EFN58863       11 EGGSDW----PgVCaDGSHQSPIGI-VTGSELAPA-LPpeaRASL--NFGVALGl----rIFN-TGRTVQVEWDdldgsn 77 
XP_005990291    7 GPSTWKdtvsT-CG-GQNQSPVDLD-RQNMQRNKSlGR---FTFRg-YNIVPPGkw--kvVNN-GHAVQVNVEGnti--- 73 
13_pfamImport   1 LGPADWkesyS-AC-GGTHQSPINI-PMRELSHDDw----gMDHAplKYGGNCEkfslkkLE--DLYK------------ 59 
XP_002898880   36 LGPADWkgsyS-AC-GGTHQSPINI-PMRKLSHNDw----gMAHAplKFGGDCSkfslkkLE--DLYK------------ 94 
EWS74936       26 SGGSDWt---G-TCsTGQSQSPIDI-SNIQGTCDN------SMTIdv------------sLYNqNVQT-SVV-------- 73 
A0BL70         51 ANVANWad-lVvTC-GGSFQSPIDI-VTTGSTQEPvqp-------qiHYRSKDAsvg-yeEAN-KPYT-----Keyeg-- 111 Paramecium tet...
XP_001868681   27 LGVEQWgmisK-YC-DGQRQSPIDL-DTSIAKNVTePK---RLQLv-NAAVNPTkv---tVKN-NGITVAFALTyp---- 91 
XP_001847385   59 ESIQEWgdisP-FC-NGKLQSPIAL-YTKSSMPVAnVP---PLFLs-GSRQNPKkv---tVQN-TGKTVMYEFEf----- 122
EDS26117      101 FGPSNWga-lNsNC-NGLYQSPIDLvTNRTLVVRQk----rPLRLd-GLSNRPWqm---dVEN-EGGSAAFFPEyr---- 165
3ZNC_A         74 ------GG--ACIIG-------GDL-P-A------RYEAVQLHLHWSngndNGSEHSIDGRHFAMEMHIVHKKLts---- 126 house mouse
EFN58863       78 asvpilGTgwASIYDpaa-lysTPTgPpPkl---fQIPFKPFQIHWH----SACEHVMDGDACPLELHIVTAVD------ 143
XP_005990291   74 ----mgYI--NISGA-------GLP-N-T------FRALQFHFHWGNatqnGSEHTLDKEQYPMELHIVHINAKyn---- 128
13_pfamImport  60 ----------WEIHGdehctvkSINfDeR------EYGLAQFHVH------STSEHALDEYHYDAEIHFVHKDV------ 111
XP_002898880   95 ----------WEIKGdehctvkSINfDeR------EYGLAQFHMH------ATSEHALDDYHYDAEIHFVHKAV------ 146
EWS74936       74 ----------KDQSGlssagdfGSLyAkDingilvGYEANQIQVH------IPSEHSIDGSGYDIELQIYFSIKkefqat 137
A0BL70        112 ---eysEIevTDASG-------SVI----------RYYAKQFHIH------TPSEHTIDGKYYDLEIHFVHQAI------ 159 Paramecium tet...
XP_001868681   92 ----psKQ--LVLRG-------GPLeG--------EFKFAGLHFHW------GCEHSEDHQRHPMEMHLVFYNQdy---- 140
XP_001847385  123 -----lRP--IIARG-------AALdG--------EFQFNHIHFHWGstsdKGAEHEVNGQRFPLEMHLVFFNKiy---- 176
EDS26117      166 ----asER--PRLSG-------GPLkT--------DYLFQQFHYH------LGSEHTFEGKRYAAEAHFVFFNSly---- 214
3ZNC_A        127 --skE----D--SK-D---KFAVLAFMIEVGDK-Vn--kG-----FQPL--VEALPs------iSKPH--STSTVR---E 173 house mouse
EFN58863      144 ----NstgaEvpEPcNaapCLAVFGVLLKYNPDvY----ApgapyLDTI--LSNVP--------DTVGaaAATHLPg-aT 204
XP_005990291  129 --kiIdakkD--PN-G---LAVLGFFYQNNDAS-Ns--nY-----NTIV--ASLKNv------sYKGD--EVDLAS---T 179
13_pfamImport 112 ---------------NgsgKILVTGVFLNAQKDvEes------sfIKNL--WNDLDtdgetfnlQDSGlnYA-------- 160
XP_002898880  147 ---------------DgsgKILVTGVFLNAEPKvQen------afVKGL--WKDLEteessfnlRDAGmtYA-------- 195
EWS74936      138 lsgqTpavlN-----N-----AVVSIFYTIDSTqSs--------nFFNVwtPSSIG----------------TNFS---- 179
A0BL70        160 ----QdseqDcnTVkN---KLTVFGLMFQESSSaTdydaFkpwfdSNTTgeVESFD------------------------ 208 Paramecium tet...
