Conserved Protein Domain Family
secD

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PRK05812: secD 
preprotein translocase subunit SecD; Reviewed
Links
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Statistics
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PSSM-Id: 235615
Aligned: 587 rows
Threshold Bit Score: 310.233
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
294507853   6 FKVGLTIFFVGLCGFYLF--PSVqnlyvsykmnnmpeeerveYREDNRQWLeqvDASSL-NLGLDLQGGMHVTLEVEIGN 82 
28493238   14 SLGILAVVVLLLLSLDIW--QVFfs----------------------------gSTFLP-KLALDLEGGTQIVLRAKSAE 62 
28572648    1 MVVLLLLSLDIWQVFFSG--STFl-----------------------------------pKLALDLEGGTQIVLRAKAAE 43 
148272993  11 ARRKLIWLLVIIGLLAGgnaas---------------------------vafsnGSWSP-KLALDLEGGTQIILAPQLDG 62 
163840739  29 RKVILWLGALTVVMALLLtgGSL--------------------------WWgas---wapKLALDLEGGTQMILAPKVDG 79 
170781151  15 LIWLLVIIGILAGGNAAS--VAFs-----------------------------nGSWTP-KLALDLEGGTQIILAPQLDG 62 
220912783  11 LRVLVWLGVIIAALTAVLagGTV---------------------AGQASWSp--------KLALDLEGGTQMILAPKVEG 61 
50954750    1 ---MVLLWTLTAGVLFSN--ATW-----------------------------------LpKLALDLEGGTQIILAPQVSN 40 
116670846   6 PKNSALRVLVWLGVILAVmtav----------------laggSISGQASWAp--------KLALDLEGGTQMILAPKVEG 61 
119963786  14 LTWLGAIFVVLTAVLAGG------------------------VVTGNASWAp--------KLALDLEGGTQMILAPRVEG 61 
294507853  83 LlnqlavnkdeafqqalrtaeqraeeenvsvveafveefeaenpdgrlsryfrnqgeditrrssndevqeyLQGQADTAV 162
28493238   63 ------------------------------------------------------------------------KEITSEQL 70 
28572648   44 ------------------------------------------------------------------------KEITSEQL 51 
148272993  63 A----------------------------------------------------------------------SSGPTSEQL 72 
163840739  80 G-----------------------------------------------------------------------ASINDDQL 88 
170781151  63 A----------------------------------------------------------------------SSGPTSEQL 72 
220912783  62 G-----------------------------------------------------------------------SDINEEQL 70 
50954750   41 G-----------------------------------------------------------------------AAVQQQQL 49 
116670846  62 G-----------------------------------------------------------------------SDINEDQL 70 
119963786  62 S-----------------------------------------------------------------------SEINEEQL 70 
294507853 163 QNGIQVVRNRVNQYGVTEPSIQRQGDERIVVELPGVSDRERVRDLLESASQLTFHLManpqqlgesvqrmi-eyyeptae 241
28493238   71 QQAVAIIRNRVDSSGISEAEISVQGSTNISVSIPGT-PSKEVYDRIRSSSKMDMRAVlltkpi----------------- 132
28572648   52 QQAVAIIRNRVDSSGISEAEISVQGSTNISVSIPGT-PSQEVYDRIRSSSKMDMRAVlltkpiqhaamnegsthagstas 130
