U.S. flag

An official website of the United States government

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

National Toxicology Program. NTP Research Report on the Scoping Review of Prenatal Exposure to Progestogens and Adverse Health Outcomes: Research Report 17 [Internet]. Research Triangle Park (NC): National Toxicology Program; 2020 Sep.

Cover of NTP Research Report on the Scoping Review of Prenatal Exposure to Progestogens and Adverse Health Outcomes

NTP Research Report on the Scoping Review of Prenatal Exposure to Progestogens and Adverse Health Outcomes: Research Report 17 [Internet].

Show details

Appendix ALiterature Search Strategy

The literature search involved three databases: PubMed, Cochrane Library, and Database of Abstracts of Reviews of Effects (DARE). The literature search for PubMed included a separate set of search terms from the literature search for Cochrane Library and DARE databases (Table A-1 and Table A-2).

Table A-1PubMed Database Search Terms

SetSearch Terms
Exposure/Progestogens((Progesterone[mh] OR progesterone-congeners[mh] OR progestins[mh] OR exogenous-progesterone[tiab] OR Algestone[tiab] OR Algestone-acetophenide[tiab] OR Allylestrenol[tiab] OR Chlormadinone-acetate[tiab] OR cyproterone-acetate[tiab] OR desogestrel[tiab] OR dydrogesterone[tiab] OR Ethisterone[tiab] OR ethynodiol-diacetate[tiab] OR Flurogestone-acetate[tiab] OR Gestonorone-caproate[tiab] OR Gestrinone[tiab] OR Levonorgestrel[tiab] OR Lynestrenol[tiab] OR medrogestone[tiab] OR medroxyprogesterone-acetate[tiab] OR Megestrol-acetate[tiab] OR Norethindrone[tiab] OR norethynodrel[tiab] OR Norgestrel[tiab] OR Promegestone[tiab] OR 11-hydroxyprogesterone[tiab] OR 17-alpha-hydroxy-progesterone-caproate[tiab] OR 17-alpha-hydroxyprogesterone-caproate[tiab] OR 17-hydroxyprogesterone-caproate[tiab] OR Demegestone[tiab] OR Dienogest[tiab] OR Drospirenone[tiab] OR Etonogestrel[tiab] OR Gestodene[tiab] OR Nomegestrol-acetate[tiab] OR Norelgestromin[tiab] OR Norethindrone-acetate[tiab] OR Norgestimate[tiab] OR ST-1435[tiab] OR Trimegestone[tiab] OR 11-hydroxyprogesterone[nm] OR 17-alpha-hydroxy-progesterone-caproate[nm] OR Demegestone[nm] OR Dienogest[nm] OR Drospirenone[nm] OR Etonogestrel[nm] OR Gestodene[nm] OR Nomegestrol-acetate[nm] OR Norelgestromin[nm] OR Norethindrone-acetate[nm] OR Norgestimate[nm] OR ST-1435[nm] OR Trimegestone[nm] OR Algestone[mh] OR Algestone-acetophenide[mh] OR Allylestrenol[mh] OR Chlormadinone-acetate[mh] OR cyproterone-acetate[mh] OR desogestrel[mh] OR dydrogesterone[mh] OR Ethisterone[mh] OR ethynodiol-diacetate[mh] OR Flurogestone-acetate[mh] OR Gestonorone-caproate[mh] OR Gestrinone[mh] OR Levonorgestrel[mh] OR Lynestrenol[mh] OR medrogestone[mh] OR medroxyprogesterone-acetate[mh] OR Megestrol-acetate[mh] OR Norethindrone[mh] OR norethynodrel[mh] OR Norgestrel[mh] OR Promegestone[mh] OR progestogens[tiab] OR progestogen[tiab] OR Hydroxyprogesterone-caproate[tiab]) OR ((progesterone[tiab] OR progestins[tiab]) NOT medline[sb]))
Window of ExposureAND
(animals,-newborn[mh] OR child[mh] OR infant[mh] OR maternal-exposure[mh] OR Maternal-Fetal Exchange[mh] OR babies[tiab] OR baby[tiab] OR child*[tiab] OR embryo[tiab] OR embryonic[tiab] OR embryos[tiab] OR fetal[tiab] OR fetus[tiab] OR foetal[tiab] OR gestation*[tiab] OR infant*[tiab] OR in-utero[tiab] OR maternal[tiab] OR neonat*[tiab] OR newborn*[tiab] OR offspring[tiab] OR perinat*[tiab] OR postnat*[tiab] OR prenat*[tiab] OR progeny[tiab] OR pups[tiab])
