1E91,2LD7,2F05


Conserved Protein Domain Family
PAH
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pfam02671: PAH 
Paired amphipathic helix repeat
This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions.
Links
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Statistics
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PSSM-Id: 460645
Aligned: 349 rows
Threshold Bit Score: 26.2303
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1E91_A         26 EIYRSFLEILHTYQKEQlhTKgrpfrgmseeeVFTEVANLFRGQEDLLSEFGQFL 80   house mouse
EMC95117      679 gTFSEFLKLCNLFNQDLidRAt----------VAFRAKSFIGNHPDLTKWFENFL 723 
XP_009155370  727 ASYAEFLKLINLYTQDLidKYt----------LADRVGSFIGNSPELMNWFKNFL 771 
CCT64667      674 STMNEFLKLCNLFSQNIidRNt----------LFHKGALFIGANPDLLNFWKTFv 718 
EGY17289      655 tsYNEFLKVCNLFSQQIidRPt----------VYQKGSVFLAANPELLSFWKQFL 699 
EFQ25512      650 taFNEFLKVCNLFSQSIidRNt----------VFHKGSVFFAANPELMGFWKAFL 694 
XP_007856602  451 EIYEEFLKLLSLYSKEIidVKt----------LLDRTGAFF--DGDLLEEFKELv 493 
EAU92595      540 EVYEEFLKLLSLFSKDIidAKt----------LIERAKVFL-GDENLMAEFKDli 583 
XP_003037381  371 EMYEDFLKTLTLFSKDIfgVKd----------LIDRAKVFL-GDGDLLAEFKELL 414 
XP_001874054  495 EVYEEFLKLLGLFSKDIfdVNt----------LIERTRVFL-GDGELMSEFKDLv 538
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