148272993  73 AQAVSIIRQRVDASGVSEAEITTQGGSNIVVSLPGE-PDAATMQRLQSSAKLELRPVligaa------------------ 133
163840739  89 NQAISIIRQRVDNTGVSEAQISTSGS-NVVVALPG-EVKPETRDLIKASANMNFRSV----------------------- 143
170781151  73 AQAVSIIRQRVDASGVSEAEITTQGGSNIVVSLPGE-PDAATMQRLQSSAKLELRPVliga------------------- 132
220912783  71 NQAVAIIRQRVDGSGVAEAEISTQSGRNVVVSLPGT-PSTATRDLIQASADMNFRPV----------------------- 126
50954750   50 DQAVSIIRQRIDASGVSEAQISTEGSRNIVVSLPGK-PDEETLDRVKSSARLDFRPVlvag------------------- 109
116670846  71 NQAVAIIRQRVDGSGVAEAEISTQSGRNVVVSLPGT-PSKETRALIQASADMNFRPV----------------------- 126
119963786  71 NQAVAIIRQRVDGSGVAEAEISTQSGRNVVVSLPGT-PSKETRDLIQASADMNFRPV----------------------- 126
294507853 242 dsariAEAQAadtaamEASTDTSGVTEGTELAASsgqeasggqqqgtaltepgesaqtgpqnsllaamqpmpgqeqpiig 321
28493238  133 qhaamNEGSThagstaSAAIGDKNATRGSPKSSEhr-------------------------------------------- 168
28572648  131 aaigdKNATRgspkssEHRKNIPKTPHDTSGMIPsp-------------------------------------------- 166
148272993 134 -gtasVAATPtptptdGSAPADGSTPAAETPAAE---------------------------------------------- 166
163840739 144 -----IAAAPgtptapDKLTPEDQLPKPTAAPTN---------------------------------------------- 172
170781151 133 --agtASVAPtptptdGSAPADGTTPTDGSTPAAea-------------------------------------------- 166
220912783 127 -----LLNGAgavvpeESRAPEDQLPKPTAAPANss-------------------------------------------- 157
50954750  110 --gptNEVVGadgkstPAPTPAPDLLSTPTATPKn--------------------------------------------- 142
116670846 127 -----LQAGPgaavpvESQTPEDKLPKPTAAPANss-------------------------------------------- 157
119963786 127 -----ITYGDpaavpaEQRTPDDQLPKPTAEPANas-------------------------------------------- 157
294507853 322 rafasdtsrvnellqdpsvQnmLPPgiepmwtaspvl-----------------ttedgreafhllAVRA---------- 374
28493238  169 -----------------knIpkTPHdtsgmipsp-----------------------rpkngsdmaWITKywrdrfdshn 208
28572648  167 ------------------rPknGSDmawitkywrdrfdshnckdnagdstpdnlplvvcdqygttkYLLG---------- 218
148272993 167 -------------------AtpDPStlsdeptae-----------------------ptgpsdvswVTPRlqaefaaydc 204
163840739 173 -------------------GsdQNWvdaalykefesyscvtpitepdpqqdpakpsvacdpgtgykYILG---------- 223
170781151 167 -----------------paAtpDPStlsdeptae-----------------------ptgpsdvswVTPRlqaefaaydc 206
220912783 158 -----------------diNwiTPEiyrefealdcdnasaekaersdptkplvtcepatdtspaikYILG---------- 210
50954750  143 ------------------gSdlAWVtpklqaefnafecksadhqdlssaptdqplitcddggtvkyLLG----------- 193
116670846 158 -----------------dvNwvTPEvykkfetldcdnpsqdkqersdpakplvtcepatatspaikYILG---------- 210
119963786 158 -----------------diNwvTADivkefealdcvnpspekrersdpakplvtceaataqtpaikYILG---------- 210
