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Knowles CH, Booth L, Brown SR, et al. Non-drug therapies for the management of chronic constipation in adults: the CapaCiTY research programme including three RCTs. Southampton (UK): NIHR Journals Library; 2021 Nov. (Programme Grants for Applied Research, No. 9.14.)

Cover of Non-drug therapies for the management of chronic constipation in adults: the CapaCiTY research programme including three RCTs

Non-drug therapies for the management of chronic constipation in adults: the CapaCiTY research programme including three RCTs.

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References

1.
Stewart WF, Liberman JN, Sandler RS, Woods MS, Stemhagen A, Chee E, et al. Epidemiology of constipation (EPOC) study in the United States: relation of clinical subtypes to sociodemographic features. Am J Gastroenterol 1999;94:3530–40. 10.1111/j.1572-0241.1999.01642.x [PubMed: 10606315] [CrossRef]
2.
van den Berg MM, Benninga MA, Di Lorenzo C. Epidemiology of childhood constipation: a systematic review. Am J Gastroenterol 2006;101:2401–9. 10.1111/j.1572-0241.2006.00771.x [PubMed: 17032205] [CrossRef]
3.
Sonnenberg A, Koch TR. Physician visits in the United States for constipation: 1958 to 1986. Dig Dis Sci 1989;34:606–11. 10.1007/BF01536339 [PubMed: 2784759] [CrossRef]
4.
McCrea GL, Miaskowski C, Stotts NA, Macera L, Paul SM, Varma MG. Gender differences in self-reported constipation characteristics, symptoms, and bowel and dietary habits among patients attending a specialty clinic for constipation. Gend Med 2009;6:259–71. 10.1016/j.genm.2009.04.007 [PubMed: 19467522] [CrossRef]
5.
Mugie SM, Benninga MA, Di Lorenzo C. Epidemiology of constipation in children and adults: a systematic review. Best Pract Res Clin Gastroenterol 2011;25:3–18. 10.1016/j.bpg.2010.12.010 [PubMed: 21382575] [CrossRef]
6.
Sonnenberg A, Koch TR. Epidemiology of constipation in the United States. Dis Colon Rectum 1989;32:1–8. 10.1007/BF02554713 [PubMed: 2910654] [CrossRef]
7.
Probert CS, Emmett PM, Heaton KW. Some determinants of whole-gut transit time: a population-based study. QJM 1995;88:311–15. [PubMed: 7796084]
8.
Cook IJ, Talley NJ, Benninga MA, Rao SS, Scott SM. Chronic constipation: overview and challenges. Neurogastroenterol Motil 2009;21(Suppl. 2):1–8. 10.1111/j.1365-2982.2009.01399.x [PubMed: 19824933] [CrossRef]
9.
Knowles CH, Scott SM, Rayner C, Glia A, Lindberg G, Kamm MA, Lunniss PJ. Idiopathic slow-transit constipation: an almost exclusively female disorder. Dis Colon Rectum 2003;46:1716–17. 10.1007/BF02660783 [PubMed: 14668603] [CrossRef]
10.
Wald A, Scarpignato C, Mueller-Lissner S, Kamm MA, Hinkel U, Helfrich I, et al. A multinational survey of prevalence and patterns of laxative use among adults with self-defined constipation. Aliment Pharmacol Ther 2008;28:917–30. 10.1111/j.1365-2036.2008.03806.x [PubMed: 18644012] [CrossRef]
11.
Irvine EJ, Ferrazzi S, Pare P, Thompson WG, Rance L. Health-related quality of life in functional GI disorders: focus on constipation and resource utilization. Am J Gastroenterol 2002;97:1986–93. 10.1111/j.1572-0241.2002.05843.x [PubMed: 12190165] [CrossRef]
12.
Shah ND, Chitkara DK, Locke GR, Meek PD, Talley NJ. Ambulatory care for constipation in the United States, 1993-2004. Am J Gastroenterol 2008;103:1746–53. [PubMed: 18557708]
13.
Poulton B, Thomas S. The nursing cost of constipation. Primary Health Care 1999;9:17–22. 10.7748/phc.9.9.17.s9 [CrossRef]
14.
NHS Business Services Authority. Prescription Cost Analysis: England. URL: https:​//nhsbsa-opendata​.s3.eu-west-2.amazonaws​.com/pca/pca_summary​_tables_2020_21_v001.xlsx (accessed 20 August 2021).
15.
Scott SM, van den Berg MM, Benninga MA. Rectal sensorimotor dysfunction in constipation: best practice and research. Best Pract Res Clin Gastroenterol 2011;25:103–18. 10.1016/j.bpg.2011.01.001 [PubMed: 21382582] [CrossRef]
16.
National Institute for Health and Care Excellence. Constipation in Children and Young People: Diagnosis and Management. Clinical Guideline [ CG99 ]. URL: www​.nice.org.uk/guidance/cg99 (accessed 3 September 2020).
17.
Bardisa-Ezcurra L, Ullman R, Gordon J, Guideline Development Group. Diagnosis and management of idiopathic childhood constipation: summary of NICE guidance. BMJ 2010;340:c2585. 10.1136/bmj.c2585 [PubMed: 20516006] [CrossRef]
18.
Hooban S. NICE’s first guideline on idiopathic childhood constipation aims to standardise practice. Nurs Times 2010;106:14. [PubMed: 21322420]
19.
