NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
This resource includes articles, fact sheets, and research summaries from Informed Health Online, the patient-centered health information portal of Germany's national health information website, Institute for Quality and Efficiency in Health Care.
Contents
Topics
Abdominal aortic aneurysm
Acne
Acute bronchitis
Acute cystitis
Acute pancreatitis
Allergic contact dermatitis
Allergies
Allergies to animals
Alzheimer's disease
Ankle fractures
Ankle sprains
Asthma
- Overview
- Learn more: Symptoms and diagnosis
- Learn more: Exercise-induced asthma
- Learn more: Immunotherapy for allergic asthma
- Learn more: Medication for people with asthma
- Learn more: Non-drug interventions for asthma
- Learn more: Asthma in pregnancy
- Learn more: Coronavirus: What to be aware of if you have asthma
- Learn more: Information for parents
Atrial fibrillation
Attention deficit hyperactivity disorder (ADHD)
Bacterial vaginosis
Bedwetting
Benign enlarged prostate
Benign paroxysmal positional vertigo
Boils and carbuncles
Brain aneurysm
Breast cancer
- Overview
- Research summaries: Aromatase inhibitors for early-stage breast cancer
- Research summaries: Aromatase inhibitors as upfront therapy for early-stage breast cancer
- Research summaries: Early-stage breast cancer: Switching to aromatase inhibitors after tamoxifen
- Research summaries: Aromatase inhibitors in the extended treatment of early-stage breast cancer
- Learn more: Risk factors for breast cancer
- Learn more: What role does breast density play?
- Learn more: Recurrent non-metastatic breast cancer
- Learn more: The breast cancer screening program in Germany
- Learn more: Breast cancer: Treating lymphedema
- Learn more: Breast cancer: How exercise can help
- Learn more: Early-stage breast cancer: Does it make sense to have chemotherapy?
- Learn more: Early-stage breast cancer: When is biomarker testing helpful?
Canker sores (mouth ulcers)
Carpal tunnel syndrome
Cataracts
Cervical cancer
- Overview
- Learn more: Human papillomaviruses (HPV)
- Learn more: Cervical cancer: Screening and prevention
- Learn more: Abnormal cells on the cervix (dysplasia)
- Learn more: HPV vaccine to prevent cervical cancer
- Learn more: How is cervical cancer treated?
- Research summaries: Cervical cancer: What are the benefits of HPV tests for cervical screening?
Chronic kidney disease
Chronic obstructive pulmonary disease (COPD)
Chronic wounds
Cold sores
Colorectal cancer
- Overview
- Learn more: Signs of colorectal cancer
- Learn more: Stool test: Information for women
- Learn more: Stool test: Information for men
- Learn more: Colonoscopy: Information for women
- Learn more: Colonoscopy: Information for men
- Learn more: Preventing colorectal cancer: What role does lifestyle play?
- Research summaries: Colorectal cancer in the family: Are screening tests for people under the age of 55 worth it?
Common colds
Contraception
Coronary artery disease
- Overview
- Learn more: Complications of coronary artery disease
- Learn more: Signs of a heart attack
- Learn more: What can I do to keep my heart healthier?
- Learn more: Medication for the long-term treatment of coronary artery disease
- Learn more: Influence of coronary artery disease on mental health and everyday life
Croup
Deep vein thrombosis (DVT)
Depression
- Overview
- Research summaries: Can St. John’s wort products help?
- Research summaries: Effective treatments for depression and coronary artery disease
- Research summaries: Can sports and exercise help?
- Learn more: Types of depression
- Learn more: What is burnout?
- Learn more: Depression in children and teenagers
- Learn more: Treatments for depression
- Learn more: How effective are antidepressants?
- Learn more: How effective is psychological treatment?
- Learn more: Experiences with antidepressants
- Learn more: Strategies for family and friends
Diarrhea
Dislocated kneecap
Diverticular disease and diverticulitis
Drug allergies
Drugs assessed by IQWiG
Dust mite allergies
Eczema
- Overview
- Learn more: Skin care for eczema
- Learn more: Steroids and other topical medications
- Learn more: Light therapy and oral medications
- Research summaries: Eczema: Can eliminating particular foods help?
- Research summaries: Eczema in children: Can prebiotics or probiotics help prevent it?
- Research summaries: What effect does diet during pregnancy or breastfeeding have on a child's risk of developing eczema?
