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Irwin RD, Malarkey DE, Bristol DW, et al. NTP Genetically Modified Model Report on the Toxicity Studies of Acesulfame Potassium (CASRN 55589-62-3) in FVB/N-TgN(v-Ha-ras)Led (Tg.AC) Hemizygous Mice and Carcinogenicity Studies of Acesulfame Potassium in B6.129-Trp53tm1Brd (N5) Haploinsufficient Mice (Feed Studies): NTP GMM 02 [Internet]. Research Triangle Park (NC): National Toxicology Program; 2005 Oct.

Cover of NTP Genetically Modified Model Report on the Toxicity Studies of Acesulfame Potassium (CASRN 55589-62-3) in FVB/N-TgN(v-Ha-ras)Led (Tg.AC) Hemizygous Mice and Carcinogenicity Studies of Acesulfame Potassium in B6.129-Trp53tm1Brd (N5) Haploinsufficient Mice (Feed Studies)

NTP Genetically Modified Model Report on the Toxicity Studies of Acesulfame Potassium (CASRN 55589-62-3) in FVB/N-TgN(v-Ha-ras)Led (Tg.AC) Hemizygous Mice and Carcinogenicity Studies of Acesulfame Potassium in B6.129-Trp53tm1Brd (N5) Haploinsufficient Mice (Feed Studies): NTP GMM 02 [Internet].

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CONTRIBUTORS

National Toxicology Program

Evaluated and interpreted results and reported findings

  • R.D. Irwin, Ph.D., Study Scientist
  • D.E. Malarkey, D.V.M., Ph.D., Study Pathologist
  • D.W. Bristol, Ph.D.
  • J.R. Bucher, Ph.D.
  • J.E. French, Ph.D.
  • J.R. Hailey, D.V.M.
  • J.K. Haseman, Ph.D.
  • R.A. Herbert, D.V.M., Ph.D.
  • R.R. Maronpot, D.V.M.
  • J.C. Peckham, D.V.M., M.S., Ph.D.
  • J.H. Roycroft, Ph.D.
  • C.S. Smith, Ph.D.
  • G.S. Travlos, D.V.M.
  • M.K. Vallant, B.S., M.T.
  • K.L. Witt, M.S.

BioReliance Corporation

Conducted studies and evaluated pathology findings

  • M.L. Wenk, Ph.D., Principal Investigator
  • L.L. Lanning, D.V.M.

Experimental Pathology Laboratories, Inc.

Provided pathology review

  • J.F. Hardisty, D.V.M., Principal Investigator
  • G. Willson, B.V.M. & S.

Dynamac Corporation

Prepared quality assurance audits

  • S. Brecher, Ph.D., Principal Investigator

NTP Pathology Working Group

Evaluated slides and prepared pathology report (December 18, 2001)

  • C.A. Cummings, D.V.M., Ph.D., Chairperson Pathology Associates, A Charles River Company Laboratories, Inc.
  • J. Mahler, D.V.M.
    National Toxicology Program

Constella Group, Inc.

Provided statistical analyses

  • P.W. Crockett, Ph.D., Principal Investigator
  • L.J. Betz, M.S.
  • K.P. McGowan, M.B.A.
  • J.T. Scott, M.S.

Biotechnical Services, Inc.

Prepared Report

  • S.R. Gunnels, M.A., Principal Investigator
  • B.F. Hall, M.S.
  • L.M. Harper, B.S.
  • D.C. Serbus, Ph.D.
  • R.A. Willis, B.A., B.S.
Copyright Notice

This is a work of the US government and distributed under the terms of the Public Domain

Bookshelf ID: NBK576276

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