Camilleri M, Kerstens R, Rykx A, Vandeplassche L. A placebo-controlled trial of prucalopride for severe chronic constipation. N Engl J Med 2008;358:2344–54. 10.1056/NEJMoa0800670 [PubMed: 18509121] [CrossRef]
20.
Lembo AJ, Johanson JF, Parkman HP, Rao SS, Miner PB, Ueno R. Long-term safety and effectiveness of lubiprostone, a chloride channel (ClC-2) activator, in patients with chronic idiopathic constipation. Dig Dis Sci 2011;56:2639–45. 10.1007/s10620-011-1801-0 [PMC free article: PMC3169778] [PubMed: 21769655] [CrossRef]
21.
Lembo AJ, Kurtz CB, Macdougall JE, Lavins BJ, Currie MG, Fitch DA, et al. Efficacy of linaclotide for patients with chronic constipation. Gastroenterology 2010;138:886–95.e1. 10.1053/j.gastro.2009.12.050 [PubMed: 20045700] [CrossRef]
22.
Lembo AJ, Schneier HA, Shiff SJ, Kurtz CB, MacDougall JE, Jia XD, et al. Two randomized trials of linaclotide for chronic constipation. N Engl J Med 2011;365:527–36. 10.1056/NEJMoa1010863 [PubMed: 21830967] [CrossRef]
23.
Kamm MA, Dudding TC, Melenhorst J, Jarrett M, Wang Z, Buntzen S, et al. Sacral nerve stimulation for intractable constipation. Gut 2010;59:333–40. 10.1136/gut.2009.187989 [PubMed: 20207638] [CrossRef]
24.
Maeda Y, Lundby L, Buntzen S, Laurberg S. Sacral nerve stimulation for constipation: suboptimal outcome and adverse events. Dis Colon Rectum 2010;53:995–9. 10.1007/DCR.0b013e3181d64207 [PubMed: 20551750] [CrossRef]
25.
Knowles CH, Dinning PG, Pescatori M, Rintala R, Rosen H. Surgical management of constipation. Neurogastroenterol Motil 2009;21(Suppl. 2):62–71. 10.1111/j.1365-2982.2009.01405.x [PubMed: 19824939] [CrossRef]
26.
Knowles CH, Thin N, Gill K, Bhan C, Grimmer K, Lunniss PJ, et al. Prospective randomized double-blind study of temporary sacral nerve stimulation in patients with rectal evacuatory dysfunction and rectal hyposensitivity. Ann Surg 2012;255:643–9. 10.1097/SLA.0b013e318247d49f [PubMed: 22418005] [CrossRef]
27.
Campbell H, Hotchkiss R, Bradshaw N, Porteous M. Integrated care pathways. BMJ 1998;316:133. 10.1136/bmj.316.7125.133 [PMC free article: PMC2665398] [PubMed: 9462322] [CrossRef]
28.
Vollebregt PF, Burgell RE, Hooper RL, Knowles CH, Scott SM. Clinical impact of rectal hyposensitivity: a cross-sectional study of 2,876 patients with refractory functional constipation. Am J Gastroenterol 2021;116:758–68. 10.14309/ajg.0000000000001039 [PubMed: 33982946] [CrossRef]
29.
Vollebregt PF, Wiklendt L, Dinning PG, Knowles CH, Scott SM. Coexistent faecal incontinence and constipation: a cross-sectional study of 4027 adults undergoing specialist assessment. EClinicalMedicine 2020;27:100572. 10.1016/j.eclinm.2020.100572 [PMC free article: PMC7599308] [PubMed: 33150331] [CrossRef]
30.
American College of Gastroenterology Chronic Constipation Task F. An evidence-based approach to the management of chronic constipation in North America. Am J Gastroenterol 2005;100(Suppl. 1):S1–4. 10.1111/j.1572-0241.2005.50613_1.x [PubMed: 16008640] [CrossRef]
31.
Map of Medicine. Constipation in Adults and the Elderly. URL: http://healthguides​.mapofmedicine​.com/choices​/map/constipation​_in_adults_and_the_elderly1.html (accessed 3 September 2020).
32.
Wade DT, Collin C. The Barthel ADL Index: a standard measure of physical disability? Intl Disabil Stud 1988;10:64–7. 10.3109/09638288809164105 [PubMed: 3042746] [CrossRef]
33.
Palit S, Bhan C, Lunniss PJ, Boyle DJ, Gladman MA, Knowles CH, Scott SM. Evacuation proctography: a reappraisal of normal variability. Colorectal Dis 2014;16:538–46. 10.1111/codi.12595 [PubMed: 24528668] [CrossRef]
34.
Carrington EV, Heinrich H, Knowles CH, Rao SS, Fox M, Scott SM, et al. Methods of anorectal manometry vary widely in clinical practice: results from an international survey. Neurogastroenterol Moti 2017;29:e13016. 10.1111/nmo.13016 [PubMed: 28101937] [CrossRef]
35.
Mahieu P, Pringot J, Bodart P. Defecography: II. Contribution to the diagnosis of defecation disorders. Gastrointest Radiol 1984;9:253–61. 10.1007/BF01887846 [PubMed: 6468863] [CrossRef]
36.
Roberts JP, Womack NR, Hallan RI, Thorpe AC, Williams NS. Evidence from dynamic integrated proctography to redefine anismus. Br J Surg 1992;79:1213–15. 10.1002/bjs.1800791140 [PubMed: 1467908] [CrossRef]
37.
