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Tran K, Kim J, Tsoi B, et al. Interventions for the Treatment of Obstructive Sleep Apnea in Adults: A Health Technology Assessment – Project Protocol [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2016 Apr. (CADTH Optimal Use Report, No. 6.1a.)

Cover of Interventions for the Treatment of Obstructive Sleep Apnea in Adults: A Health Technology Assessment – Project Protocol

Interventions for the Treatment of Obstructive Sleep Apnea in Adults: A Health Technology Assessment – Project Protocol [Internet].

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APPENDIX 1LITERATURE SEARCH STRATEGY

Clinical Database Search

OVERVIEW
Interface:Ovid
Databases:Embase
MEDLINE Daily and MEDLINE
MEDLINE In-Process & Other Non-Indexed Citations
Cochrane Database of Systematic Reviews (CDSR)
Database of Abstracts of Reviews of Effects (DARE)
Note: Subject headings have been customized for each database. Duplicates between databases were removed in Ovid.
Date of Search:March 2016
Alerts:Monthly search updates until project completion
Study Types:Health technology assessments; systematic reviews; meta-analyses; network meta-analyses; overviews of reviews; and guidelines
Limits:Date limit: 2011-present
Language limit: English- and French-language
Conference abstracts: excluded
SYNTAX GUIDE
/At the end of a phrase, searches the phrase as a subject heading
expExplode a subject heading
*Before a word, indicates that the marked subject heading is a primary topic; or, after a word, a truncation symbol (wildcard) to retrieve plurals or varying endings
adjRequires words are adjacent to each other (in any order)
.tiTitle
.abAbstract
.hwHeading word; usually includes subject headings and controlled vocabulary
.ptPublication type
.kwAuthor keyword (Embase); Keyword (CDSR and DARE)
.kfAuthor keyword heading word (MEDLINE)
.mpMapped term
.yrYear
.jwJournal title word
pmezOvid database code; MEDLINE In-Process & Other Non-Indexed Citations, MEDLINE Daily and Ovid MEDLINE 1946 to Present
oemezdOvid database code; Embase 1974 to present, updated daily
cochOvid database code; Cochrane Database of Systematic Reviews
dareOvid database code; Database of Abstracts of Reviews of Effects
MUTLI-STRATEGY SEARCH
#Searches
1exp sleep apnea syndromes/
2((sleep* or nocturnal) adj2 (apnea* or apnoea*)).ti,ab,kf.
3(sleep* adj3 disordered adj3 breathing).ti,ab,kf.
4((sleep* or nocturnal) adj2 (hypopnea* or hypopnoea* or hypo-apnea* or hypo-apnoea* or apneic-hypopneic or apnoeic-hypopnoeic)).ti,ab,kf.
5((OSA or SAHS) and sleep*).ti,ab,kf.
6OSAHS.ti,ab,kf.
7or/1-6
87 use pmez
9exp sleep disordered breathing/
10((sleep* or nocturnal) adj2 (apnea* or apnoea*)).ti,ab,kw.
11(sleep* adj3 disordered adj3 breathing).ti,ab,kw.
12((sleep* or nocturnal) adj2 (hypopnea* or hypopnoea* or hypo-apnea* or hypo-apnoea* or apneic-hypopneic or apnoeic-hypopnoeic)).ti,ab,kw.
13((OSA or SAHS) and sleep*).ti,ab,kw.
14OSAHS.ti,ab,kw.
15or/9-14
1615 use oemezd
1716 not conference abstract.pt.
188 or 17
19sleep apnea syndromes*.kw.
20sleep apnea, obstructive*.kw.
21((sleep* or nocturnal) adj2 (apnea* or apnoea*)).ti,ab,kw.
22(sleep* adj3 disordered adj3 breathing).ti,ab,kw.
23((sleep* or nocturnal) adj2 (hypopnea* or hypopnoea* or hypo-apnea* or hypo-apnoea* or apneic-hypopneic or apnoeic-hypopnoeic)).ti,ab,kw.
