Conserved Protein Domain Family
SNAPC1
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pfam09808: SNAPC1 
Small nuclear RNA activating complex (SNAPc), subunit 1
Members of this family are part of the SNAPc complex (SNAPC1) required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. They bind to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Furthermore, they also recruit TBP and BRF2 to the U6 snRNA TATA box.
Links
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Statistics
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PSSM-Id: 430842
Aligned: 64 rows
Threshold Bit Score: 113.497
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_001994197       5 VYGDCWKLLQRFSSavaataGQDAKFELFCEMWH---TLRMQHIYSAQTNHIEVIETTMAALHVAKRVAC--GRrtngda 79 
EFA85807         275 LLEAIRNVIFKFQQ------STEFTFSTFKEIWKq--EACLLEFFEIQPHQPELIHI---LYYGVIGYTLmn-------- 335
EGC37046          98 LLKIIKEIIYQYQQ------KNVVSFSEFKELWKy-kMDTLGPFFESQHIYPDVIHI---LYYGVLGFTLld-------- 159
Q54B89           138 LLKLIKTIIFEYQI------KSEISFTQLKEVWKqfgSETFKIFFEAQTINHEVIHI---LYYGVLGYTLld-------- 200 Dictyosteli...
XP_004963061       6 FKLDIDELVADYGK------ENSTTLADFKRVWK---EKKFSYIYEGRPNA-NSCLFMQSLFLHCIGHLTs-ES------ 68 
XP_014757447       6 FKLDISELIADYAK------ENYTAFTDFKRVWT---AKKFSYIYEGRPKT-NSGVFMQSLFLHCIGHMTs-QS------ 68 
Q8LNT0             6 FKLDIDELLADYTE------ANCTAFADFKRLWM---AKKFSYIYEGRPKT-NSGAFMQSLFLHCIGHMTs-QS------ 68  Japanese rice
JCVI:AT3G53270.6   6 FKRDIDELIDEFVE------DDLTTFADMKSVWL---SRKFSHIYEASPNS-NLAFFMQSLYVHTIGHMVs-ID------ 68 
XP_009103854      32 FKRDIDELIDEFVE------SDLTTFGDMKRVWL---SRKFSYIYEAFPNT-NLAFFIQSLYAHTIGHMVs-ID------ 94 
A0E5H2            19 FKQDIINFIGNVLAymreknIEILSYQHFNKCWM---ENDIQFIHQCQLEWESQDDYYNLLYGIILNKLIesPL------ 89  Paramecium ...

XP_001994197      80 faaTRAERIGAIYLLYAIYNKQPTMRFIKIEVSPSTWQCLtgyvEQLRRVEAERRDTqQVSYVFWRLVQDQAFRYTALd- 158
EFA85807         336 --qPVNSKSAIVYLLYVLYTCQIIQPPIPIDITLNIWDGL----MLYFNCFKLYRLA-EPYHVFKILMDRGAFHFSAS-- 406
EGC37046         160 --lPINGKVSIIYSLYCLYNCQITNPRVPIIITLNYWETL----LQYFEDIKNQTLY-EGYQAFRFLRKMGAFVFSAT-- 230
Q54B89           201 --qPINGKACIIFLLYILYNSQICSPKQQIVLTINMWEKL----LGYFNEFKEQEIV-EAYQAFRSLRTSGAFVFSAT-- 271 Dictyosteli...
XP_004963061      69 ---SLPRRLAGLYCLYCLYECQPYKPQFKIYLSLEECRQL----KDFISMAKQNGVH-LVPALVKRMLDKGMFLFGYMn- 139
XP_014757447      69 ---SLSQKLAGLYCLYCLYECQPYKPHFKIYLSLEESKKL----KDFVVEAKQNGVG-FVPALVKRMLDKGMFLFGFVn- 139
Q8LNT0            69 ---CMPQRLAGLYCLYCLYESQPYKPHFKIYLSLEELKKL----KDFVVEAKQNGMA-VVPSLVKRMLDKGMILFGFIn- 139 Japanese rice
JCVI:AT3G53270.6  69 ---SFSRRLGGLYCLYCLHEIQPFKPKFRIYISLQELGKF----RDLVVEAKDKGVE-IAAAVAKKMLDENMLIFGAV-- 138
XP_009103854      95 ---SFSRRLGGLYCLYCLHDIQPFKPKFRIYISLQELGKF----RDLIVEAKEKGVE-IATAVGKQMLDKNVFIFGAVd- 165
A0E5H2            90 ----YFEQLSLFYLIYTIYVTLD--QKILISLDQETMNQL----YFFFQECKEKGNH-DVFLLFLELNKQNAFLLSSRvg 158 Paramecium ...

XP_001994197     159 ---yCQALDALAAYDSLESFAESKk-TKNKTAllkhQltqseanIRE------ELHSLAQLAHAAQSAC 217
EFA85807         407 ----LHPVASLPIFKTNSTTVGATviPVDLVG-------------VNllngliNLDHLKDIHEQYNQAK 458
EGC37046         231 ----LHPISTMNYFKTNSMQTNQPiiPHEIIN-------------NDpikplrNIKELKQITEQYNLAK 282
Q54B89           272 ----LHPVSTMNIFKTNSIALKSSviPPDLVG-------------QDttkslkELSELERIHNAYNSAK 323 Dictyostelium discoide...
XP_004963061     140 ---lLGDNGEKQVEELTAMQNKRIkfACDKLF----AntqaesyMHLdlgaefELDSIKKLSKEYAEAK 201
XP_014757447     140 ---lLGVHGAKQVDELNESQNKRVkyACDKLF----AntqiesyMRTdlgeefEVDNIKKLSMDYAKAK 201
Q8LNT0           140 ---lLGDSGVKQVNELTASQNKRVkfACDKLF----MntqidsyMHMdlgselELDKIKKSSLDYAKAK 201 Japanese rice
JCVI:AT3G53270.6 139 ----DETSATKTIHQLTELQNARVrfAYEKLI----CdtsinqfIHLdmgkevDLNSLDKMSIEYAEAK 199
XP_009103854     166 ---fDETSTTEKLHQSIELQNRLVrcAYKKLT----SeteidkfIHLdmgkevDLSSIHKQSIEYAEAK 227
A0E5H2           159 ckrlSIHPCGLPYIITKRNKAQLKqiTEERED------------EQEkvertdLTKQLLNASEKYHKAK 215 Paramecium tetraurelia
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