HISTORICAL CONTROL INCIDENCES

J.E.A. Leakey; W.T. Allaben; J.K. Dunnick; F.W. Lee; S.M. Lewis; P.C. Howard; C.C. Weis; D.D. Paine; S.M. Billedeau; B.R. Brown; J.P Freeman; J. Moody; L.K. Schoenbachler; P.H. Siitonen; S.J. Culp; J.M. Fowler; R.D. Smith; S. Appana; S.J. Baek; R.P. Felton; B.T. Thorn; C.J. Cain; J.W. Carson; A. Matson; K.A. Carroll; S.H. Green; P.W. Mellick; G.R. Olson; A.R. Warbritton; L.P. Wiley; M.H. Hamlin, II; J.F. Hardisty; R.A. Miller; J.F. Hardisty; J.M. Cullen; S.A. Elmore; D.E. Malarkey; P.W. Mellick; R.A. Miller; G.R. Olson; P.C. Howard; W.T. Allaben; N.J. Walker; J.R. Bucher; S.R. Gunnels; L.M. Harper; E.S. Rathman; D.C. Serbus

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Leakey JEA, Allaben WT, Dunnick JK, et al. NTP Genetically Modified Model Report on the Toxicology and Carcinogenicity Studies of 3’-Azido-3’-Deoxythymidine (CASRN 30516-87-1) in Genetically Modified C3B6.129F1-Trp53tm1Brd N12 Haploinsufficient Mice (In Utero and Postnatal Gavage Study): NTP GMM 14 [Internet]. Research Triangle Park (NC): National Toxicology Program; 2013 Oct.

Cover of NTP Genetically Modified Model Report on the Toxicology and Carcinogenicity Studies of 3’-Azido-3’-Deoxythymidine (CASRN 30516-87-1) in Genetically Modified C3B6.129F1-Trp53tm1Brd N12 Haploinsufficient Mice (In Utero and Postnatal Gavage Study)

NTP Genetically Modified Model Report on the Toxicology and Carcinogenicity Studies of 3’-Azido-3’-Deoxythymidine (CASRN 30516-87-1) in Genetically Modified C3B6.129F1-Trp53^tm1Brd N12 Haploinsufficient Mice (In Utero and Postnatal Gavage Study): NTP GMM 14 [Internet].

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APPENDIX IHISTORICAL CONTROL INCIDENCES

Table I1. Historical Incidences of Neoplasms in Control Male Heterozygous F1 p53^+/− Mice in the 30- and 45-Week NCTR Studies of AZT, the 45-Week NCTR Study of AZT/3TC/NVP, and the 40-Week NTP Study of Senna

Table I2. Historical Incidences of Neoplasms in Control Female Heterozygous F1 p53^+/− Mice in the 30- and 45-Week NCTR Studies of AZT, the 45-Week NCTR Study of AZT/3TC/NVP, and the 40-Week NTP Study of Senna

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Leakey JEA, Allaben WT, Dunnick JK, et al. NTP Genetically Modified Model Report on the Toxicology and Carcinogenicity Studies of 3’-Azido-3’-Deoxythymidine (CASRN 30516-87-1) in Genetically Modified C3B6.129F1-Trp53tm1Brd N12 Haploinsufficient Mice (In Utero and Postnatal Gavage Study): NTP GMM 14 [Internet]. Research Triangle Park (NC): National Toxicology Program; 2013 Oct. APPENDIX I, HISTORICAL CONTROL INCIDENCES.
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NTP Genetically Modified Model Report on the Toxicology and Carcinogenicity Studies of 3’-Azido-3’-Deoxythymidine (CASRN 30516-87-1) in Genetically Modified C3B6.129F1-Trp53tm1Brd N12 Haploinsufficient Mice (In Utero and Postnatal Gavage Study): NTP GMM 14 [Internet].

APPENDIX IHISTORICAL CONTROL INCIDENCES

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NTP Genetically Modified Model Report on the Toxicology and Carcinogenicity Studies of 3’-Azido-3’-Deoxythymidine (CASRN 30516-87-1) in Genetically Modified C3B6.129F1-Trp53^tm1Brd N12 Haploinsufficient Mice (In Utero and Postnatal Gavage Study): NTP GMM 14 [Internet].