294507853 375 -------------------------------EPELTGEVVTEA-S---VQF--D----RQt-----NEPKVSITMNSDGA 408
28493238  209 ckdnagdstp--dnlplvvcdqygttkyllgPVEVSGTDISRA-VadpVSShfAg---AS------IGWGVTITFNAHGG 276
28572648  219 -------------------------------PVEVSGTDISRAvA--------Dpv-sSHfag-asIGWGVTITFNAHGG 257
148272993 205 atapendgqaapadraiiacsddgaakyvlgPVEVDGSTISDA-TsglQQS--Sqg-vST------GTWSVNLVFDGDGT 274
163840739 224 -------------------------------PVEVAGKEITDA-S---YGL--Q----QGaqgtttNKWAVNLAFNQDGA 262
170781151 207 atapesdgqaapadraiiacsddgaakyvlgPVEVDGSTISDA-T---SGLq-Q----SSqgv-stGTWSVNLVFDGDGT 276
220912783 211 -------------------------------PVEVKGSNIVTS-S---FQL--Q----QGaqgavtNDWAVNIQFNDEGT 249
50954750  194 -------------------------------PVEVKGQNIKDA-S---AGLvqSsqgvTT------GQWAVNIVFDGTGT 232
116670846 211 -------------------------------PVEVKGSNIKSS-S---FQL--Q----QGaqgavtNEWAVNIQFDEAGT 249
119963786 211 -------------------------------PVEVRGQDISDStF---SQV-------QGaqgsvtNSWGVNIVFNADAT 249
294507853 409 RRWDRITAANI-------G----------NRVSIVL---------------DDIVYSSPNIQSRISGGRTEITGLESRQE 456
28493238  277 EKFKDVSNRLI-------Slaa-----prNQFAAVL---------------DGVVITAPEVRGV--TSNPQITGNFNQTT 327
28572648  258 EKFKDVSNRLI-------Slaa-----prNQFAAVL---------------DGVVITAPEVRGV--TSNPQITGNFNQTT 308
148272993 275 KQFGDMSTRLItle------------sprNQFAFVL---------------DNEVISAPVTQGVVTNGKPSITGNFTQES 327
163840739 263 TKFKEVTTRLN-------GfylanqqdpkAQFAIVL---------------DGKIVSAPSSQAVITDGKSQITGNFTETS 320
170781151 277 KQFGDMSTRLI-------Tles-----prNQFAFVL---------------DNEVISAPVTQGVVTNGKPSITGNFTQES 329
220912783 250 AKFKEVTERLNqfyvaagGesgt---dpkAQFAIVL---------------DDQVISAPRALAVITDGRPQITGGFTEQT 311
50954750  233 KQFADVTTRLV-------Gltg-----sqNQFAIVL---------------DGKVISAPTTQSAITDGKPQITGNFTESS 285
116670846 250 AKFKEVTERLYqffvaagGesgn---dpkAQFAIVL---------------DDQVISAPRSLAVITDGRPQITGGFTEDT 311
119963786 250 AKFKAVTERLN------------------QFYAAAQlqgsddpksqfaivlDDKVISAPRALAVITDGKPQITGNFTQAS 311
294507853 457 AQDIVTVLQSGRLQTDLNIISERTVGPSLGEESTRAGFISVVAGFLLVVLFMIMYYRTAGVVADIALLLNLILIMGILAG 536
28493238  328 ATALASQLSFGSLPVSFEVQSSENISATLGSSQLQSGILAGILGMILVVVYSLFQYRLLGLLTVSSLICSAIVTYLVITF 407
28572648  309 ATALASQLSFGSLPVSFEVQSSENISATLGSSQLQSGILAGILGMILVVVYSLFQYRLLGLLTVSSLICSAIVTYLVITF 388
148272993 328 AKALADQLKFGALPLSFTLQSSDVISATLGSSQLTSGLIAGLIGLVLVVLYSLVQYRALGMVTIASLVIAAVITYLLITL 407
163840739 321 AKSLSDKLKFGALPISFDIQSEEQISATLGTQQLEMGLLAGLIGLALVVVYSLFQYRALGFVTVASLVVAGVLTYLAIAV 400
170781151 330 AKALADQLKFGALPLSFTLQSSDVISATLGSSQLTSGLIAGLIGLVLVVLYSLVQYRALGMVTIASLVIAAVITYLLITL 409
220912783 312 AKALSDQLRFGALPISFEIQSEQQISATLGGEQLRMGLLAGLIGLLLVVVYSLFQYRALGFVTIASLVVAGVLTYLAIAI 391
50954750  286 AKALADQLKFGALPFSFKVQSQDTISATLGSAQLLAGLIAGLIGLLLVAIYTFFQYRLLAFVTIFSLVVAGVLTWLTISL 365
