Literature Search Strategies

Calvin Young; Dr. Alison Sinclair; Cody Black; Elijah Herington; Elijah Herington; Dr. Maxwell Smith; Carolyn Spry; Kaitryn Campbell; Bert Dolcine

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Young C, Sinclair A, Black C, et al. Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Dec. (CADTH Optimal Use Report, No. 9.3b.)

Cover of Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment

Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment [Internet].

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Appendix 1Literature Search Strategies

Clinical Literature Search

OVERVIEW
Interface:	Ovid
Databases:	MEDLINE All (1946-June 20, 2019) Embase (1974–2019 June 20) PsycINFO (1806 to June Week 2 2019) Cochrane Central Register of Controlled Trials (May 2019) Note: Subject headings have been customized for each database. Duplicates between databases were removed in Ovid.
Date of Search:	June 21, 2019
Alerts:	Monthly search updates until project completion
Study Types:	Randomized controlled trials, controlled clinical trials
Limits:	Publication date limit: January 1, 2017-June 21, 2019 Humans
SYNTAX GUIDE
/	At the end of a phrase, searches the phrase as a subject heading
MeSH	Medical Subject Heading
.fs	Floating subheading
exp	Explode a subject heading
*	Before a word, indicates that the marked subject heading is a primary topic; or, after a word, a truncation symbol (wildcard) to retrieve plurals or varying endings
#	Truncation symbol for one character
?	Truncation symbol for one or no characters only
adj#	Requires terms to be adjacent to each other within # number of words (in any order)
.ti	Title
.ab	Abstract
.hw	Heading word; usually includes subject headings and controlled vocabulary
.kf	Author keyword heading word (MEDLINE)
.kw	Author keyword (Embase, Cochrane Cent)
.id.	Author keyword (PsycINFO)
.pt	Publication type
.mp	Mapped term
.rn	Registry number
.yr	Publication year
.jw	Journal word title
freq=#	Requires terms to occur # number of times in the specified fields
medall	Ovid database code: MEDLINE All, 1946 to present, updated daily
oemezd	Ovid database code; Embase, 1974 to present, updated daily
cctr	Ovid database code; Cochrane Central Register of Controlled Trials
psyh	Ovid database code: PsycINFO 1806 to present, updated weekly