Endometriosis
- Overview
- Learn more: The symptoms of endometriosis
- Learn more: What causes endometriosis?
- Learn more: Diagnosing endometriosis
- Learn more: Treatment options for endometriosis
- Learn more: My partner has endometriosis – what does that mean for me?
- Research summaries: Surgery: What are the advantages and disadvantages of having hormone therapy too?
Enlarged hemorrhoids
Enlarged tonsils and adenoids
Epilepsy
Erysipelas and cellulitis
Falls in older people
Fever in children
Fibromyalgia
- Overview
- Learn more: What is known about the causes of fibromyalgia?
- Learn more: Understanding chronic pain
- Learn more: Exercise, relaxation and stress management
- Learn more: Medication for the treatment of fibromyalgia
- Learn more: Multimodal pain management and cognitive behavioral therapy
- Learn more: Complementary and alternative treatments
Flu
Food allergies
Frozen shoulder
Gastritis
Generalized anxiety disorder
Genital herpes
Gestational diabetes
Gingivitis and periodontitis
Glaucoma
Golfer's elbow
Gout
Hair loss in chemotherapy
Hay fever
Health care in Germany
Hearing loss and deafness
Heart failure
Heart valve diseases
Heavy periods
Hemophilia
Hepatitis B
Hernias
High blood pressure
- Overview
- Learn more: Lowering blood pressure without medication
- Learn more: What medications are used to treat high blood pressure?
- Learn more: When is taking medication for high blood pressure a good idea?
- Learn more: Tips for reducing your salt intake
- Learn more: Coronavirus: What to be aware of if you have high blood pressure
High cholesterol
Infertility
Ingrown toenail
Insect venom allergies
Insomnia
Irritable bowel syndrome
Kidney stones
Lactose intolerance
Lazy eye (amblyopia) in children
Localized prostate cancer
Low back pain
- Overview
- Learn more: Low back pain: Signs of serious problems
- Learn more: Why movement is so important for back pain
- Learn more: Relaxation techniques for back pain
- Learn more: What role does medication play in the treatment of non-specific back pain?
- Learn more: Multimodal pain management and cognitive behavioral therapy
- Learn more: Passive treatments: Massages, heat and manual therapy
- Learn more: Living with chronic low back pain
- Research summaries: Can exercise prevent recurrent low back pain?
Measles
Melanoma
Menopause
Metastatic breast cancer
- Overview
- Learn more: Diagnostic tests for metastatic breast cancer
- Learn more: Treatments and possible consequences
- Learn more: Pain management in metastatic breast cancer
- Learn more: Living with metastatic breast cancer
- Learn more: Information for partners
- Learn more: Saying goodbye
- Learn more: Finding support in Germany - formalities and financial aspects
- Research summaries: Advanced breast cancer: Does group therapy help?
Middle ear infection
Migraine
Misaligned teeth and jaws
Mumps
Neck pain
Non-melanoma skin cancer
Obsessive-compulsive disorder
Obstructive sleep apnea
Oral thrush
Osteoarthritis
Osteoarthritis of the knee
- Overview
- Learn more: What can I do to strengthen my knees?
- Learn more: Which painkillers are effective?
- Learn more: Do knee injections help?
- Learn more: What can I expect from knee replacement surgery?
- Learn more: What different types of knee implants are there?
- Learn more: What can you expect before and after surgery?
- Research summaries: Does arthroscopy help in osteoarthritis of the knee?
Osteoporosis
Outer ear infection
Parkinson’s disease
Patellofemoral pain syndrome (runner’s knee)
Pelvic organ prolapse
Period pain
Pneumonia
Post-traumatic stress disorder (PTSD)
- Overview
- Learn more: Psychological treatments and other interventions for post-traumatic stress disorder
- Learn more: Medication for post-traumatic stress disorder
- Learn more: What kind of support is helpful immediately after a traumatic event?
- Research summaries: Can early psychological treatment prevent post-traumatic stress disorder?
Pregnancy and birth
- Overview
- Learn more: Why is a test offered for the detection of serious heart problems in newborns?
- Learn more: Depression after childbirth – What can help?
- Learn more: Reflux in babies
- Research summaries: Do all pregnant women need to take iron supplements?
- Research summaries: What are the benefits of routinely screening for bacteria in the urine of pregnant women?
- Research summaries: What is the benefit of determining the Rh factor before birth?
