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Cover of Evidence review for effectiveness of multidisciplinary teams for the assessment and management of urinary incontinence or pelvic organ prolapse

Evidence review for effectiveness of multidisciplinary teams for the assessment and management of urinary incontinence or pelvic organ prolapse

Urinary incontinence and pelvic organ prolapse in women: management

Evidence review F

NICE Guideline, No. 123

.

London: National Institute for Health and Care Excellence (NICE); .
ISBN-13: 978-1-4731-3319-8

Effectiveness of multidisciplinary teams for the assessment and management of urinary incontinence or pelvic organ prolapse

Review question

What is the effectiveness of multidisciplinary teams (MDTs) of various compositions for the assessment and management of simple and complex cases of urinary incontinence (UI) or pelvic organ prolapse (POP), including mesh complications?

Introduction

At present, there is no evidence in the literature regarding the use of MDTs in urogynaecology (Balachandran & Duckett 2015). UI and POP are often complex and can co-exist in a considerable proportion of women. In addition, the surgical management of UI or POP can lead to complex complications including mesh complications. Therefore, women with these problems may benefit from a MDT assessment and management approach.

This review will examine the effectiveness of multidisciplinary teams for the assessment and management of simple and complex cases of urinary incontinence (UI) or pelvic organ prolapse (POP), including mesh complications.

Summary of the protocol

Please see Table 1 for a summary of the Population, Intervention, Comparison and Outcome (PICO) characteristics of this review.

Table 1. Summary of the protocol (PICO table).

Table 1

Summary of the protocol (PICO table).

For further details see the review protocol in appendix A.

Methods and process

This evidence review was developed using the methods and process described in Developing NICE guidelines: the manual 2014. Methods specific to this review question are described in the review protocol in appendix A and for a full description of the methods see supplementary material C.

Declarations of interest were recorded according to NICE’s 2014 conflicts of interest policy until 31 March 2018. From 1 April 2018, declarations of interest were recorded according to NICE’s 2018 conflicts of interest policy. Those interests declared until April 2018 were reclassified according to NICE’s 2018 conflicts of interest policy (see Register of Interests).

Clinical evidence

Included studies

A systematic review of the clinical literature was conducted but no studies were found which were applicable to this review question.

See the literature search strategy in appendix B and the study selection flow chart in appendix C.

Excluded studies

Studies not included in this review with reasons for their exclusions are provided in appendix K.

Summary of clinical studies included in the evidence review

No studies were found which were applicable to this review question.

Quality assessment of clinical studies included in the evidence review

No studies were found which were applicable to this review question.

Economic evidence

Included studies

A systematic review of the economic literature was conducted but no studies were identified which were applicable to this review question. See supplementary material D for further information.

Excluded studies

No studies were found which were applicable to this review question.

Summary of studies included in the economic evidence review

No economic evaluations were identified which were applicable to this review question.

Economic model

No economic modelling was undertaken for this review because the committee expected that there would be no clinical evidence to inform an economic evaluation and also agreed that other topics were higher priorities.

Clinical evidence statements

No studies were found which were applicable to this review question.

Economic evidence statements

No studies were found which were applicable to this review question.

The committee’s discussion of the evidence

Interpreting the evidence
The outcomes that matter most

The Committee decided that ‘change in management decisions’ and ‘health-related quality of life’ (specific to urinary incontinence or pelvic organ prolapse) were critical outcomes. Patient satisfaction was considered an important outcome.

The quality of the evidence

No clinical evidence on effectiveness of multidisciplinary teams for the assessment and management of urinary incontinence or pelvic organ prolapse, including mesh complications was found for this review.

Benefits and harms

In the absence of evidence the committee made all recommendations relevant to this evidence review based on their expertise and experience and by consensus. They agreed that it was important to make these recommendations because women with UI often have complex coexisting conditions such as POP and bowel symptoms, and therefore may benefit from a MDT assessment and management approach. In addition, women with mesh complications after UI and/or POP surgery using mesh may present with a variety of symptoms and management of these women may be complex. The decision on how to treat these women requires a team of expert health professionals within a region to ensure that all suitable options have been considered and offered.

The committee discussed the importance of outlining what an MDT is and setting out the composition of the various MDT teams. There is currently no definition of what comprises an effective MDT for the assessment and management of simple and complex cases of UI or POP, including mesh complications. Also there is currently no evidence to suggest when simple and/or complex UI or POP cases, including mesh complications, should be referred to an MDT. The committee decided that women with these complex conditions require more specialised care and input from a wider specialist team and they also agreed the different levels of MDT involvement. The committee agreed on two levels of MDT:

  • Local (for women with primary SUI, OAB or primary prolapse);
  • Regional (for women with recurrent UI and/or POP surgery, for those who require surgery that is not available locally or for those with complex pelvic floor dysfunction and mesh related problems).

