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National Collaborating Centre for Mental Health (UK). Antenatal and Postnatal Mental Health: Clinical Management and Service Guidance: Updated edition. Leicester (UK): British Psychological Society; 2014 Dec. (NICE Clinical Guidelines, No. 192.)

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  • April 2018: Footnotes and cautions have been added and amended by NICE to link to the MHRA's latest advice and resources on sodium valproate. Sodium valproate must not be used in pregnancy, and only used in girls and women when there is no alternative and a pregnancy prevention plan is in place. This is because of the risk of malformations and developmental abnormalities in the baby.

April 2018: Footnotes and cautions have been added and amended by NICE to link to the MHRA's latest advice and resources on sodium valproate. Sodium valproate must not be used in pregnancy, and only used in girls and women when there is no alternative and a pregnancy prevention plan is in place. This is because of the risk of malformations and developmental abnormalities in the baby.

Cover of Antenatal and Postnatal Mental Health

Antenatal and Postnatal Mental Health: Clinical Management and Service Guidance: Updated edition.

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APPENDIX 22CLINICAL AND ECONOMIC EVIDENCE PROFILES

1. CLINICAL EVIDENCE PROFILES

1.1. PSYCHOSOCIAL INTERVENTIONS: PREVENTION (RISK FACTORS IDENTIFIED)

1.1.1. Depression: post-miscarriage self-help versus TAU (PDF, 230K)

1.1.2. Depression: social support versus TAU (PDF, 240K)

1.1.3. Depression: psychologically (CBT/IPT)-informed psychoeducation versus TAU or enhanced TAU (PDF, 272K)

1.1.4. Depression: psychoeducational booklet versus TAU or enhanced TAU (PDF, 253K)

1.1.5. Depression: non-mental health-focused education and support versus TAU or enhanced TAU (PDF, 284K)

1.1.6. Depression: home visits versus TAU (PDF, 255K)

1.1.7. Depression: post-delivery discussion versus enhanced TAU (PDF, 257K)

1.1.8. Depression: mother–infant relationship interventions versus TAU (PDF, 273K)

1.1.9. Depression: case management and individualised treatment (PDF, 239K)

1.1.10. Anxiety: post-miscarriage self-help versus TAU (PDF, 236K)

1.1.11. Anxiety: non-mental health-focused education and support versus TAU or enhanced TAU (PDF, 266K)

1.1.12. Anxiety: home visits versus TAU (PDF, 254K)

1.1.13. PTSD: post-miscarriage self-help versus TAU (PDF, 239K)

1.1.14. General mental health: post-miscarriage self-help versus TAU (PDF, 231K)

1.1.15. General mental health: home visits versus TAU (PDF, 307K)

1.1.16. General mental health: post-delivery discussion versus enhanced TAU (PDF, 314K)

1.1.17. General mental health: mother–infant relationship interventions versus TAU (PDF, 314K)

1.1.18. Mother–infant attachment: non-mental health-focused education and support versus TAU or enhanced TAU (PDF, 266K)

1.1.19. Mother–infant attachment: home visits versus TAU (PDF, 242K)

1.1.20. Mother–infant attachment: mother–infant relationship interventions versus TAU (PDF, 363K)

1.1.21. Mother–infant attachment: case management and individualised treatment (PDF, 241K)

1.1.22. Quality of life: psychologically (CBT/IPT)-informed psychoeducation versus TAU or enhanced TAU (PDF, 316K)

1.1.23. Quality of life: non-mental health-focused education and support versus TAU or enhanced TAU (PDF, 322K)

1.1.24. Quality of life: home visits versus TAU (PDF, 384K)

1.1.25. Quality of life: mother–infant relationship interventions versus TAU (PDF, 310K)

1.1.26. Quality of life: case management and individualised treatment versus TAU (PDF, 248K)

1.1.27. Service utilisation: psychologically (CBT/IPT)-informed psychoeducation versus TAU or enhanced TAU (PDF, 241K)