- Research summaries: What is the benefit of screening for B streptococcus bacteria during pregnancy?
- Research summaries: Before preterm birth: What do steroids do?
- Research summaries: When does labor need to be induced?
- Research summaries: Cesarean sections: What are the pros and cons of regional and general anesthetics?
- Learn more: Weight gain in pregnancy
- Research summaries: What helps women lose weight again after having a baby?
- Research summaries: Depression after childbirth: Can psychosocial and psychological treatment approaches help?
- Research summaries: What are the benefits of screening for severe combined immunodeficiency (SCID) in newborns?
- Research summaries: Expressing breast milk: Are some methods better than others?
- Learn more: What helps reduce nausea in pregnancy?
- Learn more: HIV test in pregnancy
- Learn more: Ultrasound scans in pregnancy
- Learn more: What can be done if a baby is likely to be born too early?
- Learn more: When your baby’s due date has passed
- Learn more: Managing pain during childbirth
- Learn more: Epidurals and painkillers for labor pain relief
Premature ejaculation
Premenstrual syndrome
Pressure ulcers
Psoriasis
Rheumatoid arthritis
- Overview
- Learn more: How is early rheumatoid arthritis diagnosed?
- Learn more: Medication to prevent joint damage
- Learn more: Painkillers for rheumatoid arthritis
- Learn more: Daily living aids for people with rheumatoid arthritis
- Learn more: Exercise and sports for rheumatoid arthritis
- Learn more: Living and dealing with fatigue
- Learn more: Everyday life with rheumatoid arthritis
- Research summaries: Can psychological treatment and patient education help in rheumatoid arthritis?
Rosacea
Rubella (German measles)
Scarlet fever
Seborrheic dermatitis
Shoulder pain
Slipped disc
Small objects in the eye
Smoking
Stroke
Styes and chalazia (inflammation of the eyelid)
Surgery
- Overview
- Learn more: Before surgery: Getting information and making a decision
- Learn more: What can help relieve anxiety before surgery?
- Learn more: What helps children cope with anxiety before an operation?
- Learn more: Pain after surgery
- Research summaries: Can quitting smoking before surgery prevent complications?
Tendon overuse injuries (tendinopathy)
Tennis elbow
Tick bites
Tinea versicolor
Tonsillitis
Type 1 diabetes
- Overview
- Learn more: Hyperglycemia and hypoglycemia in type 1 diabetes
- Learn more: Types of insulin therapy
- Learn more: Types of insulin
- Learn more: Forms of insulin delivery
- Learn more: Measuring sugar levels in blood and urine yourself
- Research summaries: Can continuous glucose monitoring improve insulin therapy?
Type 2 diabetes
Using medication
- Overview
- Research summaries: Dietary supplements: Can they also be harmful?
- Research summaries: Painkillers: How common are severe side effects of NSAIDs?
- Learn more: Oral medications
- Learn more: Topical medications
- Learn more: Injections, suppositories and other dosage forms
- Learn more: Managing medication for long-term conditions
- Learn more: Children and medications: Getting the dose right
- Learn more: Using antibiotics correctly and avoiding resistance
- Learn more: The safe use of over-the-counter painkillers
- Research summaries: What can help when trying to stop taking sleeping pills and sedatives?
Uterine fibroids
Vaginal yeast infection (thrush)
Varicose veins
Vocal nodules
Wrist injuries
In brief
The human body
- Bone structure
- Causes and signs of edema
- Foot deformities
- How are genes passed on?
- How are sex cells made (meiosis)?
- How can I get enough calcium?
- How can I get enough iron?
- How do bowel movements work?
- How do cancer cells grow and spread?
- How do hands work?
- How do joints work?
- How do lungs work?
- How do most cells divide (mitosis)?
- How do the female sex organs work?
- How do the kidneys work?
- How do the tonsils work?
- How does our sense of balance work?
- How does our sense of taste work?
- How does skin work?
- How does the ankle work?
- How does the blood circulatory system work?
- How does the brain work?
- How does the ear work?
- How does the eye work?
- How does the gallbladder work?
- How does the heart work?
- How does the immune system work?
- How does the intestine work?
- How does the knee work?
- How does the larynx work?
- How does the liver work?
- How does the menstrual cycle work?
- How does the nervous system work?
- How does the pancreas work?
- How does the periodontium work?