XP_001868681  141 --ktVdeaqF--QE-N---GLAVLGYFFA--NStKa--------kNQRW--IDSLQs------iKKTG--SSYTFVhpqY 192
XP_001847385  177 --gtIekamP--SP-N---GLAVIGVLFQ--IDeRs--nV-----TYPW--LTPMAn------vRLAG--TTYKLPnptA 229
EDS26117      215 --etFgearG--QV-D---GIAVIAVVYDVLKSdRik-------sLNNW--TRFLTk------vVKDG--SVYEVSpygL 269
3ZNC_A        174 S-SL----QDMLPpstkMY-TYFRYNGSLTTPNCDETVIWTVYKQPIK-IHKNQFLEFSKNLYYDEDqk----------- 235 house mouse
EFN58863      205 L-DL----SSLLP----EDlTYVAYNGSLTTPPCSESVAWHVFVTPKAeLSASQVQGLQAILGTTVEeapaacvvnggap 275
XP_005990291  180 FrLD----SLLPPvqklSR-YYRYRGSLTTPDCKEAVIWTVFEEPIQI-SQSQYNEFVNTVFFSARGete---------- 243
13_pfamImport 161 ---------QMLNgl-vAKsHLFNYNGSLTTPPCSEVVDWWVLNNPIP-ISYDELHKLKTLYNELPStn----------- 218
XP_002898880  196 ---------EMLNgl-vAKsHVFNYNGSLTTPPCSEVVDWWVLNNPIS-ISYDELHQLKKVYGELPAtn----------- 253
EWS74936      180 F-NP----ATVFNgtidstnQYYSYQGSLTQPGCDESVNWYIFPQSQP-ISQIQYNDIKKYIQGDLTfag---------- 243
A0BL70        209 ---LndffSKL------SDaTYYHYNGSLTTLPCSQTVNWVVFQQPLP-ISTAQLKQFQDYLADSTLf------------ 266 Paramecium tet...
XP_001868681  193 M-NI----AKLVGs--dLR-PYFSYDGSLTTPPCYETVTWLVHREPLL-ITNKQLKLFQSLRGKFG-------------- 249
XP_001847385  230 F-NV----DALIGs--tRT-HYFSYKGSLTNPPCYETVTWMVMRKRLP-VREDQLATFRALLQSYGQ------------- 287
EDS26117      270 F-PL----GDVLGs---VQwPYYAYEGSFTTPPCAETVQWIVASERVP-LTKSELVRMRNLEGRGG-------------- 326
3ZNC_A        236 -lNM----KDNVRPlqplGkRQVFKSH 257 house mouse
EFN58863      276 hsQLtcriPSGARI----NnRVLQPVG 298
XP_005990291  244 mrMQ----NNFRPPlplnKrKVYASKD 266
13_pfamImport 219 -------dASDNRPtqplNdRQIKYY- 237
XP_002898880  254 -------dASDNRPtqplDdREIKYY- 272
EWS74936      244 -------ghgNNRNiqsvNgRTIKLGN 263
A0BL70        267 --PI----KHNNRPiqhlNgRKILKGT 287 Paramecium tetraurelia
XP_001868681  250 --YM----RDNYRPiqtlNdREITLYH 270
XP_001847385  288 --PL----VNNHRPlrdlNgRRVLLFR 308
EDS26117      327 --RW----VQNARPtqarNyRRVFIY- 346
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