24((OSA or SAHS) and sleep*).ti,ab,kw.
25OSAHS.ti,ab,kw.
26or/19-25
2726 use coch,dare
28meta-analysis.pt.
29meta-analysis/ or systematic review/ or meta-analysis as topic/ or "meta analysis (topic)"/ or "systematic review (topic)"/ or exp technology assessment, biomedical/
30((systematic* adj3 (review* or overview*)) or (methodologic* adj3 (review* or overview*))).ti,ab,kf,kw.
31((quantitative adj3 (review* or overview* or synthes*)) or (research adj3 (integrati* or overview*))).ti,ab,kf,kw.
32((integrative adj3 (review* or overview*)) or (collaborative adj3 (review* or overview*)) or (pool* adj3 analy*)).ti,ab,kf,kw.
33(data synthes* or data extraction* or data abstraction*).ti,ab,kf,kw.
34(handsearch* or hand search*).ti,ab,kf,kw.
35(mantel haenszel or peto or der simonian or dersimonian or fixed effect* or latin square*).ti,ab,kf,kw.
36(met analy* or metanaly* or technology assessment* or HTA or HTAs or technology overview* or technology appraisal*).ti,ab,kf,kw.
37(meta regression* or metaregression*).ti,ab,kf,kw.
38(meta-analy* or metaanaly* or systematic review* or biomedical technology assessment* or bio-medical technology assessment*).mp,hw,kf,kw.
39(medline or cochrane or pubmed or medlars or embase or cinahl).ti,ab,hw.
40(cochrane or (health adj2 technology assessment) or evidence report).jw.
41(comparative adj3 (efficacy or effectiveness)).ti,ab,kf,kw.
42(outcomes research or relative effectiveness).ti,ab,kf,kw.
43((indirect or indirect treatment or mixed treatment) adj4 comparison*).ti,ab,kf,kw.
44(network adj3 (meta-analys* or metaanalys*)).ti,ab,kf,kw.
45(multi* adj3 treatment adj3 comparison*).ti,ab,kf,kw.
46((overview* or review or synthesis or summary or cochrane or analysis) and (reviews or meta-analyses or articles or umbrella)).ti,kf,kw. or umbrella review.ab. or (meta-review or metareview).ti,ab,kf,kw.
47((overview* or reviews) and (systematic or cochrane)).ti,kf,kw.
48(reviews adj2 meta).ab.
49(reviews adj2 (published or quality or included or summar*)).ab.
50cochrane reviews.ab.
51(evidence and (reviews or meta-analyses)).ti,kf,kw.
52or/28-51
5318 and 52
5427 or 53
55(guideline or practice guideline or consensus development conference or consensus development conference, NIH).pt.
56(guideline* or standards or consensus* or recommendat*).ti.
57(practice parameter* or position statement* or policy statement* or CPG or CPGs or best practice*).ti.
58(care adj2 (path or paths or pathway or pathways or map or maps or plan or plans or standard)).ti.
59((critical or clinical or practice) adj2 (path or paths or pathway or pathways or protocol*)).ti.
60(algorithm* and (pharmacotherap* or chemotherap* or chemotreatment* or therap* or treatment* or intervention*)).ti.
61(algorithm* and (screening or examination or test or tested or testing or assessment* or diagnosis or diagnoses or diagnosed or diagnosing)).ti.
62or/55-61
6318 and 62
6454 or 63
65limit 64 to english language [Limit not valid in CDSR,DARE; records were retained]
66limit 64 to french [Limit not valid in CDSR,DARE; records were retained]
6765 or 66
68limit 67 to yr="2011 -Current" [Limit not valid in DARE; records were retained]
69remove duplicates from 68
OTHER DATABASES
PubMedSearched to capture records not indexed in MEDLINE. Same MeSH, keywords and limits used as per MEDLINE search, with appropriate syntax used.