- How does the pituitary gland work?
- How does the prostate work?
- How does the shoulder work?
- How does the spine work?
- How does the stomach work?
- How does the thyroid gland work?
- How does the tongue work?
- How does the urinary system work?
- How is body temperature regulated and what is fever?
- How our teeth and jaws work together
- Structure of the nails
- The innate and adaptive immune systems
- The lymphatic system
- What are blood clots and what causes them?
- What are ligaments?
- What are microbes?
- What are tendons and tendon sheaths?
- What are the organs of the immune system?
- What do the male sex organs do?
- What does blood do?
- What happens when you age?
- What is an inflammation?
- What is cholesterol and how does arteriosclerosis develop?
- What is the structure of hair and how does it grow?
- What is “normal” sleep?
Treatments and diagnostic tests
- A guide to psychotherapy in Germany: Where can I find help?
- Benefits and risks of screening tests
- Biologics and biosimilars
- Bladder training
- Brachytherapy
- Cancer: What do the codes in the doctor’s letter mean?
- Cardiopulmonary resuscitation (CPR): What you need to know
- Children and sun – Practical information for parents
- Cognitive behavioral therapy
- Disease management program for type 1 diabetes in Germany
- External radiotherapy
- Fasting
- Giving mouth-to-mouth resuscitation
- Glucose tolerance tests: What exactly do they involve?
- Harvesting blood stem cells for transplantation
- Hay fever or COVID-19: How do the symptoms differ?
- Hospital quality assurance in Germany: The areas of care in 2014
- How can you protect yourself from respiratory infections?
- How can you self-manage and adjust anticoagulants in the long term?
- How do I apply for pulmonary rehabilitation in Germany?
- How do ultrasound examinations work?
- How do you use an automated external defibrillator (AED)?
- How does chemotherapy work?
- How does dialysis work?
- How is diabetes mellitus diagnosed?
- How much sun is too much?
- Hysterectomy (surgical removal of the womb)
- Joint aspiration
- Medication list
- Mouth sores – What can you do yourself?
- “Off-label use”: What to be aware of
- Pelvic floor tips for everyday life
- Pelvic floor training
- Personalized medicine
- Physical therapy
- Screening – what might help you decide
- Stem cell transplantation for treating cancer
- Types of dentures
- Understanding tests used to detect bone problems
- Understanding thyroid tests
- Understanding urine tests
- Using eye drops properly
- Using steroids correctly and avoiding side effects
- Vaccinations
- What are blood thinners (anti-clotting medication) and how are they used?
- What are dietary supplements?
- What are disease management programs (DMPs)?
- What are immunological tests?
- What do ear examinations involve?
- What does genetic testing involve?
- What happens during a PET scan?
- What happens during a biopsy?
- What happens during a gastroscopy?
- What happens during a lumbar puncture (spinal tap)?
- What happens during a neurological examination?
- What happens during a skin examination?
- What happens during a sleep study?
- What happens during an electroencephalogram (EEG)?
- What happens during cardiac catheterization?
- What is an echocardiogram?
- What is an electrocardiogram (ECG)?
- What is blood pressure and how is it measured?
- What is occupational therapy?
- What is overdiagnosis?
- What is pulmonary rehabilitation?
- What is speech therapy?
- What is voice therapy?
- What kind of lung function tests are there and what do they involve?
- What kinds of allergy tests are there?
- What kinds of eye examinations are there?
- What kinds of massage are there?
- Which screening tests are paid for by statutory health insurance funds in Germany?
