Conserved Protein Domain Family
Glyco_transf_10

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pfam00852: Glyco_transf_10 
Glycosyltransferase family 10 (fucosyltransferase) C-term
This is the C-terminal domain of a family of fucosyltransferases. This enzyme transfers fucose from GDP-Fucose to GlcNAc in an alpha1,3 linkage. This family is known as glycosyltransferase family 10. The C-terminal domain is the likely binding-region for ADP (manuscript in publication).
Statistics
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PSSM-Id: 459962
Aligned: 81 rows
Threshold Bit Score: 183.14
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFX69882     199 NKKKKKLVGWYVARCGSMSKREGYINELKEYIQVDSF---GPCGNLScpetngspgEALQPCLDMLADNYKFVLAFERFI 275
EFX86566     192 AKGKTKLAIWLVSNCNARSNRQGYVKVLKNYMDVDIIskkGKCGGQDvcp----reKNSDVCYDMIETTYKFYFSFENSI 267
EFX76410     190 AANKTRLVVWMASHCATNSLRETYVKELSKYIPVDIY---GGCGNLSclhs-ktnyVSDPKCYDQLETQYKFYLSFENSI 265
EFX72914     209 FRQKTKKIAWMVSHCWTHSMRELYAKELNKYMDVDIY---GGCGNFScpth--vlhSSDPQCYDMLQSDYKFYLSFENSL 283
XP_002116220 186 AQGKTKLVAWASSKCYP--ERTTFINRLSRLMQVDKY---GKCGNLScp--------rTKGCWKRLGRQYKFYLSFENKV 252
XP_003385580 170 LKGKTIEVSALISHCVY--DRLKAVRSLMKYIDVNLM---GTCNGKW----------LSVTESHSQIKHSKFFLAFENSL 234
XP_002415567 181 WTDKTRHVLWLVSNCKTPSNREGFVQELRKFIQVDVV---GQCGHLScl------pKMSADCYHNASKVYFFYLALENSI 251
XP_974256    180 IQKRPKKIAWFVSNCGTSSERELLVNEIQKEIHVDVY---GRCGTLHce------kNNKEGCYDMMERKYKFYLSFENSI 250
EFX73033     256 IFGKKKLAAWFVSNCVTSGRREDYVKELIQYIPVDIY---GKCGNLSca--------dQTRGREMVRDHYKFYIGFENSL 324
EFX72552     190 VRRKKKLVAWFVSNCFTTSGREKYVLELQKYVEVDIY---GTCGNLTcs------hSDHIECYKMLERDYKFYLAFENSI 260
EFX69882     276 CDDFVTKRFF-DLLSRDTVPIVFGGADYT--RIAPPHSFIDALSF-NPRQLADRLLELDKSDRQYYRHFWWKDFYQVTPL 351
EFX86566     268 CEEYVTEKFF-EMMGRNIVPVVLGGADYS--AIAPPHSYISALDY-TPKQLAKYLKELDSNDTLYAEYFWWKPHYRIRNL 343
EFX76410     266 CNDYVTEKFF-EIINHNIVPIVYGGANYS--QFAPHHSYINALDF-TPEKLAQYLLLLDANDNFYNEYFWWKDHYRVESG 341
EFX72914     284 CKDYVTEKFF-KVMDHDIVPIVYGAADYA--RHAPPHSYIHAGKF-KPKELADYLKLLDANQTLYEEYFWWKDHFRVESS 359
XP_002116220 253 CKDYVTEKFYaNALLYDMVPIVLGGANYQdpQVAPPGSYINAFDFkNIEELSQYILKVDKDDSLYNQYFQWRANYTIVRM 332
XP_003385580 235 CVDYITEKTYrNAYTNEAVPVILSGANLSnpLIVPPGSYIDASKFkTAKELADYLKYVGESKERYNKFFEWRNKWNI-DT 313
XP_002415567 252 CTDYITEKFY-NALTWGMVPIVMSGANYT--SVAPPRSYIDALSFqNVRHLADHLKQIAKDPLLYNSYHAWRQRYKIvw- 327
XP_974256    251 CEDYVTEKLY-NVLQRNIVPIVYGGADYN--TLAPPKSVINVMDFmSVKHLVKHLKYLDSHPEEYLKFLEWKKDYIVETa 327
EFX73033     325 CTDYVTEKLM-VGLLYDAVPIVKGGVDYT--EFAPPHSFIDVNDFtSPKQLADYLLLLDKADSLYARYFDWRRDFTVELy 401
EFX72552     261 CKDYVTEKFF-NALLFNVVPVVYGGANYH--ALAPKNSYIDVRDFsSVHHLVKYLKFLARNDSAYLHYFDWRKTppglsl 337
EFX69882     352 ls---tRPFCDlcEKLNsnLP-RKV--YRDIDA-W 379
EFX86566     344 ydt-nrKAFCDlcEALHtsPIqSSV--AKGLHQ-W 374
EFX76410     342 veqmarHAFCDlcKKLHheEGvTKF--YPELES-E 373
EFX72914     360 vddmsrHGFCDlcQKLHedSE-FKS--YAEMAS-D 390
XP_002116220 333 km---sEAFCElcYDISffRR-QKI--YHDLTTfW 361
XP_003385580 314 dswn--trwCHlcEKIHknSKlDSQqyYTDLSG-L 345
XP_002415567 328 -----rPFQCNlcQMLHeqSP-PRM--YEDINA-W 353
XP_974256    328 s----tQTLCTlcQKLNepIK-QKI--YNDITK-W 354
EFX73033     402 q----kRGWCRlcQLANddRLpPRV--YDDILK-W 429
EFX72552     338 -lprtnQGWCTlcSMLNndSLpSHS--YSNIHS-W 368
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