Conserved Protein Domain Family
PRR22

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pfam15776: PRR22 
Proline-rich protein family 22
This family of proteins is found in eukaryotes. Proteins in this family are typically between 217 and 420 amino acids in length.
Statistics
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PSSM-Id: 464863
Aligned: 8 rows
Threshold Bit Score: 435.878
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_013977742  65 GFQMAPCGCFFDPRIYRIEWATTDFGQSSLYKLTAVGGggppGAPAGGPASPGTYLLEPQHYLKAPVaapPPP--PYPHY 142
NP_001192311  65 GFQMAPCGCFFDPRIYRIEWAATDFGQSSLYKLVAVGD----GGPAGAPTSPGTYLLEPQHYLKAPVpppPPP--PYPHY 138
XP_006101155  65 GFQMAPCGCFFDPRIYRIEWATTDFGQSSLYKLAAAGG----GVPAGGPNSPSTYLLESQHYLKAPV---PPP--PYPHF 135
ELK19436      72 GFQMAPCGCFFDPRIYRIEWATSDFGQSPLYKLAAVGG----GAPAGGAPSAGTYLLEPQHYLKAPV---PPP--PYPHF 142
XP_023373834  65 GFQMAPCGCFFDPRIYRIEWATTDFGQSSLYKLVAAGS----VGPAGGPTSPGSYLLEPQHYLKAPG---PPPqtPYSHY 137
EHB15114      66 GFQMAPCGCFFDPRVFRIEWAATCFGQD-LYKLAVARG----------PTSPDSYLLEPQYYAKAPV---PP---LYPHY 128
Q8IZ63        65 GFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSG-----GPAGVPSAPGSYLLEPQPYLKAPG---LP---PYPHY 133 human
XP_013216968 242 GFQMAPCGCFFDPRIYRIEWATTDFGQSSLYKLAVAGG----------PASPGSYLLEPQRYLKGPVp--APP--PYPHY 307 thirteen-lined ...
XP_013977742 143 Q-PAPRGPQYFLPYFPPEGPGPEALGFVGDGGPPAYMELPPPLLKEGLGPPPPppvPKDNKLPSLLITLPTE------AT 215
NP_001192311 139 QpPPPGGPQYLLPYFPPEGLGPETLGFMGDGGPPAFVELPRPLIKEGLAPPPP---PKESKLPPLLITLPAE------TA 209
XP_006101155 136 Q-PVPGGPQYLLPYFPPEGPGPETLGFMGDGGAPAFVELPPPLLKEGLVPLPPp-lPKENKLPPVVIALPAE------AA 207
ELK19436     143 Q-PAPGGPQYLMPYFPPEGPRPEALGFVGDGAAPPFVELPPPLLKEGLVPPPPplpPKENKLPPLLITLPAE------AA 215
XP_023373834 138 Q-PVPGGAQYLVPYFPPEGPGPEALGFVGDGGPPAFVELAPVA-------------PKENKVAPIVITLPQE------PT 197
EHB15114     129 Q---PGGPTYLVPCFPPEGPSHESLGFMRDGGPPGFVELPPLLLKEGRAPLPP---PKDSKLSPLLLMLPAEaslpaeAP 202
Q8IZ63       134 Q-QAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPp-pPKENKPPPVLITLPAE------PT 205 human
XP_013216968 308 Q-PAPGGSQYLMPYFPPEGPGPEALGFVGDGGPPAFVDLPPPLlke---slAP---PKESKLPPLLVTLPTE------AT 374 thirteen-lined ...
XP_013977742 216 LPPGAYGHLKGRLSQFHG------PSEPLAFPSKElqg--------ggAGSALL-YPPGAAEPKVAEA-EAAPLGAGEAR 279
NP_001192311 210 LPPGTYSHLKGRLSQLHG------PGEPLTFPVKE-------------PPPSPL-YPPVSTEPKAADA-EVAPLGAGEAR 268
XP_006101155 208 LPPGGYGHLKGRLSQFLM------PGEPPAFPAKElqg--------ggTGPGLL-YPPGPGGPKAA------PLEAGETR 266
ELK19436     216 LAPGTYGPRKGRLSQFHG------PGEPLAFPAQElrg--------ggAGLGLL-YPPAHGEPKAAEV-GVAPPGAGEAR 279
XP_023373834 198 LPPSTYGHLKGNFGQFPG---------PEAFPAKE-----------------QP-FSPSPGEPKMAEAqETAPLGAGEAK 250
EHB15114     203 LPPDAYGHFQGHRGWVPGpevarsPAEPLAFPTKElqg-------sngAELGLS-HPPGPSEPKAQEA---TQLGTGKAQ 271
Q8IZ63       206 LPPDAYSHLQGHLGHFPGp-------EPLAFPVKElqg--------sgARPGVPlYPPGLSELKVAEVkEGALLGAGKAK 270 human
XP_013216968 375 LPPSTYGPLKGHLGQVHG-------SEGAARPSEPlavptkepqggsgAVPSLP-HATGP----------------GETK 430 thirteen-lined ...