OutcomeAND
(pregnancy-outcomes[mh] OR prenatal-exposure-delayed-effects[mh] OR premature-birth[mh] OR premature-birth[tiab] OR abortion,-spontaneous[mh] OR spontaneous-abortion[tiab] OR live-born[tiab] OR still-born[tiab] OR stillborn[tiab] OR stillbirth[tiab] OR still-birth[tiab] OR Congenital-Abnormality[tiab] OR Congenital-Abnormalities[tiab] OR Congenital-Abnormalities[mh] OR Deformities[tiab] OR Deformity[tiab] OR Congenital-defect[tiab] OR Congenital-defects[tiab] OR birth-defects[tiab] OR birth-defect[tiab] OR Congenital-anomalies[tiab] OR Congenital-anomaly[tiab] OR hypospadias[tiab] OR Behavior-and-Behavior-Mechanisms[mh] OR Gene-Expression-Regulation[mh] OR Glucuronosyltransferase[mh] OR Intelligence-tests[mh] OR Malate-Dehydrogenase[mh] OR Mediator-Complex-Subunit-1[mh] OR Mental-disorders[mh] OR Mental-processes[mh] OR Monocarboxylic-Acid-Transporters[mh] OR Myelin-Basic-Protein[mh] OR nervous-system[mh] OR nervous-system-diseases[mh] OR nervous-system-physiological-phenomena[mh] OR Neurogranin[mh] OR Oligodendroglia[mh] OR Peroxisome-Proliferator-Activated-Receptors[mh] OR Psychological-Phenomena-and-Processes[mh] OR Academic-performance[tiab] OR auditory[tiab] OR cortical[tiab] OR delayed-development[tiab] OR developmental-impairment[tiab] OR developmental-delay*[tiab] OR developmental-disorder*[tiab] OR euthyroid[tiab] OR gait[tiab] OR glia*[tiab] OR gliogenesis[tiab] OR hyperactiv*[tiab] OR impulse-control[tiab] OR IQ[tiab] OR ischemi*[tiab] OR locomotor[tiab] OR mental-deficiency[tiab] OR mental-development[tiab] OR mental-illness[tiab] OR mental-deficit[tiab] OR mobility[tiab] OR mood[tiab] OR morris-maze[tiab] OR morris-water[tiab] OR motor-abilit*[tiab] OR Motor-activities[tiab] OR motor-performance[tiab] OR nerve[tiab] OR neural[tiab] OR neurobehav*[tiab] OR Neurocognitive-impairment[tiab] OR neurodegenerat*[tiab] OR Neurodevelopment*[tiab] OR neurodisease*[tiab] OR neurologic*[tiab] OR neuromuscular[tiab] OR neuron*[tiab] OR neuropath*[tiab] OR obsessive-compulsive[tiab] OR OCD[tiab] OR olfaction[tiab] OR olfactory[tiab] OR open-field-test[tiab] OR passive-avoidance[tiab] OR plasticity[tiab] OR sociab*[tiab] OR speech*[tiab] OR spelling[tiab] OR stereotypic-movement*[tiab] OR synap*[tiab] OR tauopath*[tiab] OR visual-motor[tiab] OR Visuospatial-processing[tiab] OR water-maze[tiab] OR active-avoidance[tiab] OR ADHD[tiab] OR amygdala[tiab] OR antisocial[tiab] OR anxiety[tiab] OR anxious[tiab] OR asperger*[tiab] OR attention-deficit[tiab] OR autism[tiab] OR autistic[tiab] OR behavioral[tiab] OR behaviors[tiab] OR behavioural[tiab] OR behaviours[tiab] OR bipolar[tiab] OR cerebellum[tiab] OR cognition[tiab] OR cognitive[tiab] OR comprehension[tiab] OR cranial[tiab] OR dementia[tiab] OR dendrit*[tiab] OR dentate-gyrus[tiab] OR depression[tiab] OR down-syndrome[tiab] OR dyslexia[tiab] OR entorhinal-cortex[tiab] OR epilep*[tiab] OR ganglia*[tiab] OR ganglion*[tiab] OR hearing[tiab] OR hippocamp*[tiab] OR human-development[tiab] OR impulsiv*[tiab] OR Intellectual-disability[tiab] OR intelligence[tiab] OR language[tiab] OR learning[tiab] OR lewy-bod*[tiab] OR long-term-potentiation[tiab] OR long-term-synaptic-depression[tiab] OR memory[tiab] OR mental-disorder*[tiab] OR mental-recall[tiab] OR Motor-activity[tiab] OR