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Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence. Geneva: World Health Organization; 2009.
Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence.
Show detailsThese guidelines were produced by the World Health Organization (WHO), Department of Mental Health and Substance Abuse, in collaboration with the United Nations Office on Drugs and Crime (UNODC) a Guidelines Development Group of technical experts, and in consultation with the International Narcotics Control Board (INCB) secretariat and other WHO departments. WHO also wishes to acknowledge the financial contribution of UNODC and the Joint United Nations Programme on HIV/AIDS (UNAIDS) to this project.
GUIDELINES DEVELOPMENT GROUP
- Marina DavoliCoordinating EditorCochrane Review Group on Drugs and AlcoholDepartment of EpidemiologyOsservatorio Epidemiologico Regione LazioRomaItaly
- Michael FarrellReader/Consultant PsychiatristNational Addiction CentreInstitute of Psychiatry and the Maudsley HospitalLondonUnited Kingdom
- David FiellinAssociate Professor of MedicineYale University School of MedicineUnited States of America
- Li JianhuaDeputy DirectorYunnan Institute for Drug AbuseChina
- Ratna MardiatiPsychiatristDirectorate General for Medical CareJakartaIndonesia
- Richard MattickDirectorNational Drug and Alcohol Research CentreUniversity of new South WalesSydneyAustralia
- Elena Medina-MoraDirectorEpidemiology and Psychosocial ResearchNational Institute of PsychiatryMexico
- Fred OwitiConsultant PsychiatristArrow Medical CentreNairobiKenya
- Afarin Rahimi-MovagharIranian national Center for Addiction StudiesTehran University of Medical SciencesTehranIran
- Rajat RayChiefNational Drug Dependence Treatment CentreAll India Institute of Medical SciencesNew DelhiIndia
- Anthony J SmithEmeritus ProfessorClinical PharmacologyNewcastle Mater HospitalAustralia
- Emilis SubataDirectorVilnius Center for Addictive DisordersLithuania
- Ambros UchtenhagenPresidentResearch Institute for Public Health and AddictionZurichSwitzerland
OBSERVERS
Council of Europe
- Gabrielle Welle-StrandSenior AdviserNorwegian Directorate for Health and Social AffairsNorway
International Narcotics Control Board Secretariat
- Pavel PachtaChief, narcotics Control and estimates SectionViennaAustria
- Carmen Selva-BartolomeChief, Psychotropics Control Section (until September 2007)ViennaAustria
- Margarethe EhrenfeldnerChief, Psychotropics Control Section (as of 1 October 2007)ViennaAustria
UNITED NATIONS OFFICE ON DRUGS AND CRIME SECRETARIAT
- Juana Tomas-RosselloDrug Abuse Treatment Adviser, Global Challenges SectionViennaAustria
WORLD HEALTH ORGANIZATION SECRETARIAT
Department of Mental Health and Substance Abuse
- Vladimir PoznyakCo-ordinator
- Nicolas ClarkMedical Officer
- Hannu AlhoTemporary Advisor (seconded from the national Public Health Institute of Finland [KTL])
Department of HIV
- Annette VersterTechnical Officer
Department of Health Systems Financing
- Dan ChisholmEconomist
Department of Medicines Policy and Standards
- Sue HillMedical Officer
- Nicola MagriniMedical Officer
Other contributors
WHO would also like to acknowledge the contribution made by the following individuals in the development of background materials and peer review:
- Laura Amato, Department of epidemiology, Azienda Sanitaria locale “E”, Rome, Italy
- Mike Ashton, Drug and Alcohol Findings, United Kingdom
- Anna Maria Bargagli, Department of epidemiology, Azienda Sanitaria locale “E”, Rome, Italy
- James Bell, national Addiction Centre, London, United Kingdom
- Adrian Carter, Queensland Brain Institute, University of Queensland, Australia
- Zhang Cunmin, Yunnan Institute for Drug Abuse, Kunming, Yunnan, China
- Chris Doran, national Drug & Alcohol Research Centre, University of new South Wales, Australia
- Colin Drummond, St George's, University of London, United Kingdom
- Ralph Edwards, Director, Uppsala Monitoring Centre, Sweden
- Gabriele Fischer, Medical University of Vienna, Austria
- Andy Gray, University of KwaZulu-Natal, Durban, South Africa
- Wayne Hall, School of Population Health, University of Queensland, Australia
- S Kattimani, national Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India
- Nina Kopf, Department of Psychiatry, Medical University of Vienna, Austria
- T Ladjevic, Research Institute for Public Health and Addiction. Zurich University, Switzerland
- Lisa Marsch, Center for Drug Use and HIV Research, national Development and Research Institutes, New York, USA
- Silvia Minozzi, Department of epidemiology, Azienda Sanitaria locale “E”, Rome, Italy
