This collection of clinical guidelines is designed to assist physicians in providing optimal patient care cost-effectively. Each guideline addresses a specific medical condition, addressing important clinical decisions and practical considerations and actions in either the inpatient and ambulatory care setting. The guidelines are developed through a collaborative process involving multi-specialty teams and consultants. Recommendations are based on best available empirical evidence, other evidence-based guidelines prepared by nationally recognized groups, and expert consensus.

The guidelines should not be construed as including all proper methods of care or excluding other acceptable methods of care reasonably directed to obtaining the same results. The ultimate judgment regarding any specific clinical procedure or treatment must be made by the physician in light of the circumstances presented by the patient.

Contents

• Alcohol Withdrawal in Hospitalized Patients: Michigan Alcohol Withdrawal Severity (MAWS) Protocol
  Staci C Blackburn, Team Lead, Nathan L Haas, Mary Jo Kocan, Winnie Wood, Nathan B Menke, Lisa S Seyfried, Steven B Chinn, Amy VandenBerg, and Scott L Ciarkowski. Clinical Guidelines Oversight: Megan Mack, Dave Wesorick, and April Proudlock.
  Ann Arbor (MI): Michigan Medicine University of Michigan; May 2024.
• Inpatient Diagnosis and Treatment of Catheter-Related Bloodstream Infection
  Ji Hoon Baang, Co-Lead, Kengo Inagaki, Co-Lead, Jerod Nagel, Karthik Ramani, Terri L Stillwell, Megan Mack, and David Wesorick. Clinical Guidelines Oversight: Megan Mack, Dave Wesorick, and April Proudlock.
  Ann Arbor (MI): Michigan Medicine University of Michigan; January 2023.
• Early Recognition and Initial Management of Sepsis in Adult Patients
  Jessie King, Lead, Carol E Chenoweth, Peter C England, Andrew Heiler, Michael T Kenes, Krishnan Raghavendran, Winnie Wood, and Shiwei Zhou. Clinical Guidelines Oversight: Megan Mack, Dave Wesorick, and April Proudlock.
  Ann Arbor (MI): Michigan Medicine University of Michigan; 2023.
• Michigan Medicine Inpatient Diuretic Guideline for Patients with Acute Decompensated Heart Failure
  Matthew C Konerman, Co-Lead, David A Bozaan, Co-Lead, Sarah Adie, Michael Heung, Jessica Guidi, and Adam B Stein. Clinical Guidelines Oversight: Megan Mack, Dave Wesorick, and April Proudlock.
  Ann Arbor (MI): Michigan Medicine University of Michigan; December 2022.
• Care of the Hospitalized Patient with Acute Exacerbation of COPD
  Rommel L. Sagana, Co-Lead, David H. Wesorick, Co-Lead, Brendan T. Byrne, Linda J. Fitzgerald, and Todd E. Georgia. Clinical Guidelines Oversight: Megan Mack, Dave Wesorick, and April Proudlock.
  Ann Arbor (MI): Michigan Medicine University of Michigan; April 2022.
• Family-Centered Rounds
  Courtney Palka, co-lead, Mayya Malakh, co-lead, and Elizabeth Hill. Consultants: Elizabeth Baron, Jaqueline Fisher, Joseph Kohne, Austin Michalski, Rebecca A Pehovic, Katelyn H Roberts, Shatoria Townsend, Roselle Vittorino, and Ashley Wester. Clinical Guidelines Oversight: Megan Mack, Dave Wesorick, and April Proudlock.
  Ann Arbor (MI): Michigan Medicine University of Michigan; March 2022.
• Evaluation and Management of Gallstone-Related Diseases in Non-Pregnant Adults
  Lena M Napolitano, Lead, Hasan B Alam, Ben E Biesterveld, Joseph J Gemmete, Steven L Kronick, Benjamin Pomerantz, William T Repaskey, and Michael David Rice. Inpatient Clinical Guidelines Oversight: Megan R Mack, April Proudlock, and David H Wesorick.
  Ann Arbor (MI): Michigan Medicine University of Michigan; December 2021.