motor-skill*[tiab] OR myxedema[tiab] OR Nervous-system[tiab] OR nervous-system[tiab] OR neurit*[tiab] OR optic[tiab] OR palsy[tiab] OR panic[tiab] OR parahippocamp*[tiab] OR paranoia[tiab] OR paranoid[tiab] OR perception[tiab] OR perforant*[tiab] OR personality[tiab] OR phobia[tiab] OR problem-solving[tiab] OR proprioception[tiab] OR psychomotor[tiab] OR reflex[tiab] OR risk-taking[tiab] OR schizophrenia[tiab] OR seizure*[tiab] OR sensation*[tiab] OR sleep[tiab] OR smell[tiab] OR spatial-behavior[tiab] OR substantia-nigra[tiab] OR child-development[mh] OR child-development[tiab] OR acanthoma*[tiab] OR acrochord*[tiab] OR acrospiroma*[tiab] OR adamantinoma*[tiab] OR adenoacanthoma*[tiab] OR adenoameloblast*[tiab] OR adenocarcin*[tiab] OR adenofibrom*[tiab] OR adenol*[tiab] OR adenom*[tiab] OR adenosquamous[tiab] OR ameloblast*[tiab] OR androblast*[tiab] OR angiofib*[tiab] OR angiog*[tiab] OR angiok*[tiab] OR angiol*[tiab] OR angiom*[tiab] OR angiomatosis[mh] OR angiosarc*[tiab] OR antibodies, neoplasm[mh] OR antigens, neoplasm[mh] OR apudom*[tiab] OR argentaffin*[tiab] OR arrhenoblast*[tiab] OR astroblast*[tiab] OR astrocytom*[tiab] OR astrogliom*[tiab] OR atypia[tiab] OR baltoma[tiab] OR barrett esophagus[mh] OR blastom*[tiab] OR cancer[tiab] OR cancero*[tiab] OR cancers[tiab] OR carcinog*[tiab] OR carcinogenicity tests[mh] OR carcinogens[mh] OR carcinoid*[tiab] OR carcinom*[tiab] OR carcinos*[tiab] OR cavernom*[tiab] OR cell line, tumor[mh] OR cementom*[tiab] OR cerumin*[tiab] OR chloroma*[tiab] OR cholangio*[tiab] OR chondrob*[tiab] OR chondrom*[tiab] OR chondros*[tiab] OR chord*[tiab] OR chorioa*[tiab] OR choriocarc*[tiab] OR chorioep*[tiab] OR chorionep*[tiab] OR chromaffinom*[tiab] OR collagenom*[tiab] OR comedocarcinom*[tiab] OR condylom*[tiab] OR condylomata acuminata[mh] OR corticotrop*[tiab] OR craniopharyng*[tiab] OR cylindrom*[tiab] OR cystadeno*[tiab] OR cystoma*[tiab] OR cystosa*[tiab] OR dentinom*[tiab] OR dermatofibro*[tiab] OR dermoid[tiab] OR desmoid[tiab] OR desmoplastic*[tiab] OR dictyota[tiab] OR dysgerm*[tiab] OR dyskerat*[tiab] OR dysmyelopoiesis[tiab] OR dysplas*[tiab] OR ectomesenchym*[tiab] OR elastofibr*[tiab] OR enchondrom*[tiab] OR endotheliom*[tiab] OR ependymo*[tiab] OR epidermoid*[tiab] OR epitheliom*[tiab] OR erythrol*[tiab] OR erythropl*[tiab] OR esthesioneuro*[tiab] OR etiolog*[tiab] OR fibroaden*[tiab] OR fibrochond*[tiab] OR fibroe*[tiab] OR fibrofol*[tiab] OR fibroid*[tiab] OR fibrolip*[tiab] OR fibrom*[tiab] OR fibroodontom*[tiab] OR fibrosarcom*[tiab] OR fibrothecom*[tiab] OR fibroxantho*[tiab] OR ganglioblast*[tiab] OR gangliocytom*[tiab] OR gangliogliom*[tiab] OR ganglioneuro*[tiab] OR gastrinom*[tiab] OR genes, neoplasm[mh] OR germinom*[tiab] OR glioblast*[tiab] OR gliom*[tiab] OR glomangio*[tiab] OR glucagonom*[tiab] OR gonadoblastom*[tiab] OR gonocytom*[tiab] OR gynandroblastom*[tiab] OR haemangio*[tiab] OR hamartom*[tiab] OR hemangio*[tiab] OR hepatoblastom*[tiab] OR hepatom*[tiab] OR hibernom*[tiab] OR hidradenom*[tiab] OR hidrocy*[tiab] OR hodgkin*[tiab] OR hydatidiform*[tiab] OR hydradenom*[tiab] OR hypernephrom*[tiab] OR IARC[tiab] OR immunocytom*[tiab] OR insulinom*[tiab] OR leiomyo*[tiab] OR lesion*[tiab] OR leukaemia*[tiab] OR leukemia*[tiab] OR leukoplak*[tiab] OR leukostas*[tiab] OR leukostasis[mh] OR lipoadenom*[tiab] OR lipoblastom*[tiab] OR lipom*[tiab] OR liposarcom*[tiab] OR