The committee noted that some interventions may be offered for UI and/or POP which are not available locally. If local MDTs work within a regional clinical network with a regional MDT, women can be referred elsewhere in that network for treatment. Women with mesh complications may benefit from a MDT approach to future care planning.

The committee noted that it might be difficult to state exactly who should be in an MDT, as this will not only depend on the condition (UI or POP) but also on the resources available at local and regional levels. The committee wanted to be clear that more than one consultant with expertise in the management of urinary incontinence and pelvic organ prolapse are needed to ensure that full discussion of care takes place. The committee wish to remove the risk of one individual making decisions without full consideration from other specialists with similar knowledge. The committee also agreed that Occupational therapists would not be needed as core members of the MTDT. Pelvic floor physiotherapy is directly involved in primary treatment of urinary incontinence and prolapse, and occupational therapists are there to advise on patients with co-morbidities who may have other considerations to take into account. As there are fewer women in this latter group, an occupational therapists would not be needed as a core member of the MDT.

The committee agreed that the recommendation on local MDT composition reflects the current arrangements throughout England and Wales because different trusts have different availability of MDT members.. They also noted that there may be circumstances in which continence services are provided by urologists rather than urogynaecologists and therefore the local MDT needs to reflect local arrangements. They agreed that all members of the local MDT should attend all local MDT meetings. They agreed that the regional teams are more likely to include more specialist members. The specific composition of the regional MDT meetings may vary depending on required expertise and case mix and therefore, and the committee noted that for regional MDTs members should attend when their specific expertise is needed.

When drafting the recommendations for this guideline, the committee highlighted the potential overlap with the recommendations in the commissioning review (NHS England’s Complex Gynaecology Specialised Commissioning Team - https://www.engage.england.nhs.uk/consultation/gynaecology-surgery-and-complex-urogynecology/). The committee agreed that at a minimum, these two levels of MDT (local and regional) are required; however, the committee discussed the possibility of three levels of care, with a third level specialising in the care for women with complex pelvic floor dysfunction and mesh related complications (Supra regional). The committee are aware of the current NHS England consultation on specialised gynaecology surgery and complex urogynaecology conditions service specifications, which was launched in August 2018, and runs until November 2018. The committee are clear that women with complex pelvic floor dysfunction and mesh related complications require expert clinical teams at specialist centres, but the final distribution and definition of these centres may change after this NHS consultation period.

Cost effectiveness and resource use

There was no evidence on the cost effectiveness of multidisciplinary teams for the assessment and management of urinary incontinence or pelvic organ prolapse, including mesh complications.

The committee thought that women with mesh complications appear to be badly served by the current service configuration and that delays and inappropriate treatment may make symptoms that may need expensive secondary care management worse. The committee expressed the view that, in principle, if specialist mesh service MDTs improve their assessment and monitoring and this leads to the timely identification and appropriate treatment of mesh complications, then the additional costs associated with such a service configuration would probably be outweighed by the longer term improvements in health outcomes and the potential future cost savings to the healthcare system,.

The committee also noted that increasingly women cannot obtain care they want locally. For example, women who do not want the procedure they are offered locally (e.g. TVT), may need to be referred to another centre where they can have procedure they would prefer.

The committee discussed the benefits of different compositions of MDT services and agreed that having a tiered approach to MDTs (i.e. local, and regional, service MDTs) may result in substantial savings to the NHS. For example, the MDT would not require every single specialist (e.g. pain specialist, colorectal surgeon or neurologist) for every with prolapse being discussed. By more closely defining the composition of the various MDTs (e.g. only regional MDTs would need to include pain specialists) scarce and expensive consultant time might be freed up. Given the large number of procedures undertaken, such a tiered approach could result in a significant overall cost saving to the NHS.

Other factors the committee took into account

The committee discussed the implications of these recommendations on resources and job planning. The committee noted the current lack of resources for MDT reviews which may limit implementation of these recommendations.

The committee also noted that the new recommendations should make it easier for MDTs to meet regularly.