Health Economics Database Search

OVERVIEW
Interface:Ovid
Databases:Embase
MEDLINE Daily and MEDLINE
MEDLINE In-Process & Other Non-Indexed Citations
NHS Economic Evaluation Database (NHS EED) Note: Subject headings have been customized for each database. Duplicates between databases were removed in Ovid.
Date of Search:March 2016
Alerts:Monthly search updates until project completion
Study Types:Economic evaluations
Limits:Date limit: none
Language limit: English- and French-language
Conference abstracts: included
SYNTAX GUIDE
/At the end of a phrase, searches the phrase as a subject heading
expExplode a subject heading
*Before a word, indicates that the marked subject heading is a primary topic; or, after a word, a truncation symbol (wildcard) to retrieve plurals or varying endings
adjRequires words are adjacent to each other (in any order)
.tiTitle
.abAbstract
.hwHeading word; usually includes subject headings and controlled vocabulary
.ptPublication type
.kwAuthor keyword (Embase); Keyword (CDSR and DARE)
.kfAuthor keyword heading word (MEDLINE)
.mpMapped term
.yrYear
.jwJournal title word
pmezOvid database code; MEDLINE In-Process & Other Non-Indexed Citations, MEDLINE Daily and Ovid MEDLINE 1946 to Present
oemezdOvid database code; Embase 1974 to present, updated daily
cleedOvid database code: EBM Reviews - NHS Economic Evaluation Database
.txFull text field (NHS EED)
MULTI-SEARCH STRATEGY
#Searches
1exp sleep apnea syndromes/
2((sleep* or nocturnal) adj2 (apnea* or apnoea*)).ti,ab,kf.
3(sleep* adj3 disordered adj3 breathing).ti,ab,kf.
4((sleep* or nocturnal) adj2 (hypopnea* or hypopnoea* or hypo-apnea* or hypo-apnoea* or apneic-hypopneic or apnoeic-hypopnoeic)).ti,ab,kf.
5((OSA or SAHS) and sleep*).ti,ab,kf.
6OSAHS.ti,ab,kf.
7or/1-6
87 use pmez
9exp sleep disordered breathing/
10((sleep* or nocturnal) adj2 (apnea* or apnoea*)).ti,ab,kw.
11(sleep* adj3 disordered adj3 breathing).ti,ab,kw.
12((sleep* or nocturnal) adj2 (hypopnea* or hypopnoea* or hypo-apnea* or hypo-apnoea* or apneic-hypopneic or apnoeic-hypopnoeic)).ti,ab,kw.
13((OSA or SAHS) and sleep*).ti,ab,kw.
14OSAHS.ti,ab,kw.
15or/9-14
1615 use oemezd
178 or 16
18exp sleep apnea syndromes/
19((sleep* or nocturnal) adj2 (apnea* or apnoea*)).ti,ab,tx.
20(sleep* adj3 disordered adj3 breathing).ti,ab,tx.
21((sleep* or nocturnal) adj2 (hypopnea* or hypopnoea* or hypo-apnea* or hypo-apnoea* or apneic-hypopneic or apnoeic-hypopnoeic)).ti,ab,tx.
22((OSA or SAHS) and sleep*).ti,ab,tx.
23OSAHS.ti,ab,tx.
24or/18-23
2524 use cleed
26*economics/
27exp *"costs and cost analysis"/
28(economic adj2 model*).mp.
29(cost minimi* or cost-utilit* or health utilit* or economic evaluation* or economic review* or cost outcome or cost analys?s or economic analys?s or budget* impact analys?s).ti,ab.
30(cost-effective* or pharmacoeconomic* or pharmaco-economic* or cost-benefit or costs).ti.
31(life year or life years or qaly* or cost-benefit analys?s or cost-effectiveness analys?s).ab.
32(cost or economic*).ti. and (costs or cost-effectiveness or markov).ab.
33or/26-32
3417 and 33
3525 or 34
36limit 35 to english language
37limit 35 to french [Limit not valid in CLEED; records were retained]
3836 or 37
39remove duplicates from 38
OTHER DATABASES
PubMedSearched to capture records not indexed in MEDLINE. Same MeSH, keywords and limits used as per MEDLINE search, with appropriate syntax used.

