5SXG,2NBQ


Conserved Protein Domain Family
NAD2

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pfam18782: NAD2 
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Novel AID APOBEC clade 2
A distnct family of AID/APOBEC deaminases found only in Amphibians.
Statistics
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PSSM-Id: 436733
Aligned: 12 rows
Threshold Bit Score: 216.849
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5SXG_A         6 YLMDPDTFTSNFNN---DPL-VLRRRQTYLCYEV-ERLd--nGTSvkm-dqHMGFLCNEs--------gR---HAELRFL 66 
XP_012966578  33 KMLYERTFYFHFKN---LHY-ANGRKNTFLCFEV-NRMe--cGELvp---lCQGVFRKEss-------nL---HAEVCFL 92 
XP_024643276  10 KAMYPHTFYFHFEN---LQK-AYGRNETWLCFAV-EIIk--qHSTvp---wKTGVFRNQvdp----ethC---HAERCFL 72 
NP_001153887 234 DPLSEEEFYSQFYNqrvKHLcYYHRMKPYLCYQL-EQFn--gQAP------LKGCLLSEkg-------kQ---HAEILFL 294
Q694C1       195 HSMDPPTFTSNFNN---EHW-VRGRHETYLCYEV-ERLh--nDTWvll-nqRRGFLCNQaphkhgflegR---HAELCFL 263 western lowland...
NP_001233160  11 HLMDPNTFTFNFNN---DLS-VRGRHQTYLCYEV-ERLd--nGTWvpm-deRRGFLCNKaknvpcgdygC---HVELRFL 79 
XP_011887350  21 KRMKTGIFVSNFNN---KPI-LSGRNTVWLCCEV-KTKdpsgPPLda--kiFRGKVYSKa--------kY---HPEMRFL 82 
NP_001233159  10 ERMYQRTFYYHFEN---KPI-LYGRSYTWLCYEV-KIRk--dPSKlp---wDTGVFRGQvys----kpeH---HAEMCFL 72 
XP_018874149  10 ERMYRGTFSYNFNN---RPI-LSRRNTVWLCYEV-KTKg--pSRPp----lDAKIFRGQvyf----qpqY---HAEMCFL 71 
XP_011819594  10 ERMYRRTFYVNFEN---EPI-LYGRRYTWLCYEVkISKdpskLPWdtgifrGQVYFEPQ----------Y---HAEMCFL 72 
XP_013008555  31 DCLYQSTFYFHFEN---LPN-ADGRHKTFLCFEV-KNR----NEVl-----HKGFFLNQpsp-----frL---HAELSFL 88 
2NBQ_A         6 YLMDPDTFTFNFNN---DPL-VLRRRQTYLCYEV-ERLd--nGTWvlm-dqHMGFLCNEaknl---lcgFygrHAELRFL 74  human
5SXG_A        67 DLV---PslqLDPAQIYRVTWFISWSPCFSwgCAGEVRAFLQENTHVRLRIKAARIY-DY-DPL--YKEALQMLRDAG-- 137
XP_012966578  93 YWFhtqVlgmLPPGEKYKITWYMSWSPCSE--CAAEVTRFLDTHRNLSLAIFSSRLYyFW-KSD--YQDKLRRLNQAG-- 165
XP_024643276  73 SWF---CdntLSPKKNYQVTWYISWSPCPE--CAGEVAEFLATHSNVKLTIYTARLYyFW-DTD--YQEGLRSLSEEG-- 142
NP_001153887 295 DKIr-----sMELSQ-VTITCYLTWSPCPN--CAWQLAAFKRDRPDLILHIYTSRLYfHWkRP---FQKGLCSLWQSG-- 361
Q694C1       264 DVIpf---wkLDLHQDYRVTCFTSWSPCFS--CAQEMAKFISNKKHVSLCIFAARIY----DDQgrCQEGLRTLAEAG-- 332 western lowland...
NP_001233160  80 CEV---PswqLDPAQTYRVTWFISWSPCFRrgCAGQVRVFLQENKHVRLRIFAARIY-DY-DPL--YQEALRTLRDAG-- 150
XP_011887350  83 RWFl--KwrqLHRDQEYEVTWYVSWSPCTG--CANSVATFLAKDPKVTLTIFVARLYyFW-KPD--YQEALRVLCQKRgs 155
NP_001233159  73 SRF---CgnqLPAYKRFQITWFVSWNPCPD--CVAKVIEFLAEHPNVTLTISTARLYyYW-GRD--WQRALCRLRQAG-- 142
XP_018874149  72 SWF---CgnqLPAYKCFQITCFVSWTPCPD--CVAKLAEFLAEHPNVTLTISAARLYyYW-ERD--YRRALRRLRQAG-- 141
XP_011819594  73 SWY---CgnqLPAYKCFQITWFVSWTPCPD--CVGKVAEFLAEHPNVTLTISAARLYyYW-ETD--YRRALCRLRQAG-- 142
XP_013008555  89 SWFhdtE---LSFDENYKVTWYMSWSPCPE--CAKEIVTFLDNHHNVTLTIYVARLYyHW-NPT--YKEGLRALVQGG-- 158
2NBQ_A        75 DLV---PslqLDPAQIYRVTWFISWSPCFSwgCAGEVRAFLQENTHVRLRIFAARIY-DY-DPL--YKEALQMLRDAG-- 145 human
5SXG_A       138 --AQVSIMTYDEFEYCWDTFVYRqgCPFQPWDGLEEHSQALSGRLRAIL 184
XP_012966578 166 --AQIAAMDFPEFEKCWNKFVDNdgKSFRPWKRLKINFRNQDSTLWDIL 212
XP_024643276 143 --ASMEIMGYEDFKYCWENFVCDdgEPFKPWKGINTNFRFLERRLWKIL 189
NP_001153887 362 --ILVDVMDLPQFTDCWTNFVNPk-RPFWPWKGLEIISRRTQRRLRRIK 407
Q694C1       333 --AKISIMTYSEFKHCWDTFVYHqgCPFQPWDGLEEHSQALSGRLQAIL 379 western lowland gorilla
NP_001233160 151 --AQVSIMTYEEFKHCWDTFVDRqgRPFQPWDGLDEHSQALSGRLRAIL 197
XP_011887350 156 phATMKIMNYNEFQHCWNKFVRGrrEPFEPWENLPKHYTLLHATLGELL 204
NP_001233159 143 --ARVKIMDYEEFAYCWENFVYNedQSFMPWYKFNDNYAFLHRMLKEIL 189
XP_018874149 142 --ARVKIMDDEEFAYCWENFVYSegQPFMPWHKFDDNYAFLHRTLKEIL 188
XP_011819594 143 --ARVKIMDDEEFAYCWENFVYNegqPFMPWDKFDDNYAFLHSKLKEIL 189
XP_013008555 159 --TRLYTMAFPEFEDCWSLFVCN--ETFRPWENFHKCCSLQDKTLQKIL 203
2NBQ_A       146 --AQVSIMTYDEFEYCWDTFVYRqgCPFQPWDGLEEHSQALSGRLRAIL 192 human
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