Conserved Protein Domain Family
PAS_4
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pfam08448: PAS_4 
PAS fold
The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. This domain is associated to signalling systems and works as a signal sensor domain. It recognizes differently substituted aromatic hydrocarbons, oxygen, different dodecanoic acids, autoinducers, 3,5-dimethyl-pyrazin-2-ol and N-alanyl-aminoacetone (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Links
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Statistics
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PSSM-Id: 312075
Aligned: 49 rows
Threshold Bit Score: 53.572
Created: 23-Mar-2022
Updated: 13-Oct-2022
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q826L6       136 ATESSVGLTIF-DSDMRVVWGNI-STD-LELGGVAQYTGRPAA--DLFPEGefisrhHPPDEDQIMEHVLTTGEPIIGMH 210 Streptomyces av...
Q9I4E2        27 FDGLRQPVTVV-DPSGRFVYYNRaSGL-LDGLDPQRALGMHLL--QSAPW-------LAAEQSTLLRCLAEGRPSIDTLQ 95  Pseudomonas aer...
Q98GU5       254 LASIGQAVIST-GRDGRLDYMNAvAEK-LLACPFGATRGKPIA--SLFRLVdk---dTGVEETQLVGRLLAGEARRSSAR 326 Mesorhizobium loti
Q1D0A1       207 LSSMPSGLATC-DAQRRVTYVNPaGCG-ILQVDPTQVAGVEVE--ALLPGV------SVLAPRSPRSELVVGK------- 269 Myxococcus xant...
Q9HQB9       140 LDSAMDGIAMIdDAEQTVQYANAsFTG---GTDAERVRGQSWQ--SLYPSE------SHGPIADALVALDDGDQQQWQGI 208 Halobacterium s...
Q9A599        22 VEASQDCIRVI-SADGYLEYMNAqGKF-LLEIEDFEGRNRHQYwpDMWPLE------SRDTVEQALRAAMAGNAVAFRAP 93  Caulobacter vib...
Q9HRG1        26 YRPQSWYAGVV-GPDGRIEYANEaARD-VIGADARDLVGTFFWqaPWFTHDq----dVQAAVREQVAAAVQGEASQFTAT 99  Halobacterium s...
WP_003484266 143 FEHISAPIAVV-DANLHMHEANAa---------FQRLIGSATPgaAIHAAGl-----DQAAAVHALTTALAQRERWSGTL 207 Xanthomonas
Q88KD6       289 WELSQDLLAVL-NKDLTPVALNPaWEA-SLGFSRERLSQSSLL--HLLPEH------DQEQLLTELAALAHGRTSARFVG 358 Pseudomonas put...
Q89I31       347 FDHTPMAIATV-DRGGNVVRANArYAKlAQGLGLDSASKSIFR---AINSR------DRHLVITAINQAAEGKADIAPVE 416 Bradyrhizobium ...

Q826L6       211 YRGRapadPGREHVWSCSY--HRMLDARGE-PLGLFEESLDITDRYR 254 Streptomyces avermitilis
Q9I4E2        96 AYVGa---GGELLQYRHRA--IPLRGRDGC-LLGAMELGEVVAETEE 136 Pseudomonas aeruginosa
Q98GU5       327 PQLLqr-pDGSVVPVALTG--APLL-VSGD-VVGAVLAFHDMTREED 368 Mesorhizobium loti
Q1D0A1       270 --------GAKRRILGLSV--TPLEGEPGA----LLMVFQDLTQLRR 302 Myxococcus xanthus DK 1622
Q9HQB9       209 VTACg--aDGTTYPQELTM--TAVAD-------GYVWVCRDVTDRRD 244 Halobacterium salinarum
Q9A599        94 CPTA----KGAPRWWDTTV--SPI--LEGGrVIRVLATSRDVTGERL 132 Caulobacter vibrioides
Q9HRG1       100 HRTS----GGGTATVELELqpMPAPAVDGIdDHDHAFAVVVVGRRAA 142 Halobacterium salinarum
WP_003484266 208 SLLR----DGKLCETEWRV--SPYREPDLG-----LLLVEDVTEQRL 243 Xanthomonas
Q88KD6       359 RILHa---GGQQRWLSWVV--VPEDT-------LLYVVARDITSERE 393 Pseudomonas putida KT2440
Q89I31       417 VALE----GTKERWGQFFV--TPVDAAEND-AEAAIVHMLETTERRA 456 Bradyrhizobium japonicum
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