Patient Experiences and Preferences Database Search

OVERVIEW
Interface:Ovid
Databases:Embase
MEDLINE Daily and MEDLINE
MEDLINE In-Process & Other Non-Indexed Citations
PsycINFO
Note: Subject headings have been customized for each database. Duplicates between databases were removed in Ovid.
Date of Search:March 2016
Alerts:Monthly search updates until project completion
Study Types:Patient experiences and preferences
Limits:Date limit: 2006-present
Language limit: English- and French-language
Conference abstracts: excluded
SYNTAX GUIDE
/At the end of a phrase, searches the phrase as a subject heading
expExplode a subject heading
*Before a word, indicates that the marked subject heading is a primary topic; or, after a word, a truncation symbol (wildcard) to retrieve plurals or varying endings
adjRequires words are adjacent to each other (in any order)
.tiTitle
.abAbstract
.hwHeading word; usually includes subject headings and controlled vocabulary
.ptPublication type
.kwAuthor keyword (Embase); Keyword (CDSR and DARE)
.kfAuthor keyword heading word (MEDLINE)
.mpMapped term
.yrYear
.jwJournal title word
pmezOvid database code; MEDLINE In-Process & Other Non-Indexed Citations, MEDLINE Daily and Ovid MEDLINE 1946 to Present
oemezdOvid database code; Embase 1974 to present, updated daily
psybOvid database code; PsycINFO 1967 to present
freq=2Frequency (must appear at least two times)
MULTI-SEARCH STRATEGY
#Searches
1exp *sleep apnea syndromes/
2((sleep* or nocturnal) adj2 (apnea* or apnoea*)).ti,kf.
3(sleep* adj3 disordered adj3 breathing).ti,kf.
4((sleep* or nocturnal) adj2 (hypopnea* or hypopnoea* or hypo-apnea* or hypo-apnoea* or apneic-hypopneic or apnoeic-hypopnoeic)).ti,kf.
5((OSA or SAHS) and sleep*).ti,kf.
6OSAHS.ti,kf.
7or/1-6
87 use pmez
9exp *sleep disordered breathing/
10((sleep* or nocturnal) adj2 (apnea* or apnoea*)).ti,kw.
11(sleep* adj3 disordered adj3 breathing).ti,kw.
12((sleep* or nocturnal) adj2 (hypopnea* or hypopnoea* or hypo-apnea* or hypo-apnoea* or apneic-hypopneic or apnoeic-hypopnoeic)).ti,kw.
13((OSA or SAHS) and sleep*).ti,kw.
14OSAHS.ti,kw.
15or/9-14
1615 use oemezd
17*sleep apnea/
18((sleep* or nocturnal) adj2 (apnea* or apnoea*)).ti.
19(sleep* adj3 disordered adj3 breathing).ti.
20((sleep* or nocturnal) adj2 (hypopnea* or hypopnoea* or hypo-apnea* or hypo-apnoea* or apneic-hypopneic or apnoeic-hypopnoeic)).ti.
21((OSA or SAHS) and sleep*).ti.
22OSAHS.ti.
23or/17-22
2423 use psyb
258 or 16 or 24
26exp patient acceptance of health care/ or caregivers/
2726 use pmez,psyb
28exp patient attitude/ or patient preference/ or patient participation/ or patient satisfaction/ or patient decision making/ or caregiver/ or relative/ or caregiver burden/ or caregiver support/
2928 use oemezd
30((patient or patients or proband* or individuals or survivor* or family or families or familial or kindred* or relative or relatives or care giver* or caregiver* or carer or carers or personal or spous* or partner or partners or couples or users or participant* or people or child* or teenager* or adolescent* or youth or girls or boys or adults or elderly or females or males or women* or men or men's or mother* or father* or parents or parent or parental or maternal or paternal) and (preference* or preferred or input or experience or experiences or value or values or perspective* or perception* or perceive or perceived or expectation* or choice* or choose* or choosing or "day-to-day" or lives or participat* or acceptance or acceptability or acceptable or accept or accepted or adheren* or adhere or nonadheren* or complian* or noncomplian* or willingness or convenience or convenient or challenges or concerns or limitations or quality of life or satisfaction or satisfied or dissatisfaction or dissatisfied or burden or attitude* or knowledge or belief* or opinion* or understanding or lessons or reaction* or motivation* or motivated or intention* or involvement or engag* or consult* or interact* or dialog* or conversation* or decision* or decide* or deciding or empower* or survey* or focus group* or interview* or questionnaire* or Likert or qualitative or theme* or thematic or barrier* or facilitator*)).ti.
