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Picot J, Cooper K, Bryant J, et al. The Clinical Effectiveness and Cost-Effectiveness of Bortezomib and Thalidomide in Combination Regimens with an Alkylating Agent and a Corticosteroid for the First-Line Treatment of Multiple Myeloma: A Systematic Review and Economic Evaluation. Southampton (UK): NIHR Journals Library; 2011 Dec. (Health Technology Assessment, No. 15.41.)
The Clinical Effectiveness and Cost-Effectiveness of Bortezomib and Thalidomide in Combination Regimens with an Alkylating Agent and a Corticosteroid for the First-Line Treatment of Multiple Myeloma: A Systematic Review and Economic Evaluation.
Show detailsWe would like to thank members of our advisory group who provided expert advice and comments on the protocol and a draft of this report: Professor Graham Jackson, Honorary Clinical Professor of Clinical Haematology Northern Institute for Cancer Research, Newcastle University (Professor Jackson was a Chief Investigator on the MMIX Trial); Dr Alastair Smith, Consultant Haematologist, Southampton General Hospital (Dr Smith has received honoraria from Ortho-Biotech and Celgene during the past 2 years for invited lectures, was a local investigator in the MMIX Trial, undertakes unpaid patient and carer education, and reviews research grant applications for Myeloma UK); Mrs Joan Smith, Secretary, North Manchester & Bury Myeloma Support Group; and Paul Tappenden, Senior Research Fellow, Health Economics and Decision Science, School of Health and Related Research (ScHARR), University of Sheffield.
We would also like to thank the MMIX Trial team for providing unpublished data for this report, in particular: Professor Anthony Child, Professor Gareth Morgan, Dr Sue Bell, Dr Walter Gregory, Mrs Kim Cocks and Mr Alex Szubert.
We are also grateful to Susan Baliss, Finance Manager – Costing, Southampton University Hospitals NHS Trust; Karen Welch, Information Scientist, SHTAC, University of Southampton, for generating and running the literature searches; and Jonathan Shepherd, Principal Research Fellow, SHTAC, for reviewing a draft of this report.
Contributions of authors
J Picot (Research Fellow) developed the research protocol, drafted the background section, assisted in the development of the search strategy, assessed studies for inclusion, extracted data from and quality assessed included studies, synthesised evidence, drafted and edited the final report, and project managed the study.
K Cooper (Senior Research Fellow) developed the research protocol, assessed studies for inclusion, extracted data from, and quality assessed, included studies, synthesised evidence, developed the economic evaluation and drafted the report.
J Bryant (Principal Research Fellow) developed the research protocol, assisted in the development of the search strategy, assessed studies for inclusion, extracted data from and quality assessed included studies, synthesised evidence and drafted the report.
AJ Clegg (Professor) developed the research protocol, assessed studies for inclusion, extracted data from, and quality assessed, included studies, synthesised evidence and drafted the report.
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