Womack NR, Williams NS, Holmfield JH, Morrison JF, Simpkins KC. New method for the dynamic assessment of anorectal function in constipation. Br J Surg 1985;72:994–8. 10.1002/bjs.1800721221 [PubMed: 4084758] [CrossRef]
38.
Bharucha AE, Dorn SD, Lembo A, Pressman A, American Gastroenterological Association. American Gastroenterological Association medical position statement on constipation. Gastroenterology 2013;144:211–17. 10.1053/j.gastro.2012.10.029 [PubMed: 23261064] [CrossRef]
39.
Rao SS, Mudipalli RS, Stessman M, Zimmerman B. Investigation of the utility of colorectal function tests and Rome II criteria in dyssynergic defecation (Anismus). Neurogastroenterol Motil 2004;16:589–96. 10.1111/j.1365-2982.2004.00526.x [PubMed: 15500515] [CrossRef]
40.
Ratuapli SK, Bharucha AE, Noelting J, Harvey DM, Zinsmeister AR. Phenotypic identification and classification of functional defecatory disorders using high-resolution anorectal manometry. Gastroenterology 2013;144:314–22.e2. 10.1053/j.gastro.2012.10.049 [PMC free article: PMC3681888] [PubMed: 23142135] [CrossRef]
41.
Farthing MJ, Lennard-jones JE. Sensibility of the rectum to distension and the anorectal distension reflex in ulcerative colitis. Gut 1978;19:64–9. 10.1136/gut.19.1.64 [PMC free article: PMC1411776] [PubMed: 304827] [CrossRef]
42.
Jameson JS, Chia YW, Kamm MA, Speakman CT, Chye YH, Henry MM. Effect of age, sex and parity on anorectal function. Br J Surg 1994;81:1689–92. 10.1002/bjs.1800811143 [PubMed: 7827909] [CrossRef]
43.
Zarate N, Knowles CH, Newell M, Garvie NW, Gladman MA, Lunniss PJ, et al. In patients with slow transit constipation, the pattern of colonic transit delay does not differentiate between those with and without impaired rectal evacuation. Am J Gastroenterol 2008;103:427–34. 10.1111/j.1572-0241.2007.01675.x [PubMed: 18070233] [CrossRef]
44.
Preston DM, Lennard-Jones JE. Anismus in chronic constipation. Dig Dis Sci 1985;30:413–18. 10.1007/BF01318172 [PubMed: 3987474] [CrossRef]
45.
Barnes PR, Lennard-Jones JE. Balloon expulsion from the rectum in constipation of different types. Gut 1985;26:1049–52. 10.1136/gut.26.10.1049 [PMC free article: PMC1432954] [PubMed: 4054703] [CrossRef]
46.
Öncü K, Özel AM, Demırtürk L, Gürbüz AK, Yazgan Y, Kizilkaya E. Determination of the frequency of dyssynergic defecation and patient characteristics in patients with functional constipation. Turk J Gastroenterol 2010;21:372–80. 10.4318/tjg.2010.0123 [PubMed: 21331990] [CrossRef]
47.
Hinton JM, Lennard-Jones JE. Constipation: definition and classification. Postgrad Med J 1968;44:720–3. 10.1136/pgmj.44.515.720 [PMC free article: PMC2466679] [PubMed: 5705375] [CrossRef]
48.
Evans RC, Kamm MA, Hinton JM, Lennard-Jones JE. The normal range and a simple diagram for recording whole gut transit time. Int J Colorectal Dis 1992;7:15–17. 10.1007/BF01647654 [PubMed: 1588218] [CrossRef]
49.
Mahieu P, Pringot J, Bodart P. Defecography: I. Description of a new procedure and results in normal patients. Gastrointest Radiol 1984;9:247–51. 10.1007/BF01887845 [PubMed: 6468862] [CrossRef]
50.
Pilkington SA, Nugent KP, Brenner J, Harris S, Clarke A, Lamparelli M, et al. Barium proctography vs magnetic resonance proctography for pelvic floor disorders: a comparative study. Colorectal Dis 2012;14:1224–30. 10.1111/j.1463-1318.2012.02945.x [PubMed: 22251617] [CrossRef]
51.
McColl E. Best practice in symptom assessment: a review. Gut 2004;53(Suppl. 4):iv49–54. 10.1136/gut.2003.034355 [PMC free article: PMC1867779] [PubMed: 15082615] [CrossRef]
52.
Stone AA, Shiffman S, Schwartz JE, Broderick JE, Hufford MR. Patient non-compliance with paper diaries. BMJ 2002;324:1193–4. 10.1136/bmj.324.7347.1193 [PMC free article: PMC111114] [PubMed: 12016186] [CrossRef]
53.
Verbrugge LM. Health diaries. Med Care 1980;18:73–95. 10.1097/00005650-198001000-00006 [PubMed: 6986517] [CrossRef]
54.
Marquis P, De La Loge C, Dubois D, McDermott A, Chassany O. Development and validation of the Patient Assessment of Constipation Quality of Life questionnaire. Scand J Gastroenterol 2005;40:540–51. 10.1080/00365520510012208 [PubMed: 16036506] [CrossRef]
55.
Cowlam S, Milburn S, McColl E, Yiannakou Y. Preliminary validation of the PAC-QOL questionnaire for chronic idiopathic constipation in patients in the UK. Gastroenterology 2007;132:A442.
56.
Yiannakou Y, Etherson K, Close H, Kasim A, Mercer-Jones M, Plusa S, et al. A randomized double-blinded sham-controlled cross-over trial of tined-lead sacral nerve stimulation testing for chronic constipation. Eur J Gastroenterol Hepatol 2019;31:653–60. 10.1097/MEG.0000000000001379 [PubMed: 31009400] [CrossRef]
57.