31((patient or patients or proband* or individuals or survivor* or family or families or familial or kindred* or relative or relatives or care giver* or caregiver* or carer or carers) adj2 (preference* or preferred or input or experience or experiences or value or values or perspective* or perception* or perceive or perceived or expectation* or choice* or choose* or choosing or "day-to-day" or lives or participat* or acceptance or acceptability or acceptable or accept or accepted or adheren* or adhere or nonadheren* or complian* or noncomplian* or willingness or convenience or convenient or challenges or concerns or limitations or quality of life or satisfaction or satisfied or dissatisfaction or dissatisfied or burden or attitude* or knowledge or belief* or opinion* or understanding or lessons or reaction* or motivation* or motivated or intention* or involvement or engag* or consult* or interact* or dialog* or conversation* or decision* or decide* or deciding or empower* or survey* or focus group* or interview* or questionnaire* or Likert or qualitative or theme* or thematic or barrier* or facilitator*)).ab,kf.
32((patient or patients or proband* or individuals or survivor* or family or families or familial or kindred* or relative or relatives or care giver* or caregiver* or carer or carers) adj7 (preference* or preferred or input or experience or experiences or value or values or perspective* or perception* or perceive or perceived or expectation* or choice* or choose* or choosing or "day-to-day" or lives or participat* or acceptance or acceptability or acceptable or accept or accepted or adheren* or adhere or nonadheren* or complian* or noncomplian* or willingness or convenience or convenient or challenges or concern or limitations or quality of life or satisfaction or satisfied or dissatisfaction or dissatisfied or burden or attitude* or knowledge or belief* or opinion* or understanding or lessons or reaction* or motivation* or motivated or intention* or involvement or engag* or consult* or interact* or dialog* or conversation* or decision* or decide* or deciding or empower* or survey* or focus group* or interview* or questionnaire* or Likert or qualitative or theme* or thematic or barrier* or facilitator*)).ab. /freq=2
33((personal or spous* or partner or partners or couples or users or participant* or people or child* or teenager* or adolescent* or youth or girls or boys or adults or elderly or females or males or women* or men or men's or mother* or father* or parents or parent or parental or maternal or paternal) adj2 (preference* or preferred or input or experience or experiences or value or values or perspective* or perception* or perceive or perceived or expectation* or choice* or choose* or choosing or "day-to-day" or lives or participat* or acceptance or acceptability or acceptable or accept or accepted or adheren* or adhere or nonadheren* or complian* or noncomplian* or willingness or convenience or convenient or challenges or concerns or limitations or quality of life or satisfaction or satisfied or dissatisfaction or dissatisfied or burden or attitude* or knowledge or belief* or opinion* or understanding or lessons or reaction* or motivation* or motivated or intention* or involvement or engag* or consult* or interact* or dialog* or conversation* or decision* or decide* or deciding or empower* or survey* or focus group* or interview* or questionnaire* or Likert or qualitative or theme* or thematic or barrier* or facilitator*)).ab. /freq=2
34(patient adj (reported or centered* or centred* or focused)).ti,ab,kf.
35(treatment* adj2 (satisf* or refus*)).ti,ab,kf.
36(lived experience* or shared decision making).ti,ab,kf.
37or/27,29-36
3825 and 37
39limit 38 to yr="2006 -Current"
4039 not conference abstract.pt.
41limit 40 to english language
42limit 40 to french
4341 or 42
44remove duplicates from 43
OTHER DATABASES
PubMedSearched to capture records not indexed in MEDLINE. Same MeSH, keywords and limits used as per MEDLINE search, with appropriate syntax used.
CINAHLSearched to capture records not indexed in MEDLINE. Same MeSH, keywords and limits used as per MEDLINE search, with appropriate syntax used, including the addition of CINAHL headings.

