Critical Appraisal of Primary Studies

Calvin Young; Dr. Alison Sinclair; Cody Black; Elijah Herington; Elijah Herington; Dr. Maxwell Smith; Carolyn Spry; Kaitryn Campbell; Bert Dolcine

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Young C, Sinclair A, Black C, et al. Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Dec. (CADTH Optimal Use Report, No. 9.3b.)

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Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment [Internet].

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Appendix 8Critical Appraisal of Primary Studies

Table 18Cochrane Risk of Bias Assessment for Included Randomized Controlled Trials

	Selection Bias		Performance Bias	Detection Bias	Attrition Bias	Reporting Bias	Other Bias
Study Citation	Risk of Bias in Sequence Generation	Risk of Bias in Allocation Concealment	Risk of Bias in Binding of Participants and Personnel	Risk of Bias in Binding of Outcome Assessment	Risk of Bias From Incomplete Outcome Data	Risk of Bias From Selective Outcome Reporting	Risk of Bias From Other Biases
Engel (2015)⁵⁴	Low	Unclear	High	Low	Low	Low	Low
Ivarsson (2014)⁶⁹	Low	Unclear	High	Low	Low	Low	High
Knaevelsrud (2015)⁶⁸	Low	Unclear	High	Low	High	Low	Low
Krupnick (2017)⁶⁶	Unclear	Unclear	High	Low	High	Low	High
Kuhn (2017)⁵³	Low	Unclear	High	Low	Low	Low	Low
Lewis (2017)⁵²	Low	Low	High	Low	Low	Low	High
Littleton (2016)⁷⁰	Low	Unclear	High	High	Low	Low	Low
Litz (2007)⁷¹	Unclear	Unclear	High	Low	High	Low	High
Miner (2016)⁶⁷	Unclear	Unclear	High	Low	Low	Low	Low
Spence (2011)⁵⁵	Low	Unclear	High	High	High	Low	Unclear

: Note: The assessment rating judgements in the table were made by the authors of the Cochrane review.
: Source: Lewis et al. (2018).⁴⁰

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Young C, Sinclair A, Black C, et al. Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Dec. (CADTH Optimal Use Report, No. 9.3b.) Appendix 8, Critical Appraisal of Primary Studies.
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Perspectives and Experiences Review - Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment
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Isocheles sawayai isolate X-DNA695-70 histone H3 (H3) gene, partial cds
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Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment [Internet].

Appendix 8Critical Appraisal of Primary Studies

Table 18Cochrane Risk of Bias Assessment for Included Randomized Controlled Trials

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