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National Toxicology Program. NTP Technical Report on the Toxicology and Carcinogenesis Studies of Di(2-ethylhexyl) Phthalate (CASRN 117-81-7) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats: Technical Report 601 [Internet]. Research Triangle Park (NC): National Toxicology Program; 2021 Dec.

Cover of NTP Technical Report on the Toxicology and Carcinogenesis Studies of Di(2-ethylhexyl) Phthalate (CASRN 117-81-7) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats

NTP Technical Report on the Toxicology and Carcinogenesis Studies of Di(2-ethylhexyl) Phthalate (CASRN 117-81-7) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats: Technical Report 601 [Internet].

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Contributors

  • Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Provided oversight for external peer review
    S.L. Scruggs, Ph.D.
    M.S. Wolfe, Ph.D.
  • Kelly Government Services, Research Triangle Park, North Carolina, USA
    Supported external peer review
    E.A. Maull, Ph.D. (retired from NIEHS, Research Triangle Park, North Carolina, USA)
  • NTP Pathology Working Group, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Participated in NTP Pathology Working Group on perinatal and postweaning rats (Study 1) and postweaning-only rats (Study 2) (August 14, 2018)
    N. Barlow, D.V.M., Ph.D., Seattle Genetics, Inc.
    M.F. Cesta, D.V.M., Ph.D., National Institute of Environmental Health Sciences
    S.A. Elmore, D.V.M., M.S., National Institute of Environmental Health Sciences
    R.A. Herbert, D.V.M., Ph.D., National Institute of Environmental Health Sciences
    R.C. Kovi, M.V.Sc., Ph.D., Experimental Pathology Laboratories, Inc.
    D.E. Malarkey, D.V.M., Ph.D., National Institute of Environmental Health Sciences
    C.J. Willson, D.V.M., Ph.D., Integrated Laboratory Systems, LLC
  • NTP Pathology Peer Review, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Participated in NTP Pathology Peer Review on control rat hearts (Study 1 and Study 2) (April 14, 2016)
    M.F. Cesta, D.V.M., Ph.D., National Institute of Environmental Health Sciences
    S.A. Elmore, D.V.M., M.S., National Institute of Environmental Health Sciences
    M.P. Jokinen, D.V.M., Integrated Laboratory Systems, LLC
    D.E. Malarkey, D.V.M., Ph.D., National Institute of Environmental Health Sciences
  • Participated in NTP Pathology Peer Review on brain glial cell proliferative lesions (Study 1 and Study 2) (April 18, 2016)
    M.F. Cesta, D.V.M., Ph.D., National Institute of Environmental Health Sciences
    P. Little, D.V.M., Ph.D., Experimental Pathology Laboratories, Inc.
    D.E. Malarkey, D.V.M., Ph.D., National Institute of Environmental Health Sciences
  • Participated in NTP Pathology Peer Review on brain granular cell proliferative lesions and head/neck schwannomas and sarcomas (Study 1 and Study 2) (April 18, 2016)
    M.F. Cesta, D.V.M., Ph.D., National Institute of Environmental Health Sciences
    P. Little, D.V.M., Ph.D., Experimental Pathology Laboratories, Inc.
    D.E. Malarkey, D.V.M., Ph.D., National Institute of Environmental Health Sciences
  • Performed special review of testis lesions (Study 1) (September 5, 2018)
    K.Y. Cimon, D.V.M., Experimental Pathology Laboratories, Inc.
  • Experimental Pathology Laboratories, Inc., Research Triangle Park, North Carolina, USA
    Supervised pathology review
    T.J. Steinbach, D.V.M., Principal Investigator
    G.A. Willson, B.V.M.S., Principal Investigator
  • Integrated Laboratory Systems, LLC, Research Triangle Park, North Carolina, USA
    Conducted micronucleus assays
    R.R. Tice, Ph.D., Principal Investigator
  • Brookhaven National Laboratory, Upton, New York, USA
    Conducted chromosomal aberration and micronucleus assays
    R.R. Tice, Ph.D., Principal Investigator
  • CSS Corporation, Research Triangle Park, North Carolina, USA
    Prepared quality assessment audits
    S. Brecher, Ph.D., Principal Investigator
    S. Iyer, B.S.
    V.S. Tharakan, D.V.M.
  • Social & Scientific Systems, a DLH Company, Research Triangle Park, North Carolina, USA
    Provided statistical analyses
    S.J. McBride, Ph.D., Principal Investigator
    L.J. Betz, M.S.
    S.F. Harris, M.S.
    J.D. Krause, Ph.D.
  • ICF, Fairfax, Virginia, USA
    Provided contract oversight
    D. Burch, M.E.M., Principal Investigator
    J. Cleland, M.E.M.
    J.A. Wignall, M.S.P.H.
  • Prepared and edited report
    K.S. Duke, Ph.D.
    T. Hamilton, M.S.
    B. Ingle, Ph.D.
    K. McKinley, M.E.M.
    M.E. McVey, Ph.D.
    J.I. Powers, M.A.P.
    K.E. Setty, Ph.D.
    K.A. Shipkowski, Ph.D.
    S.J. Snow, Ph.D.
    J.W. Tracy, M.H.S.
  • Supported external peer review
    C.N. Byrd, B.S.
    L.M. Green, M.P.H.
    M.C. Rooney, B.A.
    A.J. Schumacher, B.A.
Copyright Notice

This is a work of the US government and distributed under the terms of the Public Domain

Bookshelf ID: NBK579328
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