Conserved Protein Domain Family
thiE

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PRK12290: thiE 
thiamine phosphate synthase
Statistics
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PSSM-Id: 237041
Aligned: 11 rows
Threshold Bit Score: 654.556
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
262392847   1 MSKILIPSSLIELTGLVQQCLLLAKEQGFSiEDIELGVSPTQSIQLVRDQQTTHITTDLI-DGHNSEHES-----S-FVL 73 
54307328    1 MSSLCLPDHLTPLLMHVEPLLANADQYQLG-NTVSVSVSESGVVDIKIEERQLSLIFNQAeADFSGFKIL-----DqWYA 74 
229606621   1 MVRLVFPRHLSALIGHVQYALLQAKEQGVAiQHIRLDVGSEAQFILEKSEESLRIGSSLC-SQKEGFEPC-----D-YYL 73 
147674784   1 MVRLVFPRHLSALIGHVQYALLQAKEQGVAiQHIRLDVGSEAQFILEKSEESLRIGSSLC-SQKEGFEPC-----D-YYL 73 
227080298   1 MVRLVFPRHLSALIGHVQYALLQAKEQGVAiQHIRLDVGSEAQFILEKSEESLRIGSSLC-SQKEGFEPC-----D-YYL 73 
156972706   1 MSKILIPSSLIELTGLVQQCLLLAKEQGFSiEDVELGVSPTQSIQLVRNQQTTRITTDLI-DGYDSEHES-----S-LVL 73 
28899800    1 MAKILIPSSLIPLTGAVLQCLLLAKEQGFSiDEIELGVSPTQFIQLVLGQNTFRVGTDLI-DVCEEAETA-----D-FVL 73 
37681390    1 -MRLLIPSAIIELTGEIQQCLLLAKQQGFAiDHIELGVSPTRTLQLISSAKTVVFETDLIhNDSRHLGAH-----D-FAL 73 
27364402    1 -MRLLIPSAIIELTGEIQQCLLLAKQQGFAiDHIELGVSPTRTLQLISSAKTVVFETDLIhNDSRHLGAH-----D-FAL 73 
15640094    1 MVRLVFPRHLSALIGHVQYALLQAKEQGVAiQHIRLDVGSEAQFILEKSEESLRIGSSLC-SQKEGFEPC-----D-YYL 73 
218710983   2 TVKILIPSQNIELTGEVQNCLLVAKRQGLAtDAVELGVSPTKYFSIVDTQQALSIGFA---YDVDSLAECqlaelN-HVV 77 
262392847  74 YYRSSLSVEACA--KQPSK---AIYIGIADtqvs----denEKVlQLDIWRHPLNDEVRALSVKSKPnam-----fdpEH 139
54307328   75 PYPSVREMQVKV--EQDSR---VIVCGLPT-----------EKG-CVDIWHHNGEARAVYCHHAGAG-----------EP 126
229606621  74 DYVSENRVLPEAmmCNARC---TVTVGLHD-----------EYGfTLDKWQYGHAAEQLIVYPSENHrln-----skvNQ 134
147674784  74 DYVSENRVLPEAmmCNARC---TVTVGLHD-----------EYGfTLDKWQYGHAAEQLIVYPSENHrln-----skvNQ 134
227080298  74 DYVSENRVLPEAmmCNARC---TVTVGLHD-----------EYGfTLDKWQYGHAAEQLIVYPSENHrln-----skvNQ 134
156972706  74 YYRSALSVEACA--KQPSK---AIYIGIADtqvs----dekEKElQLDIWRHPINNEVRALSVKSKFnam-----fdpEH 139
28899800   74 YYQSGLSVSECR--QQPSS---AIFIGIQDvesklddsvktTSAdVLDIWRHPVNDEIRALSVASTSrttt----lqtDQ 144
37681390   74 HYHHSLALTEVSsyLGSECkakTLLINLQG-----------EQGeAFDVWQHPLADETRALRFLSRQnhsqnesvesiYR 142
27364402   74 HYHHSLALTEVSsyLGSECkakTLLINLQG-----------EQGeAFDVWQHPLADETRALRFLSRQnhsqnesvesiYR 142
15640094   74 DYVSENRVLPEAmmCNARC---TVTVGLHD-----------EYGfTLDKWQYGHAAEQLIVYPSENHrln-----skvNQ 134