- Lubomir Okruhlica, Institute for Drug Dependencies, Centre for Treatment of Drug Dependencies, Bratislava, Slovak Republic
- Katherine Perryman, St George's, University of London, United Kingdom
- Carlo Perucci, Department of epidemiology, Azienda Sanitaria locale “E”, Rome, Italy
- Li Peikai, Yunnan Institute for Drug Abuse, Kunming, Yunnan, China
- Jurgen Rehm, Research Institute for Public Health and Addiction. Zurich University, Centre for Addiction and Mental Health, Toronto, Canada
- H K Sharma, national Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India
- Simona Vecchi, Department of epidemiology, Azienda Sanitaria locale “E”, Rome, Italy
Declaration of interests of the guidelines development group
Michael Farrell reported being a member of the National Guidelines Group on Substance Dependence in the United Kingdom, receiving travel support and expenses for speaking at meetings from Reckitt Benckiser and Schering Plough (value <$1000 each occasion), and in collaboration with the University of Adelaide and the University of California, Los Angeles, receiving an unrestricted educational grant from Reckitt Benckiser (through the University of Adelaide) to organize a meeting on substance dependence in South East Asia, with no personal payments from the grant.
David Fiellin reported providing expert opinion at a congressional press conference related to treatment of substance dependence, and providing an expert review of methadone, buprenorphine and buprenorphine/naloxone for the United States Centre for Substance Abuse treatment, with no honorariums.
Richard Mattick reported providing advice and public statements on treatment of substance dependence in his role as Director of the National Drug and Alcohol Research Centre, receiving research support to his research unit as an untied educational grant from Reckitt Benckiser (value approximately $AU400 000 over 3 years), but without personal payment, and receiving research support to his research unit from the Australian National Health and Medical Research Council for research on substance dependence (value approximately $AU150 000).
Rajat Ray reported being a member of the Indian Expert Group for the Ministry of Health, India, on opioid substitution treatment and presenting a scientific paper on the topic in 2005, receiving funding for his research unit from Rusan Pharmaceuticals (value $US350 000) for research related to buprenorphine, with no personal payments.
Ambrose Uchtenhagen reported receiving funding for a literature review at least 3 years ago from Schering Plough.
Marina Davoli, Ratna Mardiati, Afarin Rahimi Movaghar, Fred Owiti, Emilis Subata, Anthony Smith, and Gabrielle Welle-Strand reported no conflict of interest.
Organizations providing feedback on the draft guidelines
- WHO Regional Offices
- WHO Collaborating Centres
- ♦
Addiction Research Institute, Zurich, Switzerland
- ♦
Centre for Addiction and Mental Health, Toronto, Canada
- ♦
College on Problems of Drug Dependence, Vermont, Unites States
- ♦
Drug and Alcohol Services Council, Adelaide, Australia
- ♦
Institute of Health Science Research, Bangkok, Thailand
- ♦
Mental Health Institute, Hunan, China
- ♦
National Drug Research Institute, Perth, Australia
- Other organizations
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American Association for the Treatment of Opioid Dependence
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American College of Neuropsychopharmacology
- ♦
American Society of Addiction Medicine
- ♦
International Harm Reduction Association
- ♦
International Center for Advancement of Addiction Treatment (ICAAT)
- ♦
National Alliance of Methadone Advocates, New York, United States
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National Institute on Drug Abuse, United States
- ♦
National Institute for Health and Clinical Excellence (NICE), United Kingdom
- ♦
Quest for Quality, the Netherlands
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Service d'Abus de Substances, Département de Psychiatrie, Genève
- ♦
South African National Council on Alcohol and Drug Dependence
- ♦
Turning Point Alcohol & Drug Centre, Melbourne, Australia
- ♦
World Psychiatric Association
- ♦
South African National Council on Alcohol and Drug Dependence
- ♦
Turning Point Alcohol & Drug Centre, Melbourne, Australia
- ♦
World Psychiatric Association
- Acknowledgements - Guidelines for the Psychosocially Assisted Pharmacological Tr...Acknowledgements - Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence
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