Conserved Protein Domain Family
CASP_dom

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pfam04535: CASP_dom 
Casparian strip membrane protein domain
This domain is found mainly in plant proteins known as Casparian strip membrane proteins (CASPs) and CASP-like proteins (CASPLs). CASPs are four-membrane-span proteins that mediate the deposition of Casparian strips in the endodermis by recruiting the lignin polymerization machinery. Interestingly, the CASP first extracellular loop was found conserved in euphyllophytes but absent in plants lacking Casparian strips.
Statistics
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PSSM-Id: 367980
Aligned: 84 rows
Threshold Bit Score: 32.2869
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6YT98              33 PAKCSGANLALRALLFAVSLSALVVLVTAKQTVMVPfvirp----pqfiLAPVPAKYTHSPALIYLLAALCATCFYSLIT 108 Japanese ...
WGS:AAAA:OsI_27431  48 DDGLDGIVLVLRAAAALLALVAMALVASCRHG--------------------DWMEFTRYQEYRYLLGVAVVASLYSALQ 107
WGS:AAAA:OsI_11172  55 EDMLDKSPLALHAAAAAFAFVALVLVASNQHG--------------------DWMEFDRYQEYRYLLAIAALAFAYSLAQ 114
O24088              61 EVKWYVALLVIRVFAFVFCLIAFSVLGASEQRVLVSenltnwyssgftiQTPYEFHWYKWDEFRYSFAANVIGFVYSGLQ 140 barrel medic
Q501G6             143 DDLVSLTALGFRITEVILCVISFSIMAADKT------------------QGWSGDSYDRYKEYRYCLAVNVIAFVYSAFE 204 thale cress
Q84WP5             129 EEVVKFSALGFRLSEVVLALISFSIMAADKT------------------KGWSGDSFDRYKEYRFCLSVNVVAFVYSSFQ 190 thale cress
Q0JKN7             252 RSELRRAELGFRVLAAVFCLVSLSVMAADTT------------------PGWSGDSFRRYNEYRYTLSASVLAFTYSGFQ 313 Japanese ...
WGS:AACV:OsJ_02779 198 VGERRTTSVALRVATAVLSLVSFALMVSART------------------SGWAGDHYGRYEQYRYAVGVNIVVCIYSIAQ 259
Q9FNE8             116 ASLIRKALLGFRVIAFVSCLVSFSVMVSDRD------------------KGWAHDSFYNYKEFRFCLAANVIGFVYSGFM 177 thale cress
CAN71455           551 ERAVERAALGFRVCGFLFCLVSFSIMASDKN------------------QGWTLDSFDRYKEFRCILSGS---------- 602
Q6YT98             109 AISSVRLLSs-----sACSAKTLFYLILLDVFYAAVMASATGTAGAVAWVGLKGnshtrwnKICNVYGKFCRHIGSSTFL 183 Japanese ...
WGS:AAAA:OsI_27431 108 AARTFRRMRagtayaaT------FLDFAGDQAVGYLLITASSAALPITIRMRSA-----------VVNTFTDVVAASISF 170
WGS:AAAA:OsI_11172 115 ALRHALRMRrgvdpvpTAS--GRLLDFASDQVVAYLLMSALSAATPITNRMRSA-----------VINRFTDTTAAAISM 181
O24088             141 ICHLVMYLItkkhtinPKL--QGYFNVAIDQTLAYILMSASSSAATAAHLLKDY-------WLEHGADTFIEMANASVSM 211 barrel medic
Q501G6             205 ACDAACYIAkesyminCGF--HDLFVFSMDQLLAYLLMSASSCAATRVDDWVSN----------WGKDEFTQMATASIAV 272 thale cress
Q84WP5             191 ACDLAYHLVkekhlisHHL--RPLFEFIIDQVLAYLLMSASTAAVTRVDDWVSN----------WGKDEFTEMASASIAM 258 thale cress
Q0JKN7             314 LVVEVHYFVtgrriirDPS--GKYFNLAMDQILAYLLLSASSAALSRNDVWVSR----------FGVDQFAKLINASASM 381 Japanese ...
WGS:AACV:OsJ_02779 260 AFGEIRRL-----------------------VLAYLLMSASSAAASRNDLWMSS----------FGKDPFNKKINSAVWF 306
Q9FNE8             178 ICDLVYLLStsirrsrHNL--RHFLEFGLDQMLAYLLASASTSASIRVDDWQSN----------WGADKFPDLARASVAL 245 thale cress
CAN71455           603 ECDRVCVLRparmrlsLPFXYRTACSPAPPPVLTYLLISASSSAATRVEDWQSN----------WGKDKFPEMARASVWM 672
Q6YT98             184 ALIAAIV 190 Japanese rice
WGS:AAAA:OsI_27431 171 AFLAFAA 177
WGS:AAAA:OsI_11172 182 AFLAFVS 188
O24088             212 SFLAFGA 218 barrel medic
Q501G6             273 SFLAFGA 279 thale cress
Q84WP5             259 SFLAFLA 265 thale cress
Q0JKN7             382 AFLAFVA 388 Japanese rice
WGS:AACV:OsJ_02779 307 SFIAFIG 313
Q9FNE8             246 SYVSFVA 252 thale cress
CAN71455           673 SFLAFVA 679
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