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National Collaborating Centre for Mental Health (UK). Bipolar Disorder: The NICE Guideline on the Assessment and Management of Bipolar Disorder in Adults, Children and Young People in Primary and Secondary Care. London: The British Psychological Society and The Royal College of Psychiatrists; 2014 Sep. (NICE Clinical Guidelines, No. 185.)

  • April 2018: Footnotes and cautions have been added and amended to link to the MHRA's latest advice and resources on sodium valproate. Sodium valproate must not be used in pregnancy, and only used in girls and women when there is no alternative and a pregnancy prevention plan is in place. This is because of the risk of malformations and developmental abnormalities in the baby. November 2017: Footnotes for some recommendations were updated with current UK marketing authorisations and MHRA advice. Links to other guidelines have also been updated. Some research recommendations have been stood down. See these changes in the short version of the guideline.

April 2018: Footnotes and cautions have been added and amended to link to the MHRA's latest advice and resources on sodium valproate. Sodium valproate must not be used in pregnancy, and only used in girls and women when there is no alternative and a pregnancy prevention plan is in place. This is because of the risk of malformations and developmental abnormalities in the baby. November 2017: Footnotes for some recommendations were updated with current UK marketing authorisations and MHRA advice. Links to other guidelines have also been updated. Some research recommendations have been stood down. See these changes in the short version of the guideline.

Cover of Bipolar Disorder

Bipolar Disorder: The NICE Guideline on the Assessment and Management of Bipolar Disorder in Adults, Children and Young People in Primary and Secondary Care.

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APPENDIX 2Declarations of Interests by Guideline Development Group Members

With a range of practical experience relevant to bipolar disorder in the GDG, members were appointed because of their understanding and expertise in healthcare for people with bipolar disorder and support for their families/carers, including: scientific issues; health research; the delivery and receipt of healthcare, along with the work of the healthcare industry; and the role of professional organisations and organisations for people with bipolar disorder and their families/carers.

To minimise and manage any potential conflicts of interest, and to avoid any public concern that commercial or other financial interests have affected the work of the GDG and influenced guidance, members of the GDG must declare as a matter of public record any interests held by themselves or their families which fall under specified categories (see below). These categories include any relationships they have with the healthcare industries, professional organisations and organisations for people with bipolar disorder and their families/carers.

Individuals invited to join the GDG were asked to declare their interests before being appointed. To allow the management of any potential conflicts of interest that might arise during the development of the guideline, GDG members were also asked to declare their interests at each GDG meeting throughout the guideline development process. The interests of all the members of the GDG are listed below, including interests declared prior to appointment and during the guideline development process.

Categories of interest to be written in third person

Paid employment

Personal pecuniary interest: financial payments or other benefits from either the manufacturer or the owner of the product or service under consideration in this guideline, or the industry or sector from which the product or service comes. This includes holding a directorship or other paid position; carrying out consultancy or fee paid work; having shareholdings or other beneficial interests; receiving expenses and hospitality over and above what would be reasonably expected to attend meetings and conferences.

Personal family interest: financial payments or other benefits from the healthcare industry that were received by a member of your family.

Non-personal pecuniary interest: financial payments or other benefits received by the GDG member’s organisation or department, but where the GDG member has not personally received payment, including fellowships and other support provided by the healthcare industry. This includes a grant or fellowship or other payment to sponsor a post, or contribute to the running costs of the department; commissioning of research or other work; contracts with, or grants from, NICE.

Personal non-pecuniary interest: these include, but are not limited to, clear opinions or public statements you have made about individuals with bipolar disorder, holding office in a professional organisation or advocacy group with a direct interest in bipolar disorder, other reputational risks relevant to bipolar disorder.

GDG – declarations of interest
Richard Morriss
Employment

Professor of Psychiatry and Community Health, University of Nottingham

Honorary Consultant Psychiatrist, Nottingham Healthcare Trust

Personal pecuniary interest

Received £1000 from Lundbeck to speak on clinical pathways for bipolar I disorder: implications for commissioning and service delivery at the Changing Faces meeting in London, 31 January 2012. This talk does not review any medication but instead talks about the need for clinical pathways, tariffs and the 2006 NICE bipolar disorder guideline

Mental health theme lead and Director of Research for Collaboration for Leadership in Applied Health Research and Care Nottinghamshire Derbyshire and Lincolnshire until 31st December 2013

Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Non-personal non-pecuniary interestMental health theme lead and Director of Research for the newly funded Collaboration for Leadership in Applied Health Research and Care for the East Midlands from 1 January 2014 to 31 December 2018. The total award is £10 million with £18.4 million matched funding. The Collaboration for Leadership in Applied Health Research and Care is committed to a programme of research that includes sever projects on depression but not any on bipolar disorder at this present time
Action takenNone
Richard Byng
Employment

General Practitioner, Plymouth

Clinical Senior Lecturer, Peninsula Medical School, University of Exeter & Plymouth

Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Non-personal non-pecuniary interestDeputy Director for the existing Collaboration for Leadership in Applied Health Research and Care for the Peninsula which has regained renewed funding from 1 January 2014 to 31 December 2018. The total award for new funding is £10 million. The Collaboration for Leadership in Applied Health Research and Care is committed to a programme of research that includes person-centred care and depression but no focus on bipolar disorder at this present time
Action takenNone
Andrea Cipriani
Employment

Senior Clinical Researcher, Department of Psychiatry, University of Oxford

Honorary Consultant Psychiatrist, Oxford Health NHS Foundation Trust

Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action takenNone
Anthony James
EmploymentConsultant Child and Adolescent Psychiatrist, Highfield Unit; Honorary Senior Lecturer, University of Oxford
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action takenNone
Carnice John
EmploymentRepresenting Service User and Carer views
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action takenNone
Steven Jones
EmploymentProfessor of Clinical Psychology and Director, Spectrum Centre for Mental Health Research, Lancaster University
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action takenNone
Tim McDougall
EmploymentNurse Consultant/Clinical Director, Cheshire and Wirral Partnership NHS Foundation Trust
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action takenNone
Thomas Meyer
EmploymentSenior Lecturer in Clinical Psychology, Institute of Neuroscience, Newcastle University
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interest

Principal investigator of the only publicly funded German randomised controlled trial (RCT) so far evaluating the efficacy of cognitive behavioural therapy (CBT) for bipolar disorders [funding: Deutsche Forschungsgemeinschaft (DFG ME 1681/6-1 to 6.3)]. The publication is in press: Meyer TD, Hautzinger M. (2012). Cognitive behavior therapy and supportive therapy for bipolar disorder. Relapse rates for treatment period and 2 year follow-up? Psychological Medicine

Co-investigator in a new study: ‘A feasibility study of a randomised controlled trial of a family focused treatment (FFT – a UK version) in the management of early onset bipolar disorder’

Action takenNone
Carol Paton
EmploymentChief Pharmacist, Oxleas NHS Foundation Trust
Personal pecuniary interestAttended a one-off advisory board for Sunovion to discuss data related to the use of lurasidone for schizophrenia. Did not participate in any discussions relating to the place of lurasidone in treatment with respect to the NICE bipolar guideline
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action takenNone
Matthias Schwannauer
EmploymentProfessor of Clinical Psychology, University of Edinburgh
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action takenNone
Donna Swinden
EmploymentModern Matron, Acute Adult Inpatients, Tees, Esk and Wear Valleys NHS Foundation Trust
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestCompleted an MSc dissertation in 2009 entitled ’Engaging bipolar patients with cognitive behavioural therapy’ and has presented work at several conferences
Action takenNone
Robert Westhead
EmploymentRepresenting service user and carer views
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action takenTrustee for Bipolar UK
Action TakenNone
Faye Wilson
EmploymentApproved Mental Health Social Worker / Chair, British Association Of Social Workers Mental Health Group
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestChair of Bases Mental Health Forum who are involved in campaigning on the closure of inpatient beds and problems on access to care
Personal non-pecuniary interestNone
Action takenNone
National Collaborating Centre for Mental Health (NCCMH)
Tim Kendall
Employment

Director, NCCMH

Medical Director, Sheffield Health and Social Care Trust Consultant Adult Psychiatrist

Personal pecuniary interest

Grant holder for £1.44 million per year (approximately) from NICE for guidelines work. Work with NICE International

Undertake some research into mental health, and the mental health workforce for Department of Health, Royal College of Psychiatrists and the academy of medical royal colleges

Personal family interestNone
Non-personal pecuniary interestCo-applicant for a £1.7-2 million National Institute for Health Research Health Technology Assessment (HTA) grant for a multicentre, randomised controlled trial of a diabetes intervention to induce weight loss (DESMOND) for people who are overweight and have a severe mental illness, including people with schizophrenia and bipolar disorder.
Personal non-pecuniary interestNone
Action takenNone
Ruth Braidwood
EmploymentResearch Assistant, NCCMH
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action TakenNone
Katherine Leggett
EmploymentSenior Project Manager
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action TakenNone
Elena Marcus
EmploymentResearch Assistant, NCCMH
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action TakenNone
Ifigeneia Mavranezouli
EmploymentSenior Health Economist, NCCMH
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action TakenNone
Evan Mayo-Wilson
EmploymentSenior Systematic Reviewer, NCCMH
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action TakenNone
Sarah Stockton
EmploymentSenior Information Scientist, NCCMH
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action TakenNone
Clare Taylor
EmploymentSenior Editor, NCCMH
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
Action TakenNone
Craig Whittington
EmploymentAssociate Director (Clinical Effectiveness), NCCMH
Personal pecuniary interestNone
Personal family interestNone
Non-personal pecuniary interestNone
Personal non-pecuniary interestNone
© The British Psychological Society & The Royal College of Psychiatrists, 2014.

All rights reserved. No part of this guideline may be reprinted or reproduced or utilised in any form or by any electronic, mechanical, or other means, now known or hereafter invented, or in any information storage or retrieval system, without permission in writing from the National Collaborating Centre for Mental Health. Enquiries in this regard should be directed to the Centre Administrator: ku.ca.hcyspcr@nimdAHMCCN

Bookshelf ID: NBK545979

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