Early-benefit assessment of medications
Abemaciclib (EU: Verzenios, U.S.: Verzenio) and aromatase inhibitors for the treatment of advanced breast cancer
Abemaciclib (EU: Verzenios, U.S.: Verzenio) and fulvestrant for the treatment of advanced breast cancer
Abiraterone acetate (Zytiga) for the treatment of metastatic prostate cancer
Alectinib (Alecensa) for the treatment of advanced lung cancer
Alirocumab (Praluent) for the treatment of hypercholesterolemia and mixed dyslipidemia
Andexanet alfa (EU: Ondexxya, U.S.: Andexxa) for the treatment of major bleeding
Apalutamide (Erleada) for the treatment of metastatic prostate cancer
Apalutamide (Erleada) for the treatment of prostate cancer
Apremilast (Otezla) for the treatment of aphthous ulcers in Behçet's disease
Asfotase alfa (Strensiq) for the treatment of hypophosphatasia
Atezolizumab (Tecentriq) for the first-line treatment of advanced lung cancer
Atezolizumab (Tecentriq) for the treatment of advanced bladder cancer (urothelial carcinoma)
Atezolizumab (Tecentriq) for the treatment of advanced breast cancer
Atezolizumab (Tecentriq) for the treatment of advanced lung cancer
Avelumab (Bavencio) for the treatment of advanced renal cell cancer
Avelumab (Bavencio) for the treatment of metastatic Merkel cell carcinoma
Axitinib (Inlyta) for renal cell cancer
Baricitinib (Olumiant) in the treatment of rheumatoid arthritis
Belimumab (Benlysta) for the treatment of systemic lupus erythematosus in children and teenagers
Benralizumab (Fasenra) for the treatment of severe asthma
Bezlotoxumab (Zinplava) for the treatment of Clostridium difficile infections
Binimetinib (Mektovi) and encorafenib (Braftovi) for the treatment of advanced melanoma
Bosutinib (Bosulif) for the treatment of chronic myeloid leukemia
Brigatinib (Alunbrig) for the treatment of advanced non-small-cell lung cancer
Brivaracetam (Briviact) for the treatment of epilepsy
Brodalumab (EU: Kyntheum, U.S.: Siliq) for the treatment of psoriasis
Cabozantinib (Cabometyx) for the treatment of advanced hepatocellular carcinoma (liver cancer)
Cabozantinib (Cabometyx) for the treatment of advanced renal cell cancer
Cannabis sativa (Sativex) for the treatment of spasticity due to multiple sclerosis
Carfilzomib (Kyprolis) for the treatment of multiple myeloma
Cariprazine (Reagila) for the treatment of schizophrenia
Cemiplimab (Libtayo) for the treatment of advanced non-melanoma skin cancer
Ceritinib (Zykadia) for the treatment of advanced lung cancer
Cladribine (Mavenclad) for the treatment of multiple sclerosis
Cobicistat (Tybost) for the treatment of HIV-1 infection in teenagers
Crizotinib (Xalkori) for advanced lung cancer
Dabrafenib (Tafinlar) and trametinib (Mekinist) for the treatment of advanced melanoma
Dacomitinib (Vizimpro) for the treatment of advanced lung cancer
Damoctocog alfa pegol (Jivi) for the treatment of hemophilia A
Dapagliflozin (EU: Forxiga, U.S.: Farxiga) for the treatment of type 2 diabetes
Daratumumab (Darzalex) for the treatment of multiple myeloma
- Overview
- Learn more: Daratumumab (Darzalex) as first-line treatment in combination with bortezomib, melphalan and prednisone if a stem cell transplantation is not an option
- Learn more: Daratumumab (Darzalex) for the treatment of multiple myeloma in adults who have already had treatment
- Learn more: Daratumumab (Darzalex) as first-line treatment in combination with lenalidomide and dexamethasone if a stem cell transplantation is not an option
Darolutamide (Nubeqa) for the treatment of prostate cancer
Dimethyl fumarate (Skilarence) for the treatment of psoriasis
Dolutegravir (Tivicay) for HIV
Dolutegravir / lamivudine (Dovato) for the treatment of type 1 HIV
Dolutegravir / rilpivirine (Juluca) for the treatment of HIV
Doravirine (Pifeltro) for the treatment of HIV
Doravirine / lamivudine / tenofovir disoproxil fumarate (Delstrigo) for the treatment of HIV
Dulaglutide (Trulicity) for the treatment of type 2 diabetes
Dupilumab (Dupixent) for the treatment of chronic rhinosinusitis with nasal polyps