References

  • Balachandran 2015

    Balachandran A, Duckett J. What is the role of the multidisciplinary team in the management of urinary incontinence? Int Urogynecol J. 26, 791–3 2015 [PubMed: 25416023]

Appendices

Appendix A. Review protocols

Review protocol for review question: What is the effectiveness of MDTs for the assessment and management of UI or POP, including mesh complications?

Table 2. Review protocol for effectiveness of MDTs for assessment and management of UI or POP, including mesh complications

Appendix B. Literature search strategies

Literature search strategies for review question: What is the effectiveness of MDTs for the assessment and management of UI or POP, including mesh complications?

Database: Medline & Embase (Multifile)

Last searched on Embase Classic+Embase 1947 to 2017 July 19, Ovid MEDLINE(R) Epub Ahead of Print, In-Process & Other Non-Indexed Citations, Ovid MEDLINE(R) Daily and Ovid MEDLINE(R) 1946 to Present.

Date of last search: 20th July 2017

Database: Cochrane Library via Wiley Online

Date of last search: 20th July 2017

Additional Grey Literature searching

Date of last search: 31st July 2017.

Search terms: MDT terms AND (Urinary Incontinence or Prolapse)

Sources searched: NHS Evidence, Google and the following organisations websitesa:

  • British Association of Urological Surgeons (BAUS)
  • British Association of Urological Nurses (BAUN)
  • United Kingdom Continence Society (UKCS)
  • British Society of Urogynaecologists (BSUG)
  • International Continence Society (ICS) conference abstracts
  • International Urogynecological Association (IUGA) conference abstracts

Appendix C. Clinical evidence study selection

Clinical evidence study selection for review question: What is the effectiveness of MDTs for the assessment and management of UI or POP, including mesh complications?

Figure 1. PRISMA flow chart for effectiveness of MDTs for the assessment and management of UP or POP

Appendix D. Clinical evidence tables

Clinical evidence tables for review question: What is the effectiveness of MDTs for the assessment and management of UI or POP, including mesh complications?

No studies were identified which were applicable to this review question.

Appendix E. Forest plots

Forest plots for review question: What is the effectiveness of MDTs for the assessment and management of UI or POP, including mesh complications?

No studies were identified which were applicable to this review question.

Appendix F. GRADE tables

GRADE tables for review question: What is the effectiveness of MDTs for the assessment and management of UI or POP, including mesh complications?

No studies were identified which were applicable to this review question.

Appendix G. Economic evidence study selection

Economic evidence study selection for review question: What is the effectiveness of MDTs for the assessment and management of UI or POP, including mesh complications?

No economic studies were identified for this review question.

Appendix H. Economic evidence tables

Economic evidence tables for review question: What is the effectiveness of MDTs for the assessment and management of UI or POP, including mesh complications?

No economic studies were identified for this review question.

Appendix I. Economic evidence profiles

Economic evidence profiles for review question: What is the effectiveness of MDTs for the assessment and management of urinary incontinence or pelvic organ prolapse, including mesh complications?

No economic studies were identified for this review question.

Appendix J. Economic analysis

Economic evidence analysis for review question: What is the effectiveness of MDTs for the assessment and management of urinary incontinence or pelvic organ prolapse, including mesh complications?

No economic studies were identified for this review question.

Appendix K. Excluded studies

Excluded studies for review question: What is the effectiveness of MDTs for the assessment and management of UI or POP, including mesh complications?

Economic studies

No economic studies were identified for this review question. See supplementary material D for further information.

Appendix L. Research recommendations

Research recommendations for review question: What is the effectiveness of MDTs for the assessment and management of UI or POP, including mesh complications?

No research recommendation was made for this review question.

Footnotes

a

Organisations highlighted in Review Protocol discussion with GC on 18th July 2017.

Final

Evidence reviews

These evidence reviews were developed by the National Guideline Alliance hosted by the Royal College of Obstetricians and Gynaecologists

Disclaimer: The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or service users. The recommendations in this guideline are not mandatory and the guideline does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or their carer or guardian.

Local commissioners and/or providers have a responsibility to enable the guideline to be applied when individual health professionals and their patients or service users wish to use it. They should do so in the context of local and national priorities for funding and developing services, and in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Nothing in this guideline should be interpreted in a way that would be inconsistent with compliance with those duties.

NICE guidelines cover health and care in England. Decisions on how they apply in other UK countries are made by ministers in the Welsh Government, Scottish Government, and Northern Ireland Executive. All NICE guidance is subject to regular review and may be updated or withdrawn.

Copyright © NICE 2019.
Bookshelf ID: NBK577748PMID: 35138779

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