1.1.28. Service utilisation: home visits versus TAU (PDF, 320K)

1.1.29. Experience of care: non-mental health-focused education and support versus TAU or enhanced TAU (PDF, 312K)

1.1.30. Attrition: post-miscarriage self-help versus TAU (PDF, 232K)

1.1.31. Attrition: social support versus TAU (PDF, 237K)

1.1.32. Attrition: psychologically (CBT/IPT)-informed psychoeducation versus TAU or enhanced TAU (PDF, 307K)

1.1.33. Attrition: psychoeducational booklet versus TAU or enhanced TAU (PDF, 307K)

1.1.34. Attrition: non-mental health-focused education and support versus TAU or enhanced TAU (PDF, 388K)

1.1.35. Attrition: home visits versus TAU (PDF, 381K)

1.1.36. Attrition: post-delivery discussion versus enhanced TAU (PDF, 307K)

1.1.37. Attrition: mother–infant relationship interventions versus TAU (PDF, 314K)

1.1.38. Infant physical health: home visits versus TAU (PDF, 403K)

1.1.39. Infant regulatory problems: mother–infant relationship interventions versus TAU (PDF, 327K)

1.1.40. Infant physical development: home visits versus TAU (PDF, 255K)

1.1.41. Infant cognitive development: home visits versus TAU (PDF, 377K)

1.1.42. Infant emotional development: home visits versus TAU (PDF, 471K)

1.1.43. Infant emotional development: mother–infant relationship interventions versus TAU (PDF, 245K)

1.1.44. Prevention of neglect or abuse of the infant: home visits versus TAU (PDF, 319K)

1.2. PSYCHOSOCIAL INTERVENTIONS: PREVENTION (NO RISK FACTORS IDENTIFIED)

1.2.1. Depression: structured psychological interventions (CBT or IPT) versus TAU (PDF, 127K)

1.2.2. Depression: listening visits versus TAU (PDF, 125K)

1.2.3. Depression: psychologically (CBT/IPT)-informed psychoeducation versus enhanced TAU (PDF, 142K)

1.2.4. Depression: home visits versus TAU (PDF, 121K)

1.2.5. Depression: post-delivery discussion versus TAU (PDF, 120K)

1.2.6. Depression: mother–infant relationship interventions versus enhanced TAU (PDF, 127K)

1.2.7. Depression: mindfulness training versus TAU (PDF, 120K)

1.2.8. Anxiety: structured psychological interventions (CBT or IPT) versus TAU (PDF, 122K)

1.2.9. Anxiety: listening visits versus TAU (PDF, 127K)

1.2.10. Anxiety: post-delivery discussion versus TAU (PDF, 120K)

1.2.11. Anxiety: music therapy versus TAU (PDF, 121K)

1.2.12. Anxiety: mindfulness training versus TAU (PDF, 120K)

1.2.13. General mental health: structured psychological interventions (CBT or IPT) versus TAU (PDF, 234K)

1.2.14. General mental health: listening visits versus TAU (PDF, 314K)

1.2.15. General mental health: home visits versus TAU (PDF, 314K)

1.2.16. General mental health: mindfulness training versus TAU (PDF, 317K)

1.2.17. Mother–infant attachment: home visits versus TAU (PDF, 389K)

1.2.18. Mother–infant attachment: mother–infant relationship interventions versus enhanced TAU (PDF, 401K)

1.2.19. Mother–infant attachment: mindfulness training versus TAU (PDF, 236K)

1.2.20. Quality of life: structured psychological interventions (CBT or IPT) versus TAU (PDF, 240K)

1.2.21. Quality of life: listening visits versus TAU (PDF, 392K)

1.2.22. Quality of life: home visits versus TAU (PDF, 389K)

1.2.23. Quality of life: mother–infant relationship interventions versus enhanced TAU (PDF, 315K)

1.2.24. Quality of life: music therapy versus TAU (PDF, 307K)

1.2.25. Quality of life: mindfulness training versus TAU (PDF, 236K)

1.2.26. Attrition: structured psychological interventions (CBT or IPT) versus TAU (PDF, 306K)

1.2.27. Attrition: listening visits versus TAU (PDF, 381K)

1.2.28. Attrition: psychologically (CBT/IPT)-informed psychoeducation versus enhanced TAU (PDF, 313K)

1.2.29. Attrition: home visits versus TAU (PDF, 307K)

1.2.30. Attrition: mindfulness training versus TAU (PDF, 312K)

1.3. PSYCHOSOCIAL INTERVENTIONS: TREATMENT

