Conserved Protein Domain Family
NFACT-C

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pfam11923: NFACT-C 
NFACT protein C-terminal domain
This is the C-terminal domain of the NFACT (NEMF, FbpA, Caliban, and Tae2) proteins involved in the ribosomal quality control pathway. This context is conserved in archaea and eukaryotes, but NFACT proteins in bacteria lack the NFACT-C domain.
Statistics
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PSSM-Id: 432191
Aligned: 124 rows
Threshold Bit Score: 91.8128
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KLJ05556      999 SAADLSCLPSLIGTAVAGDEIVAAIPVCAPWMALGQYKYRAKLQPGTLKKGKAVKEIYGKWVVdattavnamekgkgrrk 1078
EFN57403     1048 ERDKLTQLDQLTGVPRGEDILLFAVPVCAPYQVLASFKFKVKIIPGTLKKGKAARQAAELLLK----------------- 1110
XP_011400493  733 DRLRLTDLDALTGLPRPDDVLLYALPVCAPYQVLTSYKFKVKMVPGPQKKGKAVRQAMELFQR----------------- 795 
BAM80593     1236 ELANLSELDLFTGCPHPDDVLEYALPVCAPYQTLAKYKYKVKLVPGTLKKGKALKQVLGVVQSqersgar---------- 1305
EXX69639      969 TMESLTVLDTLTGSPLPEDNLLFAVPVCAPYISLQKYKYKVKLTPGSTKKGKACKTAISFFLN----------------- 1031
EPZ35291      834 NEETLTFIDSLTGCPQADDIILFAIPVCAPYSCLSNYKFKVKLTPGSLKKGKASKMALNLFLQ----------------- 896 
KND01393      390 EESNLTFLDSLTGQPHPADILLHAIPVCAPWSALQRYKYKVKLLPGSLKKGKATKSAVSAFVAiatdeesravs------ 463 
XP_006675014  579 QAIDMSFLDLLTGQPHETDNLLYAIPVCAPWTALQKYKYKVKLLPGALKRGKAAKSITASFLSm---------------- 642 
EGD80490      828 LTQSLSNLHSLTAQPTPEDTVLYALPVCAPYSATQGYALRAKLVPGNTKKGRAIRGVVQTFVS----------------- 890 
EDQ92617      957 EEDQLTYLDALTGLPHPDDELMFALPVVAPYGAVRQYRFKAKIVPGEQKKGKAIRSLIHHFCT----------------- 1019
KLJ05556     1079 ekdegeaevgeedvnervDGEEGKGEDgtthgLKQLARMELELIKGWREVEIMNTLPVSKVKIV 1142
EFN57403     1111 --------------------------------GGEASQRERDLLRAVPEQEAISCLCGKGVRIQ 1142
XP_011400493  796 ------------------------AAD--------TTSRERDLCRAVPEPEAVITLV-GTVKIQ 826 
BAM80593     1306 -----------ttnaanaGADASEVAQ-----GAAATARELELIQAVDETVLVQQML-GNVRVL 1352
EXX69639     1032 --------------------------------DPQLTPREKELVKSIPDTEMTLVML-GKCKVS 1062
EPZ35291      897 --------------------------------IKELSQREKEVIKAVPENELINQML-GKVKVS 927 
KND01393      464 -------krgrgrggetnSVEDNDGEEqn--sIVDAAKRQKDLIKAIPEMELINSML-GKVKVM 517 
XP_006675014  643 ------------------AAANESVAE-------------KELIKAVPDADWISTVL-GKVKVV 674 
EGD80490      891 --------------------------------GGQCTEEQASLITAIKDADLYNGVP-TRVKVM 921 
EDQ92617     1020 --------------------------------ETGASSAEVDVIKAIKDLELFRSVP-GKIKVM 1050
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