MULTI-DATABASE STRATEGY
Line #	Search History
1	Stress Disorders, Post-Traumatic/
2	Stress Disorders, Traumatic/
3	Combat Disorders/
4	Stress Disorders, Traumatic, Acute/
5	((posttrauma* or post-trauma) adj3 (stress or disorder* or psych* or symptom*)).ti,ab,kw.
6	PTSD.ti,ab,kw.
7	(acute stress disorder* or combat disorder* or war neuros*).ti,ab,kw.
8	or/1–7
9	(android or app or apps or audio* or blog or iCBT or cCBT or i-CBT or c-CBT or CD-ROM or cell phone* or cellphone or chat or computer* or cyber* or distance* or DVD or eHealth or e-health or electronic health* or e-Portal or ePortal or etherap* or etherap* or forum* or gaming or information technolog* or instant messag* or internet* or interapy or ipad or i-pad or iphone or i-phone or ipod or i-pod or web* or WWW or smart phone or smartphone or mobile phone* or e-mail* or email* or mHealth or m-health or mobile or multi-media or multimedia or online* or on-line or personal digital assistant* or PDA or SMS or social medi* or Facebook or software or telecomm* or telehealth* or telemed* or telemonitor* or telepsychor teletherap or text messag* or texting or tape or taped or video* or YouTube or podcast or virtual* or remote).ti,ab,kw.
10	(self adj3 (care or change or guide* or help or intervention or manag* or support* or train*)).ti,ab,kw.
11	9 or 10
12	8 and 11
13	limit 12 to yr="2017 -Current"
14	posttraumatic stress disorder/
15	(PTSD or ((posttrauma* or post-trauma* or post trauma) adj3 (stress or disorder* or psych* or symptom?)) or acute stress disorder* or combat disorder* or war neuros*).ti,ab,kw.
16	(((acute or traumatic) adj stress) and (expos or psyc*)).ti,ab,kw.
17	(traumati#ed adj (victim? or survivor?)).ti,ab,kw.
18	(trauma* adj2 (event? or memor* or flashback* or nightmare?)).ti,ab,kw.
19	((trauma* or posttrauma* or post-trauma* or victim* or survivor?) and (exposure adj3 (therap* or psychotherap* or training or counsel*))).ti,ab,kw.
20	or/14–19
21	(((internet or web or online) adj3 (cognitive or behavio)) or iCBT or i-CBT or ePsych or e-Psych* or cCBT or cCBT).ti,ab,kw.
22	(android or app or apps or blog* or CD-ROMor cell phone or cellphone or chat room or computer* or cyber* or digital or technology based or DVD or eHealth or e-health or electronic health or e-mail* or email* or e-Portal or ePortal or eTherap* or e-therap* or forum* or gaming or information technolog* or instant messag* or messaging or internet* or ipad or i-pad or iphone or i-phone or ipod or i-pod or podcast or smart phone or smartphone or social network* site* or social networking or mHealth or m-health or mobile or multi-media or multimedia or online* or on-line or personal digital assistant or PDA or SMS or social medi* or software or telecomm* or telehealth* or telemed* or telemonitor* or telepsych* or teletherap* or tele-health* or tele-med* or tele-monitor* or tele-psych* or tele-therap* or text messag* or texting or virtual* or web* or WWW).ti,ab,kw,hw.
23	internet/
24	blogging/ or e-mail/ or social media/ or text messaging/ or videoconferencing/ or webcast/ or wireless communication/
25	telecommunication/ or teleconference/
26	telemedicine/ or telehealth/ or telepsychiatry/ or teletherapy/
27	mobile phone/ or smartphone/
28	mobile application.hw.
29	*technology/
30	computer program/ or digital computer/ or personal computer/ or computer assisted therapy/
31	*computer/
32	(telecomm* or tele-comm*).ti,ab,kw.
33	(eLearning or blended learning).ti,ab,kw.
34	(videoconferenc* or video conferenc*).ti,ab,kw.
35	(synchronous or asynchronous or (electronic adj2 deliver*)).ti,ab,kw.
36	or/22–35
37	(behavio* or cognitive).ti. or (psychotherap* or psychological therap* or cognitive behavio* or ((cognitive or behavio) adj2 (activat or component? or defusion or modif* or restructur* or technique* or intervention or treatment* or therap* or train)) or ((acceptance or commitment) adj3 therap) or rational emotive or RET or problem sol* or PST or problem focus* or solution focus* or trauma focus* or psychoeducat* or psycho-educat* or psychodrama or psycho-drama* or mindfulness* or third wave or self-control or (self* adj3 (control or efficacy)) or stress manage* or exposure or reality therap* or (anxiety adj3 (management or therap* or train)) or relaxation or guided imagery or present cent or person cent* or person* construct* or therapeutic process* or schema? or schemata or (thought* adj3 suppress*) or rumination).mp.
38	36 and 37
39	randomized controlled trial/
40	randomization.de.
41	controlled clinical trial/ and (Disease Management or Drug Therapy or Prevention or Rehabilitation or Therapy).fs.
42	*clinical trial/
43	placebo.de.
44	placebo.ti,ab.
45	trial.ti.
46	(randomi#ed or randomi#ation or randomi#ing).ti,ab,kw.
47	(RCT or “at random” or (random* adj3 (administ* or allocat* or assign* or class* or control* or determine* or divide* or division or distribut* or expose* or fashion or number* or place* or recruit* or subsitut* or treat*))).ti,ab,kw.
48	((singl$ or doubl$ or trebl$ or tripl$) adj3 (blind$ or mask$ or dummy)).mp.
49	(control* and (trial or study or group) and (placebo or waitlist* or wait* list* or ((treatment or care) adj2 usual))).ti,ab,kw,hw.
50	or/39–49
51	((animal or nonhuman) not (human and (animal or nonhuman))).de.
52	50 not 51
53	20 and (21 or 38) and 52
54	(2017* or 2018* or 2019*).yr,dp,dt,ed,ep.
55	53 and 54
56	"Trauma and Stressor Related Disorders"/ or stress disorders, traumatic/ or combat disorders/ or psychological trauma/ or stress disorders, post-traumatic/ or stress disorders, traumatic, acute/
57	(PTSD or ((posttrauma* or post-trauma* or post trauma) adj3 (stress or disorder* or psych* or symptom?)) or acute stress disorder* or combat disorder* or war neuros*).ti,ab,kf.
58	(((acute or traumatic) adj stress) and (expos or psyc*)).ti,ab,kf.
59	(traumati#ed adj (victim? or survivor?)).ti,ab,kf.
60	(trauma* adj2 (event? or memor* or flashback* or nightmare?)).ti,ab,kf.
61	((trauma* or posttrauma* or post-trauma* or victim* or survivor?) and (exposure adj3 (therap* or psychotherap* or training or counsel*))).ti,ab,kf.
62	or/56–61
63	(((internet or web or online) adj3 (cognitive or behavio)) or iCBT or i-CBT or ePsych or e-Psych* or cCBT or c-CBT).ti,ab,kf.
64	(android or app or apps or blog* or CD-ROMor cell phone or cellphone or chat room or computer* or cyber* or digital or technology based or DVD or eHealth or e-health or electronic health or e-mail* or email* or e-Portal or ePortal or eTherap* or e-therap* or forum* or gaming or information technolog* or instant messag* or messaging or internet* or ipad or i-pad or iphone or i-phone or ipod or i-pod or podcast or smart phone or smartphone or social network* site* or social networking or mHealth or m-health or mobile or multi-media or multimedia or online* or on-line or personal digital assistant or PDA or SMS or social medi* or software or telecomm* or telehealth* or telemed* or telemonitor* or telepsych* or teletherap* or tele-health* or tele-med* or tele-monitor* or tele-psych* or tele-therap* or text messag* or texting or virtual* or web* or WWW).ti,ab,kf,hw.