luteinom*[tiab] OR luteom*[tiab] OR lymphangio*[tiab] OR lymphoepitheliom*[tiab] OR lymphom*[tiab] OR lymphoscintigraph*[tiab] OR macroglobulinem*[tiab] OR macroprolactinom*[tiab] OR malignan*[tiab] OR maltom*[tiab] OR masculinovoblastom*[tiab] OR mastocyto*[tiab] OR mcf-7[tiab] OR medullo*[tiab] OR meigs syndrome[tiab] OR melanoa*[tiab] OR melanocytom*[tiab] OR melanom*[tiab] OR meningio*[tiab] OR mesenchymom*[tiab] OR mesonephrom*[tiab] OR mesotheliom*[tiab] OR metaplas*[tiab] OR metaplasia[mh] OR metastas*[tiab] OR metastat*[tiab] OR microgliom*[tiab] OR micrometastas*[tiab] OR mucositis[mh] OR mycosis fungoides*[tiab] OR myelodysplas*[tiab] OR myelodysplastic syndromes[mh] OR myelodysplastic-myeloproliferative diseases[mh] OR myelofibrosis[tiab] OR myelol*[tiab] OR myeloma*[tiab] OR myeloproliferat*[tiab] OR myeloproliferative disorders[mh] OR myelosuppression*[tiab] OR myoblastom*[tiab] OR myoepitheliom*[tiab] OR myofibro*[tiab] OR myolipom*[tiab] OR myoma*[tiab] OR myosarcom*[tiab] OR myxof*[tiab] OR myxom*[tiab] OR naevus[tiab] OR neoplas*[tiab] OR neoplasm proteins[mh] OR neoplasms[mh] OR neoplastic stem cells[mh] OR nephroblastom*[tiab] OR neurilem*[tiab] OR neurinom*[tiab] OR neuroblastom*[tiab] OR neurocytom*[tiab] OR neuroepitheliom*[tiab] OR neurofibro*[tiab] OR neurolipocytom*[tiab] OR neuroma*[tiab] OR neuronevus[tiab] OR neurothekeom*[tiab] OR nevus[tiab] OR non coding RNA[tiab] OR nonseminom*[tiab] OR odontoam*[tiab] OR odontom*[tiab] OR oligoastrocytom*[tiab] OR oligodendrogliom*[tiab] OR oncocytom*[tiab] OR oncogen*[tiab] OR oncogene fusion[mh] OR oncogene proteins[mh] OR oncogenic viruses[mh] OR oncolog*[tiab] OR oncolytic viruses[mh] OR oncoprotein*[tiab] OR opsoclonus-myoclonus[tiab] OR orchioblastom*[tiab] OR osteoblastom*[tiab] OR osteoch*[tiab] OR osteofibrosarcom*[tiab] OR osteom*[tiab] OR osteosarcom*[tiab] OR pancreatoblastom*[tiab] OR papillom*[tiab] OR parachordom*[tiab] OR paragangliom*[tiab] OR paraneoplas*[tiab] OR perineuriom*[tiab] OR phaeochromocytom*[tiab] OR pheochromo*[tiab] OR pilomatri*[tiab] OR plasmacytom*[tiab] OR pneumoblast*[tiab] OR pneumocytom*[tiab] OR polyembryom*[tiab] OR polyhistiom*[tiab] OR polyp[tiab] OR polyps[mh] OR porocarcinom*[tiab] OR porom*[tiab] OR pre-cancer*[tiab] OR precancer*[tiab] OR preleukaem*[tiab] OR preleukem*[tiab] OR prelymphom*[tiab] OR pre-lymphom*[tiab] OR pre-malign*[tiab] OR premalignan*[tiab] OR preneoplas*[tiab] OR pre-neoplas*[tiab] OR prolactinom*[tiab] OR protooncogen*[tiab] OR pseudotum*[tiab] OR reninom*[tiab] OR retinoblastom*[tiab] OR rhabdo*[tiab] OR RNA, neoplasm[mh] OR sarcoma*[tiab] OR schwannom*[tiab] OR SEER program[mh] OR seminom*[tiab] OR sentinel lymph node[tiab] OR sentinel lymph node biopsy[mh] OR sertoli-leydig cell tumor[tiab] OR sezary syndrome[tiab] OR somatostatinom*[tiab] OR somatotropinom*[tiab] OR spermatocytom*[tiab] OR spiradenom*[tiab] OR spongioblastom*[tiab] OR subependymom*[tiab] OR thecom*[tiab] OR thymom*[tiab] OR trichilemmom*[tiab] OR trichoadenom*[tiab] OR trichoblastom*[tiab] OR trichodiscom*[tiab] OR trichoepitheliom*[tiab] OR trichofolliculom*[tiab] OR tricholemm*[tiab] OR tumor[tiab] OR tumor markers, biological[mh] OR tumorgen*[tiab] OR tumorig*[tiab] OR tumor-inhibit*[tiab] OR tumorog*[tiab] OR tumors[tiab] OR tumors[tiab] OR tumour[tiab] OR up-regulat*[tiab] OR vipom*[tiab] OR waldenstrom*[tiab] OR xanthoma*[tiab])