Dubois D, Gilet H, Viala-Danten M, Tack J. Psychometric performance and clinical meaningfulness of the Patient Assessment of Constipation-Quality of Life questionnaire in prucalopride (RESOLOR) trials for chronic constipation. Neurogastroenterol Motil 2010;22:e54–63. 10.1111/j.1365-2982.2009.01408.x [PubMed: 19761492] [CrossRef]
58.
Paterson C. Measuring outcomes in primary care: a patient generated measure, MYMOP, compared with the SF-36 health survey. BMJ 1996;312:1016–20. 10.1136/bmj.312.7037.1016 [PMC free article: PMC2350813] [PubMed: 8616351] [CrossRef]
59.
Curtis L. Unit Costs of Health and Social Care 2006. Canterbury: PSSRU, University of Kent; 2006.
60.
Kroenke K, Spitzer RL. The PHQ-9: a new depression diagnostic and severity measure. Psychiat Ann 2002;32:509–15. 10.3928/0048-5713-20020901-06 [CrossRef]
61.
Spitzer RL, Kroenke K, Williams JB, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med 2006;166:1092–7. 10.1001/archinte.166.10.1092 [PubMed: 16717171] [CrossRef]
62.
Spence M, Moss-Morris R, Chalder T. The Behavioural Responses to Illness Questionnaire (BRIQ): a new predictive measure of medically unexplained symptoms following acute infection. Psychol Med 2005;35:583–93. 10.1017/s0033291704003484 [PubMed: 15856728] [CrossRef]
63.
Broadbent E, Petrie KJ, Main J, Weinman J. The brief illness perception questionnaire. J Psychosom Res 2006;60:631–7. 10.1016/j.jpsychores.2005.10.020 [PubMed: 16731240] [CrossRef]
64.
NHS Digital. Prescription Cost Analysis – England, 2018. URL: https://digital​.nhs.uk​/data-and-information​/publications/statistical​/prescription-cost-analysis/2018 (accessed 24 August 2021).
65.
Office for National Statistics (ONS). Average Weekly Earnings in Great Britain: February 2020. London: ONS; 2020.
66.
Curtis L, Burns A. Unit Costs of Health and Social Care 2018. Canterbury: PSSRU, University of Kent; 2018.
67.
Curtis L, Burns A. Unit Costs of Health and Social Care 2015. Canterbury: PSSRU, University of Kent; 2015.
68.
NHS England. NHS Community Pharmacist Consultation Service: Toolkit for Pharmacy Staff. 2019. URL: www​.england.nhs.uk/publication​/nhs-community-pharmacist-consultation-service-toolkit-for-pharmacy-staff (accessed 3 July 2020).
69.
NHS England. 2018/19 National Cost Collection Publication. URL: www​.england.nhs.uk/publication​/2018-19-national-cost-collection-data-publication (accessed 3 July 2020).
70.
NHS Digital. Prescription Cost Analysis – England, 2018 [PAS]. URL: https://digital​.nhs.uk​/data-and-information​/publications/statistical​/prescription-cost-analysis/2018 (accessed 3 June 2019).
71.
van Hout B, Janssen MF, Feng YS, Kohlmann T, Busschbach J, Golicki D, et al. Interim scoring for the EQ-5D-5L: mapping the EQ-5D-5L to EQ-5D-3L value sets. Val Health 2012;15:708–15. 10.1016/j.jval.2012.02.008 [PubMed: 22867780] [CrossRef]
72.
National Institute for Health and Care Excellence. Guide to the Methods of Technology Appraisal 2013. URL: www​.nice.org.uk/process​/pmg9/resources/guide-to-the-methods-of-technology-appraisal-2013-pdf-2007975843781 (accessed 3 July 2020). [PubMed: 27905712]
73.
Sterne JA, White IR, Carlin JB, Spratt M, Royston P, Kenward MG, et al. Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls. BMJ 2009;338:b2393. 10.1136/bmj.b2393 [PMC free article: PMC2714692] [PubMed: 19564179] [CrossRef]
74.
Faria R, Gomes M, Epstein D, White IR. A guide to handling missing data in cost-effectiveness analysis conducted within randomised controlled trials. PharmacoEconomics 2014;32:1157–70. 10.1007/s40273-014-0193-3 [PMC free article: PMC4244574] [PubMed: 25069632] [CrossRef]
75.
White IR, Royston P, Wood AM. Multiple imputation using chained equations: issues and guidance for practice. Stat Med 2011;30:377–99. 10.1002/sim.4067 [PubMed: 21225900] [CrossRef]
76.
Claxton K, Sculpher M, Palmer S, Culyer AJ. Causes for concern: is NICE failing to uphold its responsibilities to all NHS patients? Health Econ 2015;24:1–7. 10.1002/hec.3130 [PubMed: 25488707] [CrossRef]
77.
Claxton K, Martin S, Soares M, Rice N, Spackman E, Hinde S, et al. Methods for the estimation of the National Institute for Health and Care Excellence cost-effectiveness threshold. Health Technol Assess 2015;19(14). 10.3310/hta19140 [PMC free article: PMC4781395] [PubMed: 25692211] [CrossRef]
78.
Fenwick E, Claxton K, Sculpher M. Representing uncertainty: the role of cost-effectiveness acceptability curves. Health Econ 2001;10:779–87. 10.1002/hec.635 [PubMed: 11747057] [CrossRef]
79.
