U.S. flag

An official website of the United States government

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

McIntosh B, Mierzwinski-Urban M. General Anesthesia and Deep Sedation for Dental Treatments in Children: A Review of Clinical Effectiveness and Guidelines [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2017 Mar 6.

Cover of General Anesthesia and Deep Sedation for Dental Treatments in Children: A Review of Clinical Effectiveness and Guidelines

General Anesthesia and Deep Sedation for Dental Treatments in Children: A Review of Clinical Effectiveness and Guidelines [Internet].

Show details

Appendix 2Characteristics of Included Publications

AuthorDesignPopulationInterventionsOutcomes
Antunes et al, 201611Prospective cohort
Clinicians: 4
Sites: NR
Location: Brazil
  • <4 years
  • Underwent ECC treatment
  • ASA-1
  • N = 50
  • No sedative (n = 17)
  • Moderate sedation with midazolam (n = 16)
  • Moderate sedation with midazolam and ketamine (n = 13)
  • GA (n = 4)
  • Ohio State University Behavioral Rating Scale
  • To time to co-operative behavior (sum of OSUBRS scores = 5)
Inverso et al, 201612Prospective cohort
  • Clinicians: 79
  • Sites: 58
  • Location: US
  • <21 years
  • Undergoing third molar extraction
  • ASA-I (89.2%)
  • ASA-II (10.6%)
  • ASA-III (0.2%)
  • ASA-IV (<0.1%)
  • ASA-V (<0.1%)
  • N = 29,548
  • Moderate sedation (n = 3,109)
  • Deep sedation/GA (n = 26,439)
  • Vomiting (with or without aspiration):
    • during induction and/or maintenance
    • during recovery
  • Laryngospasm
  • Bronchospasm
  • Respiratory arrest and/or hypoventilation requiring intervention
  • New cardiac dysrhythmia requiring intervention
  • Syncope
  • Seizure
  • Neurologic impairment
  • Prolonged emergence from anesthesia
  • Peripheral vascular injury
Silay et al, 201313Prospective cohort
  • Clinicians: NR
  • Sites: NR
  • Location: Turkey
  • 2 to 12 years
  • Dental procedures or minor oral surgeries
  • ASA-1
  • N = 105
  • Conscious sedation with IV midazolam (n = 47)
  • GA (n = 58)
  • Initial and repeated doses of anesthetic and sedative agents administered
  • Oxygen saturation
  • Pulse rate
  • Procedures performed
  • Duration of the procedures
  • Patients’ behaviour patterns
  • Procedural comfort for the physicians.
Fuhrer et al, 200914Retrospective cohort
  • Clinicians: 3
  • Sites: 1
  • Location: US
  • <36 months
  • Undergoing ECC treatment
  • N = 80
  • Conscious sedation with choral hydrate, hydroxyzine, nitrous oxide, and protective stabilization (n = 39).
  • GA (n = 41)
  • Frankl behavioral scale
  • Number of teeth involved in procedure

ASA = American Society of Anesthesiologists; ECC = early childhood caries; GA = general anesthesia; IV = intravenous; n = number of patients in the treatment group; N = total number of patients; NR = not reported; OSUBRS = Ohio State University Behavioral Rating Scale; US = United States

Table 7Characteristics of Included Guidelines

ObjectivesMethodology
Intended users/Target populationIntervention and Practice ConsideredEvidence collectionEvidence Quality and StrengthRecommendatio ns developmentGuideline Validation
Association of Paediatric Anaesthetists of Great Britain and Ireland17
  • Intended users: dentists, anesthetists, registered nurses, dental nurses and operating department assistants/practitioners, parents/care givers
  • Targeted population: children and young people who are referred for dental extractions under GA
  • General anesthesia for dental procedures
  • Search of electronic databases
  • Manual searches of guidelines
  • Studies: meta-analyses, systemic reviews, RCTs, clinical trials, cohort studies, case series
  • Population: aged 0 to 18 years
  • Intervention: general anesthesia
  • SIGN methodology
  • Not reported consultation
  • Stakeholder
UK National Clinical Guidelines in Paediatric Dentistry18
  • Intended users: not reported
  • Targeted population: Pediatric dental patients requiring tooth extraction
  • General anesthesia for dental procedures
  • Search of one electronic database
  • Not reported consultation
  • Not reported
  • Stakeholder

GA = general anesthesia; RCT = randomized controlled trials; SIGN = Scottish Intercollegiate Guidelines Network

Copyright © 2017 Canadian Agency for Drugs and Technologies in Health.

The copyright and other intellectual property rights in this document are owned by CADTH and its licensors. These rights are protected by the Canadian Copyright Act and other national and international laws and agreements. Users are permitted to make copies of this document for non-commercial purposes only, provided it is not modified when reproduced and appropriate credit is given to CADTH and its licensors.

Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

Bookshelf ID: NBK475602
Contents

Views

  • PubReader
  • Print View
  • Cite this Page
  • PDF version of this title (812K)

Other titles in this collection

Recent Activity

ClearTurn OffTurn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...