65	computer communication networks/ or internet/ or blogging/ or social media/
66	cell phones/ or smartphone/ or text messaging/ or videoconferencing/ or webcasts as topic/ or wireless technology/
67	(telecomm* or tele-comm*).ti,ab,kf.
68	Telemedicine/
69	(eLearning or blended learning).ti,kf.
70	(videoconferenc* or video conferenc*).ti,kf.
71	(synchronous or asynchronous or (electronic adj2 deliver*)).ti,kf.
72	or/64–71
73	(behavio* or cognitive).ti. or (psychotherap* or psychological therap* or cognitive behavio* or ((cognitive or behavio) adj2 (activat or component? or defusion or modif* or restructur* or technique* or intervention or treatment* or therap* or train)) or ((acceptance or commitment) adj3 therap) or rational emotive or RET or problem sol* or PST or problem focus* or solution focus* or trauma focus* or psychoeducat* or psycho-educat* or psychodrama or psycho-drama* or mindfulness* or third wave or self-control or (self* adj3 (control or efficacy)) or stress manage* or exposure or reality therap* or (anxiety adj3 (management or therap* or train)) or relaxation or guided imagery or present cent or person cent* or person* construct* or therapeutic process* or schema? or schemata or (thought* adj3 suppress*) or rumination).mp.
74	72 and 73
75	controlled clinical trial.pt.
76	randomized controlled trial.pt.
77	(randomi#ed or randomi#ation or randomi#ing).ti,ab,kf.
78	(RCT or at random or (random* adj3 (assign* or allocat* or control* or crossover or cross-over or design* or divide* or division or number))).ti,ab,kf.
79	placebo*.ab,ti,kf.
80	trial.ab,ti,kf.
81	groups.ab.
82	(control* and (trial or study or group) and (placebo or waitlist or wait* list* or ((treatment or care) adj2 usual))).ti,ab,kf,hw.
83	double-blind method/ or random allocation/ or single-blind method/
84	((single or double or triple or treble) adj2 (blind* or mask* or dummy)).ti,ab,kf.
85	or/75–84
86	exp animals/ not humans.sh.
87	85 not 86
88	62 and (63 or 74) and 87
89	(2017* or 2018* or 2019*).yr,dp,dt,ed,ep.
90	88 and 89
91	posttraumatic stress disorder/ or complex ptsd/ or acute stress disorder/ or combat experience/ or “debriefing (psychological)”/ or emotional trauma/ or post-traumatic stress/ or exp stress reactions/ or traumatic neurosis/
92	exp DISASTERS/
93	(PTSD or ((posttrauma* or post-trauma* or post trauma) adj3 (stress or disorder* or psych* or symptom?)) or acute stress disorder* or combat disorder* or war neuros*).ti,ab,id.
94	(((acute or traumatic) adj stress) and (expos or psyc*)).ti,ab,id.
95	(trauma* adj2 (event? or memor* or flashback* or nightmare?)).ti,ab,id.
96	((trauma* or posttrauma* or post-trauma* or victim* or survivor?) and (exposure adj3 (therap* or psychotherap* or training or counsel*))).ti,ab,id,hw.
97	(traumati#ed adj (victim? or survivor?)).ti,ab,id.
98	or/91–97
99	(((internet or web or online) adj3 (cognitive or behavio)) or iCBT or i-CBT or ePsych or e-Psych* or c-CBT or cCBT).ti,ab,kf.
100	(android or app or apps or blog* or CD-ROM or cell phone or cellphone or chat room or computer* or cyber* or digital or technology based or DVD or eHealth or e-health or electronic health or e-mail* or email* or e-Portal or ePortal or eTherap* or etherap* or forum* or gaming or information technolog* or instant messag* or messaging or internet* or ipad or i-pad or iphone or iphone or ipod or i-pod or podcast or smart phone or smartphone or social network* site* or social networking or mHealth or m-health or mobile or multi-media or multimedia or online* or on-line or personal digital assistant or PDA or SMS or social medi* or software or telecomm* or telehealth* or telemed* or telemonitor* or telepsych* or teletherap* or tele-health* or tele-med* or tele-monitor* or tele-psych* or tele-therap* or text messag* or texting or virtual* or web* or WWW).ti,ab,id,hw.
101	(telecomm* or tele-comm*).ti,ab,id.
102	(eLearning or blended learning).ti,ab,id.
103	(videoconferenc* or video conferenc*).ti,ab,id.
104	(synchronous or asynchronous or (electronic adj2 deliver*)).ti,ab,id.
105	internet/ or websites/
106	mobile devices/ or cellular phones/
107	social media/ or online social networks/ or blog/ or online community/ or text messaging/
108	electronic communication/ or exp computer mediated communication/ or electronic learning/
109	online therapy/ or telemedicine/
110	telecommunications media/
111	teleconferencing/
112	technology/ or information technology/ or exp computer applications/ or computer software/
113	computers/ or computer games/ or digital computers/ or microcomputers/
114	or/100–113
115	(behavio* or cognitive).ti. or (psychotherap* or psychological therap* or cognitive behavio* or ((cognitive or behavio) adj2 (activat or component? or defusion or modif* or restructur* or technique* or intervention or treatment* or therap* or train)) or ((acceptance or commitment) adj3 therap) or rational emotive or RET or problem sol* or PST or problem focus* or solution focus* or trauma focus* or psychoeducat* or psycho-educat* or psychodrama or psycho-drama* or mindfulness* or third wave or self-control or (self* adj3 (control or efficacy)) or stress manage* or exposure or reality therap* or (anxiety adj3 (management or therap* or train)) or relaxation or guided imagery or present cent or person cent* or person* construct* or therapeutic process* or schema? or schemata or (thought* adj3 suppress*) or rumination).ti,ab,id,hw.
116	(self adj (care or change or guide* or help or intervention or manag* or support* or train*)).ti,id.
117	114 and (115 or 116)
118	clinical trials.sh.
119	(randomi#ed or randomi#ation or randomi#ing).ti,ab,id.
120	(RCT or at random or (random* adj3 (assign* or allocat* or control* or crossover or cross-over or design* or divide* or division or number))).ti,ab,id.
121	(control* and (trial or study or group) and (placebo or waitlist* or wait* list* or ((treatment or care) adj2 usual))).ti,ab,id,hw.
122	((single or double or triple or treble) adj2 (blind* or mask* or dummy)).ti,ab,id.
123	trial.ti.
124	placebo.ti,ab,id,hw.
125	treatment outcome.md.
126	treatment effectiveness evaluation.sh.
127	mental health program evaluation.sh.
128	or/118–127
129	98 and (99 or 117) and 128
130	(2017* or 2018* or 2019*).yr,an.
131	129 and 130
132	13 use cctr
133	55 use oemezd
134	90 use medal
135	131 use psyh
136	132 or 133 or 134 or 135
137	remove duplicates from 136