• Inpatient Management of Acute Atrial Fibrillation and Atrial Flutter in Non-Pregnant Hospitalized Adults
  Jeffrey M Rohde, Team Co-Lead, Mohammed Saeed, Team Co-Lead, Geoffrey D Barnes, Sarah Hanigan, Jules Lin, Sadhana Murali, David M Somand, David H Wesorick, and Sarah Adie, Reviewer. Inpatient Clinical Guidelines Oversight: Megan R Mack, David H Wesorick, and April Proudlock.
  Ann Arbor (MI): Michigan Medicine University of Michigan; November 2021.
• Management of Type 2 Diabetes Mellitus
  Caroline R Richardson, Lead, Jeffrey R Borgeson, R Van Harrison, Jennifer A Wyckoff, and Anne S Yoo. Consultants: James E Aikens, Dina H Griauzde, and Monica A Tincopa. Guidelines Oversight: R. Van Harrison, April L. Proudlock, and Karl T. Rew.
  Ann Arbor (MI): Michigan Medicine University of Michigan; October 2021.
• Asthma
  Jeffery D Smith, Lead, Manuel Arteta, Alan P Baptist, R Van Harrison, Scott A Kelley, Valerie A Lindell, Njira L Lugogo, and Jill A Noble. Ambulatory Clinical Guidelines Oversight: Karl T Rew, R Van Harrison, and April L Proudlock.
  Ann Arbor (MI): Michigan Medicine University of Michigan; July 2021.
• Urinary Tract Infection
  Catherine M. Bettcher, Lead, Elizabeth Campbell, Lindsay A. Petty, Karl T. Rew, Jennifer C. Zelnik, and Giulia I. Lane, Consultant. Ambulatory Clinical Guidelines Oversight: R. Van Harrison, April L. Proudlock, and Karl T. Rew.
  Ann Arbor (MI): Michigan Medicine University of Michigan; May 2021.
• Evaluation and Management of Mechanical Small Bowel Obstruction in Adults
  Gary Vercruysse, Co-Lead, Rebecca Busch, Co-Lead, Derek Dimcheff, Co-Lead, Mahmoud Al-Hawary, Richard Saad, F. Jacob Seagull, David Somand, Jill Cherry-Bukowiec, Lauren Wanacata, and Luke Pumiglia.
  Ann Arbor (MI): Michigan Medicine University of Michigan; April 2021.
• Unipolar Depression
  Stephen J. Warnick, Jr, Lead, R. Van Harrison, Sagar V. Parikh, Barbara C. Soyster, Amy L. Tremper, and Jolene R. Bostwick, Consultant. Ambulatory Clinical Guidelines Oversight: R. Van Harrison, April L. Proudlock, and Karl T. Rew.
  Ann Arbor (MI): Michigan Medicine University of Michigan; February 2021.
• Pain Management
  Jill N. Fenske, Co-lead, Daniel W. Berland, Co-lead, SriKrishna Chandran, R. Van Harrison, Jill Schneiderhan, and Paul E. Hilliard. Consultants: Kimberly C. Bialik, Daniel J. Clauw, Desmond A. Lowe, Kathleen S. Mehari, Michael A. Smith, and Susan G. Urba. Ambulatory Clinical Guidelines Oversight: R. Van Harrison, April L. Proudlock, and Karl T. Rew.
  Ann Arbor (MI): Michigan Medicine University of Michigan; January 2021.
• Low Back Pain
  Anthony E. Chiodo, Lead, Suvarna N. Bhat, R. Van Harrison, Gregory D. Shumer, Ronald A. Wasserman, Paul Park, Consultant, and Rakesh D. Patel, Consultant. Ambulatory Clinical Guidelines Oversight: R. Van Harrison, April L. Proudlock, and Karl T. Rew.
  Ann Arbor (MI): Michigan Medicine University of Michigan; November 2020.
• Chronic Obstructive Pulmonary Disease
  Davoren A. Chick, Paul J. Grant, R. Van Harrison, Amal Othman, Sarah E. Roark, MeiLan K. Han, Tami L. Remington, and Noah Leja.