Dupilumab (Dupixent) for the treatment of eczema
Dupilumab (Dupixent) for the treatment of severe asthma
Durvalumab (Imfinzi) for the treatment of advanced lung cancer
Elbasvir / grazoprevir (Zepatier) for hepatitis C
Elotuzumab (Empliciti) for multiple myeloma
Elvitegravir / cobicistat / emtricitabine / tenofovir disoproxil (Stribild) for the treatment of HIV in teenagers
Emicizumab (Hemlibra) for the treatment of hemophilia A
Empagliflozin (Jardiance) for type 2 diabetes
Empagliflozin / Metformin (Synjardy) for type 2 diabetes
Encorafenib (Braftovi) for the treatment of metastatic colorectal cancer (bowel cancer)
Enzalutamide (Xtandi) for the treatment of advancing prostate cancer
- Overview
- Learn more: Enzalutamide for the treatment of metastatic prostate cancer if hormone blockers are no longer effective
- Learn more: Enzalutamide for the treatment of metastatic prostate cancer during or after chemotherapy
- Learn more: Enzalutamide for the treatment of non-metastatic prostate cancer
Erenumab (Aimovig) for the prevention of migraine
Etelcalcetide (Parsabiv) for the treatment of hyperparathyroidism (overactive parathyroid gland)
Evolocumab (Repatha) for the treatment of hypercholesterolemia and mixed dyslipidemia
Fingolimod (Gilenya) for the treatment of multiple sclerosis
- Overview
- Learn more: Fingolimod (Gilenya) for adults with MS who have had treatment with glatiramer acetate
- Learn more: Fingolimod (Gilenya) for adults with rapidly evolving relapsing-remitting multiple sclerosis
- Learn more: Fingolimod (Gilenya) for the treatment of MS in children and teenagers who have had treatment with glatiramer acetate or interferon beta
Fixed combination of saxagliptin and metformin (Komboglyze) for the treatment of type 2 diabetes
Fixed-dose combination ceftolozane / tazobactam (Zerbaxa) for the treatment of complicated intra-abdominal infections
Fixed-dose combination ceftolozane / tazobactam (Zerbaxa) for the treatment of complicated urinary tract infections and acute pyelonephritis
Fixed-dose combination of ceftolozane / tazobactam (Zerbaxa) for the treatment of hospital-acquired pneumonia
Fixed-dose combination of dapagliflozin and metformin (Xigduo) for the treatment of type 2 diabetes
Fixed-dose combination of empagliflozin / linagliptin (Glyxambi) for the treatment of type 2 diabetes
Fixed-dose combination of ertugliflozin and sitagliptin (Steglujan) for the treatment of type 2 diabetes
Fixed-dose combination of fluticasone furoate / umeclidinium / vilanterol (Trelegy Ellipta) for the treatment of COPD
Fixed-dose combination of insulin glargine / lixisenatide (Suliqua) for the treatment of type 2 diabetes
Fixed-dose combination of lumacaftor / ivacaftor (Orkambi) for the treatment of cystic fibrosis in children
Fixed-dose combination with elvitegravir (Genvoya) for the treatment of HIV
Fostamatinib (Tavlesse) for the treatment of chronic immune thrombocytopenia
Fremanezumab (Ajovy) for the prevention of migraine
Galcanezumab (Emgality) for the treatment of migraine
Glecaprevir / pibrentasvir (Maviret) for the treatment of chronic hepatitis C
Glycopyrronium bromide (Sialanar) for the treatment of chronic pathological drooling
Guselkumab (Tremfya) for the treatment of psoriasis
Hydrocortisone (Alkindi) for the treatment of adrenal insufficiency
Ibrutinib (Imbruvica) for the treatment of Waldenström's macroglobulinemia
Ibrutinib (Imbruvica) for the treatment of chronic lymphocytic leukemia (CLL)
- Overview
- Learn more: Ibrutinib (Imbruvica) as monotherapy for people who have had treatment for CLL and are unable to have further chemotherapy
- Learn more: Ibrutinib (Imbruvica) in combination therapy for people who have had treatment for CLL and are able to have further chemotherapy
- Learn more: Ibrutinib (Imbruvica) in combination therapy for people who have not had treatment for CLL
Idelalisib (Zydelig) for chronic lymphocytic leukemia (CLL)
Ingenol mebutate (Picato) for actinic keratosis
Insulin degludec (Tresiba) for the treatment of type 2 diabetes in adults
