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RING_Ubox: RING finger (Really Interesting New Gene) domain and U-box domain superfamily
The RING finger is a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc...
View in Cn3D
TGF_beta_SF: transforming growth factor beta (TGF-beta) like domain found in TGF-beta superfamily
TGF-beta superfamily consists of a large group of cell regulatory proteins, such as TFG-betas, Nodal...
7tm_GPCRs: seven-transmembrane G protein-coupled receptor superfamily
This hierarchical evolutionary model represents the seven-transmembrane (7TM) receptors, often refer...
lipocalin_FABP: lipocalin/cytosolic fatty acid-binding protein family
Lipocalins are diverse, mainly low molecular weight extracellular proteins that bind principally sma...
TGF_beta_LEFTY1_2: transforming growth factor beta (TGF-beta) like domain found in left-right determination factor 1 (lefty-1), factor 2 (lefty-2) and similar proteins
Lefty-1, also termed left-right determination factor B, or protein lefty-B, is required for left-rig...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
lipocalin_beta-LG-like: beta-lactoglobulin and similar proteins
Beta-Lactoglobulin (beta-LG) is the major whey protein of ruminant species and present in the milk o...
DEAD-like_helicase_N: N-terminal helicase domain of the DEAD-box helicase superfamily
The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or ...
TNFRSF: Tumor necrosis factor receptor superfamily (TNFRSF)
Members of TNFR superfamily (TNFRSF) interactions with TNF superfamily (TNFSF) ligands (TNFL) contro...
PKc_like: Protein Kinases, catalytic domain
The protein kinase superfamily is mainly composed of the catalytic domains of serine/threonine-speci...
SPFH_like: core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
This model summarizes proteins similar to stomatin, prohibitin, flotillin, HflK/C (SPFH) and podocin...
PH-like: Pleckstrin homology-like domain
The PH-like family includes the PH domain, both the Shc-like and IRS-like PTB domains, the ran-bindi...
RELM: resistin-like molecule (RELM) hormone family
RELMs, secreted proteins with roles including insulin resistance and the activation of inflammatory ...
SPRY: SPRY domain
SPRY domains, first identified in the SP1A kinase of Dictyostelium and rabbit Ryanodine receptor (he...
VHS_ENTH_ANTH: VHS, ENTH and ANTH domain superfamily
This superfamily is composed of proteins containing a VHS, CID, ENTH, or ANTH domain. The VHS domain...
alpha-crystallin-Hsps_p23-like: alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins
The alpha-crystallin-Hsps_p23-like superfamily includes the alpha-crystallin domain (ACD) of alpha-c...
Bbox_SF: B-box-type zinc finger superfamily
The B-box-type zinc finger is a short zinc binding domain of around 40 amino acid residues in length...
Arginase_HDAC: Arginase-like and histone-like hydrolases
Arginase-like/histone-like hydrolase superfamily includes metal-dependent enzymes that belong to Arg...
View in Cn3D ProteinSuperfamily MembersPubMed
RING-H2_RNF43: RING finger, H2 subclass, found in RING finger protein 43 (RNF43) and similar proteins
RNF43 is a transmembrane E3 ubiquitin-protein ligase that plays an important role in frizzled (FZD)-...
mRING-HC-C3HC5_CGRF1: Modified RING finger, HC subclass (C3HC5-type), found in cell growth regulator with RING finger domain protein 1 (CGRRF1) and similar proteins
CGRRF1, also known as cell growth regulatory gene 19 protein (CGR19) or RING finger protein 197 (RNF...
mRING-HC-C3HC5_CGRF1-like: Modified RING finger, HC subclass (C3HC5-type), found in RING finger proteins, RNF26, RNF197 (CGRRF1), RNF156 (MGRN1), RNF157 and similar proteins
This subfamily corresponds to a group of RING finger proteins containing a modified C3HC5-type RING-...
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