CLINICAL TRIAL REGISTRIES

ClinicalTrials.gov

Produced by the U.S. National Library of Medicine. Targeted search used to capture registered clinical trials.

Search: internet | post traumatic stress disorder | CBT

WHO ICTRP

International Clinical Trials Registry Platform, produced by the World Health Organization. Targeted search used to capture registered clinical trials.

Search: (internet or web or app or apps or mobile or self) AND ptsd AND CBT

Patients’ Preferences and Experiences Literature Search #1 (iCBT + PTSD)

OVERVIEW
Interface:	Ovid
Databases:	MEDLINE All (1946-May 21, 2019) PsycINFO (1806-May week 3, 2019) Note: Subject headings have been customized for each database. Duplicates between databases were removed in Ovid for the Ovid searches.
Date of Search:	May 23, 2019
Alerts:	Monthly search updates until project completion
Study Types:	Qualitative studies
Limits:	Publication date limit: January 1, 2008 – May 23, 2019 Language limit: English- and French-language
SYNTAX GUIDE
/	At the end of a phrase, searches the phrase as a subject heading
.fs	Floating subheading exp Explode a subject heading
*	Before a word, indicates that the marked subject heading is a primary topic; or, after a word, a truncation symbol (wildcard) to retrieve plurals or varying endings
#	Truncation symbol for one character
?	Truncation symbol for one or no characters only
adj#	Requires terms to be adjacent to each other within # number of words (in any order)
.ti	Title
.ab	Abstract
.hw	Heading word; usually includes subject headings and controlled vocabulary
.kf	Author keyword heading word (MEDLINE)
.id	Author keyword (PsycINFO)
.pt	Publication type
.mp	Mapped term
.yr	Publication year
.dp	Date of publication
.dt	Create date
.ed	Entry date
.ep	Electronic date of publication
medall	Ovid database code: MEDLINE All, 1946 to present, updated daily
psyh	Ovid database code: PsycINFO, 1806 to present, updated weekly

