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OnabotulinumtoxinA for Injection (Botox): For the Treatment of Overactive Bladder [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Jul.

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OnabotulinumtoxinA for Injection (Botox): For the Treatment of Overactive Bladder [Internet].

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Clinical Review Report

DrugonabotulinumtoxinA for injection (Botox)
IndicationFor the treatment of overactive bladder with symptoms of urinary incontinence, urgency, and frequency, in adult patients who have an inadequate response to or are intolerant of anticholinergic medication.
Listing requestFor the treatment of refractory urinary incontinence due to overactive bladder.
ManufacturerAllergan, Inc.

ABBREVIATIONS

EXECUTIVE SUMMARY

1. INTRODUCTION

2. OBJECTIVES AND METHODS

3. RESULTS

4. DISCUSSION

5. CONCLUSIONS

APPENDIX 1 PATIENT INPUT SUMMARY

APPENDIX 2 LITERATURE SEARCH STRATEGY

APPENDIX 3 EXCLUDED STUDIES

APPENDIX 4 DETAILED OUTCOME DATA

APPENDIX 5 VALIDITY OF OUTCOME MEASURES

APPENDIX 6 SUMMARY OF OPEN-LABEL EXTENSION STUDY

REFERENCES

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Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

Bookshelf ID: NBK349317

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