3UJG


Conserved Protein Domain Family
STKc_SnRK2

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cd14662: STKc_SnRK2 
Click on image for an interactive view with Cn3D
Catalytic domain of the Serine/Threonine Kinases, Sucrose nonfermenting 1-related protein kinase subfamily 2
STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. The SnRKs form three different subfamilies designated SnRK1-3. SnRK2 is represented in this cd. SnRK2s are involved in plant response to abiotic stresses and abscisic acid (ABA)-dependent plant development. The SnRK2s subfamily is in turn classed into three subgroups, all 3 of which are represented in this CD. Group 1 comprises kinases not activated by ABA, group 2 - kinases not activated or activated very weakly by ABA (depending on plant species), and group 3 - kinases strongly activated by ABA. The SnRKs belong to a larger superfamily that includes the catalytic domains of other STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.
Statistics
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PSSM-Id: 271132
Aligned: 18 rows
Threshold Bit Score: 545.905
Created: 7-Aug-2013
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Conserved site includes 18 residues -Click on image for an interactive view with Cn3D
Feature 1:ATP binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1            ####    #            # #                           #               ####  
3UJG_A     19 RYELVkdIGSGNFGVARLMRDKqsNELVAVKYIERgekideNVKREIINHRSLrHPNIVRFKEVILtpthLAIVMEYASg 98  thale cress
AFW71758    3 KYELLkdIGSGNFGVARLMRNKdtKELVAMKYIPRglkideNVAREIINHRSLrHHNIIRFKEVVLtpthLAIVMEYAAg 82  Zea mays
P0C5D6      4 RYEALkeLGAGNFGVARLVRDKrsKELVAVKYIERgkkideNVQREIINHRSLrHPNIIRFKEVCLtpthLAIVMEYAAg 83  Japanese rice
1168529     3 KYELVkdIGAGNFGVARLMKVKnsKELVAMKYIERgpkideNVAREIINHRSLrHPNIIRFKEVVLtpthLAIAMEYAAg 82  thale cress
O64812      3 KYEMVkdLGFGNFGLARLMRNKqtNELVAVKFIDRgykideNVAREIINHRALnHPNIVRFKEVVLtpthLGIVMEYAAg 82  thale cress
ACG50014    3 KYEAVrdIGSGNFGVARLMRNRetRELVAVKLIERghrideNVYREIVNHRSLrHPNIIQFIEVILtpthLAIVMEYAAg 82  Zea mays
BAD18000    3 KYEAVrdIGSGNFGVARLMRNRetRELVAVKCIERghrideNVYREIINHRSLrHPNIIRFKEVILtpthLMIVMEFAAg 82  Japanese rice
Q7XQP4      3 RYELLkdIGAGNFGVARLMRNKetKELVAMKYIPRglkideNVAREIINHRSLrHPNIIRFKEVVVtpthLAIVMEYAAg 82  Japanese rice
ACG50011    3 KHELLkdIGAGNFGVARLMRNKetKELVAMKYIPRgqkideNVAREIINHRSLrHPNIIRFKEVVLtpthLAIVMEYAAg 82  Zea mays
ABK25003    3 RFEVVkdIGSGNFGVARLMRNKktKELVAMKYIERgrkideNVAREIINHRSLrHPNIIRFKEVLLtpthLAIVMEYAAg 82  Sitka spruce
Feature 1      #                                          ## #           ##                   
3UJG_A     99 GELFERIcnagrfSEDEARFFFQQLISGVSYCHAMQVCHRDLKLENTLLDgspaPRLKICDFGYSKSSVLHsqpKSTVGT 178 thale cress