MULTI-DATABASE STRATEGY
Line #	Search History
1	Cognitive Behavioral Therapy/ or “Acceptance and Commitment Therapy”/ or Psycho-therapy/ or Desensitization, Psychologic/ or Implosive Therapy/
2	(((cognitive or behavio* or facilitate* or guided or saturat* or unguided) adj2 (therap* or psychotherap* or psychotherap)) or cognitive behavio or cognition therap* or CBT*).ti,ab,kf,kw,id.
3	(self-manag* or selfmanag* or self-help* or selfhelp*).ti,ab,kf,kw,id.
4	((psycholog* adj3 desensiti) or imaginal flooding or (imager* adj3 exposure*)).ti,ab,kf,kw,id.
5	((exposure or flooding* or implosive or saturation) adj3 therap*).ti,ab,kf,kw,id.
6	or/1–5
7	Internet/ or exp Computers/ or Therapy, Computer-Assisted/ or Computer-Assisted Instruction/ or Distance Counseling/ or Cell Phone/ or Mobile Applications/ or Remote Consultation/ or exp Telemedicine/ or exp Videoconferencing/
8	(internet* or Beacon or app or apps or computer* or cyber-therap* or cybertherap* or e mail* or email* or electronic mail* or “Information and communication technology” or “Information and communication technologies” or emedicine or e medicine or ehealth* or e health* or emental health* or e mental health* or etherap* or e therap* or epsychiatr* or e psychiatr* or epsychol* or e psychol* or media deliver* or mobile* or online* or smartphone* or smart phone* or telemedicine or tele medicine or telehealth* or tele health* or telemental health* or tele mental health* or telecare or tele care or teletherap* or tele therap* or telepsychiatr* or tele psychiatr* or telepsychol* or tele psychol* or telepsychotherap* or tele-psycho-therap* or telepsychotherap* or tele-psychotherap* or tele-coach* or telecoach* or virtual or virtualist? or webbased or web based or web deliver* or webdeliver*).ti,ab,kf,kw,id.
9	or/7–8
10	exp Stress Disorders, Traumatic/
11	(PTSD or posttrauma* or post-trauma* or panic disorder* or panic attack* or shell shock or war neurosis or war neuroses or acute stress disorder* or operational stress or past trauma* or PTD or complex trauma* or traumatic stress or moral injur* or trauma-base* or trauma-focus*).ti,ab,kf,kw,id.
12	(combat* adj3 (neuroses* or neurosis* or stress* or fatigue* or disorder*)).ti,ab,kf,kw,id.
13	or/10–12
14	(c-CBT* or iCBT* or eCBT*).ti,ab,kf,kw,id.
15	((computer* or cyber* or digital* or technolog* or web) adj6 (CBT or coach or deliver* or intervention* or psychiatr* or psycho-dynamic or psychodynamic or psycholog* or psycho-therap* or psychotherap* or therap* or technique* or training or treatment*)).ti,ab,kf,kw,id.
16	(MoodGym or Big White Wall or Beating the Blues or Fear Fighter or E compass or Ecompass or Deprexis or Moodkit or “Living Life to the Full” or Woebot).ti,ab,kf,kw,id.
17	(e-mental health or emental health).ti,ab,kf,kw,id.
18	(ACT Coach or ((“Anger and Irritability Management Skills” or AIMS) adj5 app) or Behavior Tracker Pro or Breathe2Relax or CBT-I Coach or CPT Coach or (cognitive processing therap adj2 coach*) or Dream EZ or Life Armor or Mood Coach or Moving Forward or PE Coach or PTSD Coach or “T2 Mood Tracker” or Tactical Breather or VetChange or Interapy).ti,ab,kf,kw,id.
19	or/14–18
20	6 and 9 and 13
21	13 and 19
22	20 or 21
23	22 use medall
24	exp Cognitive Behavior Therapy/ or Cognitive Therapy/
25	(((cognitive or behavio* or facilitate* or guided or saturat* or unguided) adj2 (therap* or psychotherap* or psycho-therap)) or cognitive behavio or cognition therap* or CBT*).ti,ab,kf,kw,id.
26	(self-manag* or selfmanag* or self-help* or selfhelp*).ti,ab,kf,kw,id.
27	((psycholog* adj3 desensiti) or imaginal flooding or (imager* adj3 exposure*)).ti,ab,kf,kw,id.
28	((exposure or flooding* or implosive or saturation) adj3 therap*).ti,ab,kf,kw,id.
29	or/24–28
30	Telemedicine/ or Computer-Assisted therapy/ or Computer-Assisted Instruction/ or Internet/ or exp Mobile Devices/ or Online Therapy/
