As a follow-up to the overview of reviews conducted for Research Questions 1a and 1b in the main health technology assessment (HTA) protocol, and to address gaps within the published systematic review (SR) literature, an SR of relevant published primary studies on the clinical effectiveness, comparative clinical effectiveness, and safety of interventions for the treatment of obstructive sleep apnea (OSA) in adults will be conducted. Specifically, this SR will focus on addressing Research Questions 1a and 1b, in relation to certain combinations of interventions, comparators, and outcomes that are missing in the overview of reviews, as listed in Table 1.

Contents

• CLINICAL REVIEW
  • Study Design
  • Literature Search
  • Selection Criteria
  • Exclusion Criteria
  • Screening and Selecting Studies for Inclusion
  • Data Extraction
  • Risk of Bias Assessments
  • Summary of Evidence
• REFERENCES
• APPENDIX 1. LITERATURE SEARCH STRATEGY
• APPENDIX 2. FULL-TEXT SCREENING CHECKLIST
• APPENDIX 3. DATA EXTRACTION FORM

Suggested citation:

Addendum to Interventions for the treatment of obstructive sleep apnea in adults: a health technology assessment — project protocol. Ottawa: CADTH; 2016 June. (CADTH optimal use report; vol.6, no.1a).

This report is prepared by the Canadian Agency for Drugs and Technologies in Health (CADTH). This report contains a comprehensive review of existing public literature, studies, materials, and other information and documentation (collectively the “source documentation”) available to CADTH at the time it was prepared, and it was guided by expert input and advice throughout its preparation.

The information in this report is intended to help health care decision-makers, patients, health care professionals, health systems leaders, and policy-makers make well-informed decisions and thereby improve the quality of health care services. The information in this report should not be used as a substitute for the application of clinical judgment in respect to the care of a particular patient or other professional judgment in any decision-making process, nor is it intended to replace professional medical advice. While CADTH has taken care in the preparation of this report to ensure that its contents are accurate, complete, and up-to-date, CADTH does not make any guarantee to that effect. CADTH is not responsible for any errors or omissions or injury, loss, or damage arising from or as a result of the use (or misuse) of any information contained in or implied by the information in this report.

CADTH takes sole responsibility for the final form and content of this report. The statements, conclusions, and views expressed herein do not necessarily represent the view of Health Canada or any provincial or territorial government.

Production of this report is made possible through a financial contribution from Health Canada.

PROSPERO Registration Number: CRD42016036348