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Clinical Review Report: Crisaborole Ointment, 2% (Eucrisa): (Pfizer Canada Inc.): Indication: For topical treatment of mild to moderate atopic dermatitis in patients 2 years of age and older [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Apr.

Cover of Clinical Review Report: Crisaborole Ointment, 2% (Eucrisa)

Clinical Review Report: Crisaborole Ointment, 2% (Eucrisa): (Pfizer Canada Inc.): Indication: For topical treatment of mild to moderate atopic dermatitis in patients 2 years of age and older [Internet].

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Abbreviations

AD

atopic dermatitis

AE

adverse event

CDLQI

Children’s Dermatology Life Quality Index

CI

confidence interval

CrI

credible interval

CSPA

Canadian Skin Patient Alliance

DFI

Dermatitis Family Impact questionnaire

DLQI

Dermatology Life Quality Index

ESC

Eczema Society of Canada

GQ

Global Question

GRCQ

Global Rating of Change Questionnaire

HRQoL

health-related quality of life

IDC

indirect treatment comparison

ISGA

Investigator’s Static Global Assessment

ITT

intention-to-treat population

MCMC

Markov Chain Monte Carlo

MCID

minimal clinically important difference

NMA

network meta-analysis

PDE4

phosphodiesterase type 4

QoL

quality of life

RCT

randomized controlled trial

SAE

serious adverse event

SD

standard deviation

SOC

standard of care

TCI

topical calcineurin inhibitor

TCS

topical corticosteroids

WDAE

withdrawal due to adverse event

Copyright © 2019 Canadian Agency for Drugs and Technologies in Health.

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Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

Bookshelf ID: NBK542347

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