Ethics Implications Database Search

OVERVIEW
Interface:Ovid
Databases:MEDLINE Daily and MEDLINE
MEDLINE In-Process & Other Non-Indexed Citations
Note: Duplicates between databases were removed in Ovid.
Date of Search:March 2016
Alerts:Monthly search updates until project completion
Study Types:Ethics/Legal/Social
Limits:Date limit: none
Language limit: English- and French-language
SYNTAX GUIDE
/At the end of a phrase, searches the phrase as a subject heading
expExplode a subject heading
*Before a word, indicates that the marked subject heading is a primary topic; or, after a word, a truncation symbol (wildcard) to retrieve plurals or varying endings
adjRequires words are adjacent to each other (in any order)
.tiTitle
.abAbstract
.hwHeading word; usually includes subject headings and controlled vocabulary
.kfAuthor keyword heading word
.fsFloating subheading
MULTI-STRATEGY SEARCH
#Searches
1exp Ethics/
2exp Privacy/
3exp Sociology/
4exp Jurisprudence/
5exp Psychology, Social/
6"Legislation & Jurisprudence".fs.
7ethics.fs.
8exp Geography, Medical/
9exp Environmental Pollution/
10Medically Underserved Area/
11(waste* or pollution or polluting or contamination or contaminated).ti,ab,kf.
12((Healthcare or Health Care or nonclinical or Community Based) adj (Deliver* or Distribution* or System*)).ti,ab,kf.
13(geographic adj (region* or area*)).ti,ab,kf.
14(remote or urban or rural).ti,ab,kf.
15(ethic or ethics or ethical or moral* or bioethic*).ti,ab,hw,kf.
16(legal* or liabilit* or litigation* or constitutional or justice or law or laws or jurisprudence or complicit*).ti,ab,hw,kf.
17(lawsuit* or lawyer* or lawmaker*).ti,ab,kf.
18human right*.ti,ab,kf.
19civil right*.ti,ab,kf.
20(prejudice* or stigma or stigmas or stigmatization or stigmatize or stigmatise or stigmatisation or inequalit* or fairness).ti,ab,kf.
21((care or treatment) adj2 (duty or obligat*)).ti,ab,kf.
22(social* adj (responsibl* or obligat*)).ti,ab,kf.
23(communitarian* or beneficence or nonmaleficence or non-maleficence or accountability).ti,ab,kf.
24harm.ti,ab,kf.
25(privacy or private or confidential*).ti,ab,hw,kf.
26((informed or presumed) adj2 (consent or choice or decision making)).ti,ab,kf.
27autonomy.ti,ab,hw,kf.
28transparency.ti,ab,kf.
29or/1-28
30exp *sleep apnea syndromes/
31((sleep* or nocturnal) adj2 (apnea* or apnoea*)).ti,kf.
32(sleep* adj3 disordered adj3 breathing).ti,kf.
33((sleep* or nocturnal) adj2 (hypopnea* or hypopnoea* or hypo-apnea* or hypo-apnoea* or apneic-hypopneic or apnoeic-hypopnoeic)).ti,kf.
34((OSA or SAHS) and sleep*).ti,kf.
35OSAHS.ti,kf.
36or/30-35
3729 and 36
38limit 37 to english language
39limit 37 to french
4038 or 39
41remove duplicates from 40
OTHER DATABASES
PubMedSearched to capture records not indexed in MEDLINE. Same MeSH, keywords and limits used as per MEDLINE search, with appropriate syntax used.
CINAHLSearched to capture records not indexed in MEDLINE. Same MeSH, keywords and limits used as per MEDLINE search, with appropriate syntax used, including the addition of CINAHL headings.

Grey Literature

Dates for Search:March 2016
Keywords:Sleep apnea, obstructive sleep apnea, sleep disordered breathing
Limits:Publication years: HTA/SR/MA — 2011 to present; Economics — no date limit; Patient experiences and preferences — 2006 to present; Ethics — no date limit

Relevant websites from the following sections of the CADTH grey literature checklist, “Grey matters: a practical tool for searching health-related grey literature” (https://www.cadth.ca/grey-matters), will be searched:

  • Health Technology Assessment Agencies
  • Health Economics
  • Clinical Practice Guidelines
  • Databases (free)
  • Internet Search
  • Open Access Journals.

Copyright © 2016 CADTH.

Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

Bookshelf ID: NBK362695

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