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5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase SAICAR synthetase (the PurC gene product) catalyzes the seventh step of the de novo biosynthesis of purine nucleotides (also reported as eighth step). It converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",