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Sir4_CC_C: C-terminal coiled coil domain found in Saccharomyces cerevisiae silent information regulator 4 (Sir4p) and similar proteins
Sir4p is a regulatory protein that plays important roles in silent chromatin at telomeric and silent...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
Sir4p-SID_like: The SID domain of Saccharomyces cerevisiae silent information regulator 4, a Sir2p interaction domain; and related domains
Saccharomyces cerevisiae Sir2p, Sir3p, and Sir4p form a heterotrimeric complex which binds chromatin...
View in Cn3D ProteinSuperfamily MembersPubMed
Ubl_SLD2_Esc2_like: SUMO-like domain 2 (SLD2), structurally similar to a beta-grasp ubiquitin-like fold, found in Saccharomyces cerevisiae establishes silent chromatin protein 2 (Esc2p) and similar proteins
Protein Esc2p belongs to the eukaryotic-specific Rad60-Esc2-Nip45 (RENi) protein family, whose membe...
SIR2
SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze N...
CD_CSD: CHROMO (CHRromatin Organization Modifier) domains and chromo shadow domains
Members of this group are chromodomains or chromo shadow domains; these are SH3-fold-beta-barrel dom...
View in Cn3D
BTB_POZ: BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
Proteins in this superfamily are characterized by the presence of a common protein-protein interacti...
CSD_Swi6: chromo shadow domain of chromatin-associated protein Swi6
Chromo shadow domain (CSD) of fission yeast Swi6 protein. Swi6 is a structural and functional homolo...
CD_Swi6_like: chromodomain of fission yeast Swi6, and similar proteins
Fission yeast Swi6 protein is a structural and functional homolog of mammalian HP1 (heterochromatin ...
BTB_POZ_Kv6_KCNG: BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in KCNG/Kv6 subfamily of potassium voltage-gated channels
Voltage-gated potassium (Kv) channels are composed of alpha subunits, which form the actual conducta...
NR_LBD: The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
Ligand-binding domain (LBD) of nuclear receptor (NR): Nuclear receptors form a superfamily of ligan...
Hat1_N: Histone acetyl transferase HAT1 N-terminus
This domain is the N-terminal half of the structure of histone acetyl transferase HAT1. It is often ...
HIRA_B: HIRA B motif
The HirA B (Histone regulatory homolog A binding) motif is the essential binding interface between H...
rap1_RCT: C-terminal domain of RAP1 recruits proteins to telomeres
The RAP1 (repressor activator protein 1) C-terminal domain (RCT) mediates interactions with other pr...
HlyE-like: alpha pore-forming toxin (alpha-PFT) hemolysin E (HlyE, ClyA or SheA) in Escherichia coli, Salmonella typhi, and Shigella flexneri, and similar proteins
This family of alpha pore-forming toxins (alpha-PFTs) includes hemolysin E (HlyE; also called cytoly...
Rap1_C: TRF2-interacting telomeric protein/Rap1 - C terminal domain
This family of proteins represents the C-terminal domain of the protein Rap-1, which plays a distinc...
Sir1: Sir1, ORC-binding domain
This entry represents the ORC-binding domain of Sir1. Sir1 interacts with the BAH domain of the Orc1...
SIR2: Sir2 family
This region is characteriztic of Silent information regulator 2 (Sir2) proteins, or sirtuins. These ...
View in Cn3D SuperfamilySuperfamily MembersPubMed
SIR4_SID: Sir4 SID domain
This is the Sir2 interaction domain (SID domain) of silent information regulator 4 (Sir4).
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