AFW71758   83 GELFDRIcsagrfSEDEARYFFQQLICGVSYCHFMQICHRDLKLENTLLDgspaPRLKICDFGYSKSSLLHskpKSTVGT 162 Zea mays
P0C5D6     84 GELFEQIctagrfSEDEARYFFQQLISGVSYCHSLEICHRDLKLENTLLDgsptPRVKICDFGYSKSALLHskpKSTVGT 163 Japanese rice
1168529    83 GELFERIcsagrfSEDEARYFFQQLISGVSYCHAMQICHRDLKLENTLLDgspaPRLKICDFGYSKSSLLHsrpKSTVGT 162 thale cress
O64812     83 GELFERIssvgrfSEAEARYFFQQLICGVHYLHALQICHRDLKLENTLLDgspaPRLKICDFGYSKSSVLHsnpKSTVGT 162 thale cress
ACG50014   83 GELFDRIvdrgrfSEDETRYFFQQLICGVSYCHHMQICHRDLKLENVLLDgspaPRLKICDFGYSKSSVLHsrpKSAVGT 162 Zea mays
BAD18000   83 GELFDRIcdrgrfSEDEARYFFQQLICGVSYCHHMQICHRDLKLENVLLDgspaPRLKICDFGYSKSSVLHsrpKSAVGT 162 Japanese rice
Q7XQP4     83 GELFDRIcnagrfSEDEARYFFQQLICGVSYCHFMQICHRDLKLENTLLDgspaPRLKICDFGYSKSSLLHskpKSTVGT 162 Japanese rice
ACG50011   83 GELFDRIcnagrfSEDEARYFFQQLICGVSYCHSMQICHRDLKLENTLLDgspaPRLKICDFGYSKSSLLHskpKSTVGT 162 Zea mays
ABK25003   83 GELFDRIcnagrfSEDEARFFFQQLISGVSYCHAMKICHRDLKLENTLLDgspaPRLKICDFGYSKSSVLHsrpKSTVGT 162 Sitka spruce
Feature 1                                                                                     
3UJG_A    179 PAYIAPEVLLkkeydGKVADVWSCGVTLYVMLVGAYPFedpeepknfrktihrilnvqyaipdyvhisPECRHLISRIFV 258 thale cress
AFW71758  163 PAYIAPEVLSrreydGKMADVWSCGVTLYVMLVGAYPFedpddpknfrktigrivsiqyqipeyvhisQDCRQLLARIFV 242 Zea mays
P0C5D6    164 PAYIAPEVLSrkeydGKVADVWSCGVTLYVMLVGSYPFedpgdprnfrktisrilgvqysipdyvrvsSDCRRLLSQIFV 243 Japanese rice
1168529   163 PAYIAPEVLSrreydGKMADVWSCGVTLYVMLVGAYPFedqedpknfrktiqkimavqykipdyvhisQDCKNLLSRIFV 242 thale cress
O64812    163 PAYIAPEVFCrseydGKSVDVWSCGVALYVMLVGAYPFedpkdprnfrktvqkimavnykipgyvhisEDCRKLLSRIFV 242 thale cress
ACG50014  163 PAYIAPEVLSrreydGKLADVWSCGVTLFVMLVGAYPFedqddpknirktiqriaaiqynipdnirisDDCRQLISRIFV 242 Zea mays
BAD18000  163 PAYIAPEVLSrreydGKLADVWSCGVTLYVMLVGAYPFedqddpknirktiqrimsvqykipdyvhisAECKQLIARIFV 242 Japanese rice
Q7XQP4    163 PAYIAPEVLSrreydGKTADVWSCGVTLYVMLVGAYPFedpddpknfrktigrimsiqykipeyvhvsQDCRQLLSRIFV 242 Japanese rice
ACG50011  163 PAYIAPEVLSrreydGKTADVWSCGVTLYVMLVGGYPFedpddpknfrktigrimsiqykipeyvhvsQDCKELLSRIFV 242 Zea mays
ABK25003  163 PAYIAPEVLSrkeydGKLADVWSCGVTLYVMLVGAYPFedqddpknfrktiqrimsvqytipdyvhvsPECKQLLGRIFV 242 Sitka spruce
Feature 1                      
3UJG_A    259 adPAKRISIPEIRNHEW 275 thale cress
AFW71758  243 anPAKRITIREIRNHPW 259 Zea mays
P0C5D6    244 adPSKRITIPEIKKHTW 260 Japanese rice
1168529   243 anSLKRITIAEIKKHSW 259 thale cress
O64812    243 anPLHRSTLKEIKSHAW 259 thale cress
ACG50014  243 snPLRRITMREIKSHPW 259 Zea mays
BAD18000  243 nnPLRRITMKEIKSHPW 259 Japanese rice
Q7XQP4    243 anPAKRITIREIRNHPW 259 Japanese rice
ACG50011  243 anSAKRITIREIRNHPW 259 Zea mays
ABK25003  243 anPHKRITIREIRHHPW 259 Sitka spruce

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