Table A-2Cochrane and DARE (Database of Abstracts of Reviews of Effects) Database Search Terms

SetSearch Strategy
Exposure/Progestogens(exogenous-progesterone OR Algestone OR Algestone-acetophenide OR Allylestrenol OR Chlormadinone-acetate OR cyproterone-acetate OR desogestrel OR dydrogesterone OR Ethisterone OR ethynodiol-diacetate OR Flurogestone-acetate OR Gestonorone-caproate OR Gestrinone OR Levonorgestrel OR Lynestrenol OR medrogestone OR medroxyprogesterone-acetate OR Megestrol-acetate OR Norethindrone OR norethynodrel OR Norgestrel OR Promegestone OR 11-hydroxyprogesterone OR 17-alpha-hydroxy-progesterone-caproate OR 17-alpha-hydroxyprogesterone-caproate OR 17-hydroxyprogesterone-caproate OR Demegestone OR Dienogest OR Drospirenone OR Etonogestrel OR Gestodene OR Nomegestrol-acetate OR Norelgestromin OR Norethindrone-acetate OR Norgestimate OR ST-1435 OR Trimegestone OR progesterone OR progestins OR progestogens OR progestogen OR Hydroxyprogesterone-caproate)
Window of ExposureAND
(babies OR baby OR child* OR embryo OR embryonic OR embryos OR fetal OR fetus OR foetal OR gestation* OR infant* OR in-utero OR maternal OR neonat* OR newborn* OR offspring OR perinat* OR postnat* OR prenat* OR progeny OR pups)
Copyright Notice

This is a work of the US government and distributed under the terms of the Public Domain

Bookshelf ID: NBK564162

Views

  • PubReader
  • Print View
  • Cite this Page
  • PDF version of this title (958K)

Other titles in this collection

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...