Willan AR, Briggs AH, Hoch JS. Regression methods for covariate adjustment and subgroup analysis for non-censored cost-effectiveness data. Health Econ 2004;13:461–75. 10.1002/hec.843 [PubMed: 15127426] [CrossRef]
80.
Claxton K, Sculpher M, Drummond M. A rational framework for decision making by the National Institute For Clinical Excellence (NICE). Lancet 2002;360:711–15. 10.1016/S0140-6736(02)09832-X [PubMed: 12241891] [CrossRef]
81.
Husereau D, Drummond M, Petrou S, Carswell C, Moher D, Greenberg D, et al. Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement. Eur J Health Econ 2013;14:367–72. 10.1007/s10198-013-0471-6 [PubMed: 23526140] [CrossRef]
82.
Fereday J, Muir-Cochrane E. Demonstrating rigor using thematic analysis: a hybrid approach of inductive and deductive coding and theme development. Int J Qual Meth 2006;5. 10.1177/160940690600500107 [CrossRef]
83.
Riley E. NHS surgeon is sacked for performing controversial bowel mesh operations that left dozens of patients in severe pain. Daily Mail, 26 June 2019.
84.
Gold SM, Köhler-Forsberg O, Moss-Morris R, Mehnert A, Miranda JJ, Bullinger M, et al. Comorbid depression in medical diseases. Nat Rev Dis Primers 2020;6:69. 10.1038/s41572-020-0200-2 [PubMed: 32820163] [CrossRef]
85.
Chiotakakou-Faliakou E, Kamm MA, Roy AJ, Storrie JB, Turner IC. Biofeedback provides long-term benefit for patients with intractable, slow and normal transit constipation. Gut 1998;42:517–21. 10.1136/gut.42.4.517 [PMC free article: PMC1727071] [PubMed: 9616314] [CrossRef]
86.
Bleijenberg G, Kuijpers HC. Biofeedback treatment of constipation: a comparison of two methods. Am J Gastroenterol 1994;89:1021–6. [PubMed: 8017359]
87.
Koutsomanis D, Lennard-Jones JE, Roy AJ, Kamm MA. Controlled randomised trial of visual biofeedback versus muscle training without a visual display for intractable constipation. Gut 1995;37:95–9. 10.1136/gut.37.1.95 [PMC free article: PMC1382776] [PubMed: 7672690] [CrossRef]
88.
Heymen S, Scarlett Y, Jones K, Ringel Y, Drossman D, Whitehead WE. Randomized, controlled trial shows biofeedback to be superior to alternative treatments for patients with pelvic floor dyssynergia-type constipation. Dis Colon Rectum 2007;50:428–41. 10.1007/s10350-006-0814-9 [PubMed: 17294322] [CrossRef]
89.
Heymen S, Wexner SD, Vickers D, Nogueras JJ, Weiss EG, Pikarsky AJ. Prospective, randomized trial comparing four biofeedback techniques for patients with constipation. Dis Colon Rectum 1999;42:1388–93. 10.1007/BF02235034 [PubMed: 10566525] [CrossRef]
90.
Glia A, Gylin M, Gullberg K, Lindberg G. Biofeedback retraining in patients with functional constipation and paradoxical puborectalis contraction: comparison of anal manometry and sphincter electromyography for feedback. Dis Colon Rectum 1997;40:889–95. 10.1007/BF02051194 [PubMed: 9269803] [CrossRef]
91.
Chiarioni G, Whitehead WE, Pezza V, Morelli A, Bassotti G. Biofeedback is superior to laxatives for normal transit constipation due to pelvic floor dyssynergia. Gastroenterology 2006;130:657–64. 10.1053/j.gastro.2005.11.014 [PubMed: 16530506] [CrossRef]
92.
Rao SS. Biofeedback therapy for constipation in adults. Best Pract Res Clin Gastroenterology 2011;25:159–66. 10.1016/j.bpg.2011.01.004 [PMC free article: PMC3073852] [PubMed: 21382587] [CrossRef]
93.
Bharucha AE, Pemberton JH, Locke GR. American Gastroenterological Association technical review on constipation. Gastroenterology 2013;144:218–38. 10.1053/j.gastro.2012.10.028 [PMC free article: PMC3531555] [PubMed: 23261065] [CrossRef]
94.
Enck P, Van der Voort IR, Klosterhalfen S. Biofeedback therapy in fecal incontinence and constipation. Neurogastroenterol Motil 2009;21:1133–41. 10.1111/j.1365-2982.2009.01345.x [PubMed: 19566591] [CrossRef]
95.
Etherson KJ, Horrocks EJ, Scott SM, Knowles CH, Yiannakou Y. A national biofeedback practitioners service evaluation: focus on chronic idiopathic constipation. Frontline Gastroenterol 2017;8:62–7. 10.1136/flgastro-2015-100660 [PMC free article: PMC5369454] [PubMed: 28839886] [CrossRef]
96.
Rao SS, Seaton K, Miller M, Brown K, Nygaard I, Stumbo P, et al. Randomized controlled trial of biofeedback, sham feedback, and standard therapy for dyssynergic defecation. Clin Gastroenterol Hepatol 2007;5:331–8. 10.1016/j.cgh.2006.12.023 [PubMed: 17368232] [CrossRef]
97.