1.3.1. Depression: structured psychological interventions (CBT or IPT) versus TAU or enhanced TAU (PDF, 192K)

1.3.2. Depression: CBT versus listening visits (PDF, 124K)

1.3.3. Depression: CBT versus relational constructivist therapy (PDF, 146K)

1.3.4. Depression: IPT versus support group (PDF, 126K)

1.3.5. Depression: facilitated self-help versus TAU (PDF, 129K)

1.3.6. Depression: post-miscarriage self-help versus TAU (PDF, 130K)

1.3.7. Depression: post-miscarriage facilitated self-help versus TAU (PDF, 126K)

1.3.8. Depression: listening visits versus TAU (PDF, 167K)

1.3.9. Depression: directive counselling versus TAU (PDF, 133K)

1.3.10. Depression: post-miscarriage counselling versus TAU (PDF, 132K)

1.3.11. Depression: post-traumatic birth counselling versus TAU (PDF, 126K)

1.3.12. Depression: social support versus TAU (PDF, 143K)

1.3.13. Depression: psychologically (CBT/IPT)-informed psychoeducation versus TAU or enhanced TAU (PDF, 169K)

1.3.14. Depression: IPT-informed psychoeducation versus non-mental health-focused education and support (PDF, 125K)

1.3.15. Depression: non-mental health-focused education and support versus TAU (PDF, 128K)

1.3.16. Depression: home visits versus TAU or enhanced TAU (PDF, 133K)

1.3.17. Depression: mother–infant relationship interventions versus TAU or enhanced TAU (PDF, 166K)

1.3.18. Depression: mother–infant relationship intervention with video feedback versus mother–infant relationship intervention with verbal feedback (PDF, 125K)

1.3.19. Depression: co-parenting intervention versus enhanced TAU (PDF, 129K)

1.3.20. Depression: infant sleep training (controlled crying) versus TAU or enhanced TAU (PDF, 130K)

1.3.21. Depression: music therapy during birth versus TAU (PDF, 130K)

1.3.22. Depression: psychosomatic intervention versus TAU (PDF, 129K)

1.3.23. Depression: mindfulness training versus enhanced TAU (PDF, 127K)

1.3.24. Anxiety: structured psychological interventions versus TAU or enhanced TAU (PDF, 128K)

1.3.25. Anxiety: CBT versus relational constructivist therapy (PDF, 146K)

1.3.26. Anxiety: IPT versus support group (PDF, 121K)

1.3.27. Anxiety: facilitated self-help versus TAU (PDF, 130K)

1.3.28. Anxiety: post-miscarriage self-help versus TAU (PDF, 128K)

1.3.29. Anxiety: listening visits versus TAU (PDF, 126K)

1.3.30. Anxiety: directive counselling versus TAU (PDF, 148K)

1.3.31. Anxiety: post-miscarriage counselling versus enhanced TAU (PDF, 123K)

1.3.32. Anxiety: post-traumatic birth counselling versus TAU (PDF, 128K)

1.3.33. Anxiety: social support versus TAU (PDF, 130K)

1.3.34. Anxiety: psychologically (CBT/IPT)-informed psychoeducation versus TAU or enhanced TAU (PDF, 133K)

1.3.35. Anxiety: mother–infant relationship interventions versus TAU or enhanced TAU (PDF, 132K)

1.3.36. Anxiety: music therapy during birth versus TAU (PDF, 120K)

1.3.37. Anxiety: psychosomatic intervention versus TAU (PDF, 126K)

1.3.38. Anxiety: mindfulness training versus enhanced TAU (PDF, 122K)

1.3.39. Adjustment disorder: psychologically (CBT/IPT)-informed psychoeducation versus TAU or enhanced TAU (PDF, 123K)

1.3.40. PTSD: post-miscarriage self-help versus TAU (PDF, 124K)

1.3.41. PTSD: post-traumatic birth counselling versus TAU (PDF, 132K)

1.3.42. PTSD: psychologically (CBT/IPT)-informed psychoeducation versus TAU or enhanced TAU (PDF, 130K)

1.3.43. PTSD: mother–infant relationship interventions versus TAU or enhanced TAU (PDF, 139K)

1.3.44. OCD: psychologically (CBT/IPT)-informed psychoeducation versus TAU or enhanced TAU (PDF, 143K)

1.3.45. Fear of childbirth: pre-delivery discussion/psychoeducation versus TAU (PDF, 149K)

1.3.46. Eating disorder: mother–infant relationship interventions (and guided self-help) versus listening visits (and guided self-help) (PDF, 128K)