31	(internet* or Beacon or app or apps or computer* or cyber-therap* or cybertherap* or e mail* or email* or electronic mail* or “Information and communication technology” or “Information and communication technologies” or emedicine or e medicine or ehealth* or e health* or emental health* or e mental health* or etherap* or e therap* or epsychiatr* or e psychiatr* or epsychol* or e psychol* or media deliver* or mobile* or online* or smartphone* or smart phone* or telemedicine or tele medicine or telehealth* or tele health* or telemental health* or tele mental health* or telecare or tele care or teletherap* or tele therap* or telepsychiatr* or tele psychiatr* or telepsychol* or tele psychol* or telepsycho-therap* or tele-psycho-therap* or telepsychotherap* or tele-psychotherap* or tele-coach* or telecoach* or virtual or virtualist? or webbased or web based or web deliver* or webdeliver*).ti,ab,kf,kw,id.
32	or/30–31
33	exp Posttraumatic Stress Disorder/ or Combat Experience/ or Emotional Trauma/ or Post-Traumatic Stress/ or Traumatic Neurosis/
34	(PTSD or posttrauma* or post-trauma* or panic disorder* or panic attack* or shell shock or war neurosis or war neuroses or acute stress disorder* or operational stress or past trauma* or PTD or complex trauma* or traumatic stress or moral injur* or trauma-base* or trauma-focus*).ti,ab,kf,kw,id.
35	(combat* adj3 (neuroses* or neurosis* or stress* or fatigue* or disorder*)).ti,ab,kf,kw,id.
36	or/33–35
37	(cCBT* or iCBT* or eCBT*).ti,ab,kf,kw,id.
38	((computer* or cyber* or digital* or technolog* or web) adj6 (CBT or coach or deliver* or intervention* or psychiatr* or psycho-dynamic or psychodynamic or psycholog* or psycho-therap* or psychotherap* or therap* or technique* or training or treatment*)).ti,ab,kf,kw,id.
39	(MoodGym or Big White Wall or Beating the Blues or Fear Fighter or E compass or Ecompass or Deprexis or Moodkit or “Living Life to the Full” or Woebot).ti,ab,kf,kw,id.
40	(e-mental health or emental health).ti,ab,kf,kw,id.
41	(ACT Coach or ((“Anger and Irritability Management Skills” or AIMS) adj5 app) or Behavior Tracker Pro or Breathe2Relax or CBT-I Coach or CPT Coach or (cognitive processing therap adj2 coach*) or Dream EZ or Life Armor or Mood Coach or Moving Forward or PE Coach or PTSD Coach or “T2 Mood Tracker” or Tactical Breather or VetChange or Interapy).ti,ab,kf,kw,id.
42	or/37–41
43	29 and 32 and 36
44	36 and 42
45	43 or 44
46	45 use psyh
47	23 or 46
48	47 and (english or french).la.
49	limit 48 to yr="2008 -Current"
50	exp Empirical Research/ or Interviews as Topic/ or Personal Narratives/ or Focus Groups/ or exp Narration/ or Nursing Methodology Research/ or Narrative Medicine/
51	Interview/
52	Qualitative Research/ or Grounded Theory/ or Narratives/ or Storytelling/ or exp Life Experiences/ or exp Interviews/
53	interview*.ti,ab,kf,id.
54	qualitative*.ti,ab,kf,jw,id.
55	(theme* or thematic).ti,ab,kf,id.
56	ethnological research.ti,ab,kf,id.
57	ethnograph*.ti,ab,kf,id.
58	ethnomedicine.ti,ab,kf,id.
59	ethnonursing.ti,ab,kf,id.
60	phenomenol*.ti,ab,kf,id.
61	(grounded adj (theor* or study or studies or research or analys?s)).ti,ab,kf,id.
62	(life stor* or women* stor*).ti,ab,kf,id.
63	(emic or etic or hermeneutic* or heuristic* or semiotic*).ti,ab,kf,id.
64	(data adj1 saturat$).ti,ab,kf,id.
65	participant observ*.ti,ab,kf,id.
66	(social construct* or postmodern* or post-structural* or post-structural* or poststructural* or post modern* or postmodern* or feminis*).ti,ab,kf,id.
67	(action research or cooperative inquir* or co operative inquir* or co-operative inquir*).ti,ab,kf,id.
68	(humanistic or existential or experiential or paradigm*).ti,ab,kf,id.
69	(field adj (study or studies or research or work)).ti,ab,kf,id.
70	(human science or social science).ti,ab,kf,id.
71	biographical method.ti,ab,kf,id.
72	theoretical sampl*.ti,ab,kf,id.
73	((purpos* adj4 sampl) or (focus adj group)).ti,ab,kf,id.
74	(open-ended or narrative* or textual or texts or semi-structured).ti,ab,kf,id.
75	(life world* or life-world* or conversation analys?s or personal experience* or theoretical saturation).ti,ab,kf,id.
76	((lived or life) adj experience*).ti,ab,kf,id.
77	cluster sampl*.ti,ab,kf,id.
78	observational method*.ti,ab,kf,id.
79	content analysis.ti,ab,kf,id.
80	(constant adj (comparative or comparison)).ti,ab,kf,id.
81	((discourse* or discurs*) adj3 analys?s).ti,ab,kf,id.
82	(heidegger* or colaizzi* or spiegelberg* or merleau* or husserl* or foucault* or ricoeur or glaser*).ti,ab,kf,id.
83	(van adj manen*).ti,ab,kf,id.
84	(van adj kaam*).ti,ab,kf,id.
85	(corbin* adj2 strauss*).ti,ab,kf,id.
86	or/50–85
87	49 and 86
88	remove duplicates from 87

