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NADB_Rossmann: Rossmann-fold NAD(P)(+)-binding proteins
A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The N...
View in Cn3D
lipocalin_FABP: lipocalin/cytosolic fatty acid-binding protein family
Lipocalins are diverse, mainly low molecular weight extracellular proteins that bind principally sma...
7tm_GPCRs: seven-transmembrane G protein-coupled receptor superfamily
This hierarchical evolutionary model represents the seven-transmembrane (7TM) receptors, often refer...
AFD_class_I: Adenylate forming domain, Class I superfamily
This family includes acyl- and aryl-CoA ligases, as well as the adenylation domain of nonribosomal p...
PLDc_SF: Catalytic domain of phospholipase D superfamily proteins
Catalytic domain of phospholipase D (PLD) superfamily proteins. The PLD superfamily is composed of a...
MPP_superfamily: metallophosphatase superfamily, metallophosphatase domain
Metallophosphatases (MPPs), also known as metallophosphoesterases, phosphodiesterases (PDEs), binucl...
GH43_62_32_68_117_130: Glycosyl hydrolase families: GH43, GH62, GH32, GH68, GH117, CH130
Members of the glycosyl hydrolase families 32, 43, 62, 68, 117 and 130 (GH32, GH43, GH62, GH68, GH11...
View in Cn3D ProteinSuperfamily MembersPubMed
HAD_like: Haloacid Dehalogenase-like Hydrolases
The haloacid dehalogenase (HAD) superfamily includes carbon and phosphorus hydrolases such as 2-halo...
P-loop_NTPase: P-loop containing Nucleoside Triphosphate Hydrolases
Members of the P-loop NTPase domain superfamily are characterized by a conserved nucleotide phosphat...
Zinc_peptidase_like: Zinc peptidases M18, M20, M28, and M42
Zinc peptidases play vital roles in metabolic and signaling pathways throughout all kingdoms of life...
C_NRPS-like: Condensation domain of nonribosomal peptide synthetases (NRPSs)
Condensation (C) domains of nonribosomal peptide synthetases (NRPSs) catalyze peptide bond formation...
cytochrome_P450: cytochrome P450 (CYP) superfamily
Cytochrome P450 (P450, CYP) is a large superfamily of heme-containing proteins that catalyze a varie...
AmyAc_family: Alpha amylase catalytic domain family
The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majorit...
Periplasmic_Binding_Protein_Type_2: Type 2 periplasmic binding fold superfamily
This evolutionary model and hierarchy represent the ligand-binding domains found in solute binding p...
GT29: glycosyltransferase family 29
Glycosyltransferase family 29 members (also called sialyltransferases) are enzymes that transfer sia...
Periplasmic_Binding_Protein_type1: Type 1 periplasmic binding fold superfamily
Type 1 periplasmic binding fold superfamily. This model and hierarchy represent the ligand binding d...
TIM: TIM-like beta/alpha barrel domains
A large family of domains similar to triose phosphate isomerase (TIM) which, in general, share an ei...
LGIC_ECD: extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
This superfamily contains the extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion chan...
MFS: Major Facilitator Superfamily
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that ...
RING_Ubox: RING finger (Really Interesting New Gene) domain and U-box domain superfamily
The RING finger is a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc...
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