1.3.47. General mental health: structured psychological interventions (CBT or IPT) versus TAU or enhanced TAU (PDF, 133K)

1.3.48. General mental health: IPT versus support group (PDF, 125K)

1.3.49. General mental health: post-miscarriage self-help versus TAU (PDF, 130K)

1.3.50. General mental health: listening visits versus TAU (PDF, 122K)

1.3.51. General mental health: post-miscarriage counselling versus TAU (PDF, 122K)

1.3.52. General mental health: post-traumatic birth counselling versus TAU (PDF, 127K)

1.3.53. General mental health: psychologically (CBT/IPT)-informed psychoeducation versus TAU or enhanced TAU (PDF, 132K)

1.3.54. General mental health: home visits versus TAU/enhanced TAU (PDF, 133K)

1.3.55. General mental health: mother–infant relationship interventions versus TAU or enhanced TAU (PDF, 130K)

1.3.56. General mental health: co-parenting intervention versus enhanced TAU (PDF, 120K)

1.3.57. Mother–infant attachment: structured psychological interventions (CBT or IPT) versus TAU or enhanced TAU (PDF, 158K)

1.3.58. Mother–infant attachment: facilitated self-help versus TAU (PDF, 120K)

1.3.59. Mother–infant attachment: listening visits versus TAU (PDF, 145K)

1.3.60. Mother–infant attachment: social support versus TAU (PDF, 127K)

1.3.61. Mother–infant attachment: psychologically (CBT/IPT)-informed psychoeducation versus enhanced TAU (PDF, 122K)

1.3.62. Mother–infant attachment: home visits versus TAU or enhanced TAU (PDF, 123K)

1.3.63. Mother–infant attachment: mother–infant relationship interventions versus TAU or enhanced TAU (PDF, 223K)

1.3.64. Mother–infant attachment: mother–infant relationship intervention with video feedback versus mother–infant relationship intervention with verbal feedback (PDF, 126K)

1.3.65. Mother–infant attachment: mother–infant relationship intervention (and guided self-help) versus listening visits (and guided self-help) (PDF, 146K)

