CLINICAL FULL-TEXT SCREENING CHECKLIST

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Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment — Project Protocol [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2016 Sep 29. (CADTH Optimal Use Report, No. 6.3a.)

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Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment — Project Protocol [Internet].

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APPENDIX 2CLINICAL FULL-TEXT SCREENING CHECKLIST

Reviewer: ________________________________
Date: ________________________

Ref ID:
Author:
Publication Year:

Did the study include:	Yes (Include)	Unclear (Include or exclude)^a	No (Exclude)

1. Adults (i.e., aged ≥ 18 years), being tested for PE (as per Table 1)	▢	▢	▢

2. The interventions of interest: Risk Stratification Strategies • Wells or Geneva rules • PERC • D-Dimer • Biochemical or imaging studies Imaging • CT-based studies • MRI-based studies • V/Q-based studies • PET-based studies • Thoracic ultrasound	▢	▢	▢

3. The comparators of interest: Risk Stratification Strategies • Composite reference standard • Any alternative clinical decision rule or modified/tailored tool ± PERC ± D- dimer ± biochemical or imaging-based risk stratification • No clinical rule (Gestalt) Imaging • Composite reference standard • CT-based studies • MRI-based studies • V/Q-based studies • PET-based studies • Thoracic ultrasound	▢	▢	▢

4. The outcomes of interest: • DTA • Clinical utility • Direct patient harms	▢	▢	▢

5. The study designs of interest: • SR • MA • HTA • RCT • NRS • CS	▢	▢	▢

Decision to include the study:^b	Yes ▢		No ▢

Reason(s) for exclusion:	Inappropriate study population No intervention of interest No or inappropriate comparator No relevant outcomes Irrelevant study design Study description only Other:______________

: CS = case series; CT = computed tomography; DTA = diagnostic test accuracy; HTA = health technology assessment; MA = meta-analysis; MRI = magnetic resonance imaging; NRS = non-randomized study; PE = pulmonary embolism; PERC = Pulmonary Embolism Rule-Out Criteria; PET = positron emission tomography; RCT = randomized controlled trial; SR = systematic review; V/Q = ventilation-perfusion.
a: This will be discussed with a second reviewer.
b: If all items above are answered “yes” or “unclear,” then the study will be included.
: Did the study report any data relevant to another research question (RQ)? ▢ Yes: RQ# __________ ▢ No

The copyright and other intellectual property rights in this document are owned by CADTH and its licensors. These rights are protected by the Canadian Copyright Act and other national and international laws and agreements. Users are permitted to make copies of this document for non-commercial purposes only, provided it is not modified when reproduced and appropriate credit is given to CADTH and its licensors.

Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial- NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

Bookshelf ID: NBK395898

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Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment — Project Protocol [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2016 Sep 29. (CADTH Optimal Use Report, No. 6.3a.) APPENDIX 2, CLINICAL FULL-TEXT SCREENING CHECKLIST.
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APPENDIX 2CLINICAL FULL-TEXT SCREENING CHECKLIST

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