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7tm_GPCRs: seven-transmembrane G protein-coupled receptor superfamily
This hierarchical evolutionary model represents the seven-transmembrane (7TM) receptors, often refer...
View in Cn3D
RING_Ubox: RING finger (Really Interesting New Gene) domain and U-box domain superfamily
The RING finger is a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc...
SAM_superfamily: SAM (Sterile alpha motif )
SAM (Sterile Alpha Motif) domain is a module consisting of approximately 70 amino acids. This domain...
RRM_SF: RNA recognition motif (RRM) superfamily
RRM, also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant ...
BTB_POZ: BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
Proteins in this superfamily are characterized by the presence of a common protein-protein interacti...
View in Cn3D ProteinSuperfamily MembersPubMed
PHD_SF: PHD finger superfamily
The PHD finger superfamily includes a canonical plant homeodomain (PHD) finger typically characteriz...
Ubl1_cv_Nsp3_N-like: first ubiquitin-like (Ubl) domain located at the N-terminus of coronavirus SARS-CoV non-structural protein 3 (Nsp3) and related proteins
This ubiquitin-like (Ubl) domain (Ubl1) is found at the N-terminus of coronavirus Nsp3, a large mult...
UBA_like_SF: UBA domain-like superfamily
The ubiquitin-associated (UBA) domain-like superfamily contains alpha-helical structural homology ub...
Bbox_SF: B-box-type zinc finger superfamily
The B-box-type zinc finger is a short zinc binding domain of around 40 amino acid residues in length...
HAD_like: Haloacid Dehalogenase-like Hydrolases
The haloacid dehalogenase (HAD) superfamily includes carbon and phosphorus hydrolases such as 2-halo...
alpha-crystallin-Hsps_p23-like: alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins
The alpha-crystallin-Hsps_p23-like superfamily includes the alpha-crystallin domain (ACD) of alpha-c...
Thioredoxin_like: Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
The thioredoxin (TRX)-like superfamily is a large, diverse group of proteins containing a TRX fold. ...
bHLH_SF: basic Helix Loop Helix (bHLH) domain superfamily
bHLH proteins are transcriptional regulators that are found in organisms from yeast to humans. Membe...
BRcat_Rcat_RBR: BRcat (benign-catalytic) and Rcat (required-for-catalysis) domains, part of the RBR (RING1-BRcat-Rcat) domain
The RBR family of RING-type E3 ligases are characterized by containing an RBR (RING1-BRcat-Rcat) dom...
SPRY: SPRY domain
SPRY domains, first identified in the SP1A kinase of Dictyostelium and rabbit Ryanodine receptor (he...
SOCS
SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/...
MFS: Major Facilitator Superfamily
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that ...
RWD_DRWD_ELF-like: RWD, DRWD, and ELF domain family
The family includes the RWD, double-RWD (DRWD), and ELF domains. They belong to the ubiquitin-conjug...
KH-I: K homology (KH) RNA-binding domain, type I
KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal p...
PA
PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of prot...
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