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Riociguat (Adempas): Management of Inoperable Chronic Thromboembolic Pulmonary Hypertension [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Jul.

Cover of Riociguat (Adempas)

Riociguat (Adempas): Management of Inoperable Chronic Thromboembolic Pulmonary Hypertension [Internet].

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Clinical Review Report

Drugriociguat (Adempas)
IndicationManagement of inoperable chronic thromboembolic pulmonary hypertension (CTEPH, WHO Group 4) or persistent or recurrent CTEPH after surgical treatment in adult patients ≥ 18 years of age with WHO functional class II or III pulmonary hypertension.
Listing requestAs per indication
ManufacturerBayer HealthCare

ABBREVIATIONS

EXECUTIVE SUMMARY

1. INTRODUCTION

2. OBJECTIVES AND METHODS

3. RESULTS

4. DISCUSSION

5. CONCLUSIONS

APPENDIX 1 PATIENT INPUT SUMMARY

APPENDIX 2 LITERATURE SEARCH STRATEGY

APPENDIX 3 EXCLUDED STUDIES

APPENDIX 4 DETAILED OUTCOME DATA

APPENDIX 5 VALIDITY OF OUTCOME MEASURES

APPENDIX 6 SUMMARY OF OPEN-LABEL EXTENSION STUDY

APPENDIX 7 SUMMARY AND APPRAISAL OF MANUFACTURER SUBMITTED NETWORK META-ANALYSIS

REFERENCES

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Bookshelf ID: NBK349378

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