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Clark AL, Johnson M, Fairhurst C, et al. Does home oxygen therapy (HOT) in addition to standard care reduce disease severity and improve symptoms in people with chronic heart failure? A randomised trial of home oxygen therapy for patients with chronic heart failure. Southampton (UK): NIHR Journals Library; 2015 Sep. (Health Technology Assessment, No. 19.75.)

Cover of Does home oxygen therapy (HOT) in addition to standard care reduce disease severity and improve symptoms in people with chronic heart failure? A randomised trial of home oxygen therapy for patients with chronic heart failure

Does home oxygen therapy (HOT) in addition to standard care reduce disease severity and improve symptoms in people with chronic heart failure? A randomised trial of home oxygen therapy for patients with chronic heart failure.

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List of abbreviations

6MWT

6-minute walk test

AHI

apnoea–hypopnoea index

AMD

adjusted mean difference

ANCOVA

analysis of covariance

BMT

best medical therapy

CCI

Charlson Comorbidity Index

CHF

chronic heart failure

CI

confidence interval

CONSORT

Consolidated Standards of Reporting Trials

COPD

chronic obstructive pulmonary disease

DAOH

days alive and out of hospital

df

degree of freedom

ECG

electrocardiography

EQ-5D

European Quality of Life-5 Dimensions

EQ-5D-3L

European Quality of Life-5 Dimensions-3 Levels

ESS

Epworth Sleepiness Scale

FEV1

forced expiratory volume in 1 second

FVC

forced vital capacity

HADS

Hospital Anxiety and Depression Scale

HOT

home oxygen therapy

HR

hazard ratio

HRQoL

health-related quality of life

HTA

Health Technology Assessment

KPS

Karnofsky Performance Status scale

LTOT

long-term oxygen therapy

LV

left ventricular

LVEF

left ventricular ejection fraction

MLwHF

Minnesota Living with Heart Failure

MRC

Medical Research Council

MREC

Medical Research and Ethics Committee

NEON

North East Oxygen Network

NOT

nocturnal oxygen therapy

NRS

Numerical Rating Scale

NT-proBNP

N-terminal pro-B-type natriuretic hormone

NYHA

New York Heart Association

PaO2

partial pressure of arterial oxygen

QoL

quality of life

RCT

randomised controlled trial

SAE

serious adverse event

SD

standard deviation

SDB

sleep-disordered breathing

SE

standard error

SVR

systemic vascular resistance

Copyright © Queen’s Printer and Controller of HMSO 2015. This work was produced by Clark et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

Included under terms of UK Non-commercial Government License.

Bookshelf ID: NBK316466

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