Chiarioni G, Salandini L, Whitehead WE. Biofeedback benefits only patients with outlet dysfunction, not patients with isolated slow transit constipation. Gastroenterology 2005;129:86–97. 10.1053/j.gastro.2005.05.015 [PubMed: 16012938] [CrossRef]
98.
Simón MA, Bueno AM. Behavioural treatment of the dyssynergic defecation in chronically constipated elderly patients: a randomized controlled trial. Appl Psychophysiol Biofeedback 2009;34:273–7. 10.1007/s10484-009-9100-7 [PubMed: 19618262] [CrossRef]
99.
Grossi U, Carrington EV, Bharucha AE, Horrocks EJ, Scott SM, Knowles CH. Diagnostic accuracy study of anorectal manometry for diagnosis of dyssynergic defecation. Gut 2016;65:447–55. 10.1136/gutjnl-2014-308835 [PMC free article: PMC4686376] [PubMed: 25765461] [CrossRef]
100.
Farid M, El Monem HA, Omar W, El Nakeeb A, Fikry A, Youssef T, et al. Comparative study between biofeedback retraining and botulinum neurotoxin in the treatment of anismus patients. Int J Colorectal Dis 2009;24:115–20. 10.1007/s00384-008-0567-0 [PubMed: 18719924] [CrossRef]
101.
Lehur PA, Stuto A, Fantoli M, Villani RD, Queralto M, Lazorthes F, et al. Outcomes of stapled transanal rectal resection vs. biofeedback for the treatment of outlet obstruction associated with rectal intussusception and rectocele: a multicenter, randomized, controlled trial. Dis Colon Rectum 2008;51:1611–18. 10.1007/s10350-008-9378-1 [PubMed: 18642046] [CrossRef]
102.
Woodward S, Norton C, Chiarelli P. Biofeedback for treatment of chronic idiopathic constipation in adults. Cochrane Database Syst Rev 2014;3:. 10.1002/14651858.CD008486.pub2 CD008486 [PMC free article: PMC10618629] [PubMed: 24668156] [CrossRef]
103.
Rome Foundation. Rome IV Criteria. URL: https:​//theromefoundation​.org/rome-iv/rome-iv-criteria/ (accessed 24 August 2021).
104.
Kamm MA. Clinical case: chronic constipation. Gastroenterology 2006;131:233–9. 10.1053/j.gastro.2006.05.027 [PubMed: 16831605] [CrossRef]
105.
Rao SS, Ozturk R, Laine L. Clinical utility of diagnostic tests for constipation in adults: a systematic review. Am J Gastroenterol 2005;100:1605–15. 10.1111/j.1572-0241.2005.41845.x [PubMed: 15984989] [CrossRef]
106.
Rao SS. Constipation: evaluation and treatment of colonic and anorectal motility disorders. Gastroenterol Clin North Am 2007;36:687–711, x. 10.1016/j.gtc.2007.07.013 [PubMed: 17950444] [CrossRef]
107.
Locke GR, Pemberton JH, Phillips SF. American Gastroenterological Association Medical Position Statement: guidelines on constipation. Gastroenterology 2000;119:1761–6. 10.1053/gast.2000.20390 [PubMed: 11113098] [CrossRef]
108.
Everitt HA, Landau S, O’Reilly G, Sibelli A, Hughes S, Windgassen S, et al. Assessing telephone-delivered cognitive-behavioural therapy (CBT) and web-delivered CBT versus treatment as usual in irritable bowel syndrome (ACTIB): a multicentre randomised trial. Gut 2019;68:1613–23. 10.1136/gutjnl-2018-317805 [PMC free article: PMC6709776] [PubMed: 30971419] [CrossRef]
109.
Everitt HA, Landau S, O’Reilly G, Sibelli A, Hughes S, Windgassen S, et al. Cognitive behavioural therapy for irritable bowel syndrome: 24-month follow-up of participants in the ACTIB randomised trial. Lancet Gastroenterol Hepatol 2019;4:863–72. 10.1016/S2468-1253(19)30243-2 [PMC free article: PMC7026694] [PubMed: 31492643] [CrossRef]
110.
Carrington EV, Grossi U, Knowles CH, Scott SM. Normal values for high-resolution anorectal manometry: a time for consensus and collaboration. Neurogastroenterol Motil 2014;26:1356–7. 10.1111/nmo.12364 [PubMed: 25167954] [CrossRef]
111.
Carrington EV, Heinrich H, Knowles CH, Fox M, Rao S, Altomare DF, et al. The international anorectal physiology working group (IAPWG) recommendations: standardized testing protocol and the London classification for disorders of anorectal function. Neurogastroenterol Motil 2020;32:e13679. 10.1111/nmo.13679 [PMC free article: PMC6923590] [PubMed: 31407463] [CrossRef]
112.
Christensen P, Krogh K, Buntzen S, Payandeh F, Laurberg S. Long-term outcome and safety of transanal irrigation for constipation and fecal incontinence. Dis Colon Rectum 2009;52:286–92. 10.1007/DCR.0b013e3181979341 [PubMed: 19279425] [CrossRef]
113.
Ausili E, Focarelli B, Tabacco F, Murolo D, Sigismondi M, Gasbarrini A, Rendeli C. Transanal irrigation in myelomeningocele children: an alternative, safe and valid approach for neurogenic constipation. Spinal Cord 2010;48:560–5. 10.1038/sc.2009.186 [PubMed: 20084075] [CrossRef]
114.
Krogh K, Kvitzau B, Jørgensen TM, Laurberg S. [Treatment of anal incontinence and constipation with transanal irrigation.] Ugeskr Laeger 1999;161:253–6. [PubMed: 10025223]
115.