218710983  78 DYSNSVALTDVCdaFTQTPn--TIYIGVS------------DDSvVLDIWSHLYANRAIKSDTTAHQel-------dnHG 136
262392847 140 HLAWIVTLTALDFPIEDALTLARGILTQQANVSRETllndkldegrstkWADQFDDFPTPVL-EDNRLGIQVGWSAQGES 218
54307328  127 QRAMLLCALALDYPLEDAVTLARAHARGYQSSHQDGhge--------vsWPVSRELFPRPLTaNHPEVDVLGWQSKEVAV 198
229606621 135 HLAWVLATLTLDFSIGDGLCIARAAITQGDSVSRET-------------WPTQFERFPAVQS-NIRSLSTQVFLT----T 196
147674784 135 HLAWVLATLTLDFSIGDGLCIARAAITQGDSVSRET-------------WPTQFERFPAVQS-NIRSLSTQVFLT----T 196
227080298 135 HLAWVLATLTLDFSIGDGLCIARAAITQGDSVSRET-------------WPTQFERFPAVQS-NIRSLSTQVFLT----T 196
156972706 140 HLAWTVTLTVLDFPIEDTLTLARGMLTQQANVSRETllndsldegrstqWADQFDDFPTPVL-EDNRLDIQVGWSAQGES 218
28899800  145 HLAWTVTLLALDFPIEDALTLARPMT----NVSRETlinget--mvkqeWASQFADFPTPVL-EDCRLGIKVGWSSHGQS 217
37681390  143 HLAWVVTLSALDFPIEDCLTLARAML----NVSRET-------------WVSDFALFPTPVL-HLDEFGILPSHNLEGLT 204
27364402  143 HLAWVVTLSALDFPIEDCLTLARAML----NVSRET-------------WVSDFALFPTPVL-HLDEFGILPSHNLEGLT 204
15640094  135 HLAWVLATLTLDFSIGDGLCIARAAITQGDSVSRET-------------WPTQFERFPAVQS-NIRSLSTQVFLT----T 196
218710983 137 HFAWLLTLLALEFPLEDALVLARAS----SNVSRGT-------------WPAHYQNFPIPIL-EDERLDISVGWAHQGTS 198
262392847 219 VNFPTLTKQSLGLYPVVDDVAWIERLLPLGINTIQLRIKNPQQADLEQQIIRAIELGRKYQAQVFINDYWQLAIKHGAYG 298
54307328  199 EPFCATDAQQLALYPVVDTAEWVDRLLELGVKTTQLRIKNSQDPQLETQVQQIIAAGNQYQAQVFVNDYWQLAIKHQAYG 278
229606621 197 RAFPTIDKAKFNLYPVVDDVNWIEHLLKLGVRTVQLRIKDPKQGDLEAQIIRAIALGREFNAQVFINDHWQLAIKHQAYG 276
147674784 197 RAFPTIDKAKFNLYPVVDDVNWIEHLLKLGVRTVQLRIKDPKQGDLEAQIIRAIALGREFNAQVFINDHWQLAIKHQAYG 276
227080298 197 RAFPTIDKAKFNLYPVVDDVNWIEHLLKLGVRTVQLRIKDPKQGDLEAQIIRAIALGREFNAQVFINDHWQLAIKHQAYG 276
156972706 219 VSFPTLTKQSLGLYPVVDDVAWIERLLPLGINTIQLRIKNLQQADLEQQIIRAIELGRQYQAQVFINDYWQLAIKHCAYG 298
28899800  218 VNFPHLSKQSLGLYPVVDDVSWIERLLPLGINTIQLRIKDPYQPDLEQQIARAIELGRQYDAQVFINDYWQLAIKHGAFG 297
37681390  205 KAFPRVIAQQLGLYPVVDDVSWIEKLLPLGIKTVQLRIKDPNQVDLEQQIVRAIQLGRDYGAKVYINDYWQLAIQYQAYG 284
27364402  205 KAFPRVIAQQLGLYPVVDDVSWIEKLLPLGIKTVQLRIKDPNQVDLEQQIVRAIQLGRDYGAKVYINDYWQLAIQYQAYG 284
15640094  197 RAFPTIDKAKFNLYPVVDDVNWIEHLLKLGVRTVQLRIKDPKQGDLEAQIIRAIALGREFNAQVFINDHWQLAIKHQAYG 276
218710983 199 LSFPELSKSSLGLYPVVDDVEWIERLLKLGINTVQLRIKNPLQADLEQQVARSIELGREHNAQVFINDYWQLALKHDAFG 278
262392847 299 VHLGQEDIEESHLAQLTKAGIRLGLSTHGYYELLRIVQIHPSYIALGHIFPTTTKQMPSKPQGLVRLALYQKLIDsipyg 378
54307328  279 VHLGQEDLETADLVAIQQAGLRIGLSTHGYYEILRAVEFSPSYIALGHIFPTTTKEMPSKPQGLNRLALYQKLIG----- 353