116670846 312 AKALSDQLRFGALPISFEIQSEQQISATLGGEQLRMGLLAGVIGLLLVVVYSLFQYRALGFVTIFSLVVAGALTYLAIAI 391
119963786 312 AKALSDQLRYGALPISFEIQSQEQISATLGGDQLRLGLLAGMIGLLLVVVYSLFQYRALGLVTIASLVVAGVLTYLAIAI 391
294507853 537 FG----ATLTLPGIAGIVLTIGMAVDANVLVYDRVREEQATGKTLRAAINAGYEQSLSAILDANITTFFVGVILYSFGVG 612
28493238  408 LSwqngYRLSLAGVAGLIVAIGITADSFIVYFERVKDELREGRDIVRAVDRGWSRALRTICASDAVNFLAAIVLFLVAVG 487
28572648  389 LSwqngYRLSLAGVAGLIVAIGITADSFIVYFERVKDELREGRDIVRAVDRGWSRALRTICASDAVNFLAAIVLFLVAVG 468
148272993 408 LSwregYRLSLAGVAGLIVAIGITADSFIVYFERIKDELRDGRGLVSSVEQGWKRALRTIIASDTVNFLAAAVLFILAVG 487
163840739 401 LGwsqnYRLSLAGVAGLIVAIGQTADSFIVYFERIRDELREGRGLVAAVENGWKRAKRTVLASKAVNLLAAVVLYFVAVG 480
170781151 410 LSwregYRLSLAGVAGLIVAIGITADSFIVYFERIKDELRDGRGLVSSVEQGWKRALRTIIASDTVNFLAAAVLFILAVG 489
220912783 392 LGwtenYRLSLAGVAGIIVAIGQTADSFIVYFERIRDELREGRGLVSAVENGWKRAKRTVLASKAVNLLAALVLYFVAVG 471
50954750  366 LSwhydYRLSLAGVAGLIVAIGFTADSFIVYFERIRDELRDGRSLESAVEAGWGRARRTIYASKATNLLAAIVLYILAAA 445
116670846 392 LGwtenYRLSLAGVAGLIVAIGQTADSFIVYFERIRDELREGRGLVSAVENGWKRAKRTVLASKAVNLLAALVLYFVAVG 471
119963786 392 LGwtenYRLSLAGVAGLIVAIGQTADSFIVYFERIRDELREGRGLVSAVENGWKRAKRTVLASKAVNLLAAVVLYFVAVG 471
294507853 613 PIKGFAVTLMAGILASLFTAIIVTRIIFD-------YM------------------------------------------ 643
28493238  488 SVKGFAFTLGLTTLVDLLVVVFFTHPVLQylshssfFTrk---------------------------------------- 527
28572648  469 SVKGFAFTLGLTTLVDLLVVVFFTHPVLQylshssfFTrk---------------------------------------- 508
148272993 488 NVKGFALTLGLTTIIDLIVVSLFTHPILQl------LAnrrffaeghrmsgldpral------------gavyrgratfr 549
163840739 481 NVRGFAFTLGLTAIADLIVVFMFTHPTLQlla-trkFFse---------------------------------------- 519
170781151 490 NVKGFALTLGLTTIIDLIVVSLFTHPILQlla-nrrFFae---------------------------------------- 528
220912783 472 NVRGFAFTLGLTAIADLIVVFMFTHPTLQ-------LLartrf------------------------------------- 507
50954750  446 NVRGFAFTLGLTTIIDVIVVLLFTHPTLQl------LAktaffseghtlsgldpqalgavyrgaaqfrspalsvnrgkaa 519
116670846 472 NVRGFAFTLGLTAIADLIVVFMFTHPTLQ-------LLartkf------------------------------------- 507
119963786 472 NVRGFAFTLGLTAVADLIVVFMFTHPTLQ-------LLartkf------------------------------------- 507
294507853 644 --------VEDR--------RMQV 651
28493238  528 -------ySGLNvks--avyRGRL 542
28572648  509 -------ySGLNvks--avyRGRL 523
148272993 550 tptatagrGAAAake--aarRQTI 571
163840739 520 -------gHRFSglspdrlgAVPL 536
170781151 529 -------gHRMSgld--praLGAV 543
220912783 508 ----fgegHRFSgldpkrlgAVPL 527
50954750  520 rssneaarRQTIaer--kaaELTA 541
116670846 508 ----fgegHKFSgldpkrlgAVPL 527
119963786 508 ----fgegHRFSglspdrlgAVPL 527
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