XP_013977742 280 TPEAARAFVLPEKVLLEDAMKLFDCLPGNAEPEGFPRK--APGPALP---D--SRGGGDDSSSDIRSLHLPDELLSFDYS 352
NP_001192311 269 TPEVARAFALPEKVLLEDAMKLFDCLPGSAEPEGAPRKplGPGPALP---D--SGGGGDDSSGDIRSLHLPDELLSFDYS 343
XP_006101155 267 SPEAARAFVLPEKVLLEDAMKLFDCLPGGAEPEGSLRK--APGPALP---D--SGGGGDDSSSDIRSLHLPDELLSFDYS 339
ELK19436     280 RPEAAGAFVLPEKVPLEDAMKLFDCLPGGAEPQGSSRK--APVPALP---D--SRGGGDDASGDIRSLHLPDELLSFDYS 352
XP_023373834 251 APEAARAFALPDKVLLEDAMKLFDCLPGSTEPEGTPIK--APWPALPessD--GSGGGDDSASDIRSLHLPDELLSFDYS 326
EHB15114     272 VHEVARTLALPDKVLLEDAMKLFNCLPSRAKPEATECR--VPGPALP---D--SGSGRDNSPSDIRSLHLPEELLSFDYS 344
Q8IZ63       271 APKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCE--VPGPALP---D--SSGG--NSADDIRSLCLPEELLSFDYS 341 human
XP_013216968 431 APEAARAFVLPDKVLLEDAMKLFDCLPAGAEPEATPRK--LPRPGLP---DcgGGGGGGDSSSDIRSLHLPDELLSFDYS 505 thirteen-lined ...
XP_013977742 353 VPEILDTVSNVDCFF-NFKALDEEPPPRPGPPAANMVAPVVRPELP-KRKAgSSSSKKGRQGGKGKQAVGLAGAAPSGPR 430
NP_001192311 344 VPEILDTVSNVDYFF-NFKALDEEPLPRPGPPAANTTASAPRAEPPgKRKAgSSTTKKGRQGSKGKQATGPTTAASSGPR 422
XP_006101155 340 VPEILDTVSNVDYFF-NFKALDEEPPPCPGPPAITIAAPVLRAEPPsKRKSgASATKKGRQGGKSKQAMGLASAPPPGPR 418
ELK19436     353 VPEILDTVSNVDYFF-NFKALDEEPPPRLGPPVATTAGPAPRAEPSsKRK--ASAIKKGRQGSKSKQALGLASATPSGPR 429
XP_023373834 327 VPEILDTVSNVDCFF-NFRALDDEPLARPGLRSVVAAAPVPHS----KRKTgSSATKKGRLAGKGKQPAAPASAASLGPR 401
EHB15114     345 VPEILDMVSNVDYLFnNFKVLDEGPPPCPRTPGADPAVPVPQASIRrKKQG-TTSTRKGKAGAKGKQA-------AAGAR 416
Q8IZ63       342 VPEILDTVSNVDYFF-NFKALDEEQPPHPGPPATNTPAPIL----SgKRK--ASTAKKGKPGRKARQPAGPASATPPGPR 414 human
XP_013216968 506 VPEILDTVSNVDCFF-NFKALDEDPPPRLGPPAADPAAPVLRSDPPgKKKA-ASAVRKGKLGGKGRQV-----AAPVGPR 578 thirteen-lined ...
XP_013977742 431 QDLGAPPH 438
NP_001192311 423 QDLGATPH 430
XP_006101155 419 QDLGATPh 426
ELK19436     430 PDLGTTPH 437
XP_023373834 402 QDLGAVSH 409
EHB15114     417 QDLGAAPH 424
Q8IZ63       415 EDLGATPH 422 human
XP_013216968 579 QDLGVTPH 586 thirteen-lined ground squirrel
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