  Ann Arbor (MI): Michigan Medicine University of Michigan; July 2020.
• Management of Indirect Neonatal Hyperbilirubinemia
  Nicole S Sroufe, co-lead, Jennifer L Vredeveld, co-lead, Stephanie L Goodson, Sahoko H Little, Robert E Schumacher, F Jacob Seagull, and Maria S Skoczylas. Consultants: Linda D Gobeski, Debra K Horvath, Pamela K Hurley, Kelly A McCarley, Carolyn M Pawlowski, Deborah R Retzer, Kristin Schuster, Michelle Nemshak, and Rebecca Pehovic.
  Ann Arbor (MI): Michigan Medicine University of Michigan; June 2020.
• Obesity Prevention and Management
  Kelly A Orringer, R Van Harrison, Satyen S Nichani, Margaret A Riley, Amy E Rothberg, Lori E Trudeau, and Yvette White.
  Ann Arbor (MI): Michigan Medicine University of Michigan; June 2020.
• Inpatient Diabetes Guideline for Adult Non-Critically Ill Patients
  Roma Y Gianchandani, Jennifer L Iyengar, Simona O Butler, Mark C Chames, Erica Raymond, Barbra S Miller, Jennifer L Pesenecker, Subramanian Sathishkumar, F Jacob Seagull, and David H Wesorick.
  Ann Arbor (MI): Michigan Medicine University of Michigan; May 22, 2020.
• Alcohol Withdrawal in Hospitalized Patients: Michigan Alcohol Withdrawal Severity (MAWS) Protocol
  Stephanie Czarnik, Mary Jo Kocan, Stephen Strobbe, Cesar Alaniz, Scott Ciarkowski, Nell Kirst, Michael Lukela, Kelly Malloy, Lisa Seyfried, David Somand, Pam Walker, Winnie Wood, and F Jacob Seagull.
  Ann Arbor (MI): Michigan Medicine University of Michigan; January 2020.
• Clostridioides difficile Infection in Adults and Children
  Tejal N Gandhi, Krishna Rao, Meghan A Arnold, (consultant), Gregory Eschenauer, John Y Kao, Lena M Napolitano, F Jacob Seagull, David M Somand, Alison Tribble, Amanda M Valyko, Laraine L Washer, (consultant), and Michael E Watson, Jr.
  Ann Arbor (MI): Michigan Medicine University of Michigan; December 2019.
• Diabetic Foot Infections
  John P. Mills, Payal Patel, Eric Broekhuizen, (consultant), Stephanie Burdick, Christina DeGeorge, Katherine A. Gallagher, Steven C. Haase, (consultant), Crystal M. Holmes, Jon A. Jacobson, Jerod L. Nagel, F. Jacob Seagull, Aaron E. Silver, David M. Somand, Paul G. Talusan, Jeffrey Wensman, (consultant), and James S. Wrobel.
  Ann Arbor (MI): Michigan Medicine University of Michigan; October 2019.
• Special Topics in Venous Thromboembolism
  Paul J Grant, Anthony J Courey, Sarah Hanigan, Mark S Kolbe, Steven L Kronick, Andrea Obi, F Jacob Seagull, Suman L Sood, Thomas W Wakefield, David M Williams, James B Froehlich, Robert Fontana, Jonathan W Haft, and Christopher J Sonnenday.
  Ann Arbor (MI): Michigan Medicine University of Michigan; February 2019.
• Vertebral Osteomyelitis, Discitis, and Spinal Epidural Abscess in Adults
  Carol E. Chenoweth, Benjamin S. Bassin, Megan R. Mack, Mark E. Oppenlander, Rakesh D. Patel, Douglas J. Quint, and F. Jacob Seagull.
  Ann Arbor (MI): Michigan Medicine University of Michigan; December 2018.
• Management of Indirect Neonatal Hyperbilirubinemia
  Nicole S Sroufe, Jennifer L Vredeveld, Michael Levy, Sahoko H Little, Robert E Schumacher, F Jacob Seagull, and Maria S Skoczylas.
  Ann Arbor (MI): Michigan Medicine University of Michigan; October 2017.