6WNL


Conserved Protein Domain Family
DRMBL
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pfam07522: DRMBL 
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DNA repair metallo-beta-lactamase
The metallo-beta-lactamase fold contains five sequence motifs. The first four motifs are found in pfam00753 and are common to all metallo-beta-lactamases. The fifth motif appears to be specific to function. This entry represents the fifth motif from metallo-beta-lactamases involved in DNA repair.
Links
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Statistics
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PSSM-Id: 429512
Aligned: 29 rows
Threshold Bit Score: 98.5023
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6WNL_B        238 PEILHHLTTD-RNTQIHAC-RHP------KAEeyfqWSKLPCGITSRNRI-PLHIISIKPSTmwFGERSRKTNVIVrTGE 308  human
Q5QJC2        239 PEILYHITTD-RYTQIHAC-RHP------KDDdyvrGNRLPCGITCQNGT-PLHVISIKPSTmwFGERIKKTNVIVrTGE 309  chicken
Q5RGE5        239 PEILCHVTTN-RATQIHAC-RHP------KDEeffrANRLPCGSTAPDGI-PLNIISIKPSTiwFGERTRKTSVVVkMGS 309  zebrafish
NP_564070     230 mvivpEIVSEdPSSRFHIFsGFP------KLY----ERTSAKLAEARSKL-QSEPLIIRPSAqwYVCDDEDDWKSGsIQK 298 
Q8RZQ7        227 SLIAPEIITEdPSCRFQIL-GFQ------NLY----DKACTKIEEARASL-QPEPLFIRPSTqwYAHCAQSqkpslte-- 292  Japanese rice
Q8IK95        674 KHILNKITDNkLEAQIHIV-DINysyifpKID----KRKFLNLIDEEIEKeFDSFYYIIPTG--WVKKFSfyer------ 740  Plasmodium fa...
Q4Q2L8        388 EHLLSVFLVPmASVGYRAVaALA------HADgp-aVMDMEDGLALNLDR-YDQVLMVEPTG--WSKRCVAREVSEky-- 455  Leishmania major
EAY09804      231 FAKPELFSEDpYLTRIHLL-PIQ------ECG----KEKVSLYAASMG---FDSVTAIRPSG--WNGRPFWRCPTFdIYN 294 
EAX84063      225 YCSESCFTNDpTKTRVYLV-PIM------DCN----SVSASVWAKQNG---YSSVCAIAATG--WSGKAGWKNPQItYQG 288 
XP_001597515  835 PELTSRLTSDpREAQIHMQ-MLM------ELR----PETLQDYLTGYKPH-FTRVVGFRPSG--WSYKPPNSRFVD--SP 898 

6WNL_B        309 S------------------------------SYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPVG 344  human
Q5QJC2        310 S------------------------------TYRACFSFHSSYSEIMDFLSYIRPVNVYPNVLPVG 345  chicken
Q5RGE5        310 S------------------------------SYRACFSFHSSYLEVKDFLSYICPVNIYPNVIPLG 345  zebrafish
NP_564070     299 Qrkvrfse----------------avkdefgLWHVCYSMHSSRAELESAMQLLSPKWVVSTVPSCr 348 
Q8RZQ7        293 ------------------------avldgcgVWHICFSIHSSRDELEQALELLQPQWVISTTPPCF 334  Japanese rice
Q8IK95        741 ---------------------------nnisIFLIPYSEHSNLDELKNFVKSIKPCNILPTVFYNE 779  Plasmodium falciparum 3D7
Q4Q2L8        456 ------------------------------tLLRVPYSEHCAFHELLEFVAFVNPARVVPTVSEEG 491  Leishmania major
EAY09804      295 Eik--------------------------vtSYDVPYSDHSSPMELTEFVKAVKPAKVIPTTTKNK 334 
EAX84063      289 Pik--------------------------vtLYEVPYSDHSSPQELLNFVKVVKPKKLVSTTSRSQ 328 
XP_001597515  899 PihtilnasnwrseydmgelipqrgstkeaqCFGVPYSEHSSFRELTMFVMGLRIEKVVPTVNVGT 964
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