Conserved Protein Domain Family
Sec_Non_Glob

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TIGR04420: Sec_Non_Glob 
Sec region non-globular protein
Members of this family occur only in the genus Leptospira, always encoded between genes for the YajC and SecD components of the Sec preprotein translocase. Sequences have an N-terminal signal peptide and a C-terminal transmembrane segment. Between these are regions of non-globular, low-complexity sequence including Lys-rich and Ser/Thr/Asn/Glu-rich regions.
Statistics
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PSSM-Id: 275213
Aligned: 7 rows
Threshold Bit Score: 225.555
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_004750585   1 MKKISVLILIFLFlgNLALFSQDGEEIDFLEKVTEPKKTVSKKSSNTAG---T---SSGTSTPKKKEKKRSKkkrSKKSS 74  Leptospira kirs...
WP_010569280   1 MNKILCLLLSFLI--SFPVFSQDGEEIDFLDKVGEPKKATTSASKKAQA---A---KVPKKKKSKKGSKKRK---SSEVR 69  Leptospira broomii
WP_016543313   1 MKKILCLLISFAL--TFSLFSQDGEEIDFLDKVSEPKKSSTASKQGTNA----------KTVKKKKGKKGAKkkkGIEAK 68  Leptospira wolffii
WP_015675805   1 MKSFFSILIFLGL--TTSLFSQEG--LDFLDKVNDKPKTTT-KPKEDTVqttT---KKQSGVVTTTGVTSGKkkkSKKKS 72  Leptospira yana...
WP_015682674   1 MKRLFFISLIFCF--SASLFAQEG--LDFLDKVNDKPKSTTTKPKEETV---TpttKKQTNVVTTAVTTTGKkkrSKKKS 73  Leptospira wolb...
WP_004499395   1 MKKAAVSILIFLFlgNLSLFSQDGEEIDFLEKVSEPKKKTVSKKSSNSG---S---SNGSKISKKKEKRKFKkkkSKKFS 74  Leptospira weilii
WP_020770643   1 MNKILCFLLSISL--AFPIFGQDGEEIDFLDKVSEPKKTTTSSKKTPLA-----------KASRKKKVKKNAgkkKKAVE 67  Leptospira sp. ...
WP_004750585  75 SSLPNNLEETQKKNINHNE---------TSs--GNDHSNLNGgnSGSSNTLESGNVDEqrtS--ASKIdLKDLPKPYWVN 141 Leptospira kirs...
WP_010569280  70 QDGVEQKEGETKKKVEATG---------IP---DDAKNDSHPgdDGHSKNSENASSEK---A--LKKEePGDLQKPYWVN 132 Leptospira broomii
WP_016543313  69 KEELAPKDGEPKKKIETDI---------PPedpDQGKNSGDP--SGSEKALEKTSARDl--S--ANTDsTGEPQKPYWLN 133 Leptospira wolffii
WP_015675805  73 KQNQLATEN-LPQNNNLVA---------NP--------------NGNPVVTEKTLVPGekqP--AVLEeEEVVSNAYWMD 126 Leptospira yana...
WP_015682674  74 KQNQLVTTETLPQNTNLAA---------NP--------------NTNTTVTDKSFPGLekqP--TVLEeEEVVHNGLWMD 128 Leptospira wolb...
WP_004499395  75 T-VPTNPENS-KKNTEPDNnegnssgnnTSn--DSQNNGSNSsnNISNSNAQSGNIDAqplAnaSKTD-LKELPKPYWVN 149 Leptospira weilii
WP_020770643  68 SKETEQKESEPKKKVDPEI---------APedpTQGKNSGDP--NGPNETTERNLNKEv-----SNPEvSAEIQKPYWLN 131 Leptospira sp. ...
WP_004750585 142 EEVKIHPNNLPGYTVs--Q-KSEQGSSFGSELSEILKLGEDKKKEENKK---KVQEVQKSGSFTGFLSEYKKPIIIIVFI 215 Leptospira kirs...
WP_010569280 133 EETALTPRHLPGYAEt-sAaLPKEDISFKDKLGDILKMGQDKKKEEEKR---KAAEQKDQSTIVSFFSEYKKPIIILGLI 208 Leptospira broomii
WP_016543313 134 EETRLTPNHLPGYDAsatA-APQEDHSIREKLGEILKIGQDKKKEEEKR---KAAEQKDQGVILGFFSEYKKGIIILTIV 209 Leptospira wolffii
WP_015675805 127 SQVSVEPTGLPGFSSd-------------------LKLAKSEVSNSTSEssvNKDSGKSFFNVSDFFAKYKKAMMILGII 187 Leptospira yana...
WP_015682674 129 SNVSVEPSGLPGFSAd-------------------LKIGKTEGSKSEVSfspNKETGKSLFNFSDFFAKYKKAMMILGII 189 Leptospira wolb...
WP_004499395 150 EEMKVRPNNLPGYSVe-sE-TSEQGASFRNSLSEILKLGEDKKKEEEKK---KVQGGQKSGSFAGFLSEYKKPIIIVVFI 224 Leptospira weilii
WP_020770643 132 EETTLSPRNLPGYNAnvsS-LPKEDISIREKLGEILKLGDDKKKEEEKK---KAAEQKEQGAIAGFFSEHKKAIIIIAII 207 Leptospira sp. ...
WP_004750585 216 LLFALYRLKAgkSRGS--SSRKSPVTINKMRRD 246 Leptospira kirschneri
WP_010569280 209 VLFALYRLRA--GGPR--ITRRSPVTINKVRRD 237 Leptospira broomii
WP_016543313 210 VAFALYQIRT--AGRR--TTKRSPVTINKVRRD 238 Leptospira wolffii
WP_015675805 188 ILFAFYRLRS--ARPG--SSSRS------YRR- 209 Leptospira yanagawae
WP_015682674 190 ILFAFYRLRS--ARPG--SSSRS------YRR- 211 Leptospira wolbachii
WP_004499395 225 LLFALYRLKA--GKSRgnSSRRSPVTINKMRRD 255 Leptospira weilii
WP_020770643 208 LAFALYQFRA--KGAR--VTRRSPVTINKVRRD 236 Leptospira sp. B5-022
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