2Q7D


Conserved Protein Domain Family
Ins134_P3_kin_N
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pfam17927: Ins134_P3_kin_N 
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Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain
This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase. This entry represents the N-terminal pre-ATP-grasp domain.
Links
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Statistics
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PSSM-Id: 407776
Aligned: 5 rows
Threshold Bit Score: 143.385
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2Q7D_A  20 RVGYWLSEKKIKKLNFQAFAELCRKRGMEVVQLNLSRPIEEQGPLDVIIHKLTDvileadqndsqsLELVHRFQEYIDAH 99  human
Q7XBW0  17 LIGYALAPKKQQSFIQPSLVSRAAGRGMDLVPVDPSRPLPEQGPFHLLIHKLYG------------EEWRGQLDAFSAAH 84  Japanese rice
Q9SBA5  10 LVGYALAAKKQHSFIQPSLIEHSRQRGIDLVKLDPTKSLLEQGKLDCIIHKLYD------------VYWKENLHEFREKC 77  thale cress
Q33BI9  45 VVGYALTKKKVKSFLQPKLLSLARKKSIHFVSIDETRPLSEQGPFDIILHKLTD------------KEWQQVLEDYREEH 112 Japanese rice
Q9SUG3  42 IVGYALTSKKIKSFLQPKLEGLARNKGILFVAIDQNKPLSEQGPFDIVLHKQIG------------KEWRRILEEFRLAH 109 thale cress

2Q7D_A 100 PETIVLDPLPAI 111 human
Q7XBW0  85 PAVPVVDPPHAI 96  Japanese rice
Q9SBA5  78 PGVPVIDLPEAI 89  thale cress
Q33BI9 113 PEVTVLDPPNAI 124 Japanese rice
Q9SUG3 110 PDVTVLDPPDAI 121 thale cress
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