Insulin degludec / liraglutide (Xultophy) for type 2 diabetes in adults
Ipilimumab (Yervoy) for the treatment of melanoma
Ipilimumab (Yervoy) in combination with nivolumab (Opdivo) for the first-line treatment of advanced renal cell cancer
Ivacaftor (Kalydeco) for the treatment of cystic fibrosis
- Overview
- Learn more: Ivacaftor (Kalydeco) for the treatment of cystic fibrosis in children who have a G551D mutation
- Learn more: Ivacaftor (Kalydeco) for the treatment of cystic fibrosis in teenagers and adults who have a G551D mutation
- Learn more: Ivacaftor (Kalydeco) for the treatment of cystic fibrosis in children and teenagers who have an R117H mutation
- Learn more: Ivacaftor (Kalydeco) for the treatment of cystic fibrosis in adults who have an R117H mutation
- Learn more: Ivacaftor (Kalydeco) with tezacaftor / ivacaftor (Symkevi) for the treatment of cystic fibrosis in people aged 12 years and over who have a homozygous F508del mutation
Ixekizumab (Taltz) for the treatment of axial spondyloarthritis
Ixekizumab (Taltz) for the treatment of psoriasis
- Overview
- Learn more: Ixekizumab (Taltz) for adults with plaque psoriasis who are able to have systemic treatment
- Learn more: Ixekizumab (Taltz) for adults with plaque psoriasis who are unable to have a different systemic treatment
- Learn more: Ixekizumab (Taltz) as a first treatment with biological drugs for active psoriatic arthritis in adults
Larotrectinib (Vitrakvi) for the treatment of advanced tumors
Ledipasvir / sofosbuvir (Harvoni) for the treatment of chronic hepatitis C in teenagers
Lenvatinib (EU: Kisplyx, U.S.: Lenvima) for advanced renal cell cancer
Lenvatinib (Lenvima) for the treatment of advanced thyroid cancer
Lenvatinib (Lenvima) for the treatment of hepatocellular carcinoma (liver cancer)
Lisdexamfetamine (Elvanse / Elvanse Adult, Vyvanse) for the treatment of ADHD
Lonoctocog alfa (Afstyla) for hemophilia A
Lorlatinib (Lorviqua, Lorbrena) for the treatment of advanced lung cancer
Macitentan (Opsumit) for pulmonary arterial hypertension
Melatonin (Slenyto) for the treatment of insomnia
Mepolizumab (Nucala) for the treatment of severe asthma
Naldemedine (Rizmoic) for the treatment of opioid-induced constipation
Nalmefene (Selincro) for alcohol dependency
Neratinib (Nerlynx) for the treatment of breast cancer
Nintedanib (Ofev) for the treatment of idiopathic pulmonary fibrosis
Niraparib (Zejula) for the treatment of ovarian cancer
Nivolumab (Opdivo) for Hodgkin's lymphoma
Nivolumab (Opdivo) for head and neck cancer
Nivolumab (Opdivo) for the treatment of advanced urothelial carcinoma
Nivolumab (Opdivo) for the treatment of melanoma
Nonacog beta pegol (Refixia) for the treatment of hemophilia B
Ocrelizumab (Ocrevus) for the treatment of multiple sclerosis
Ocriplasmin (Jetrea) for the treatment of vitreomacular traction
Olaparib (Lynparza) for the treatment of advanced breast cancer
Olaparib (Lynparza) for the treatment of ovarian cancer
Opicapone (Ongentys) for Parkinson's disease
Osimertinib (Tagrisso) for the treatment of advanced lung cancer with a T790M mutation
Osimertinib (Tagrisso) for the treatment of advanced lung cancer with activating EGFR mutations
Ozanimod (Zeposia) for the treatment of multiple sclerosis
Palbociclib (Ibrance) for the treatment of advanced breast cancer
Patiromer (Veltassa) for the treatment of hyperkalemia
Pembrolizumab (Keytruda) for advanced lung cancer
Pembrolizumab (Keytruda) for the treatment of Hodgkin’s lymphoma
Pembrolizumab (Keytruda) for the treatment of advanced bladder cancer (urothelial carcinoma)
Pembrolizumab (Keytruda) for the treatment of advanced head and neck cancer
- Overview
- Learn more: Pembrolizumab (Keytruda) for the treatment of advanced head and neck cancer in adults who have had previous treatment
- Learn more: Pembrolizumab (Keytruda) used on its own for the treatment of advanced, incurable head and neck cancer
- Learn more: Pembrolizumab (Keytruda) in combination with chemotherapy for the treatment of advanced, incurable head and neck cancer