Preziosi G, Gosling J, Raeburn A, Storrie J, Panicker J, Emmanuel A. Transanal irrigation for bowel symptoms in patients with multiple sclerosis. Dis Colon Rectum 2012;55:1066–73. 10.1097/DCR.0b013e3182653bd1 [PubMed: 22965406] [CrossRef]
116.
Emmanuel A. Review of the efficacy and safety of transanal irrigation for neurogenic bowel dysfunction. Spinal Cord 2010;48:664–73. 10.1038/sc.2010.5 [PubMed: 20142830] [CrossRef]
117.
Etherson KJ, Minty I, Bain IM, Cundall J, Yiannakou Y. Transanal irrigation for refractory chronic idiopathic constipation: patients perceive a safe and effective therapy. Gastroenterol Res Pract 2017;2017:3826087. 10.1155/2017/3826087 [PMC free article: PMC5237460] [PubMed: 28115930] [CrossRef]
118.
Morden JP, Lambert PC, Latimer N, Abrams KR, Wailoo AJ. Assessing methods for dealing with treatment switching in randomised controlled trials: a simulation study. BMC Med Res Methodol 2011;11:4. 10.1186/1471-2288-11-4 [PMC free article: PMC3024998] [PubMed: 21223539] [CrossRef]
119.
Knowles CH, Scott M, Lunniss PJ. Outcome of colectomy for slow transit constipation. Ann Surg 1999;230:627–38. 10.1097/00000658-199911000-00004 [PMC free article: PMC1420916] [PubMed: 10561086] [CrossRef]
120.
Lindsey I, Knowles C. Abdominal surgery for chronic constipation. Colorectal Dis 2011;13:1325. 10.1111/j.1463-1318.2011.02836.x [PubMed: 22059861] [CrossRef]
121.
D’Hoore A, Cadoni R, Penninckx F. Long-term outcome of laparoscopic ventral rectopexy for total rectal prolapse. Br J Surg 2004;91:1500–5. 10.1002/bjs.4779 [PubMed: 15499644] [CrossRef]
122.
Boons P, Collinson R, Cunningham C, Lindsey I. Laparoscopic ventral rectopexy for external rectal prolapse improves constipation and avoids de novo constipation. Colorectal Dis 2010;12:526–32. 10.1111/j.1463-1318.2009.01859.x [PubMed: 19486104] [CrossRef]
123.
Wijffels N, Cunningham C, Dixon A, Greenslade G, Lindsey I. Laparoscopic ventral rectopexy for external rectal prolapse is safe and effective in the elderly. Does this make perineal procedures obsolete? Colorectal Dis 2011;13:561–6. 10.1111/j.1463-1318.2010.02242.x [PubMed: 20184638] [CrossRef]
124.
Badrek-Amoudi AH, Roe T, Mabey K, Carter H, Mills A, Dixon AR. Laparoscopic ventral mesh rectopexy in the management of solitary rectal ulcer syndrome: a cause for optimism? Colorectal Dis 2013;15:575–81. 10.1111/codi.12077 [PubMed: 23107777] [CrossRef]
125.
Formijne Jonkers HA, Poierrié N, Draaisma WA, Broeders IA, Consten EC. Laparoscopic ventral rectopexy for rectal prolapse and symptomatic rectocele: an analysis of 245 consecutive patients. Colorectal Dis 2013;15:695–9. 10.1111/codi.12113 [PubMed: 23406289] [CrossRef]
126.
Owais AE, Sumrien H, Mabey K, McCarthy K, Greenslade GL, Dixon AR. Laparoscopic ventral mesh rectopexy in male patients with internal or external rectal prolapse. Colorectal Dis 2014;16:995–1000. 10.1111/codi.12763 [PubMed: 25175930] [CrossRef]
127.
Portier G, Kirzin S, Cabarrot P, Queralto M, Lazorthes F. The effect of abdominal ventral rectopexy on faecal incontinence and constipation in patients with internal intra-anal rectal intussusception. Colorectal Dis 2011;13:914–17. 10.1111/j.1463-1318.2010.02327.x [PubMed: 20497199] [CrossRef]
128.
Slawik S, Soulsby R, Carter H, Payne H, Dixon AR. Laparoscopic ventral rectopexy, posterior colporrhaphy and vaginal sacrocolpopexy for the treatment of recto-genital prolapse and mechanical outlet obstruction. Colorectal Dis 2008;10:138–43. [PubMed: 17498206]
129.
Wong M, Meurette G, Abet E, Podevin J, Lehur PA. Safety and efficacy of laparoscopic ventral mesh rectopexy for complex rectocele. Colorectal Dis 2011;13:1019–23. 10.1111/j.1463-1318.2010.02349.x [PubMed: 20553314] [CrossRef]
130.
Collinson R, Wijffels N, Cunningham C, Lindsey I. Laparoscopic ventral rectopexy for internal rectal prolapse: short-term functional results. Colorectal Dis 2010;12:97–104. 10.1111/j.1463-1318.2009.02049.x [PubMed: 19788493] [CrossRef]
131.
Gosselink MP, Adusumilli S, Harmston C, Wijffels NA, Jones OM, Cunningham C, Lindsey I. Impact of slow transit constipation on the outcome of laparoscopic ventral rectopexy for obstructed defaecation associated with high grade internal rectal prolapse. Colorectal Dis 2013;15:e749–56. 10.1111/codi.12443 [PubMed: 24125518] [CrossRef]
132.