OTHER DATABASES
PubMed	Searched to capture records not found in MEDLINE. Same MeSH, keywords, limits, and study types used as per MEDLINE search, with appropriate syntax used.
CINAHL	Same MeSH, keywords, and limits used as per MEDLINE search, excluding study types and human restrictions. Syntax adjusted for EBSCO platform, including the addition of CINAHL headings.

Patients’ Preferences and Experiences Literature Search #2 (CBT + PTSD)

OVERVIEW
Interface:	Ovid
Databases:	MEDLINE All (1946-July 15, 2019) PsycINFO (1806-July week 2, 2019) Note: Subject headings have been customized for each database. Duplicates between databases were removed in Ovid for the Ovid searches.
Date of Search:	July 16, 2019
Alerts:	Monthly search updates until project completion
Study Types:	Qualitative studies
Limits:	Publication date limit: January 1, 2014 – July 16, 2019 Language limit: English- and French-language
SYNTAX GUIDE
/	At the end of a phrase, searches the phrase as a subject heading
.fs	Floating subheading exp Explode a subject heading
*	Before a word, indicates that the marked subject heading is a primary topic; or, after a word, a truncation symbol (wildcard) to retrieve plurals or varying endings
#	Truncation symbol for one character
?	Truncation symbol for one or no characters only
adj#	Requires terms to be adjacent to each other within # number of words (in any order)
.ti	Title
.ab	Abstract
.hw	Heading word; usually includes subject headings and controlled vocabulary
.kf	Author keyword heading word (MEDLINE)
.id	Author keyword (PsycINFO)
.pt	Publication type
.mp	Mapped term
.yr	Publication year
.dp	Date of publication
.dt	Create date
.ed	Entry date
.ep	Electronic date of publication medall Ovid database code: MEDLINE All, 1946 to present, updated daily
psyh	Ovid database code: PsycINFO, 1806 to present, updated weekly

MULTI-DATABASE STRATEGY
Line #	Search History
1	Cognitive Behavioral Therapy/ or “Acceptance and Commitment Therapy”/ or Psychotherapy/ or Desensitization, Psychologic/ or Implosive Therapy/
2	(((cognitive or behavio* or facilitate* or guided or saturat* or unguided) adj2 (therap* or psychotherap* or psycho-therap)) or cognitive behavio or cognition therap* or CBT*).ti,ab,kf,kw,id.
3	(self-manag* or selfmanag* or self-help* or selfhelp*).ti,ab,kf,kw,id.
4	((psycholog* adj3 desensiti) or imaginal flooding or (imager* adj3 exposure*)).ti,ab,kf,kw,id.
5	((exposure or flooding* or implosive or saturation) adj3 therap*).ti,ab,kf,kw,id.
6	or/1–5
7	exp Stress Disorders, Traumatic/
8	(PTSD or posttrauma* or post-trauma* or panic disorder* or panic attack* or shell shock or war neurosis or war neuroses or acute stress disorder* or operational stress or past trauma* or PTD or complex trauma* or traumatic stress or moral injur* or trauma-base* or trauma-focus*).ti,ab,kf,kw,id.
9	(combat* adj3 (neuroses* or neurosis* or stress* or fatigue* or disorder*)).ti,ab,kf,kw,id.
10	or/7–9
11	6 and 10
12	11 use medall
13	exp Cognitive Behavior Therapy/ or Cognitive Therapy/
14	(((cognitive or behavio* or facilitate* or guided or saturat* or unguided) adj2 (therap* or psychotherap* or psycho-therap)) or cognitive behavio or cognition therap* or CBT*).ti,ab,kf,kw,id.
15	(self-manag* or selfmanag* or self-help* or selfhelp*).ti,ab,kf,kw,id.
16	((psycholog* adj3 desensiti) or imaginal flooding or (imager* adj3 exposure*)).ti,ab,kf,kw,id.
17	((exposure or flooding* or implosive or saturation) adj3 therap*).ti,ab,kf,kw,id.
18	or/13–17
19	exp Posttraumatic Stress Disorder/ or Combat Experience/ or Emotional Trauma/ or Post-Traumatic Stress/ or Traumatic Neurosis/
20	(PTSD or posttrauma* or post-trauma* or panic disorder* or panic attack* or shell shock or war neurosis or war neuroses or acute stress disorder* or operational stress or past trauma* or PTD or complex trauma* or traumatic stress or moral injur* or trauma-base* or trauma-focus*).ti,ab,kf,kw,id.
21	(combat* adj3 (neuroses* or neurosis* or stress* or fatigue* or disorder*)).ti,ab,kf,kw,id.
22	or/19–21
23	18 and 22
24	23 use psyh
25	12 or 24
26	25 and (english or french).la.
27	limit 26 to yr="2014 -Current"
28	exp Empirical Research/ or Interview/ or Interviews as Topic/ or Personal Narratives/ or Focus Groups/ or exp Narration/ or Nursing Methodology Research/ or Narrative Medicine/
29	Interview/
30	Qualitative Research/ or Grounded Theory/ or Narratives/ or Storytelling/ or exp Life Experiences/ or exp Interviews/
31	interview*.ti,ab,kf,id.
32	qualitative*.ti,ab,kf,jw,id.
33	(theme* or thematic).ti,ab,kf,id.
34	ethnological research.ti,ab,kf,id.
35	ethnograph*.ti,ab,kf,id.
36	ethnomedicine.ti,ab,kf,id.
37	ethnonursing.ti,ab,kf,id.
38	phenomenol*.ti,ab,kf,id.
39	(grounded adj (theor* or study or studies or research or analys?s)).ti,ab,kf,id.
40	(life stor* or women* stor*).ti,ab,kf,id.
41	(emic or etic or hermeneutic* or heuristic* or semiotic*).ti,ab,kf,id.
42	(data adj1 saturat$).ti,ab,kf,id.
43	participant observ*.ti,ab,kf,id.
44	(social construct* or postmodern* or post-structural* or post structural* or poststructural* or post modern* or post-modern* or feminis*).ti,ab,kf,id.
45	(action research or cooperative inquir* or co operative inquir* or co-operative inquir*).ti,ab,kf,id.
46	(humanistic or existential or experiential or paradigm*).ti,ab,kf,id.
47	(field adj (study or studies or research or work)).ti,ab,kf,id.
48	(human science or social science).ti,ab,kf,id.
49	biographical method.ti,ab,kf,id.
50	theoretical sampl*.ti,ab,kf,id.
51	((purpos* adj4 sampl) or (focus adj group)).ti,ab,kf,id.
52	(open-ended or narrative* or textual or texts or semi-structured).ti,ab,kf,id.
53	(life world* or life-world* or conversation analys?s or personal experience* or theoretical saturation).ti,ab,kf,id.
54	((lived or life) adj experience*).ti,ab,kf,id.
55	cluster sampl*.ti,ab,kf,id.
56	observational method*.ti,ab,kf,id.
57	content analysis.ti,ab,kf,id.
58	(constant adj (comparative or comparison)).ti,ab,kf,id.
59	((discourse* or discurs*) adj3 analys?s).ti,ab,kf,id.
60	(heidegger* or colaizzi* or spiegelberg* or merleau* or husserl* or foucault* or ricoeur or glaser*).ti,ab,kf,id.
61	(van adj manen*).ti,ab,kf,id.
62	(van adj kaam*).ti,ab,kf,id.
63	(corbin* adj2 strauss*).ti,ab,kf,id.
64	or/28–63
65	27 and 64
66	remove duplicates from 65