Pembrolizumab (Keytruda) for the treatment of advanced renal cell cancer
Pembrolizumab (Keytruda) for the treatment of melanoma
Pembrolizumab (Keytruda) in combination with chemotherapy for the treatment of advanced lung cancer
Perampanel (Fycompa) for the treatment of epilepsy
Pertuzumab (Perjeta) for the treatment of breast cancer
Pomalidomide (EU: Imnovid, U.S.: Pomalyst) for the treatment of multiple myeloma
Radium-223 dichloride (Xofigo) for the treatment of advanced prostate cancer
Ramucirumab (Cyramza) for the treatment of advanced liver cancer
Ramucirumab (Cyramza) for the treatment of metastatic lung cancer
Ravulizumab (Ultomiris) for the treatment of atypical hemolytic uremic syndrome
Ravulizumab (Ultomiris) for the treatment of paroxysmal nocturnal hemoglobinuria
Reslizumab (EU: Cinqaero, U.S.: Cinqair) for severe asthma
Ribociclib (Kisqali) for the treatment of advanced breast cancer
- Overview
- Learn more: Ribociclib (Kisqali) as part of first-line hormone therapy for advanced breast cancer in women after menopause
- Learn more: Ribociclib (Kisqali) as part of hormone therapy in subsequent treatment of advanced breast cancer in women before and during menopause
- Learn more: Ribociclib (Kisqali) as part of subsequent hormone therapy for advanced breast cancer in women after menopause
Riociguat (Adempas) for the treatment of chronic thromboembolic pulmonary hypertension (high blood pressure)
Risankizumab (Skyrizi) for the treatment of psoriasis
Rolapitant (EU: Varuby, U.S.: Varubi) for the prevention of nausea and vomiting in chemotherapy
Romosozumab (Evenity) for the treatment of osteoporosis
Ropeginterferon alfa-2b (Besremi) for the treatment of polycythemia vera
Rucaparib (Rubraca) for the treatment of advanced ovarian cancer
Rurioctocog alfa pegol (Adynovi) for the treatment of hemophilia A
Sarilumab (Kevzara) for the treatment of rheumatoid arthritis
Secukinumab (Cosentyx) for psoriasis
Semaglutide (Ozempic) for the treatment of type 2 diabetes
Siponimod (Mayzent) for the treatment of multiple sclerosis
Sitagliptin (Januvia or Xelevia) for type 2 diabetes
Sofosbuvir (Sovaldi) for the treatment of chronic hepatitis C
- Overview
- Learn more: Sofosbuvir (Sovaldi) for the treatment of chronic hepatitis C (genotype 2) in adults
- Learn more: Sofosbuvir (Sovaldi) for the first-line treatment of chronic hepatitis C (genotype 2 or 3) in teenagers
- Learn more: Sofosbuvir (Sovaldi) for the follow-up treatment of chronic hepatitis C (genotype 2 or 3) in teenagers
Sofosbuvir / velpatasvir (Epclusa) for chronic hepatitis C
Sofosbuvir / velpatasvir / voxilaprevir (Vosevi) for the treatment of chronic hepatitis C
Solriamfetol (Sunosi) for the treatment of narcolepsy
Sonidegib (Odomzo) for the treatment of non-melanoma skin cancer
Talazoparib (Talzenna) for the treatment of advanced breast cancer
Tezacaftor / ivacaftor (Symkevi) for the treatment of cystic fibrosis
The fixed-dose combination trifluridine / tipiracil (Lonsurf) for the treatment of advanced gastric (stomach) cancer
Tildrakizumab (EU: Ilumetri, U.S.: Ilumya) for the treatment of psoriasis
Tivozanib (Fotivda) for the treatment of advanced renal cell cancer
Tofacitinib (Xeljanz) for the treatment of psoriasis with inflammation of the joints (psoriatic arthritis)
Tofacitinib (Xeljanz) for the treatment of rheumatoid arthritis
Tofacitinib (Xeljanz) for the treatment of ulcerative colitis
Trametinib (Mekinist) plus dabrafenib (Tafinlar) for the treatment of advanced lung cancer
Trastuzumab emtansine (Kadcyla) for the treatment of early-stage breast cancer
Trifluridine / tipiracil (Lonsurf) for the treatment of metastatic colorectal cancer
Turoctocog alfa pegol (Esperoct) for the treatment of hemophilia A
Upadacitinib (Rinvoq) for the treatment of rheumatoid arthritis
Vandetanib (Caprelsa) for aggressive thyroid cancer
Venetoclax (EU: Venclyxto, U.S.: Venclexta) for the treatment of chronic lymphocytic leukemia (CLL)
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