Hidaka J, Elfeki H, Duelund-Jakobsen J, Laurberg S, Lundby L. Functional outcome after laparoscopic posterior sutured rectopexy versus ventral mesh rectopexy for rectal rolapse: six-year follow-up of a double-blind, randomized single-center study. EClinicalMedicine 2019;16:18–22. 10.1016/j.eclinm.2019.08.014 [PMC free article: PMC6890942] [PubMed: 31832616] [CrossRef]
133.
El-Dhuwaib Y, Pandyan A, Knowles CH. Epidemiological trends in surgery for rectal prolapse in England 2001–2012: an adult hospital population-based study. Colorectal Dis 2020;22:1359–66. 10.1111/codi.15094 [PubMed: 32346972] [CrossRef]
134.
Mercer-Jones MA, Brown SR, Knowles CH, Williams AB. Position Statement by The Pelvic Floor Society on behalf of The Association of Coloproctology of Great Britain and Ireland on the use of mesh in ventral mesh rectopexy (VMR). Colorectal Dis 2020;22:1429–35. 10.1111/codi.13893 [PMC free article: PMC7702115] [PubMed: 28926174] [CrossRef]
135.
Knowles CH, Grossi U, Horrocks EJ, Pares D, Vollebregt PF, Chapman M, et al. Surgery for constipation: systematic review and clinical guidance. Paper 1: Introduction & Methods. Colorectal Dis 2017;19(Suppl. 3):5–16. 10.1111/codi.13774 [PubMed: 28960925] [CrossRef]
136.
Grossi U, Horrocks EJ, Mason J, Knowles CH, Williams AB, NIHR CapaCiTY working group. Surgery for constipation: systematic review and practice recommendations. Results IV: recto-vaginal reinforcement procedures. Colorectal Dis 2017;19(Suppl. 3):73–91. 10.1111/codi.13781 [PubMed: 28960924] [CrossRef]
137.
Mercer-Jones M, Grossi U, Pares D, Vollebregt PF, Mason J, Knowles CH, NIHR CapaCiTY working group. Surgery for constipation: systematic review and practice recommendations. Results III: rectal wall excisional procedures (Rectal Excision). Colorectal Dis 2017;19(Suppl. 3):49–72. 10.1111/codi.13772 [PubMed: 28960928] [CrossRef]
138.
Knowles CH, Grossi U, Chapman M, Mason J, NIHR CapaCiTY working group, Pelvic Floor Society. Surgery for constipation: systematic review and practice recommendations. Results I: colonic resection. Colorectal Dis 2017;19(Suppl. 3):17–36. 10.1111/codi.13779 [PubMed: 28960923] [CrossRef]
139.
Pilkington SA, Emmett C, Knowles CH, Mason J, Yiannakou Y, NIHR CapaCiTY working group. Surgery for constipation: systematic review and practice recommendations. Results V: sacral nerve stimulation. Colorectal Dis 2017;19(Suppl. 3):92–100. 10.1111/codi.13780 [PubMed: 28960926] [CrossRef]
140.
Grossi U, Knowles CH, Mason J, Lacy-Colson J, Brown SR, NIHR CapaCiTY working group. Surgery for constipation: systematic review and practice recommendations. Results II: hitching procedures for the rectum (rectal suspension). Colorectal Dis 2017;19(Suppl. 3):37–48. 10.1111/codi.13773 [PubMed: 28960927] [CrossRef]
141.
Knowles CH, Grossi U, Horrocks EJ, Pares D, Vollebregt PF, Chapman M, et al. Surgery for constipation: systematic review and practice recommendations – graded practice and future research recommendations. Colorectal Dis 2017;19(Suppl. 3):101–13. 10.1111/codi.13775 [PubMed: 28960922] [CrossRef]
142.
Independent Medicines and Medical Devices Safety Review. First Do No Harm: The Report of the Independent Medicines and Medical Devices Safety Review. Edinburgh: APS Group; 2020.
143.
Baron GR Briggs AH, Fenwick EAL. Optimal cost-effectiveness decisions: the role of the cost-effectiveness acceptability curve (CEAC), the cost-effectiveness acceptability frontier (CEAF), and the expected value of perfection information (EVPI). Value Health 2008;11:886–97. 10.1111/j.1524-4733.2008.00358.x [PubMed: 18489513] [CrossRef]
144.
D’Hoore A, Penninckx F. Laparoscopic ventral recto(colpo)pexy for rectal prolapse: surgical technique and outcome for 109 patients. Surg Endosc 2006;20:1919–23. 10.1007/s00464-005-0485-y [PubMed: 17031741] [CrossRef]
145.
Haskell H. Cumberlege review exposes stubborn and dangerous flaws in healthcare. BMJ 2020;370:m3099. 10.1136/bmj.m3099 [PubMed: 32763955] [CrossRef]
146.
Joint Formulary Committee. British National Formulary (online). London: BMJ Group and Pharmaceutical Press. URL: www​.medicinescomplete.com (accessed 1 August 2021).
Copyright © 2021 Knowles et al. This work was produced by Knowles et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This is an Open Access publication distributed under the terms of the Creative Commons Attribution CC BY 4.0 licence, which permits unrestricted use, distribution, reproduction and adaption in any medium and for any purpose provided that it is properly attributed. See: https://creativecommons.org/licenses/by/4.0/. For attribution the title, original author(s), the publication source – NIHR Journals Library, and the DOI of the publication must be cited.
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