OTHER DATABASES
PubMed	Searched to capture records not found in MEDLINE. Same MeSH, keywords, limits, and study types used as per MEDLINE search, with appropriate syntax used.
CINAHL	Same MeSH, keywords, and limits used as per MEDLINE search, excluding study types and human restrictions. Syntax adjusted for EBSCO platform, including the addition of CINAHL headings.

Grey Literature

Dates for Search:	June 10, 2019 - July 4, 2019
Keywords:	Internet, Cognitive Behavioural Therapy, PTSD
Limits:	Publication years: January 1, 2008 – present

Relevant websites from the following sections of the CADTH grey literature checklist, Grey Matters: A Practical Tool For Searching Health-Related Grey Literature (https://www.cadth.ca/grey-matters),⁴³ were searched:

health technology assessment agencies
health economics
clinical practice guidelines
clinical trial registries
databases (free)
Internet search
open access journals.

The copyright and other intellectual property rights in this document are owned by CADTH and its licensors. These rights are protected by the Canadian Copyright Act and other national and international laws and agreements. Users are permitted to make copies of this document for non-commercial purposes only, provided it is not modified when reproduced and appropriate credit is given to CADTH and its licensors.

Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

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Young C, Sinclair A, Black C, et al. Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Dec. (CADTH Optimal Use Report, No. 9.3b.) Appendix 1, Literature Search Strategies.
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Literature Search Strategies - Internet-Delivered Cognitive Behavioural Therapy ...
Literature Search Strategies - Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment
List of Excluded Studies and Reasons for Exclusion — Clinical Review - Internet-...
List of Excluded Studies and Reasons for Exclusion — Clinical Review - Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment
Study Selection Flow Diagram — Clinical Review - Internet-Delivered Cognitive Be...
Study Selection Flow Diagram — Clinical Review - Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment
Isocheles sawayai isolate X-DNA747-107 histone H3 (H3) gene, partial cds
Isocheles sawayai isolate X-DNA747-107 histone H3 (H3) gene, partial cds
gi|1699474933|gb|MH211649.1|
Nucleotide
Isocheles pilosus isolate X-DNA710-89 histone H3 (H3) gene, partial cds
Isocheles pilosus isolate X-DNA710-89 histone H3 (H3) gene, partial cds
gi|1699474929|gb|MH211647.1|
Nucleotide

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Internet-Delivered Cognitive Behavioural Therapy for Post-Traumatic Stress Disorder: A Health Technology Assessment [Internet].

Appendix 1Literature Search Strategies

Clinical Literature Search

Patients’ Preferences and Experiences Literature Search #1 (iCBT + PTSD)

Patients’ Preferences and Experiences Literature Search #2 (CBT + PTSD)

Grey Literature

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