5J97


Conserved Protein Domain Family
Caprin-1_dimer

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pfam18293: Caprin-1_dimer 
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Caprin-1 dimerization domain
This domain is found in human Caprin-1 protein. Caprin-1 plays a role in many important biological processes, including cellular proliferation, innate immune response and synaptic plasticity. This domain is found in the highly conserved homologous region 1(HR1) and is responsible for the tight homodimerization of Caprin-1.
Statistics
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PSSM-Id: 436391
Aligned: 19 rows
Threshold Bit Score: 142.352
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5J97_A         8 RREHXLKLEAEKKKLRTILQVQYVLQNLTQEHVQKDFKGGL-------NGAVYLPSKELDYLIKFSKLTCPERN---E-S 76  human
XP_011444906  98 KKEKADRQGMEVKRIGDILRYQNLLDAMGSEKVRSDFQTGK-------HGAVVLTEENLKQLDDLYKLLSPSRE---G-E 166
KZS14273     103 KKEIFEKQQHELARFKELFIIQEVFSCLCSPAAREDFLNGM-------HGSPQLTDSDLQKLDTFYSLVSIDRQ---NlP 172
XP_015786463 101 RKERPTRDPKEIERLRLVFQFQDLLGSLN-ADVKNDFLNGT-------NGATQITEEKLQHLEEFSKLIDSEKN---K-V 168
KRY19644     157 KKEHRDRMQAEHARFRNLLNMQELLNVLGNNDVRVHFAEGT-------EGAVKLSPEDLHLLDFLYQKICPSYDdvhQ-D 228
EEN64583      98 KRQLLAQREVELKRVQDLLEIQHVLDLLGTDAVRDDFKQGK-------PGAVPLTEAQLTQLDELYKVINPETE---E-G 166
XP_022525820 109 RREQLKREEVERRRLKAVLEVQYVLDQLGEESVRQELRQPAgsgsgngEEGPLLSEAELSSLDEFYKLVGPDRD---P-N 184
XP_010176638  60 RREQLMREEAEQKRLKTVLELQFILEKLGDDEVRNDLKQGS-------NGVPVLTEEELTMLDDFYKLVYPERD---M-N 128
XP_009031645  88 KRDKIERQNQEISRFKEILKLQKVLSHVDSELMKPDFKSGRlyk-hlvNISTNNDEQQLKMVREFKQLIESSKT---A-G 162
XP_014914007 140 KKEQIAKMETERRHLALVLQFQHLLGGLQQEHIRKDVMAGC-------NHAPYIPAHQLHSLDQLAAMVGVKRD---G-R 208
5J97_A        77 L-SVEDQXEQSSLYFWDLLEGSEKAVV-GT-TYKHLKDLLSKLLNSGYFE 123 human
XP_011444906 167 S-NYAEELTKASEHFASLLDGKDKPVV-GT-TYKDLKVLIDLIDDCGYFE 213
KZS14273     173 K-TFNDAVLSSAVHFQHLMEGRNKEVA-GS-TYREIKDLIFSIINNGYFD 219
XP_015786463 169 DeTSNKPHIKTAERYLALVEGVRSDAFkGT-SYKELKETLTSINECGYFN 217
KRY19644     229 E-TWASVLNESADCVCMLLSASQKLVP-TFnVIRTVRAVIDGILECEFYK 276
EEN64583     167 T-SLSSQQADASEHVLCLLDAREKEIA-GT-TYKDLRELLQEVVNCPYWD 213
XP_022525820 185 V-RLTDQFEEASLHLWELLEGRDKAVA-GT-TYKALKEILDKILQSGYFD 231
XP_010176638 129 M-RLNEQYEQASVHLWDLLEGKEKPVC-GT-TYKALKEIVERILQTSYFD 175
XP_009031645 163 T-SYACQMQAAAEHLFLYLEKSEKPVV-ESlTYKDVSQLVDGIFESAYFD 210
XP_014914007 209 M-SLAEQMDQAALVYIDLLDGKDKPVA-GS-TYKLLKDELIRLLKYNFFS 255
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