229606621 277 VHLGQEDLTSANLTELLDAGIRLGLSTHGYYELLIAAGIQPSYIALGHIFPTTTKQMPSKPQGLVRLAAYQRLVNqmpy- 355
147674784 277 VHLGQEDLTSANLTELLDAGIRLGLSTHGYYELLIAAGIQPSYIALGHIFPTTTKQMPSKPQGLVRLAAYQRLVNqmph- 355
227080298 277 VHLGQEDLTSANLTELLDAGIRLGLSTHGYYELLIAAGIQPSYIALGHIFPTTTKQMPSKPQGLVRLAAYQRLVNqmpy- 355
156972706 299 VHLGQEDIEESNLAQLTKAGIRLGLSTHGYYELLRIVQIHPSYIALGHIFPTTTKQMPSKPQGLVRLELYQKLIDsipyt 378
28899800  298 VHLGQEDIEDSNLSQLSTAGICLGLSTHGYYELLRIVQINPSYIALGHIFSTTTKQMPSKPQGLVRLALYQKLNDsipy- 376
37681390  285 VHLGQEDLQVADLAALTNAGIALGLSTHGYYELLRIVQLQPSYIALGHIFPTTTKQMPSLPQGLVRLKLYQQLIDtipy- 363
27364402  285 VHLGQEDLQVADLAALTNAGIALGLSTHGYYELLRIVQLQPSYIALGHIFPTTTKQMPSLPQGLVRLKLYQQLIDtipy- 363
15640094  277 VHLGQEDLTSANLTELLDAGIRLGLSTHGYYELLIAAGIQPSYIALGHIFPTTTKQMPSKPQGLVRLAAYQRLVNqmpy- 355
218710983 279 VHLGQEDIEESNLSQLSRAGIKIGLSTHGYYELLRIVQINPSYIALGHIFPTTTKQMPSKPQGLVRLSLYQQLIDtipy- 357
262392847 379 ntesvflpakyktvsdyvLGFPTVAIGGIDQSNADQVWQTGVSSLAVVRAITLAESPQSVIEffa-----qlmKERQLTF 453
54307328  354 ------------------DTFPTVAIGGIDLPRAEKVWRTGVSSVAVVRAITEASDPAMAVD-----------AFNQLLV 404
229606621 356 ---------------qgqHGIPTVAIGGIDCRNIRDVLDCGVTAVAVVRAITESPDPSLAVQalssafadfvdAEYKLMP 420
147674784 356 ---------------qgqHGIPTVAIGGIDCRNIRDVLDCGVTAVAVVRAITESPDPSLAVQalssafadfvdAEYKLMP 420
227080298 356 ---------------qgqHGIPTVAIGGIDCRNIRDVLDCGVTAVAVVRAITESPDPSLAVQalssafadfvdAEYKLMP 420
156972706 379 nteaafrpakgkagsdyvLGFPTVAIGGIDQSNADQVWQTGVSSLAVVRAITLAESPQSVIEffa-----qlmNERQLTF 453
28899800  377 ---------------gesVGYPTVAIGGIDQSNAEQVWQCGVSSLAVVRAITLSESPKQVIEffd-----qlmNTTSTSL 436
37681390  364 --------------desiTGVPTVAIGGIDQSNAATVWQCGVSSLAVVRAITLAKDVKAVIEyfk-----qvmAPNTTLL 424
27364402  364 --------------desiTGVPTVAIGGIDQSNAATVWQCGVSSLAVVRAITLAKDVKAVIEyfk-----qvmAPNTTLL 424
15640094  356 ---------------qgqHGIPTVAIGGIDCRNIRDVLDCGVTAVAVVRAITESPDPSLAVQalssafadfvdAEYKLMP 420
218710983 358 --------------tdqlTGYPTVAIGGIDQSKAEQVWECGVSSLAVVRAITLAEDPQKVIEffe-----klmAPKSPIL 418
262392847 454 TDQNSELAHSKRGEHAHG 471
54307328  405 RPEFPDAINEKITDRIDA 422
229606621 421 ASESCEPLSYLAMEVADA 438
147674784 421 ASESCEPLSYLAMEVADA 438
227080298 421 ASESCEPLSYLAMEVADA 438
156972706 454 TDQNCELAHNKRGEHAYG 471
28899800  437 VMEDYRAY---------- 444
37681390  425 RLDSVSTHSLEPTSEANH 442
27364402  425 RLDSVSTHSLEPTSEANH 442
15640094  421 ASESCEPLSYLAMEVADA 438
218710983 419 KEEVMQEPSYAE------ 430
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