1.3.66. Quality of life: structured psychological interventions (CBT or IPT) versus TAU/enhanced TAU (PDF, 339K)

1.3.67. Quality of life: IPT versus support group (PDF, 311K)

1.3.68. Quality of life: facilitated self-help versus TAU (PDF, 319K)

1.3.69. Quality of life: listening visits versus TAU (PDF, 321K)

1.3.70. Quality of life: directive counselling versus TAU (PDF, 306K)

1.3.71. Quality of life: post-miscarriage counselling versus TAU (PDF, 235K)

1.3.72. Quality of life: post-traumatic birth counselling versus TAU (PDF, 238K)

1.3.73. Quality of life: social support versus TAU (PDF, 325K)

1.3.74. Quality of life: psychologically (CBT/IPT)-informed psychoeducation versus TAU/enhanced TAU (PDF, 353K)

1.3.75. Quality of life: home visits versus TAU/enhanced TAU (PDF, 318K)

1.3.76. Quality of life: mother–infant relationship interventions versus TAU/enhanced TAU (PDF, 317K)

1.3.77. Quality of life: psychosomatic intervention versus TAU (PDF, 234K)

1.3.78. Quality of life: mindfulness training versus TAU/enhanced TAU (PDF, 319K)

1.3.79. Service utilisation: structured psychological interventions (CBT or IPT) versus TAU/enhanced TAU (PDF, 353K)

1.3.80. Service utilisation: facilitated self-help versus TAU (PDF, 370K)

1.3.81. Service utilisation: listening visits versus TAU (PDF, 345K)

1.3.82. Service utilisation: social support versus TAU (PDF, 330K)

1.3.83. Experience of care: mother–infant relationship interventions versus TAU/enhanced TAU (PDF, 309K)

1.3.84. Attrition: structured psychological interventions (CBT or IPT) versus TAU/enhanced TAU (PDF, 308K)

1.3.85. Attrition: CBT versus relational constructivist therapy (PDF, 237K)

1.3.86. Attrition: IPT versus support group (PDF, 409K)

1.3.87. Attrition: facilitated self-help versus TAU (PDF, 385K)

1.3.88. Attrition: listening visits versus TAU (PDF, 306K)

1.3.89. Attrition: directive counselling versus TAU (PDF, 232K)

1.3.90. Attrition: post-miscarriage counselling versus TAU/enhanced TAU (PDF, 313K)

1.3.91. Attrition: post-traumatic birth counselling versus TAU (PDF, 277K)

1.3.92. Attrition: social support versus TAU (PDF, 313K)

1.3.93. Attrition: psychologically (CBT/IPT)-informed psychoeducation versus TAU/enhanced TAU (PDF, 307K)

1.3.94. Attrition: non-mental health-focused education and support versus TAU (PDF, 307K)

1.3.95. Attrition: home visits versus TAU (PDF, 237K)

1.3.96. Attrition: mother–infant relationship interventions versus TAU/enhanced TAU (PDF, 307K)

1.3.97. Attrition: mother–infant relationship intervention with video feedback versus mother–infant relationship intervention with verbal feedback (PDF, 383K)

1.3.98. Attrition: mother–infant relationship intervention (and guided self-help) versus listening visits (and guided self-help) (PDF, 314K)

1.3.99. Attrition: co-parenting intervention versus enhanced TAU (PDF, 202K)

1.3.100. Attrition: music therapy during birth versus TAU (PDF, 388K)

1.3.101. Attrition: psychosomatic intervention versus TAU (PDF, 312K)

1.3.102. Attrition: mindfulness training versus enhanced TAU (PDF, 307K)

1.3.103. Infant service use: facilitated self-help versus TAU (PDF, 321K)

1.3.104. Infant service use: listening visits versus TAU (PDF, 403K)

1.3.105. Infant service use: home visits versus TAU (PDF, 328K)

1.3.106. Infant service use: mother–infant relationship interventions versus TAU/enhanced TAU (PDF, 354K)

1.3.107. Infant physical health: structured psychological interventions (CBT or IPT) versus TAU/enhanced TAU (PDF, 352K)

1.3.108. Infant physical health: IPT versus support group (PDF, 314K)

1.3.109. Infant physical health: listening visits versus TAU (PDF, 315K)

1.3.110. Infant physical health: social support versus TAU (PDF, 306K)

1.3.111. Infant physical health: psychologically (CBT/IPT)-informed psychoeducation versus TAU/enhanced TAU (PDF, 317K)

1.3.112. Infant physical health: mother–infant relationship intervention (and guided self-help) versus listening visits (and guided self-help) (PDF, 325K)

1.3.113. Infant physical development: CBT versus listening visits (PDF, 232K)

1.3.114. Infant physical development: listening visits versus TAU (PDF, 325K)

1.3.115. Infant physical development: home visits versus TAU (PDF, 322K)

1.3.116. Infant physical development: mother–infant relationship interventions versus TAU/enhanced TAU (PDF, 307K)

1.3.117. Infant physical development: infant sleep training (controlled crying) versus TAU (PDF, 321K)

1.3.118. Infant cognitive development: CBT versus listening visits (PDF, 307K)

1.3.119. Infant cognitive development: listening visits versus TAU (PDF, 400K)

1.3.120. Infant cognitive development: social support versus TAU (PDF, 312K)

1.3.121. Infant cognitive development: home visits versus TAU (PDF, 240K)

1.3.122. Infant cognitive development: mother–infant relationship interventions versus TAU/enhanced TAU (PDF, 315K)

1.3.123. Infant emotional development: social support versus TAU (PDF, 382K)

1.3.124. Infant emotional development: home visits versus TAU (PDF, 335K)

1.3.125. Infant emotional development: mother–infant relationship interventions versus TAU/enhanced TAU (PDF, 338K)

1.3.126. Infant emotional development: infant sleep training (controlled crying) versus TAU (PDF, 313K)

1.3.127. Prevention of neglect or abuse of the infant: listening visits versus TAU (PDF, 325K)

1.3.128. Prevention of neglect or abuse of the infant: home visits versus TAU (PDF, 349K)

1.3.129. Optimal infant care: structured psychological interventions (CBT or IPT) versus TAU/enhanced TAU (PDF, 293K)

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